Estudio agronomico de la explotacion intercalada de sorgo (Sorghun bicolor L.-) y frijol (Phaseolus sp)

El trabajo fue realizado en la Granja Experimental de la Secretaría de Fomento del Departamento del Magdalena en el Municipio de Santa Marta. La zona se caracteriza por presentar las siguientes condiciones: Altura sobre el nivel del mar 14 m. Temperatura media anual 28o C Precipitación media anual 640 mm Humedad relativa media anual 75%. Los objetivos del trabajo fueron: Conocer el comportamiento del frijol y sorgo cuando se cultivan en sistema intercalado. Determinar qué tipo de intercalación entre sorgo y frijol es el más rentable. El diseño empleado, fue el de bloques al azar con 6 tratamientos y 3 replicaciones. El suelo usado presentó un pH de 7,3 y un contenido de materia orgánica de 2,7. Los tratamientos usados fueron: sorgo sembrado a 1,2 m. entre líneas y entre ellas 2 líneas de frijol a 40 cm., sorgo sembrado a 1,2 m. entre línea y entre ellas una línea de frijol a 60 cm, sorgo sembrado a 1 m. entre líneas y entre ellas una línea de frijol a 50 cm., sorgo sembrado a 80 cm, entre líneas y entre ellas una línea de frijol a 40 cm., sorgo sólo a 80 cm. entre líneas y frijol sólo a 60 cm. entre líneas. Los rendimientos tanto para sorgo como para frijol siempre son menores en la intercalación que cuando se cultivan solos, pero la intercalación siempre produce mayor ingresos, siendo la mejor alternativa, cultivar sorgo a 80 cm. entre líneas y colocarle una línea de frijol en medio de la calle a 40 cm. de distancia

Diseño de un sistema productivo sustentable para producción de panela en el municipio de Nariño, Antioquia

Colombia es un país reconocido por la producción de panela a nivel mundial, pero con inconvenientes en sus métodos de realización del producto, por ser muy artesanales en varios lugares del territorio. Esto motivó a realizar este estudio para un diseño de un sistema productivo sustentable de panela en el Municipio de Nariño, Antioquia por su tradición en la elaboración de este tipo de productos. El diseño se elabora a partir de diagramaciones que muestren las actividades del proceso y determinando la tecnología que se desea implementar, siendo un punto decisivo en la manera de producción de la panela; por último, se hace la distribución más pertinente en los centros de trabajo, teniendo en cuenta las medidas en las áreas de los diversos lugares de producción y que sirva finalmente como base para las personas de la región que deseen emprender en la producción de panela, una forma amigable con el ambienteColombia is a country recognized for the production of panela worldwide, but with drawbacks in its methods of making the product, for being very traditional in various parts of the territory. This motivated to carry out this study for a design of a sustainable panela production system in the Municipality of Nariño, Antioquia due to its tradition in the elaboration of this type of products. The design is made from diagrams that show the activities of the process and determining the technology to be implemented, being a decisive point in the way of production of the panela; Finally, the most pertinent distribution is made in the work centers, taking into account the measures in the areas of the various places of production and that finally serves as a base for the people of the region who wish to undertake the production of panela, an environmentally friendly wayRionegr

Diseño de un sistema productivo sustentable para producción de panela en el municipio de Nariño, Antioquia

