Feeding specific amino acids to increase redberry juniper consumption by goats

Redberry juniper (Juniperus pinchotii Sudw.) is a chemically defended, invasive brush species in western states. Previous research has demonstrated that goats supplemented with escape protein sources will consume a higher volume of juniper. In this study I attempted to increase the intake of juniper by recently weaned, Boer-Spanish cross goats (n = 30) by randomly placing them into four treatments and a control, and supplementing each treatment group with one of the following amino acids: arginine, proline, leucine, and glutamine. Treatments did not have a significant effect on juniper intake (P > 0.05). All goats increased intake over time (P > 0.05). Goats exhibited significant weight gain over the course of the study (P < 0.05). Blood serum metabolites were within normal limits. Future studies on escape protein supplementation may provide a better understanding of small ruminant physiology in relationship to intake of juniper

Climate cosmopolitics and the possibilities for urban planning

Cosmopolitical action in a climate-changed city represents different knowledges and practices that may seem disconnected but constellate to frame stories and spaces of a climate-just city. The question this article asks is: how might we as planners identify and develop counter-hegemonic praxes that enable us to re-imagine our experience of, and responses to, climate change? To explore this question, we draw on Isabelle Stengers's (2010) idea of cosmopolitics-where diverse stories, perspectives, experiences, and practices can connect to create the foundation for new strategic possibilities. Our article is empirically informed by conversations with actors from three Australian cities (Sydney, Brisbane, and Perth) who are mobilizing different approaches to this ideal in various grassroots actions on climate change

Environmental Imaginaries: Climate Change as an Object of Urban Governance

Not availabl

Algal Growth Potentials and Heavy Metal Concentrations of the Primary Streams to Upper Beaver Lake

Meyer and Green (1984) demonstrated the probable inhibition of algal growth potential by heavy metals in upper Beaver Lake. Upper Beaver Lake receives water from three tributaries. One contains a small reservoir and the combined streams receive sewage input. Collections were made approximately monthly at eight sites for the Algal Assay Bottle Test (AABT) and heavy metal analysis. In general, AABT results indicated that the collections above the sewage lnput were phosphorus limited while those below were nitrogen or combined nitrogen and phosphorus limited. Growth inhibition occurred during summer and early fall at various sites with greater inhibition at the confluence of the streams. No inhibitions occurred, at the site below the sewage input. Heavy metal concentrations had an overall tendency to increase downstream. Values within the small reservoir were 50-100% higher than in the feeder stream. Highest values of Pb were observed below the reservoir. SO4 ,Cl, Mg, Ca, Na and K had high values during low flow in August-ctober. The low values were independent of high flow. Pb followed an independent pattern. Storm event results showed that the Ca maximum was before the hydrographic peak while Fe, Mn, Pb, In, Co, Ni, Cu and Cd attained their maximum just after the peak. Maximum values were 4-10 times background values. Mn, Pb and Fe exceeded EPA recommended standards for drinking water

Expressions 1988

https://openspace.dmacc.edu/expressions/1031/thumbnail.jp

The Baryon Oscillation Spectroscopic Survey of SDSS-III

The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the scale of baryon acoustic oscillations (BAO) in the clustering of matter over a larger volume than the combined efforts of all previous spectroscopic surveys of large scale structure. BOSS uses 1.5 million luminous galaxies as faint as i=19.9 over 10,000 square degrees to measure BAO to redshifts z<0.7. Observations of neutral hydrogen in the Lyman alpha forest in more than 150,000 quasar spectra (g<22) will constrain BAO over the redshift range 2.15<z<3.5. Early results from BOSS include the first detection of the large-scale three-dimensional clustering of the Lyman alpha forest and a strong detection from the Data Release 9 data set of the BAO in the clustering of massive galaxies at an effective redshift z = 0.57. We project that BOSS will yield measurements of the angular diameter distance D_A to an accuracy of 1.0% at redshifts z=0.3 and z=0.57 and measurements of H(z) to 1.8% and 1.7% at the same redshifts. Forecasts for Lyman alpha forest constraints predict a measurement of an overall dilation factor that scales the highly degenerate D_A(z) and H^{-1}(z) parameters to an accuracy of 1.9% at z~2.5 when the survey is complete. Here, we provide an overview of the selection of spectroscopic targets, planning of observations, and analysis of data and data quality of BOSS.Comment: 49 pages, 16 figures, accepted by A

Does egg deposition by herbivorous pine sawflies affect transcription of sesquiterpene synthases in pine?

Scots pine (Pinus sylvestris; Pinaceae, Pinales) is known to defend against egg deposition by herbivorous sawflies by changing its terpenoid volatile blend. The oviposition-induced pine odor attracts egg parasitoids that kill the sawfly eggs. Here, we investigated whether sawfly egg deposition activates genes encoding pine terpene synthases by extracting mRNA from oviposition-induced P. sylvestris. Three new sesquiterpene synthases, PsTPS 1, PsTPS 2, and PsTPS 3, were isolated that were shown on heterologous expression in Escherichia coli to produce (E)-β-caryophyllene and α-humulene (PsTPS 1), 1(10),5-germacradiene-4-ol (PsTPS 2), and longifolene and α-longipinene (PsTPS 3) as their principal products. Quantitative RT-PCR analyses revealed that transcript levels of PsTPS 1 and PsTPS 2 were significantly higher in oviposition-induced twigs that were attractive to the parasitoids than in non-attractive, artificially damaged twigs. Thus, our results demonstrate a specific transcription response to egg deposition, distinct from that caused by artificial wounding. Transcripts of PsTPS 3 did not change in response to egg deposition. The transcript levels of PsTPS 1, PsTPS 2, and PsTPS 3 were also determined in relation to time after egg deposition, since pine odor is attractive to the parasitoid only 72 h after egg deposition. Transcription rates of PsTPS 1 and PsTPS 2 were significantly enhanced only 72 h after egg deposition, thus matching the timing of odor attractiveness, while for PsTPS 3, enhanced transcription was not detected at any time period studied after egg deposition. The ecological significance of the oviposition-induced increase of sesquiterpene synthase transcripts is discussed

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin