1,103 research outputs found

    PIH21 EFFICACY OF TREATMENT AND PATIENT SATISFACTION IN TREATMENT OF CLIMACTERIC DISORDERS WITH SOY ISOFLAVONES: FRENCH APPROCH

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    Optical constants of solid methane

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    Methane is the most abundant simple organic molecule in the outer solar system bodies. In addition to being a gaseous constituent of the atmospheres of the Jovian planets and Titan, it is present in the solid form as a constituent of icy surfaces such as those of Triton and Pluto, and as cloud condensate in the atmospheres of Titan, Uranus, and Neptune. It is expected in the liquid form as a constituent of the ocean of Titan. Cometary ices also contain solid methane. The optical constants for both solid and liquid phases of CH4 for a wide temperature range are needed for radiative transfer calculations, for studies of reflection from surfaces, and for modeling of emission in the far infrared and microwave regions. The astronomically important visual to near infrared measurements of solid methane optical constants are conspicuously absent from the literature. Preliminary results are presented on the optical constants of solid methane for the 0.4 to 2.6 micrometer region. Deposition onto a substrate at 10 K produces glassy (semi-amorphous) material. Annealing this material at approximately 33 K for approximately 1 hour results in a crystalline material as seen by sharper, more structured bands and negligible background extinction due to scattering. The constant k is reported for both the amorphous and the crystalline (annealed) states. Typical values (at absorption maxima) are in the .001 to .0001 range. Below lambda = 1.1 micrometers the bands are too weak to be detected by transmission through the films less than or equal to 215 micrometers in thickness, employed in the studies to date. Using previously measured values of the real part of the refractive index, n, of liquid methane at 110 K, n is computed for solid methane using the Lorentz-Lorenz relationship. Work is in progress to extend the measurements of optical constants n and k for liquid and solid to both shorter and longer wavelengths, eventually providing a complete optical constants database for condensed CH4

    A STEADY PSEUDO-COMPRESSIBILITY APPROACH BASED ON UNSTRUCTURED HYBRID FINITE VOLUME TECHNIQUES APPLIED TO TURBULENT PREMIXED FLAME PROPAGATION

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    A pseudo-compressibility method for zero Mach number turbulent reactive flows with heat release is combined with an unstructured finite volume hybrid grid scheme. The spatial discretization is based on an overlapped cell vertex approach. An infinite freely planar flame propagating into a turbulent medium of premixed reactants is considered as a test case. The recourse to a flamelet combustion modeling for which the reaction rate is quenched in a continuous way ensures the uniqueness of the turbulent flame propagation velocity. To integrate the final form of discretized governing equations, a three-stage hybrid time-stepping scheme is used and artificial dissipation terms are added to stabilize the convergence path towards the final steady solution. The results obtained with such a numerical procedure prove to be in good agreement with those reported in the literature on the very same flow geometry. Indeed, the flame structure as well as its propagation velocity are accurately predicted thus confirming the validity of the approach followed and demonstrating that such a numerical procedure will be a valuable tool to deal with complex reactive flow geometries

    Fermi Large Area Telescope Fourth Source Catalog Data Release 4 (4FGL-DR4)

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    We present an incremental version (4FGL-DR4, for Data Release 4) of the fourth Fermi-LAT catalog of gamma-ray sources. Based on the first 14 years of science data in the energy range from 50 MeV to 1 TeV, it uses the same analysis methods as the 4FGL-DR3 catalog did for 12 years of data, with only a few improvements. The spectral parameters, spectral energy distributions, light curves and associations are updated for all sources. We add four new extended sources and modify two existing ones. Among the 6658 4FGL-DR3 sources, we delete 14 and change the localization of 10, while 26 are newly associated and two associations were changed. We add 546 point sources, among which 8 are considered identified and 228 have a plausible counterpart at other wavelengths. Most are just above the detection threshold, and 14 are transient sources below the detection threshold that can affect the light curves of nearby sources.Comment: Data files at https://fermi.gsfc.nasa.gov/ssc/data/access/lat/14yr_catalog/. Refereed paper is DOI 10.3847/1538-4365/ac675

    Is the Black-widow Pulsar PSR J1555-2908 in a Hierarchical Triple System?

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    The 559 Hz black-widow pulsar PSR J1555-2908, originally discovered in radio, is also a bright gamma-ray pulsar. Timing its pulsations using 12 yr of Fermi-Large Area Telescope gamma-ray data reveals long-term variations in its spin frequency that are much larger than is observed from other millisecond pulsars. While this variability in the pulsar rotation rate could be intrinsic "timing noise,"here we consider an alternative explanation: the variations arise from the presence of a very-low-mass third object in a wide multiyear orbit around the neutron star and its low-mass companion. With current data, this hierarchical-triple-system model describes the pulsar's rotation slightly more accurately than the best-fitting timing noise model. Future observations will show if this alternative explanation is correct. © 2022. The Author(s). Published by the American Astronomical Society

