Controllable quantum scars in semiconductor quantum dots

Quantum scars are enhancements of quantum probability density along classical periodic orbits. We study the recently discovered phenomenon of strong, perturbation-induced quantum scarring in the two-dimensional harmonic oscillator exposed to a homogeneous magnetic field. We demonstrate that both the geometry and the orientation of the scars are fully controllable with a magnetic field and a focused perturbative potential, respectively. These properties may open a path into an experimental scheme to manipulate electric currents in nanostructures fabricated in a two-dimensional electron gas.Comment: 5 pages, 4 figure

Kun tilaa on vähän:tutkielma pienten asuntojen muunneltavuuden ja monikäyttöisyyden lisäämisestä joustavan suunnittelun keinoin esteettömyysohjeita luovasti soveltaen

Tiivistelmä. Tutkin diplomityössäni rakenteilla olevia pieniä kerrostaloasuntoja ja niiden joustavuuden toteutumista. Tutkin aihetta esteettömyysmääräysten ja -ohjeiden luovan soveltamisen sekä joustavan asunnon suunnittelun keinojen ja tilallisten logiikoiden avulla. Diplomityöni jakautuu kahteen osioon, kirjalliseen teoriaosuuteen ja suunnitelmaosuuteen. Kirjallisessa teoriaosassa pohjustan tutkielmani rajaukseen johtaneen idean, joka liittyy tutkimusten sekä arkkitehtijulkaisujen kritiikkiin pienenevästä ja joustamattomasta uudisasuntotuotannosta. Teoriaosuudessa taustoitan syitä pienten asuntojen suunnittelun taustalla, sekä pohdin olemassa olevan uudisasuntokannan tulevaisuuden näkymiä kirjallisuuskatsauksen avulla. Työni rajautuu tutkimaan pieniä asuntoja esteettömyyden ja joustavuuden näkökulmista. Kirjallisessa osuudessa esittelen uudisasuntosuunnitteluun vaikuttavia esteettömyysmääräyksiä ja -ohjeita, sekä käsittelen omassa luvussa joustavuutta yleisesti ja sen roolia suomalaisessa asuntosuunnittelussa. Lukujen avulla pyrin ymmärtämään esteettömyysmääräysten ja -ohjeiden, sekä joustavuuden toteutumisen suhdetta pienten asuintilojen muodostumisessa ja alustamaan teoriapohjaa aiheista suunnitelmaosuutta varten. Työni suunnitelmaosuudessa tutkin rakenteilla olevien pienten kerrostaloasuntojen joustavuuden lisäämisen mahdollisuuksia tutkittuja joustavuuden keinoja ja logiikoita hyödyntämällä, sekä esteettömyysmääräyksiä ja -ohjeita luovasti soveltamalla. Suunnitelmaosuus jakautuu kolmeen osaan. Ensin analysoin kohdekohtaisesti viittä case-asuntoa pohjapiirustusten avulla laadullisin kriteerein. Tarkasteluaineistona olevat case-asuntopohjat valikoin kolmen suurimman rakennusliikkeen Tampereella rakenteilla olevista yksiö- ja kaksiopohjista. Analysoin pohjapiirustuksissa tilakohtaisia mitoitusperiaatteita ja asuntojen joustavuuden mahdollisuuksia. Toisessa ja kolmannessa osassa suunnitelmaosuutta esitän jokaisesta case-asuntopohjasta kaksi vaihtoehtoista pohjaratkaisua, joissa hyödynnän työni teoriaosuudessa esiteltyjä joustavan asunnon tilallisia logiikoita ja muunneltavia suunnitteluratkaisuja, sekä sovellan luovasti esteettömyysmääräyksiä ja -ohjeita. Case-pohjapiirustusten analyyseissä havaitsin, että ne vastasivat suurimmilta osin työni teoriaosuuden alussa kritisoituja, muodonannoltaan ja tilahierarkialtaan monotonisia kerrostaloasuntoja. Asuntopohjien tilajärjestyksestä oli tunnistettavissa esteettömyysmääräysten ja -ohjeiden ehdoin muodostetut ja standardoidut pienen asunnon tilaratkaisut, jotka ehdollistivat kapean tilan järjestäytymisen niiden mukaan. Pienten asuntojen tilaa hallitsi joustavan ja esteettömän käytön mahdollistava avotila, johon suurin osa asunnon toiminnoista sijoittui. Avotilan rajattu koko kuitenkin heikensi useissa case-pohjapiirustuksissa mahdollisuuksia hyödyntää tiloja vaihtelevin tavoin. Vaihtoehtoisten pohjapiirustusten suunnitelmista totesin, että pieniin asuntoihin voitiin luoda joustavuutta eri mittakaavoissa tiloja suhteellisten keveiden ja joustavuutta tuottavien suunnitteluratkaisujen avulla, sekä asuntojen tiloja kokonaan uudelleen järjestämällä. Vaikka pienissä ja haastavan muotoisissa vaihtoehtoisissa pohjapiirustuksissakaan ei synny kaiken kattavaa joustavuutta, vaihtoehtoisia tilaratkaisuja samaan asuntopohjaan esittämällä, asuntojen mitoitusta luovasti tarkastelemalla sekä erilaisia käyttömahdollisuuksia tarjoamalla voidaan lisätä asukkaiden vaikuttamismahdollisuuksia ja näin ollen mahdollisesti lisätä asuntojen houkuttelevuutta myös tulevaisuudessa. Esteettömyysmääräysten ja -ohjeiden luova soveltaminen jäi vaihtoehtoisissa pohjapiirustuksissa vähäiseksi. Määräysten ja -ohjeiden luovan soveltamisen sijaan asunnon esteettömiä tiloja ja toimintoja tulisi suunnitella asunnon muodon ehdoin yhdessä joustavuutta tuottavien suunnitteluratkaisujen kanssa