Colombia es un país reconocido por la producción de panela a nivel mundial, pero con inconvenientes en sus métodos de realización del producto, por ser muy artesanales en varios lugares del territorio. Esto motivó a realizar este estudio para un diseño de un sistema productivo sustentable de panela en el Municipio de Nariño, Antioquia por su tradición en la elaboración de este tipo de productos. El diseño se elabora a partir de diagramaciones que muestren las actividades del proceso y determinando la tecnología que se desea implementar, siendo un punto decisivo en la manera de producción de la panela; por último, se hace la distribución más pertinente en los centros de trabajo, teniendo en cuenta las medidas en las áreas de los diversos lugares de producción y que sirva finalmente como base para las personas de la región que deseen emprender en la producción de panela, una forma amigable con el ambienteColombia is a country recognized for the production of panela worldwide, but with drawbacks in its methods of making the product, for being very traditional in various parts of the territory. This motivated to carry out this study for a design of a sustainable panela production system in the Municipality of Nariño, Antioquia due to its tradition in the elaboration of this type of products. The design is made from diagrams that show the activities of the process and determining the technology to be implemented, being a decisive point in the way of production of the panela; Finally, the most pertinent distribution is made in the work centers, taking into account the measures in the areas of the various places of production and that finally serves as a base for the people of the region who wish to undertake the production of panela, an environmentally friendly wayRionegr

Individualized exercises for continuous assessment in engineering

This project focuses on the development of a web application that automatically grades the solution to engineering exercises. The input data of each exercise is different for each student in order to reduce plagiarism and increase motivation. Students can access the web app from any device with internet access (computer, laptop, phone, …) at any time. The fact that the exercises are enunciated and evaluated in an individualized way eliminates the possibility for students to share the solutions and divert the profitable collaboration between students towards the learning of the resolution procedure itself. From the professor’s perspective, this tool allows an efficient and continuous evaluation of students. Besides, the storage of the data (number of attempts, time required, etc.) provides valuable information both for the self-assessment of the professor and for the analysis of the individualized learning process of each student. The web application is coded in Python, which easily allows the incorporation of additional features according to the needs of professors and students. The web application has already been tested during two academic years in two Spanish universities and for several engineering degrees. Ten professor and more than 2000 students have already benefit from this web application.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Diagnosis of Induction Motor Faults in the Fractional Fourier Domain

[EN] Motor current signature analysis (MCSA) is a well-established method for the diagnosis of induction motor faults. It is based on the analysis of the spectral content of a motor current, which is sampled while a motor runs in steady state, to detect the harmonic components that characterize each type of fault. The Fourier transform (FT) plays a prominent role as a tool for identifying these spectral components. Recently, MCSA has also been applied during the transient regime (TMCSA) using the whole transient speed range to create a unique stamp of each harmonic as it evolves in the time-frequency plane. This method greatly enhances the reliability of the diagnostic process compared with the traditional method, which relies on spectral analysis at a single speed. However, the FT cannot be used in this case because the fault harmonics are not stationary signals. This paper proposes the use of the fractional FT (FrFT) instead of the FT to perform TMCSA. This paper also proposes the optimization of the FrFT to generate a spectrum where the frequency-varying fault harmonics appear as single spectral lines and, therefore, facilitate the diagnostic process. A discrete wavelet transform (DWT) is used as a conditioning tool to filter the motor current prior to its processing by the FrFT. Experimental results that are obtained with a 1.1-kW three-phase squirrel-cage induction motor with broken bars are presented to validate the proposed method.This work was supported by the European Community's Seventh Framework Program FP7/2007-2013 under Grant Agreement 224233 (Research Project PRODI "Power Plant Robustification Based on Fault Detection and Isolation Algorithms"). The Associate Editor coordinating the review process for this paper was Dr. Subhas Mukhopadhyay.Pineda-Sanchez, M.; Riera-Guasp, M.; Antonino-Daviu, J.; Roger-Folch, J.; Perez-Cruz, J.; Puche-Panadero, R. (2010). Diagnosis of Induction Motor Faults in the Fractional Fourier Domain. IEEE Transactions on Instrumentation and Measurement. 59(8):2065-2075. https://doi.org/10.1109/TIM.2009.2031835S2065207559

The tomato mutant ars1 (altered response to salt stress 1) identifies an R1-type MYB transcription factor involved in stomatal closure under salt acclimation

