An equatorial ultra iron-poor star identified in BOSS

We report the discovery of SDSS J131326.89-001941.4, an ultra iron-poor red giant star ([Fe/H] ~ -4.3) with a very high carbon abundance ([C/Fe]~ +2.5). This object is the fifth star in this rare class, and the combination of a fairly low effective temperature (Teff ~ 5300 K), which enhances line absorption, with its brightness (g=16.9), makes it possible to measure the abundances of calcium, carbon and iron using a low-resolution spectrum from the Sloan Digital Sky Survey. We examine the carbon and iron abundance ratios in this star and other similar objects in the light of predicted yields from metal-free massive stars, and conclude that they are consistent. By way of comparison, stars with similarly low iron abundances but lower carbon-to-iron ratios deviate from the theoretical predictions.Comment: 6 pages, 4 figures, accepted for publication in A&

Abundance Analysis of Planetary Host Stars I. Differential Iron Abundances

We present atmospheric parameters and iron abundances derived from high-resolution spectra for three samples of dwarf stars: stars which are known to host close-in giant planets (CGP), stars for which radial velocity data exclude the presence of a close-in giant planetary companion (no-CGP), as well as a random sample of dwarfs with a spectral type and magnitude distribution similar to that of the planetary host stars (control). All stars have been observed with the same instrument and have been analyzed using the same model atmospheres, atomic data and equivalent width modeling program. Abundances have been derived differentially to the Sun, using a solar spectrum obtained with Callisto as the reflector with the same instrumentation. We find that the iron abundances of CGP dwarfs are on average by 0.22 dex greater than that of no-CGP dwarfs. The iron abundance distributions of both the CGP and no-CGP dwarfs are different than that of the control dwarfs, while the combined iron abundances have a distribution which is very similar to that of the control dwarfs. All four samples (CGP, no-CGP, combined, control) have different effective temperature distributions. We show that metal enrichment occurs only for CGP dwarfs with temperatures just below solar and approximately 300 K higher than solar, whereas the abundance difference is insignificant at Teff around 6000 K.Comment: 52 pages (aastex 11pt, preprint style), including 17 figures and 13 tables; accepted for publication in AJ (scheduled for the October 2003 issue

Abundances of Stars with Planets: Trends with Condensation Temperature

Precise abundances of 18 elements have been derived for ten stars known to host giant planets from high signal-to-noise ratio, high-resolution echelle spectroscopy. Internal uncertainties in the derived abundances are typically <=0.05 dex. The stars in our sample have all been previously shown to have abundances that correlate with the condensation temperature (T_c) of the elements in the sense of increasing abundances with increasing T_c; these trends have been interpreted as evidence that the stars may have accreted H-depleted planetary material. Our newly derived abundances also correlate positively with T_c, although slopes of linear least-square fits to the [m/H]-T_c relations for all but two stars are smaller here than in previous studies. When considering the refractory elements (T_c > 900 K) only, which may be more sensitive to planet formation processes, the sample can be separated into a group with positive slopes (four stars) and a group with flat or negative slopes (six stars). The four stars with positive slopes have very close-in giant planets (three at 0.05 AU) and slopes that fall above the general Galactic chemical evolution trend. We suggest that these stars have accreted refractory-rich planet material but not to the extent that would increase significantly the overall stellar metallicity. The flat or negative slopes of the remaining six stars are consistent with recent suggestions of a planet formation signature, although we show that the trends may be the result of Galactic chemical evolution.Comment: 64 pages (single column), 5 figures, 10 tables. Accepted by Ap

Beryllium abundances in stars hosting giant planets

We have derived beryllium abundances in a wide sample of stars hosting planets, with spectral types in the range F7V-K0V, aimed at studying in detail the effects of the presence of planets on the structure and evolution of the associated stars. Predictions from current models are compared with the derived abundances and suggestions are provided to explain the observed inconsistencies. We show that while still not clear, the results suggest that theoretical models may have to be revised for stars with Teff<5500K. On the other hand, a comparison between planet host and non-planet host stars shows no clear difference between both populations. Although preliminary, this result favors a ``primordial'' origin for the metallicity ``excess'' observed for the planetary host stars. Under this assumption, i.e. that there would be no differences between stars with and without giant planets, the light element depletion pattern of our sample of stars may also be used to further investigate and constraint Li and Be depletion mechanisms.Comment: A&A in press -- accepted on the 22/02/2002 (11 pages, 6 figures included

Application of a split-Cre system for high-capacity adenoviral vector amplification

