7,445 research outputs found

    Lesiones de la articulación tarso-metatarsiana

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    Se presentan 16 casos de fractura-luxación tarso-metatarsiana. El objetivo de este trabajo ha sido la valoración de los resultados finales en este tipo de patología. La etiología del accidente ha sido en 6 ocasiones casual o deportiva, en 5 laboral, en 4 accidente de tráfico y 1 caída de un caballo. Las fractura-luxaciones han sido clasificadas según los criterios de Hardcastle, resultando 3 casos tipo A externo, 6 B externo, 6 B interno y 1 C total. El tratamiento realizado fue mayoritariamente reducción y osteosíntesis con agujas de Kirschner, predominando la reducción abierta. Se ha considerado parámetros radiográficos y clínicos, siguiendo los criterios del Baltimore Painful Foot Store para la valoración de resultados finales, obteniéndose 9 casos excelentes, 4 buenos, 2 reguladores y 1 malo. Se concluye que es fundamental el diagnóstico y tratamiento precoz, considerando básica la reducción anatómica estabilizada con agujas de Kirschner.We report 16 cases of tarsometatarsal fracture-dislocation. The purpose of this work was the assessment of the final outcome of these cases. The etiology was casual or sport injuries in 6 cases, industrial accidents in 5, traffic accidents in 4 and fall off a horse in 1 case. The injuries have been classified according to the Hasrdcastle modified classification, being 3 cases type A external, 6 B internqal and 1 C total. In most cases the treatment was open reduction and internal fixation with Kirschner wires. According to the guidelines of the Balitmore Painful Score for the evaluation of final outcome, there were 9 excellent results, 4 good, 2 fair and 1 poor. We conclude that the best results were obtained in those cases with early diagnose and treatment, looking for an anatomical reduction and fixation with Kirschner wires

    Efeitos de ethephon e uréia na maturação de frutos e abscisão foliar do cafeeiro (Coffea arábica L.)

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    A field experiment was carried out to investigate the effects of ethephon and urea on ripening of fruits and leaf abscission of coffee plant. Ethephon (2-chloroethane phosphonic acid) sprays were applied to green Coffea arábica berries 26 days before counting date in concentrations of 0.5 and 0.25 ml/1 from Ethrel (240 a.i./l). The chemical accelerated the onset of fruit ripening at both concentrations. The efficacy of ethephon was increased adding urea. Ethephon 0.5 ml/1 promoted abscission of leaves and low concentration reduced shedding of leaves. The treatments did not affect the growth and production on the next harvest.Como o ethephon pode melhorar a uniformidade na maturação dos frutos e uréia pode aumentar a eficácia do regulador vegetal, estes compostos foram utilizados no estudo da maturação e abscisão foliar em cafeeiro. E-thephon (ácido 2-cloroetilfosfônico) foi pulverizado em Coffea arábica cv. CatuaT Vermelho com frutos verdes, nas dosagens de 0,5 e 0,25 ml/l de Ethrel (240g i.a./l). 0 regulador vegetal acelerou a maturação dos frutos em ambas dosagens e adicionando-se uréia 2%, conforme determinações realizadas 26 dias após os tratamentos. A eficiência do ethephon foi incrementada com adição de uréia. Ethephon 0,5 ml/l provocou absci são foi iar, sendo que a dosagem de 0,25 ml/1 reduziu a queda das folhas do cafeeiro. Os tratamentos não afetaram o desenvolvimento dos ramos e a frutificação na safra seguinte

    Voltage-driven quantum oscillations in graphene

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    We predict unusual (for non-relativistic quantum mechanics) electron states in graphene, which are localized within a finite-width potential barrier. The density of localized states in the sufficiently high and/or wide graphene barrier exhibits a number of singularities at certain values of the energy. Such singularities provide quantum oscillations of both the transport (e.g., conductivity) and thermodynamic properties of graphene - when increasing the barrier height and/or width, similarly to the well-known Shubnikov-de-Haas (SdH) oscillations of conductivity in pure metals. However, here the SdH-like oscillations are driven by an electric field instead of the usual magnetically-driven SdH-oscillations.Comment: 4 pages, 4 figure

    Detección de células secretoras de anticuerpos totales y específicas de rotavirus en adultos sanos

