Text2Face: 3D Morphable Faces from Text

We present the first 3D morphable modelling approach, whereby 3D face shape can be directly and completely defined using a textual prompt. Building on work in multi-modal learning, we extend the FLAME head model to a common imageand-text latent space. This allows for direct 3D Morphable Model (3DMM) parameter generation and therefore shape manipulation from textual descriptions. Our method, Text2Face, has many applications; for example: generating police photofits where the input is already in natural language. It further enables multimodal 3DMM image fitting to sketches and sculptures, as well as images

Tractarian Objects and Logical Categories

It has been much debated whether Tractarian objects are what Russell would have called particulars or whether they include also properties and relations. This paper claims that the debate is misguided: there is no logical category such that Wittgenstein intended the reader of the Tractatus to understand his objects either as providing examples of or as not providing examples of that category. This is not to say that Wittgenstein set himself against the very idea of a logical category: quite the contrary. However, where Russell presents his logical variety of particulars and the various types of universal, and Frege presents his of objects and the various types of function, Wittgenstein denies the propriety of such a priori expositions. Wittgenstein envisages a variety of logical types of entity but insists that the nature of these types is something to be discovered only through analysis

Applications of 3D Photography in Craniofacial Surgery

Three-dimensional (3D) photography is becoming more common in craniosynostosis practice and may be used for research, archiving, and as a planning tool. In this article, an overview of the uses of 3D photography will be given, including systems available and illustrations of how they can be used. Important innovations in 3D computer vision will also be discussed, including the potential role of statistical shape modeling and analysis as an outcomes tool with presentation of some results and a review of the literature on the topic. Potential future applications in diagnostics using machine learning will also be presented

Late Quaternary evolution of a lowland anastomosing river system: Geological-topographic inheritance, non-uniformity and implications for biodiversity and management

Lowland multiple-channel rivers are characterised by floodplain-corridor heterogeneity, high ecological and heritage value, and can be in quasi-stable states. This holistic study of a surviving temperate zone example (Culm, UK) uses geomorphological mapping, 14C, direct sediment dating (OSL, fallout radionuclides), and palaeoecology. This reveals the evolution of a channel-floodplain system from an initial braided state in the Late Pleistocene to its late Holocene anastomosing state. After the Pleistocene Holocene transition the reduced channel system incised into its braid-plain, only able to rework gravels locally due to reduced competence in relation to inherited bounding sediment calibre. This resulted in the creation of terrace islands, palaeochannels, and a stable anastomosing pattern dominated by channel junctions, bifurcations and palaeochannel intersections. Survey, coring and excavation reveal a persistence of mid-channel bars and riffles at channel junctions, and where channels crossed palaeochannel fills. In common with most other European lowland rivers this system evolves in the later Holocene due to both climate and catchment changes with a major hydrological critical transition in the mid-Holocene (c. 5300 BP). However, in the case of the Culm, the increase in fine sediment supply often seen in lowland catchments in the Middle-Late Holocene, occurred later, and was insufficient to convert the system to a single medium-low sinuosity channel-floodplain. This allowed the persistence of high heterogeneity and biodiversity (including the persistence of riffle beetles) as part of multiple-scales of non-uniformity. Indeed the pool-riffle persistence is an example of this system’s non-uniformity, being due, at least in part, to the effects of previous channel history. This paper reveals why this river survived in a multichannel state, and by implication, why others did not. These results are being used in the bespoke eco-heritage management of the Culm, but could also inform the restoration of other former multi-channel lowland temperate river systems worldwide

Hard and Blind: On Wittgenstein's Genealogical View of Logical Necessity

My main aim is to sketch a certain reading (‘genealogical') of later Wittgenstein's views on logical necessity. Along the way, I engage with the inferentialism currently debated in the literature on the epistemology of deductive logic.publishedVersio

Development of the SIOPE DIPG network, registry and imaging repository : a collaborative effort to optimize research into a rare and lethal disease

Diffuse intrinsic pontine glioma (DIPG) is a rare and deadly childhood malignancy. After 40 years of mostly single-center, often non-randomized trials with variable patient inclusions, there has been no improvement in survival. It is therefore time for international collaboration in DIPG research, to provide new hope for children, parents and medical professionals fighting DIPG. In a first step towards collaboration, in 2011, a network of biologists and clinicians working in the field of DIPG was established within the European Society for Paediatric Oncology (SIOPE) Brain Tumour Group: the SIOPE DIPG Network. By bringing together biomedical professionals and parents as patient representatives, several collaborative DIPG-related projects have been realized. With help from experts in the fields of information technology, and legal advisors, an international, web-based comprehensive database was developed, The SIOPE DIPG Registry and Imaging Repository, to centrally collect data of DIPG patients. As for April 2016, clinical data as well as MR-scans of 694 patients have been entered into the SIOPE DIPG Registry/Imaging Repository. The median progression free survival is 6.0 months (95% Confidence Interval (CI) 5.6-6.4 months) and the median overall survival is 11.0 months (95% CI 10.5-11.5 months). At two and five years post-diagnosis, 10 and 2% of patients are alive, respectively. The establishment of the SIOPE DIPG Network and SIOPE DIPG Registry means a paradigm shift towards collaborative research into DIPG. This is seen as an essential first step towards understanding the disease, improving care and (ultimately) cure for children with DIPG.Peer reviewe

Evidence-based cardiovascular care in the community: A population-based cross-sectional study

BACKGROUND: Ischaemic heart disease and congestive heart failure are common and important conditions in family practice. Effective treatments may be underutilized, particularly in women and the elderly. The objective of the study was to determine the rate of prescribing of evidence-based cardiovascular medications and determine if these differed by patient age or sex. METHODS: We conducted a two-year cross-sectional study involving all hospitals in the province of Nova Scotia, Canada. Subjects were all patients admitted with ischaemic heart disease with or without congestive heart failure between 15 October 1997 and 14 October 1999. The main measure was the previous outpatient use of recommended medications. Chi-square analyses followed by multivariate logistic regression analyses were used to examine age-sex differences. RESULTS: Usage of recommended medications varied from approximately 60% for beta-blockers and angiotensin converting enzyme (ACE) inhibitors to 90% for antihypertensive agents. Patients aged 75 and over were significantly less likely than younger patients to be taking any of the medication classes. Following adjustment for age, there were no significant differences in medication use by sex except among women aged 75 and older who were more likely to be taking beta-blockers than men in the same age group. CONCLUSIONS: The use of evidence-based cardiovascular medications is rising and perhaps approaching reasonable levels for some drug classes. Family physicians should ensure that all eligible patients (prior myocardial infarction, congestive failure) are offered beta-blockers or ACE inhibitors

Global warming and recurrent mass bleaching of corals

During 2015–2016, record temperatures triggered a pan-tropical episode of coral bleaching, the third global-scale event since mass bleaching was first documented in the 1980s. Here we examine how and why the severity of recurrent major bleaching events has varied at multiple scales, using aerial and underwater surveys of Australian reefs combined with satellite-derived sea surface temperatures. The distinctive geographic footprints of recurrent bleaching on the Great Barrier Reef in 1998, 2002 and 2016 were determined by the spatial pattern of sea temperatures in each year. Water quality and fishing pressure had minimal effect on the unprecedented bleaching in 2016, suggesting that local protection of reefs affords little or no resistance to extreme heat. Similarly, past exposure to bleaching in 1998 and 2002 did not lessen the severity of bleaching in 2016. Consequently, immediate global action to curb future warming is essential to secure a future for coral reefs