QUALITY OF LIFE IN TYPE-I DIABETES MELLITUS PATIENTS WITH DIABETIC VEGETOPATHY

"Quality of life" represents one of the most important parameters of individual coping the problems of social adaptation in case of persisting manifestations of the basic disease. A total of 46 type I diabetes mellitus patients with diabetic vegetopathy were examined. Diagnosis was anamnestically and instrumentally verified. Patients' quality of life was investigated using MMP1 in a Kincannon's variant, Zungs depression scale, and Spitcer's quality-of-life scale. The following code was established: schizoidia - psychasthenia - hypochondria - paranoia. According to the depression scale, there was a slight depression in 51,7 per cent of the patients, a moderate - in 36,5 per cent but a severe - in 13,7 per cent. According to the quality-of-life scale, the parameter of self-confidence was characterized as poor in 17,3 per cent of the cases, moderately good - in 31 per cent but good - in 51,7 per cent. Social adaptation was poor in 6,8 per cent of the patients, moderately good - in 31 per cent but good - in 62,2 per cent. The correlation between the expression of vegetopathy, the severity of diabetes mellitus, the self-confidence, social adaptation and "social inertia" was discussed

SOME PROBLEMS OF THE TIMELY DIAGNOSIS, TREATMENT AND REHABILITATION OF PATIENTS WITH ALLERGIC BRONCHO-OBSTRUCTIVE DISEASES

No abstrac

The influence of different doses and ratios of mineral fertilizers on the yield of winter rye in the Urals

Winter rye is an important crop of the Non-Chernozem belt of Russia, the productivity of which depends on the use of fertilizers. The paper presents data on the agronomic and economic efficiency of cultivating Falenskaya 4 winter rye under conditions of long-term use of mineral fertilizers. The studies were carried out in 2019-2021 in Perm Region on sod-podzolic heavy loamy soil in a long-term stationary experiment based on a reduced factorial design (6x6x6) with a wide range of doses and NPK ratios. The highest yield in 2019 was obtained in N30P120K120 variant (3.07 t/ha), the highest payback of mineral fertilizers by grain was noted in N90 and N30P30K30 variants (6.00 and 5.69 kg of grain). The highest yield and payback of grain in the conditions of 2021 and for two years of research in average was obtained in the variant N90: in 2021, 3.01 t/ha and 13.96 kg of grain, for 2 years average – 2.95 t/ha and 9.82 kg of grain. The efficiency of nitrogen fertilizers has been proved by a regression equation for two years average, phosphoric and potash fertilizers did not have a significant effect. The rise in the yield increase occurred up to a nitrogen dose of 90 kg/ha and amounted to 0.42 t/ha at N90. The highest payback by grain was noted among nitrogen treatments – by N30 (7.3 kg of grain), with each increase in doses by 30 kg/ha, this indicator decreased linearly by 1.3 kg. The highest profitability over the years of research was obtained in the variant without fertilizers– 60 %, over two years in average. The profitability of using N90 was higher compared with the control only in 2021 – 50 % versus 43 %. All the studied doses of nitrogen used separately provided positive profitability, but the most cost-effective was the use of N30 and N60 – profitability was 52 and 45 %, respectively

Continuous selections of multivalued mappings

This survey covers in our opinion the most important results in the theory of continuous selections of multivalued mappings (approximately) from 2002 through 2012. It extends and continues our previous such survey which appeared in Recent Progress in General Topology, II, which was published in 2002. In comparison, our present survey considers more restricted and specific areas of mathematics. Note that we do not consider the theory of selectors (i.e. continuous choices of elements from subsets of topological spaces) since this topics is covered by another survey in this volume

Environmental Assessment of Soil for Monitoring Volume I: Indicators & Criteria

The ENVASSO Project (Contract 022713) was funded 2006-8, under the European Commission 6th Framework Programme of Research, with the objective of defining and documenting a soil monitoring system appropriate for soil protection at continental level. The ENVASSO Consortium, comprising 37 partners drawn from 25 EU Member States, reviewed soil indicators, identified existing soil inventories and monitoring programmes in the Member States, designed and programmed a database management system to capture, store and supply soil profile data, and drafted procedures and protocols appropriate for inclusion in a European soil monitoring network of sites that are geo-referenced and at which a qualified sampling process is or could be conducted. Volume I, one of six describing the results of the ENVASSO Project, identifies 290 potential indicators relating to 188 key issues for the following nine threats to soil: erosion, organic matter decline, contamination, sealing, compaction, loss of biodiversity, salinisation, landslides and desertification. Sixty candidate indicators that address 27 key issues, covering all these threats, were selected on the basis of their thematic relevance, policy relevance and data availability. Baseline and threshold values are presented and detailed Fact Sheets describe three priority indicators for each soil threat.JRC.DDG.H.7-Land management and natural hazard

Concept of use of comprehensive fertilizers of long-term action on the basis of waste processing of potassium-magnesium ore as a new paradigm in improving soil fertility