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    Antibodies (Ab) play a critical role in the immune response against rotavirus (RV). Protector Ab, are produced by antibody secreting cells (ASC). The capacity to detect ASC becomes fundamental in process like antiviral response analysis and vaccination testing. Here, we analyzed the frequency and isotype of total and RV-specific ASC by ELISPOT (functional assay) and flow cytometry (FC) in healthy adults using CD38and CD27 like ASC markers. In each million of peripherals blood mononuclear cells (PBMC), approximately 2,550 totals ASC were detected. IgA was the isotype preferentially expressed for circulating ASC followed by IgG and IgM with 63%, 29.4% and 7.6% of total ASC respectively. Paired analysis of immunomagnetic sorting, ELISPOT and FC shown that 85% and 90% of total ASC expressed CD38 and CD27 respectively. CD38 and CD27 ASC enrichment population were used to detect RV-specific ASC. None to 40 ASC per million of PBMC were detected by ELISPOT and FC and more interesting yet, a high correlation were found in the frequency of RV-specific ASC detected by both methods. This mixture assay can be used in the evaluation of new RV vaccines.Ya que los anticuerpos (Ac) son uno de los principales mecanismos de defensa contra la infección por rotavirus (RV), la capacidad de identificar a las células que secretan anticuerpos (CSA) totales y RV específicos es fundamental para procesos como el análisis de la respuesta inmune antiviral y la evaluación de nuevas vacunas. Aquí, se analiza por ELISPOT (ensayo funcional) y citometría de flujo (CF ensayo fenotípico) la frecuencia e isotipo de CSA totales y RV específicas en adultos sanos, usando células mononucleares de sangre periférica totales (CMSP) y a las moléculas CD38 y CD27 como marcadores para enriquecer en CSA. Por cada millón de CMSP, aproximadamente 2,550 células producían Ac totales. La IgA fue el isotipo más frecuente, seguido de la IgG e IgM, con el 63%, 29.4% y 7.6% respectivamente. El análisis combinado del ELISPOT y la CF mostró que el 85% de las CSA expresaron CD38 y el 90% de ellas expresaron CD27. Una alta y significativa correlación entre las CSA detectadas por el ensayo funcional y el fenotípico fue encontrada cuando estos ensayos se realizaron en las poblaciones purificadas con CD38 y CD27. Con el enriquecimiento de CSA usando al CD38 y CD27, se logró además detectar CSA RV específicas que se encuentran en circulación en tan baja frecuencia como 0 a 40 CSA-RV por millón de CMSP. Para las células RV específicas, también una buena correlación fue encontrada entre el ELISPOT y la CF. A pesar de su muy baja frecuencia, CSA antígeno específicas pueden ser detectadas en circulación de voluntarios sanos. Este acercamiento puede ser usado en la evaluación de vacunas, que para el caso particular del RV son necesarias mejorar

    Simple models of the chemical field around swimming plankton

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    Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection. HLA ligands are recognized by killer immunoglobulin-like receptors (KIRs) expressed on a range of immune cell subsets, governing their proinflammatory activity. We hypothesized that the inheritance of particular HLA-KIR combinations would increase cervical neoplasia risk. Methods. Here, we used HLA and KIR dosages imputed from single-nucleotide polymorphism genotype data from 2143 cervical neoplasia cases and 13 858 healthy controls of European decent. Results. The following 4 novel HLA alleles were identified in association with cervical neoplasia, owing to their linkage disequilibrium with known cervical neoplasia-associated HLA-DRB1 alleles: HLA-DRB3*9901 (odds ratio [OR], 1.24; P = 2.49 × 10−9), HLA-DRB5*0101 (OR, 1.29; P = 2.26 × 10−8), HLA-DRB5*9901 (OR, 0.77; P = 1.90 × 10−9), and HLA-DRB3*0301 (OR, 0.63; P = 4.06 × 10−5). We also found that homozygosity of HLA-C1 group alleles is a protective factor for human papillomavirus type 16 (HPV16)-related cervical neoplasia (C1/C1; OR, 0.79; P = .005). This protective association was restricted to carriers of either KIR2DL2 (OR, 0.67; P = .00045) or KIR2DS2 (OR, 0.69; P = .0006). Conclusions. Our findings suggest that HLA-C1 group alleles play a role in protecting against HPV16-related cervical neoplasia, mainly through a KIR-mediated mechanism

    Non-adiabatic and time-resolved photoelectron spectroscopy for molecular systems

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    We quantify the non-adiabatic contributions to the vibronic sidebands of equilibrium and explicitly time-resolved non-equilibrium photoelectron spectra for a vibronic model system of Trans-Polyacetylene. Using exact diagonalization, we directly evaluate the sum-over-states expressions for the linear-response photocurrent. We show that spurious peaks appear in the Born-Oppenheimer approximation for the vibronic spectral function, which are not present in the exact spectral function of the system. The effect can be traced back to the factorized nature of the Born-Oppenheimer initial and final photoemission states and also persists when either only initial, or final states are replaced by correlated vibronic states. Only when correlated initial and final vibronic states are taken into account, the spurious spectral weights of the Born-Oppenheimer approximation are suppressed. In the non-equilibrium case, we illustrate for an initial Franck-Condon excitation and an explicit pump-pulse excitation how the vibronic wavepacket motion of the system can be traced in the time-resolved photoelectron spectra as function of the pump-probe delay

    The challenge of preparing teams for the European robotics league: Emergency

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    © 2017, Society for Imaging Science and Technology. ERL Emergency is an outdoor multi-domain robotic competition inspired by the 2011 Fukushima accident. The ERL Emergency Challenge requires teams of land, underwater and flying robots to work together to survey the scene, collect environmental data, and identify critical hazards. To prepare teams for this multidisciplinary task a series of summer schools and workshops have been arranged. In this paper the challenges and hands-on results of bringing students and researchers collaborating successfully in unknown environments and in new research areas are explained. As a case study results from the euRathlon/SHERPA workshop 2015 in Oulu are given
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