Faculty Perceptions of the Value of Academic Libraries: A Mixed Method Study

This article details the findings of a year-long study at Indiana University of Pennsylvania (IUP) Libraries which examined IUP faculty members’ perceptions of the value of library resources and services to both their research and teaching. Through a mixed-method study, which included an online survey and follow-up focus groups, the researchers found that faculty were dissatisfied with IUP Libraries’ marketing initiatives but satisfied with its small embedded librarian program. As a result, marketing and growth of the embedded librarian program became the two main focus areas for improvement in the next academic year

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

Correction: Volume: 23 Issue: 9 DOI: 10.1038/mp.2017.202 Published: SEP 2018Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously low body weight, and a deep and persistent fear of gaining weight. To date, only one genome-wide significant locus associated with AN has been identified. We performed an exome-chip based genome-wide association studies (GWAS) in 2158 cases from nine populations of European origin and 15 485 ancestrally matched controls. Unlike previous studies, this GWAS also probed association in low-frequency and rare variants. Sixteen independent variants were taken forward for in silico and de novo replication (11 common and 5 rare). No findings reached genome-wide significance. Two notable common variants were identified: rs10791286, an intronic variant in OPCML (P = 9.89 x 10(-6)), and rs7700147, an intergenic variant (P = 2.93 x 10(-5)). No low-frequency variant associations were identified at genome-wide significance, although the study was well-powered to detect low-frequency variants with large effect sizes, suggesting that there may be no AN loci in this genomic search space with large effect sizes.Peer reviewe

Complete Atrioventricular Septal Defect : Evolution of Results in a Single Center During 50 Years

Background. Operative mortality after complete atrioventricular septal defect (cAVSD) repair has improved vastly. Less improvement has been demonstrated regarding late mortality and reoperation rates, however. There is evident lack of comprehensive population-based studies analyzing the history and progress of the ever-changing operative results. Methods. This is a 5-million population-based retrospective study of consecutive 388 cAVSD patients operated in Finland between 1962 and 2014. Data were collected using Children's Cardiac Surgical Registry of Children's Hospital at the Helsinki University Hospital, Finland. Mortality data and reoperation rates were analyzed on a decade-by-decade basis. Results. During the early era, overall mortality was 17.4%, operative mortality constituting 10.9%. The operative results have improved significantly over the decades, and eventually, the last decade showed no mortality. A total of 23 late deaths occurred; of these, 20 were directly heart-related. Half of the late mortality occurred during the first postoperative year. The only significant risk factor for overall mortality was an earlier decade of operation (p <0.001). Reoperation rates have not decreased but slightly increased over decades (p = 0.621), and reoperations have been performed mainly during the first year after the primary operation. Actuarial freedom from left side atrioventricular valve reoperation at 15 years was 90.9%. Conclusions. There has been an outstanding improvement in surgical results through the years even though the general operative approach has remained the same. Rates of reoperation have not been declining, but the reoperations are dated to early childhood years. The improvement in results has been ongoing. (C) 2019 by The Society of Thoracic SurgeonsPeer reviewe

Relativistic theory of magnetic scattering of x rays: Application to ferromagnetic iron

We present a detailed description of a first-principles formalism for magnetic scattering of circularly polar- ized x rays from solids in the framework of the fully relativistic spin-polarized multiple-scattering theory. The scattering amplitudes are calculated using a standard time-dependent perturbation theory to second order in the electron-photon interaction vertex. Particular attention is paid to understanding the relative importance of the positive- and negative-energy solutions of the Dirac equation to the scattering amplitude. The advantage of the present theory as compared with other recent works on magnetic x-ray scattering is that, being fully relativistic, spin-orbit coupling and spin-polarization effects are treated on an equal footing. Second, the electron Green’s function expressed in terms of the path operators in the multiple-scattering theory allows us to include the contribution of the crystalline environment to the scattering amplitude. To illustrate the use of the method we have done calculations on the anomalous magnetic scattering at the K , L_II , and L_III absorption edges of ferromagnetic iron

Validirane RP-RP-HPLC i TLC metode za simultano određivanje tamsulozin hidroklorida i finasterida u istom dozirnom pripravku