Technology for the production and use of new multiple slow-release fertilizers from clay-salt waste (sludge) remaining as a result of potassium fertilizers production from natural K-Mg ores, is elaborated in Perm Federal Research Center. The main processes in the technology are waste enrichment and subsequent high-temperature calcination of the enriched concentrate. As a result, the product, received the name the calcine of clay-salt sludge, was formed having the properties of multiple slow-release fertilizer and ameliorant. Laboratory and field experiments on the calcine use as a potassium fertilizer were fulfilled. The studied crops were spring wheat, barley, and potato. The experimental scheme included such treatments: control (without fertilizers), NP – background; NP + KCl and NP + calcine. The use of calcine for grain crops (wheat, barley) on the NP background promoted the yield gains by 1.7–1.9 t/ha compared with the control, the use of standard NPK fertilizers – by 1.8–2.0 t/ha, the difference was within the error of the experiment (HCP05 = 0.21; 0.38 t/ha). The content of nitrogen, phosphorus and potassium in the grain and straw of both crops in the treatments using calcine was approximately equal to the variants using standard fertilizer and significantly higher compared to the control. Differences between calcine treatments were not significant. The application of N90P90 and full mineral fertilizer (N90P90K90) contributed to the yield increase of potato tubers by 1.43–4.51 t/ha respectively. The use of unconventional potassium fertilizer – calcine on the background of NP was not inferior in efficiency to the use of traditional fertilizer – potassium chloride. The quality parameters of the potato crop (dry matter and starch content in tubers, the content of heavy metals) were also not inferior compared to the use of traditional potassium fertilizer. The use of calcine for potato and cereals in rates equal to K60-120 did not lead to deterioration of the fertility indicators of sod-podzolic soil. Upon receipt of the cinder, one can use the additional unlimited set of components. In other words, this is a conceptual model for creating new types of mineral fertilizers with desired properties for different soil and climatic conditions and crops with different requirements for mineral nutrition

Mapping of the current transition of care practice for patients with pituitary disease at Endo-ERN reference centers

Rare endocrine conditions present specific diagnostic and management challenges for healthcare providers, one of which is the understudied transition of care. Despite the need for guidance regarding transition, consensus on structured and protocolled approaches is lacking. Therefore, we aimed to map the current clinical practice and identify unmet needs regarding transition of care for patients with pituitary disease in the reference centers (RCs) of the European Reference Network on Rare Endocrine Conditions (Endo-ERN). A survey-based, cross-sectional study using the EU Survey tool was performed and completed by 46 physicians (n) from 30 RCs (N). Transition is a common practice among RCs (n = 44/46), usually accomplished by a multidisciplinary team meeting (N = 20/30). Criteria for start and end of transition were defined in half of the RCs, with 16.7% of centers providing dissimilar answers. Transition readiness was assessed by >75% of the RCs, mostly by unvalidated means (e.g. subjective opinions, informal consultations). Pituitary-specific transition assessment tool was applied in one RC only. Transition protocols were present in only 9% of RCs, while in many RCs, transition decisions were taken in combined adult-pediatric meetings or based on clinicians' personal judgment. A minority of physicians evaluated the effectiveness of transition-related interventions (n = 11/46) or medical outcomes (n = 8/46). Patient-reported outcome measures were infrequently used (n = 4/46). Identified unmet needs included the development of guidelines (n = 5/46) and EU-wide approach (n = 2/46). This study exemplifies the unmet needs for a structural definition of the transition period and transition management for patients with rare hypothalamic and pituitary conditions from healthcare providers' perspective.Metabolic health: pathophysiological trajectories and therap

ГИДРОДИНАМИЧЕСКОЕ СОПРОТИВЛЕНИЕ УНИФИЦИРОВАННОГО МОДУЛЬНОГО РЕКУПЕРАТОРА НАГРЕВАТЕЛЬНЫХ И ТЕРМИЧЕСКИХ ПЕЧЕЙ ЗАГОТОВИТЕЛЬНОГО И МЕХАНОСБОРОЧНОГО КОМПЛЕКСОВ МАШИНОСТРОИТЕЛЬНЫХ И АВТОТРАКТОРНЫХ ЗАВОДОВ

Analysis of hydrodynamic resistance of gas and air paths of a recuperator assembled with the help of unified module elements M-I and M-II has been carried out. The paper shows the possibility to change path resistance within a wide range of values. Выполнен анализ гидродинамического сопротивления газового и воздушного трактов рекуператора, собранного из унифицированных модульных элементов М-I и М-II. Показана возможность изменения сопротивления трактов в широком диапазоне значений

К расчету унифицированного модульного рекуператора (модули М-I и М-II) для нагревательных и термических печей заготовительного и механосборочного производств машиностроительных и автотракторных заводов Республики Беларусь

The paper shows an influence of outside ribbing of heat-exchange surface of unified modules M-I and M-II on heat transfer factor of the proposed recuperator and its hydro-dynamic resistance.Показано влияние наружного оребрения поверхности теплообмена унифицированных модулей М-I и М-II на коэффициент теплопередачи предлагаемого рекуператора и его гидродинамическое сопротивление

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Correction: Volume: 10 Issue: 1 Article Number: 44 DOI: 10.1186/s13601-020-00351-w Published: OCT 26 2020Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.Peer reviewe