1,221 research outputs found

    Reclamation of Surface-Mined Land

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    Author Institution: USDA Forest Service, NE Forest Experiment Station, Forest Products Marketing LaboratoryPLASS, WILLIAM T. Reclamation of surface mined lands. Ohio J. Sci. 75(6): 298, 1975

    On the testability of coarsening assumptions: a hypothesis test for subgroup independence

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    Since coarse(ned) data naturally induce set-valued estimators, analysts often assume coarsening at random (CAR) to force them to be single-valued. Focusing on a coarse categorical response variable and a precisely observed categorical covariate, we re-illustrate the impossibility to test CAR and contrast it to another type of coarsening called subgroup independence (SI), using the data of the German Panel Study ``Labour Market and Social Security'' as an example. It turns out that -- depending on the number of subgroups and categories of the response variable -- SI can be point-identifying as CAR, but testable unlike CAR. A main goal of this paper is the construction of the likelihood-ratio test for SI. All issues are similarly investigated for the here proposed generalized versions, gCAR and gSI, thus allowing a more flexible application of this hypothesis test

    Interplay of Strain Relaxation and Chemically Induced Diffusion Barriers: Nanostructure Formation in 2D Alloys

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    We study the formation of nanostructures with alternating stripes composed of bulk-immiscible adsorbates during submonolayer heteroepitaxy. We evaluate the influence of two mechanisms considered in the literature: (i) strain relaxation by alternating arrangement of the adsorbate species, and (ii) kinetic segregation due to chemically induced diffusion barriers. A model ternary system of two adsorbates with opposite misfit relative to the substrate, and symmetric binding is investigated by off-lattice as well as lattice kinetic Monte Carlo simulations. We find that neither of the mechanisms (i) or (ii) alone can account for known experimental observations. Rather, a combination of both is needed. We present an off-lattice model which allows for a qualitative reproduction of stripe patterns as well as island ramification in agreement with recent experimental observations for CoAg/Ru(0001) [R. Q. Hwang, Phys. Rev. Lett. 76, 4757 (1996)]. The quantitative dependencies of stripe width and degree of island ramification on the misfit and interaction strength between the two adsorbate types are presented. Attempts to capture essential features in a simplified lattice gas model show that a detailed incorporation of non-local effects is required.Comment: 24 pages, 12 figure

    Aspects of electrostatics in a weak gravitational field

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    Several features of electrostatics of point charged particles in a weak, homogeneous, gravitational field are discussed using the Rindler metric to model the gravitational field. Some previously known results are obtained by simpler and more transparent procedures and are interpreted in an intuitive manner. Specifically: (i) We show that the electrostatic potential of a charge at rest in the Rindler frame is expressible as A_0=(q/l) where l is the affine parameter distance along the null geodesic from the charge to the field point. (ii) We obtain the sum of the electrostatic forces exerted by one charge on another in the Rindler frame and discuss its interpretation. (iii) We show how a purely electrostatic term in the Rindler frame appears as a radiation term in the inertial frame. (In part, this arises because charges at rest in a weak gravitational field possess additional weight due to their electrostatic energy. This weight is proportional to the acceleration and falls inversely with distance -- which are the usual characteristics of a radiation field.) (iv) We also interpret the origin of the radiation reaction term by extending our approach to include a slowly varying acceleration. Many of these results might have possible extensions for the case of electrostatics in an arbitrary static geometry. [Abridged Abstract]Comment: 26 pages; accepted for publication in Gen.Rel.Gra

    Rural continental aerosol properties and processes observed during the Hohenpeissenberg Aerosol Characterization Experiment (HAZE2002)

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    International audienceDetailed investigations of the chemical and microphysical properties of rural continental aerosols were performed during the HAZE2002 experiment, which was conducted in May 2002 at the Meteorological Observatory Hohenpeissenberg (DWD) in Southern Germany. Online measurements included: Size-resolved chemical composition of submicron particles; total particle number concentrations and size distributions over the diameter range of 3 nm to 9 ?m; gas-phase concentration of monoterpenes, CO, O3, OH, and H2SO4. Filter sampling and offline analytical techniques were used to determine: Fine particle mass (PM2.5), organic, elemental and total carbon in PM2.5 (OC2.5, EC2.5, TC2.5), and selected organic compounds (dicarboxylic acids, polycyclic aromatic hydrocarbons, proteins). Overall, the non-refractory components of submicron particles detected by aerosol mass spectrometry (PM1, 6.6±5.4 ?g m?3, arithmetic mean and standard deviation) accounted for ~62% of PM2.5 determined by filter gravimetry (10.6±4.7 ?g m?3). The relative proportions of non-refractory submicron particle components were: (23±39)% ammonium nitrate, (27±23)% ammonium sulfate, and (50±40)% organics (OM1). OM1 was closely correlated with PM1 (r2=0.9) indicating a near-constant ratio of non-refractory organics and inorganics. The average ratio of OM1 to OC2.5 was 2.1±1.4, indicating a high proportion of heteroelements in the organic fraction of the sampled rural aerosol. This is consistent with the high ratio of oxygenated organic aerosol (OOA) over hydrocarbon-like organic aerosol (HOA) inferred from the AMS results (4:1), and also with the high abundance of proteins (~3%) indicating a high proportion of primary biological material (~30%) in PM2.5. This finding was confirmed by low abundance of PAHs (?3) and EC (?3) in PM2.5 and detection of several secondary organic aerosol compounds (dicarboxylic acids) and their precursors (monoterpenes). New particle formation was observed almost every day with particle number concentrations exceeding 104 cm?3 (nighttime background level 1000?2000 cm?3). Closer inspection of two major events indicated that the observed nucleation agrees with ternary H2SO4/H2O/NH3 nucleation and that condensation of both organic and inorganic species contributed to particle growth

    Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing

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    <p>Abstract</p> <p>Background</p> <p>Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a repressive mode of inactive genes. Less clear is whether this cooperation is generalized in mammalian genomes, such as mouse genome. Here we use epigenomic tools to simultaneously interrogate chromatin modifications and DNA methylation in a mouse leukemia cell line, L1210.</p> <p>Results</p> <p>Histone modifications on H3K9 and DNA methylation in L1210 were profiled by both global CpG island array and custom mouse promoter array analysis. We used chromatin immunoprecipitation microarray (ChIP-chip) to examine acetyl-H3K9 and dimethyl-H3K9. We found that the relative level of acetyl-H3K9 at different chromatin positions has a wider range of distribution than that of dimethyl-H3K9. We then used differential methylation hybridization (DMH) and the restriction landmark genome scanning (RLGS) to analyze the DNA methylation status of the same targets investigated by ChIP-chip. The results of epigenomic profiling, which have been independently confirmed for individual loci, show an inverse relationship between DNA methylation and histone acetylation in regulating gene silencing. In contrast to the previous notion, dimethyl-H3K9 seems to be less distinct in specifying silencing for the genes tested.</p> <p>Conclusion</p> <p>This study demonstrates in L1210 leukemia cells a diverse relationship between histone modifications and DNA methylation in the maintenance of gene silencing. Acetyl-H3K9 shows an inverse relationship between DNA methylation and histone acetylation in regulating gene silencing as expected. However, dimethyl-H3K9 seems to be less distinct in relation to promoter methylation. Meanwhile, a combination of epigenomic tools is of help in understanding the heterogeneity of epigenetic regulation, which may further our vision accumulated from single-gene studies.</p

    Bright single-photon sources in bottom-up tailored nanowires

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    The ability to achieve near-unity light extraction efficiency is necessary for a truly deterministic single photon source. The most promising method to reach such high efficiencies is based on embedding single photon emitters in tapered photonic waveguides defined by top-down etching techniques. However, light extraction efficiencies in current top-down approaches are limited by fabrication imperfections and etching induced defects. The efficiency is further tempered by randomly positioned off-axis quantum emitters. Here, we present perfectly positioned single quantum dots on the axis of a tailored nanowire waveguide using bottom-up growth. In comparison to quantum dots in nanowires without waveguide, we demonstrate a 24-fold enhancement in the single photon flux, corresponding to a light extraction efficiency of 42 %. Such high efficiencies in one-dimensional nanowires are promising to transfer quantum information over large distances between remote stationary qubits using flying qubits within the same nanowire p-n junction.Comment: 19 pages, 6 figure

    Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations.

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    BackgroundRestriction landmark genomic scanning (RLGS) is one of the most successfully applied methods for the identification of aberrant CpG island hypermethylation in cancer, as well as the identification of tissue specific methylation of CpG islands. However, a limitation to the utility of this method has been the ability to assign specific genomic sequences to RLGS spots, a process commonly referred to as "RLGS spot cloning."ResultsWe report the development of a virtual RLGS method (vRLGS) that allows for RLGS spot identification in any sequenced genome and with any enzyme combination. We report significant improvements in predicting DNA fragment migration patterns by incorporating sequence information into the migration models, and demonstrate a median Euclidian distance between actual and predicted spot migration of 0.18 centimeters for the most complex human RLGS pattern. We report the confirmed identification of 795 human and 530 mouse RLGS spots for the most commonly used enzyme combinations. We also developed a method to filter the virtual spots to reduce the number of extra spots seen on a virtual profile for both the mouse and human genomes. We demonstrate use of this filter to simplify spot cloning and to assist in the identification of spots exhibiting tissue-specific methylation.ConclusionThe new vRLGS system reported here is highly robust for the identification of novel RLGS spots. The migration models developed are not specific to the genome being studied or the enzyme combination being used, making this tool broadly applicable. The identification of hundreds of mouse and human RLGS spot loci confirms the strong bias of RLGS studies to focus on CpG islands and provides a valuable resource to rapidly study their methylation
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