Active contour method for ILM segmentation in ONH volume scans in retinal OCT

The optic nerve head (ONH) is affected by many neurodegenerative and autoimmune inflammatory conditions. Optical coherence tomography can acquire high-resolution 3D ONH scans. However, the ONH's complex anatomy and pathology make image segmentation challenging. This paper proposes a robust approach to segment the inner limiting membrane (ILM) in ONH volume scans based on an active contour method of Chan-Vese type, which can work in challenging topological structures. A local intensity fitting energy is added in order to handle very inhomogeneous image intensities. A suitable boundary potential is introduced to avoid structures belonging to outer retinal layers being detected as part of the segmentation. The average intensities in the inner and outer region are then resealed locally to account for different brightness values occurring among the ONH center. The appropriate values for the parameters used in the complex computational model are found using an optimization based on the differential evolution algorithm. The evaluation of results showed that the proposed framework significantly improved segmentation results compared to the commercial solution

An advanced level set method based on Bregman divergence for inhomogeneous image segmentation

© 2017 IEEE. Intensity inhomogeneity often occurs in real images. Local information based level set methods are comparatively effective in segmenting image with inhomogeneous intensity. However, in practice, these models suffer from local minima and high computational cost. In this paper, a novel region-based level set method based on Bregman divergence and local binary fitting, hereafter referred to as Bregman-LBF, is proposed for image segmentation. The proposed method utilizes global and local information to formulate a new energy function. The Bregman-LBF model enjoys the following advantages: (1) Bregman-LBF outperforms the piece-wise constant(PC) model in handling intensity inhomogeneity. (2) Bregman-LBF is more effective than the local binary fitting (LBF) model and more robust than the global and local intensity fitting (GLIF) model. The relationship between the Bregman-LBF model and the existing models, e.g. the Chan-Vese(CV) model, is discussed. The experiments conducted on synthetic and benchmark image datasets have shown that the proposed Bregman-LBF outperforms the piece-wise constant (PC) model in handling intensity inhomogeneity. The experimental results have also shown that the Bregman-LBF is more effective than the local binary fitting (LBF) model and more robust than the global and local intensity fitting (GLIF) model

Active Contour Models for Manifold Valued Image Segmentation

Image segmentation is the process of partitioning a image into different regions or groups based on some characteristics like color, texture, motion or shape etc. Active contours is a popular variational method for object segmentation in images, in which the user initializes a contour which evolves in order to optimize an objective function designed such that the desired object boundary is the optimal solution. Recently, imaging modalities that produce Manifold valued images have come up, for example, DT-MRI images, vector fields. The traditional active contour model does not work on such images. In this paper, we generalize the active contour model to work on Manifold valued images. As expected, our algorithm detects regions with similar Manifold values in the image. Our algorithm also produces expected results on usual gray-scale images, since these are nothing but trivial examples of Manifold valued images. As another application of our general active contour model, we perform texture segmentation on gray-scale images by first creating an appropriate Manifold valued image. We demonstrate segmentation results for manifold valued images and texture images

Statistical Region Based Segmentation of Ultrasound Images

Segmentation of ultrasound images is a challenging problem due to speckle, which corrupts the image and can result in weak or missing image boundaries, poor signal to noise ratio, and diminished contrast resolution. Speckle is a random interference pattern that is characterized by an asymmetric distribution as well as significant spatial correla- tion. These attributes of speckle are challenging to model in a segmentation approach, so many previous ultrasound segmentation methods simplify the problem by assuming that the speckle is white and/or Gaussian distributed. Unlike these methods, in this paper we present an ultrasound-specific segmentation approach that addresses both the spatial correlation of the data as well as its intensity distribution. We first decorrelate the image and then apply a region-based active contour whose motion is derived from an appropri- ate parametric distribution for maximum likelihood image segmentation. We consider zero-mean complex Gaussian, Rayleigh, and Fisher-Tippett flows, which are designed to model fully formed speckle in the in-phase/quadrature (IQ), envelope detected, and display (log compressed) images, respectively. We present experimental results demon- strating the effectiveness of our method, and compare the results to other parametric and non-parametric active contours

Active Mean Fields for Probabilistic Image Segmentation: Connections with Chan-Vese and Rudin-Osher-Fatemi Models

Segmentation is a fundamental task for extracting semantically meaningful regions from an image. The goal of segmentation algorithms is to accurately assign object labels to each image location. However, image-noise, shortcomings of algorithms, and image ambiguities cause uncertainty in label assignment. Estimating the uncertainty in label assignment is important in multiple application domains, such as segmenting tumors from medical images for radiation treatment planning. One way to estimate these uncertainties is through the computation of posteriors of Bayesian models, which is computationally prohibitive for many practical applications. On the other hand, most computationally efficient methods fail to estimate label uncertainty. We therefore propose in this paper the Active Mean Fields (AMF) approach, a technique based on Bayesian modeling that uses a mean-field approximation to efficiently compute a segmentation and its corresponding uncertainty. Based on a variational formulation, the resulting convex model combines any label-likelihood measure with a prior on the length of the segmentation boundary. A specific implementation of that model is the Chan-Vese segmentation model (CV), in which the binary segmentation task is defined by a Gaussian likelihood and a prior regularizing the length of the segmentation boundary. Furthermore, the Euler-Lagrange equations derived from the AMF model are equivalent to those of the popular Rudin-Osher-Fatemi (ROF) model for image denoising. Solutions to the AMF model can thus be implemented by directly utilizing highly-efficient ROF solvers on log-likelihood ratio fields. We qualitatively assess the approach on synthetic data as well as on real natural and medical images. For a quantitative evaluation, we apply our approach to the icgbench dataset

Automated detection of extended sources in radio maps: progress from the SCORPIO survey

Automated source extraction and parameterization represents a crucial challenge for the next-generation radio interferometer surveys, such as those performed with the Square Kilometre Array (SKA) and its precursors. In this paper we present a new algorithm, dubbed CAESAR (Compact And Extended Source Automated Recognition), to detect and parametrize extended sources in radio interferometric maps. It is based on a pre-filtering stage, allowing image denoising, compact source suppression and enhancement of diffuse emission, followed by an adaptive superpixel clustering stage for final source segmentation. A parameterization stage provides source flux information and a wide range of morphology estimators for post-processing analysis. We developed CAESAR in a modular software library, including also different methods for local background estimation and image filtering, along with alternative algorithms for both compact and diffuse source extraction. The method was applied to real radio continuum data collected at the Australian Telescope Compact Array (ATCA) within the SCORPIO project, a pathfinder of the ASKAP-EMU survey. The source reconstruction capabilities were studied over different test fields in the presence of compact sources, imaging artefacts and diffuse emission from the Galactic plane and compared with existing algorithms. When compared to a human-driven analysis, the designed algorithm was found capable of detecting known target sources and regions of diffuse emission, outperforming alternative approaches over the considered fields.Comment: 15 pages, 9 figure