Reversed phase high-performance liquid chromatography (RP-HPLC) and thin-layer chromatography (TLC) methods have been developed and validated for simultaneous estimation of tamsulosin hydrochloride and finasteride in bulk drug and in combined dosage forms. RP-HPLC separation was achieved on a Phenomenex C18 column using methanol/0.02 mol L-1 ammonium acetate buffer/triethylamine (79.9 + 20 + 0.1, V/V/V) (pH 9.2) as mobile phase. The TLC separation was achieved on an aluminium-backed layer of silica gel 60F254 using toluene/methanol/triethylamine (9 + 1.5 + 1, V/V/V) as eluent. Quantification was achieved with photodiode array (PDA) detection at 235 nm over the concentration range 0.5–16 and 150 µg mL1 with mean recovery of 99.8 ± 0.9 and 100.0 ± 0.8 % for tamsulosin hydrochloride and finasteride, respectively, by the RP-HPLC method. Quantification was achieved with UV detection at 270 nm over the concentration range 100–2000 ng per spot and 250–5000 ng per spot with mean recovery of 98.9 ± 0.9 and 99.6 ± 0.7 % for tamsulosin hydrochloride and finasteride, respectively, by the TLC method. Both methods are simple, precise, accurate and sensitive and are applicable to the simultaneous determination of tamsulosin hydrochloride and finasteride in bulk drug and in combined dosage forms.U radu su opisani razvoj i validacija inverzno fazne kromatografije visoke učinkovitosti (RP-HPLC) i tankoslojne kromatografije (TLC) za simultano određivanje tamsulozin hidroklorida i finasterida kao čistih supstancija i u kombiniranim tabletama. Za RP-HPLC odjeljivanje korištena je Phenomenex C18 kolona (250 mm, 4,6 mm, 5 µm) i metanol/0,02 mol L–1 pufer s amonijevim acetatom/trietilamin (79,9+20+0,1, V/V/V) (pH 9,2) kao pokretna faza, pri protoku 1 mL min-1. TLC odjeljivanje rađeno je na silikagelu 60F254 na aluminijskoj podlozi, koristeći toluen/metanol/trietilamin (9+1,5+1, V/V/V) kao eluens. Za detekciju u RP-HPLC metodi korištena je fotodioda (PDA) pri 235 nm te je provedena kvantitacija u koncentracijskom području 0,5–16 µg mL–1 i 1–50 µg mL–1, uz srednji analitički povrat od 99,8 ± 0,9 % za tamsulozin hidroklorid i 100,0 ± 0,8 % za finasterid. Za kvantitaciju u TLC metodi korištena je UV detekcija pri 270 nm u koncentracijskom području 100–2000 ng po točki za tamsulozin hidroklorid i 250–5000 ng po točki za finasterid, uz srednji analitički povrat od 98,9 ± 0,9, odnosno 99,6 ± 0,7 %. Obje metode su jednostavne, precizne, točne i osjetljive i mogu se primijeniti za simultano određivanje tamsulozin hidroklorida i finasterida kao čistih supstancija i u kombiniranim dozirnim oblicima

Deconvolving Instrumental and Intrinsic Broadening in Excited State X-ray Spectroscopies

Intrinsic and experimental mechanisms frequently lead to broadening of spectral features in excited-state spectroscopies. For example, intrinsic broadening occurs in x-ray absorption spectroscopy (XAS) measurements of heavy elements where the core-hole lifetime is very short. On the other hand, nonresonant x-ray Raman scattering (XRS) and other energy loss measurements are more limited by instrumental resolution. Here, we demonstrate that the Richardson-Lucy (RL) iterative algorithm provides a robust method for deconvolving instrumental and intrinsic resolutions from typical XAS and XRS data. For the K-edge XAS of Ag, we find nearly complete removal of ~9.3 eV FWHM broadening from the combined effects of the short core-hole lifetime and instrumental resolution. We are also able to remove nearly all instrumental broadening in an XRS measurement of diamond, with the resulting improved spectrum comparing favorably with prior soft x-ray XAS measurements. We present a practical methodology for implementing the RL algorithm to these problems, emphasizing the importance of testing for stability of the deconvolution process against noise amplification, perturbations in the initial spectra, and uncertainties in the core-hole lifetime.Comment: 35 pages, 13 figure

The L1TD1 Protein Interactome Reveals the Importance of Post-transcriptional Regulation in Human Pluripotency

Peer reviewe

Electronic structure investigation of CoO by means of soft X-ray scattering

The electronic structure of CoO is studied by resonant inelastic soft X-ray scattering spectroscopy using photon energies across the Co 2p absorption edges. The different spectral contributions from the energy-loss structures are identified as Raman scattering due to d-d and charge-transfer excitations. For excitation energies close to the L3 resonance, the spectral features are dominated by quartet-quartet and quartet-doublet transitions of the 3d7 configuration. At excitation energies corresponding to the satellites in the Co 2p X-ray absorption spectrum of CoO, the emission features are instead dominated by charge-transfer transitions to the 3d8L-1 final state. The spectra are interpreted and discussed with the support of simulations within the single impurity Anderson model with full multiplet effects which are found to yield consistent spectral functions to the experimental data.Comment: 8 pages, 2 figures, 2 tables, http://link.aps.org/doi/10.1103/PhysRevB.65.20510