Background and aims: High-capacity adenoviral vectors (HC-AdV) show extended DNA payload and stability of gene expression in vivo due to the absence of viral coding sequences. However, production requires methods to trans-complement viral proteins, usually through Helper Viruses (HV). The Cre/loxP system is frequently employed to remove the packaging signal in HV genomes, in order to avoid their encapsidation. However, chronic exposure to the Cre recombinase in packaging cells is detrimental. We have applied the dimerizable Cre system to overcome this limitation. Methods and results: Cre was split in two fragments devoid of recombinase function (N-terminal 244 and C-terminal 99 amino-acids). In one version of the system, interaction with both moieties was favored by rapamycin-dependent heterodimerization domains (DiCre). Other version contained only Cre sequences (oCre). We generated packaging cells and HVs expressing the complementary fragments and studied their performance for HC-AdV production. We found that both conformations avoided interference with the growth of packaging cells, and the oCre system was particularly suitable for HC-AdV amplification. Conclusions: The split-Cre system improves the performance of packaging cells and can reduce the time and cost of HC-AdV amplification up to 30% and 15%, respectively. This may contribute to the standardization of HC-AdV production

Beryllium anomalies in solar-type field stars

We present a study of beryllium (Be) abundances in a large sample of field solar-type dwarfs and sub-giants spanning a large range of effective temperatures. The analysis shows that Be is severely depleted for F stars, as expected by the light-element depletion models. However, we also show that Beryllium abundances decrease with decreasing temperature for stars cooler than $\sim$6000 K, a result that cannot be explained by current theoretical models including rotational mixing, but that is, at least in part, expected from the models that take into account internal wave physics. In particular, the light element abundances of the coolest and youngest stars in our sample suggest that Be, as well as lithium (Li), has already been burned early during their evolution. Furthermore, we find strong evidence for the existence of a Be-gap for solar-temperature stars. The analysis of Li and Be abundances in the sub-giants of our sample also shows the presence of one case that has still detectable amounts of Li, while Be is severely depleted. Finally, we compare the derived Be abundances with Li abundances derived using the same set of stellar parameters. This gives us the possibility to explore the temperatures for which the onset of Li and Be depletion occurs.Comment: 16 pages, 13 figures, accepted for publication in Astronomy & Astrophysic

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Cancer Signaling networks and Molecular Therapeutic

A Planet at 5 AU Around 55 Cancri

We report precise Doppler shift measurements of 55 Cancri (G8V) obtained from 1989 to 2002 at Lick Observatory. The velocities reveal evidence for an outer planetary companion to 55 Cancri orbiting at 5.5 AU. The velocities also confirm a second, inner planet at 0.11 AU. The outer planet is the first extrasolar planet found that orbits near or beyond the orbit of Jupiter. It was drawn from a sample of ~50 stars observed with sufficient duration and quality to detect a giant planet at 5 AU, implying that such planets are not rare. The properties of this jupiter analog may be compared directly to those of the Jovian planets in our Solar System. Its eccentricity is modest, e=0.16, compared with e=0.05 for both Jupiter and Saturn. Its mass is at least 4.0 jupiter masses (M sin i). The two planets do not perturb each other significantly. Moreover, a third planet of sub-Jupiter mass could easily survive in between these two known planets. Indeed a third periodicity remains in the velocity measurements with P = 44.3 d and a semi-amplitude of 13 m/s. This periodicity is caused either by a third planet at a=0.24 AU or by inhomogeneities on the stellar surface that rotates with period 42 d. The planet interpretation is more likely, as the stellar surface is quiet, exhibiting log(R'_{HK}) = -5.0 and brightness variations less than 1 millimag, and any hypothetical surface inhomogeneity would have to persist in longitude for 14 yr. Even with all three planets, an additional planet of terrestrial--mass could orbit stably at ~1 AU. The star 55 Cancri is apparently a normal, middle-aged main sequence star with a mass of 0.95 solar masses, rich in heavy elements ([Fe/H] = +0.27). This high metallicity raises the issue of the relationship between its age, rotation, and chromosphere.Comment: 47 pages, 4 tables, 12 figures, uses AASTE

Galactic Evolution of Nitrogen

We present detailed spectroscopic analysis of nitrogen abundances in 31 unevolved metal-poor stars analysed by spectral synthesis of the near-UV NH band at 3360 A observed at high resolution with various telescopes. We found that [N/Fe] scales with that of iron in the metallicity range -3.1 < [Fe/H] <0 with the slope 0.01+-0.02. Furthermore, we derive uniform and accurate (N/O) ratios using oxygen abundances from near-UV OH lines obtained in our previous studies. We find that a primary component of nitrogen is required to explain the observations. The NH lines are discovered in the VLT/UVES spectra of the very metal-poor subdwarfs G64-12 and LP815-43 indicating that these stars are N rich. The results are compared with theoretical models and observations of extragalactic HII regions and Damped Ly$\alpha$ systems. This is the first direct comparison of the (N/O) ratios in these objects with those in Galactic stars.Comment: 10 pages, 6 figures, to appear in Astronomy and Astrophysic