    Measurement of 1.7 to 74 MeV polarised gamma rays with the HARPO TPC

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    Current {\gamma}-ray telescopes based on photon conversions to electron-positron pairs, such as Fermi, use tungsten converters. They suffer of limited angular resolution at low energies, and their sensitivity drops below 1 GeV. The low multiple scattering in a gaseous detector gives access to higher angular resolution in the MeV-GeV range, and to the linear polarisation of the photons through the azimuthal angle of the electron-positron pair. HARPO is an R&D program to characterise the operation of a TPC (Time Projection Chamber) as a high angular-resolution and sensitivity telescope and polarimeter for {\gamma} rays from cosmic sources. It represents a first step towards a future space instrument. A 30 cm cubic TPC demonstrator was built, and filled with 2 bar argon-based gas. It was put in a polarised {\gamma}-ray beam at the NewSUBARU accelerator in Japan in November 2014. Data were taken at different photon energies from 1.7 MeV to 74 MeV, and with different polarisation configurations. The electronics setup is described, with an emphasis on the trigger system. The event reconstruction algorithm is quickly described, and preliminary measurements of the polarisation of 11 MeVphotons are shown.Comment: Proceedings VCI201

    Should all acutely ill children in primary care be tested with point-of-care CRP: A cluster randomised trial

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    Background: Point-of-care blood C-reactive protein (CRP) testing has diagnostic value in helping clinicians rule out the possibility of serious infection. We investigated whether it should be offered to all acutely ill children in primary care or restricted to those identified as at risk on clinical assessment. Methods: Cluster randomised controlled trial involving acutely ill children presenting to 133 general practitioners (GPs) at 78 GP practices in Belgium. Practices were randomised to undertake point-of-care CRP testing in all children (1730 episodes) or restricted to children identified as at clinical risk (1417 episodes). Clinical risk was assessed by a validated clinical decision rule (presence of one of breathlessness, temperature ≥ 40 °C, diarrhoea and age 12-30 months, or clinician concern). The main trial outcome was hospital admission with serious infection within 5 days. No specific guidance was given to GPs on interpreting CRP levels but diagnostic performance is reported at 5, 20, 80 and 200 mg/L. Results: Restricting CRP testing to those identified as at clinical risk substantially reduced the number of children tested by 79.9 % (95 % CI, 77.8-82.0 %). There was no significant difference between arms in the number of children with serious infection who were referred to hospital immediately (0.16 % vs. 0.14 %, P = 0.88). Only one child with a CRP < 5 mg/L had an illness requiring admission (a child with viral gastroenteritis admitted for rehydration). However, of the 80 children referred to hospital to rule out serious infection, 24 (30.7 %, 95 % CI, 19.6-45.6 %) had a CRP < 5 mg/L. Conclusions: CRP testing should be restricted to children at higher risk after clinical assessment. A CRP < 5 mg/L rules out serious infection and could be used by GPs to avoid unnecessary hospital referrals

    Inference of proto-neutron star properties in core-collapse supernovae from a gravitational-wave detector network

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    The next Galactic core-collapse supernova (CCSN) will be a unique opportunity to study within a fully multi-messenger approach the explosion mechanism responsible for the formation of neutron stars and stellar-mass black holes. State-of-the-art numerical simulations of those events reveal the complexity of the gravitational-wave emission which is highly stochastic. This challenges the possibility to infer the properties of the compact remnant and of its progenitor using the information encoded in the waveforms. In this paper we take further steps in a program we recently initiated to overcome those difficulties. In particular we show how oscillation modes of the proto-neutron star, highly visible in the gravitational-wave signal, can be used to reconstruct the time evolution of their physical properties. Extending our previous work where only the information from a single detector was used we here describe a new data-analysis pipeline that coherently combines gravitational-wave detectors' data and infers the time evolution of a combination of the mass and radius of the compact remnant. The performance of the method is estimated employing waveforms from 2D and 3D CCSN simulations covering a progenitor mass range between 11M⊙\mathrm{M_{\odot}}\, and 40M⊙\mathrm{M_{\odot}}\, and different equations of state for both a network of up to five second-generation detectors and the proposed third-generation detectors Einstein Telescope and Cosmic Explorer. Our study shows that it will be possible to infer PNS properties for CCSN events occurring in the vicinity of the Milky Way, up to the Large Magellanic Cloud, with the current generation of gravitational-wave detectors

    Discovery, Timing, and Multiwavelength Observations of the Black Widow Millisecond Pulsar PSR J1555-2908

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    We report the discovery of PSR J1555-2908, a 1.79 ms radio and gamma-ray pulsar in a 5.6 hr binary system with a minimum companion mass of 0.052 M⊙M_\odot. This fast and energetic (E˙=3×1035\dot E = 3 \times 10^{35} erg/s) millisecond pulsar was first detected as a gamma-ray point source in Fermi LAT sky survey observations. Guided by a steep spectrum radio point source in the Fermi error region, we performed a search at 820 MHz with the Green Bank Telescope that first discovered the pulsations. The initial radio pulse timing observations provided enough information to seed a search for gamma-ray pulsations in the LAT data, from which we derive a timing solution valid for the full Fermi mission. In addition to the radio and gamma-ray pulsation discovery and timing, we searched for X-ray pulsations using NICER but no significant pulsations were detected. We also obtained time-series r-band photometry that indicates strong heating of the companion star by the pulsar wind. Material blown off the heated companion eclipses the 820 MHz radio pulse during inferior conjunction of the companion for ~10% of the orbit, which is twice the angle subtended by its Roche lobe in an edge-on system
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