[EN] A screening under salt stress conditions of a T-DNA mutant collection of tomato (Solanum lycopersicum L.) led to the identification of the altered response to salt stress 1 (ars1) mutant, which showed a salt-sensitive phenotype. Genetic analysis of the ars1 mutation revealed that a single T-DNA insertion in the ARS1 gene was responsible of the mutant phenotype. ARS1 coded for an R1-MYB type transcription factor and its expression was induced by salinity in leaves. The mutant reduced fruit yield under salt acclimation while in the absence of stress the disruption of ARS1 did not affect this agronomic trait. The stomatal behaviour of ars1 mutant leaves induced higher Na+ accumulation via the transpiration stream, as the decreases of stomatal conductance and transpiration rate induced by salt stress were markedly lower in the mutant plants. Moreover, the mutation affected stomatal closure in a response mediated by abscisic acid (ABA). The characterization of tomato transgenic lines silencing and overexpressing ARS1 corroborates the role of the gene in regulating the water loss via transpiration under salinity. Together, our results show that ARS1 tomato gene contributes to reduce transpirational water loss under salt stress. Finally, this gene could be interesting for tomato molecular breeding, because its manipulation could lead to improved stress tolerance without yield penalty under optimal culture conditions.This work was funded by a research project (AGL2012-40150-C01/C02/C03) from the Spanish Ministry of Economy and Competitiveness (MINECO). This work was also supported by grant RYC2010-06369 (Ramon y Cajal Programme) from the MINECO to NF-G and grant E-30-2011-0443170 (JAE-Doc Programme) from the Spanish Council of Scientific Research (CSIC) to IE and BP. The authors have no conflict of interests to declareCampos, JF.; Cara, B.; Perez-Martin, F.; Pineda Chaza, BJ.; Egea, I.; Flores, FB.; Fernandez-Garcia, N.... (2016). The tomato mutant ars1 (altered response to salt stress 1) identifies an R1-type MYB transcription factor involved in stomatal closure under salt acclimation. Plant Biotechnology Journal. 14(6):1345-1356. https://doi.org/10.1111/pbi.124981345135614

Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment

Brain metastases are the most common tumor of the brain with a dismal prognosis. A fraction of patients with brain metastasis benefit from treatment with immune checkpoint inhibitors (ICI) and the degree and phenotype of the immune cell infiltration has been used to predict response to ICI. However, the anatomical location of brain lesions limits access to tumor material to characterize the immune phenotype. Here, we characterize immune cells present in brain lesions and matched cerebrospinal fluid (CSF) using single-cell RNA sequencing combined with T cell receptor genotyping. Tumor immune infiltration and specifically CD8 + T cell infiltration can be discerned through the analysis of the CSF. Consistently, identical T cell receptor clonotypes are detected in brain lesions and CSF, confirming cell exchange between these compartments. The analysis of immune cells of the CSF can provide a non-invasive alternative to predict the response to ICI, as well as identify the T cell receptor clonotypes present in brain metastasis. The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in the tumo

Potential relation of cardiovascular risk factors to disease activity in patients with axial spondyloarthritis

