Lesiones esqueléticas asociadas al síndrome de Papillon-Lefèvre

Se presentan dos casos de Síndrome de Papillon-Lefèvre que se asocian a osteolisis espontánea de los metatarsianos y las falanges de los dedos de los pies. Esta asociación no había sido descrita con anterioridad.Two case s of Papillon-Lefèvre syndrome associated with spontaneous osteolysis of the phalanges and metatarsals of the toe s are presented. This association has not been previously reported

Confección de claves de identificación para los parques urbanos de Melilla. Un recurso didáctico

En el marco de un proyecto de innovación docente, desarrollado en la Facultad de Educación de Melilla, se están confeccionando materiales didácticos para el ciclo superior de Educación Primaria, entre ellos claves botánicas cientifico-didácticas para los parques de la ciudad de Melilla. En este trabajo se describe el proceso de diseño y elaboración, así como su implementación en varios colegios, tanto en salidas de campo como en la versión virtual, poniéndose de manifiesto el alto valor didáctico de estos documentos que favorecen el acercamiento del niño al trabajo del científico. La botánica, en este caso, se convierte en un recurso valioso para abordar objetivos y competencias preconizados en la legislación para diferentes áreas, especialmente Conocimiento del Medio y las instrumentales de Lengua y Matemáticas

Luxación traumática bilateral de cadera

Se presenta un caso de luxación bilateral simultánea de caderas, una anterior y otra posterior, asociada a fractura del acetábulo derecho, fractura de la diáfisis femoral derecha y una subluxación del raquis cervical.A case of simultaneous bilateral anterior and posterior dislocation of the hip joints associated with a fracture of the right acetabulum and right femoral shaft, and a subluxation of the cervical spine, is reported

Las controversias en el aula : ¿alfabetización científico-tecnológica o alfabetización socio-tecnológica?

El presente trabajo se dirige hacia el tratamiento en el aula de controversias socio-tecnológicas. No está claro que tipo de información científica deben conocer los ciudadanos para poseer opiniones fundamentadas hacia los casos controvertidos y cual es la información que debe movilizarse en el desarrollo de los debates sobre las controversias. Tras un estudio diagnóstico sobre dos innovaciones biotecnológicas (alimentos transgénicos y bacterias modificadas genéticamente), se concluye que la percepción es diferente en cada caso aunque ambos poseen el mismo origen, la ingeniería genética, y se constata la necesidad de una alfabetización socio-tecnológica, que integre la información científica y tecnológica con la de tipo social, económico y político, para defender posiciones fundamentadas

Short-term effect of heat waves on hospital admissions in Madrid: Analysis by gender and comparision with previous findings

Global warming affects health through multiple exposures and pathways, in and is turn deeply influenced by climate change. Every year, several million deaths are caused by environmental factors, many of which are aggravated by climate change or its drivers (WHO, 2016). The adverse effects of climate change on health are varied, complex and far-reaching. Essentially, climate change acts as a multiplier for global health threats, compounding many of the health issues communities already face. Disproportionately affect the health of vulnerable groups and people in lower income countries, thus exacerbating inequalities and gender differences (Watts et al., 2018)

Carotenoid Cleavage Oxygenases from Microbes and Photosynthetic Organisms: Features and Functions

Apocarotenoids are carotenoid-derived compounds widespread in all major taxonomic groups, where they play important roles in different physiological processes. In addition, apocarotenoids include compounds with high economic value in food and cosmetics industries. Apocarotenoid biosynthesis starts with the action of carotenoid cleavage dioxygenases (CCDs), a family of non-heme iron enzymes that catalyze the oxidative cleavage of carbon–carbon double bonds in carotenoid backbones through a similar molecular mechanism, generating aldehyde or ketone groups in the cleaving ends. From the identification of the first CCD enzyme in plants, an increasing number of CCDs have been identified in many other species, including microorganisms, proving to be a ubiquitously distributed and evolutionarily conserved enzymatic family. This review focuses on CCDs from plants, algae, fungi, and bacteria, describing recent progress in their functions and regulatory mechanisms in relation to the different roles played by the apocarotenoids in these organisms.Ministerio de Ciencia y Tecnología AGL2015-70218, BIO2013-44239-R, AGL2012-34573, BIO2012-39716 y BIO2009-11131Junta de Andalucía P07-CVI-02813 y CTS-6638Generalitat Valenciana PROMETEOII/2014/02

Review of the book “Extreme Temperatures and Health: How Heat Waves and Cold Snaps Affect Us”

Not available

Revisão do livro “Temperaturas extremas e saúde. Como nos afetam as ondas de calor e de frio”

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Mortality attributable to extreme temperatures in Spain: A comparative analysis by city

BACKGROUND: The Low Temperature Days (LTD) have attracted far less attention than that of High Temperature Days (HTD), though its impact on mortality is at least comparable. This lower degree of attention may perhaps be due to the fact that its influence on mortality is less pronounced and longer-term, and that there are other concomitant infectious winters factors. In a climate-change scenario, the studies undertaken to date report differing results. The aim of this study was to analyse mortality attributable to both thermal extremes in Spain's 52 provinces across the period 2000-2009, and estimate the related economic cost to show the benefit or "profitability" of implementing prevention plans against LTD. METHODS: Previous studies enabled us: to obtain the maximum daily temperature above which HTD occurred and the minimum daily temperature below which LTD occurred in the 52 provincial capitals analysed across the same study period; and to calculate the relative and attributable risks (%) associated with daily mortality in each capital. These measures of association were then used to make different calculations to obtain the daily mean mortality attributable to both thermal extremes. To this end, we obtained a summary of the number of degrees whereby the temperature exceeded (excess °C) or fell short (deficit °C) of the threshold temperature for each capital, and calculated the respective number of extreme temperatures days. The economic estimates rated the prevention plans as being 68% effective. RESULTS: Over the period considered, the number of HTD (4373) was higher than the number of LTD (3006) for Spain as a whole. Notwithstanding this, in every provincial capital the mean daily mortality attributable to heat was lower (3deaths/day) than that attributable to cold (3.48deaths/day). In terms of the economic impact of the activation of prevention plans against LTD, these could be assumed to avoid 2.37 deaths on each LTD, which translated as a saving of €0.29M. Similarly, in the case of heat, 2.04 deaths could be assumed to be avoided each day on which the prevention plan against HTD was activated, amounting to a saving of €0.25M. While the economic cost of cold-related mortality across the ten-year period 2000-2009 was €871.7M, that attributable to heat could be put at €1093.2M. CONCLUSION: The effect of extreme temperatures on daily mortality was similar across the study period for Spain overall. The lower number of days with LTD meant, however, that daily cold-related mortality was higher than daily heat-related mortality, thereby making prevention plans against LTD more "profitable" prevention plans against HTD in terms of avoidable mortality.This study was supported by grants FIS ENPY 1001/13 & SEPY 1037/14 from Spain's Health Research Fund.S