7 research outputs found
Umsetzungsprobleme der Impressumspflicht bei Webangeboten
Der Beitrag behandelt die Anforderungen von TDG und MDStV an die Anbieterkennzeichnung für Inhalte im World Wide Web (WWW). Der Autor untersucht dabei insbesondere die Probleme, die im Rahmen der praktischen Umsetzung der Vorschriften auftreten können
Current Issues in IT Security
The conference "Current Issues in IT Security" brought researchers and practitioners from various disciplines together at the Max Planck Institute for Foreign and International Criminal Law in Freiburg, Germany. IT professionals, lawyers, law enforcement and intelligence officers, judges, prosecutors, forensic specialists, and psychologists all contributed their special expertise to the discussion on contemporary security issues.
This volume of conference proceedings provides an insight into twelve of the topics that were discussed during the three-day conference. It highlights the importance of an interdisciplinary approach to security-related issues, especially in the field of IT security
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA sequence, but can influence its function. Currently, DNA methylation is the most studied epigenetic phenomenon in large populations. It entails the binding of a methyl group, mainly to positions in genomic DNA where a cytosine is located next to a guanine, a cytosine-phosphate-guanine (CpG) site (Figure 1). DNA methylation at CpG sites can influence gene expression by altering the DNA’s three-dimensional structure and interacting with methyl-binding proteins, consequently affecting the binding of the gene transcription and chromatin-modifying machinery. There are approximately 28 million CpG sites in the human genome. DNA methylation is a dynamic process that can be influenced by genetic factors, as well as by environmental factors such as diet, air pollution, toxicants or smoking.1–4 Hence, DNA methylation may be seen as linking the genome to the environment with respect to health and disease. Early development is a period of profound changes in DNA methylation and may, as such, be a critical period for environmentally-induced DNA methylation changes.4 Hence, this period is of specific interest for DNA methylation studies in relation to specific exposures and long-term health outcome