Background: Axial spondyloarthritis (axSpA) patients are known to have a higher prevalence of several comorbidities, including, among others, an increased risk of atherosclerosis, hypertension, dyslipidemia, and diabetes. The purpose of the present study was to determine whether the sum of traditional cardiovascular (CV) risk factors is related to disease characteristics, such as disease activity, in patients with axSpA. Methods: A cross-sectional study that encompassed 804 patients with axSpA was conducted. Patients were assessed for the presence of five traditional CV risk factors (diabetes mellitus, dyslipidemia, hypertension, obesity, and smoking status), and disease activity measurements. A multivariable regression analysis was performed to evaluate whether the number of classic CV risk factors was independently associated with specific features of the disease, to include disease activity. Results: A multivariable analysis showed that Ankylosing Spondylitis Disease Activity Score-C reactive protein (ASDAS-CRP) activity score was significantly higher in patients with 1 [beta coefficient 0.3 (95% confidence interval (CI) 0.1-0.5), p = 0.001] and ?2 [beta coefficient 0.5 (95% CI 0.3-0.7), p = 0.000] CV risk factors compared with those without CV risk factors. Similarly, patients with 1 [OR 2.00 (95%CI 0.99-4.02), p = 0.053] and ?2 [OR 3.39 (95%CI 1.82-6.31), p = 0.000] CV risk factors had a higher odds ratio for the presence of high disease activity compared with the zero CV category. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) activity score was significantly associated with the number of CV risk factors, being higher in patients with more CV risk factors. These relationships showed a CV risk factor-dependent effect being beta coefficients and ORs higher for the effect of ?2 over 1 CV risk factor. Conclusion: Among patients with axSpA, as the number of traditional CV risk factors increased, disease activity similarly increases in an independent manner.Funding: The authors disclosed receipt of the following financial support for the research, authorship, and/ or publication of this article: This research was funded by a grant to MAG-G from the Instituto de Salud Carlos III (ISCIII) (Fondo de Investigación Sanitaria grants PI06/0024, PI09/00748, PI12/00060, PI15/00525, PI18/00043) and the ISCIII RETICS programs (RD12/0009 and RD16/0012)

Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project

Introduction: Large variability among Alzheimer's disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways. Methods: Genome Research at Fundacio ACE (GR@ACE) is a genome-wide study of dementia and its clinical endophenotypes, defined based on AD's clinical certainty and vascular burden. We assessed the impact of known AD loci across endophenotypes to generate loci categories. We incorporated gene coexpression data and conducted pathway analysis per category. Finally, to evaluate the effect of heterogeneity in genetic studies, GR@ACE series were meta-analyzed with additional genome-wide association study data sets. Results: We classified known AD loci into three categories, which might reflect the disease clinical heterogeneity. Vascular processes were only detected as a causal mechanism in probable AD. The meta-analysis strategy revealed the ANKRD31-rs4704171 and NDUFAF6-rs10098778 and confirmed SCIMP-rs7225151 and CD33-rs3865444. Discussion: The regulation of vasculature is a prominent causal component of probable AD. GR@ACE meta-analysis revealed novel AD genetic signals, strongly driven by the presence of clinical heterogeneity in the AD series

Experiencias de aprendizaje

Libro de experiencias de aprendizaje del grupo de investigación Giteca y de los semilleros de investigación en la que se visualizan las diferentes experiencias lideradas por instructores y aprendices en las diferentes áreas y líneas de formación.Book of learning experiences of the Giteca research group and the research hotbeds in which the different experiences led by instructors and apprentices in the different areas and lines of training are visualized.Propagación in vitro como un camino de aprendizaje para la formación profesional integral -- Experiencias significativas de aprendizaje, laboratorio de hematología y parasitología animal del Complejo Tecnológico para la Gestión Agroempresarial CTPGA-SENA -- Experiencias significativas adquiridas por aprendices en el área de SENNOVA, Complejo Tecnológico para la Gestión Agroempresarial. Regional – Antioquia -- El papel de la prensa escrita en el desarrollo de la competencia textual -- Aprendiendo a Emprender con un emprendedor -- Ven y te cuento sobre ADSI -- Observaciones fenológicas del cultivo de cacao (Theobroma cacao) en los municipios de Tarazá, El Bagre y Caucasia dentro de la formación del programa SENA emprende rural -- Tejiendo sueños desde la formación -- Forraje verde hidropónico como alternativa para disminuir la expansión de la frontera agrícola en el Putumayo -- La importancia del saber hacer para ser competente en el sector agrícola -- Experiencia significativa de aprendizaje semilleros de investigación -- La investigación como ente transformador de pensamientos -- Piscícola Paraguay; Mi Sueño, Mi Proyecto de Vida! -- Estrategia de aprendizaje a través de la investigación y la empresa aplicando un programa de Responsabilidad Social Empresarial –RSE -- Matemática aplicada para procesos agroindustriales de panificaciónna85 página