A survey on the public perception of CCS in France

An awareness and opinion survey on Carbon Capture and Storage was conducted on a representative sample of French aged 15 years and above. About 6\% of respondents were able to provide a satisfying definition of the technology. The key question about `approval of or opposition to' the use of CCS in France was asked twice, first after presenting the technology, then after exposing the potential adverse consequences. Approval rates, 59\% and 38\%, show that there is no a priori rejection of the technology. The sample was split in two to test for a semantic effect: questioning one half about `Stockage' (English: storage), the other about `Sequestration'. Manipulating the vocabulary had no statistically significant effect on approval rates. Stockage is more meaningful, but does not convey the idea of permanent monitoring.Carbon capture and storage; public opinion

Molecular recognition of tumor-associated antigens by lectins and antibodies

Every living cell on Earth is covered by glycans. They are inserted in proteins and lipids by a posttranslational modification called glycosylation. Their recognition by specific receptors is translated into distinct biological signals. In cancer cells, a misregulation in expression and/or activity of glycosyltransferases, alters the mechanism of glycosylation, creating new glycan epitopes dubbed tumor-associated carbohydrate antigens (TACAs). These are recognized by various receptors, playing a major role in tumor immune responses and metastasis. To target cancer-associated glycan phenotype is crucial to disentangle the molecular recognition process that involves TACAs recognition and biosynthesis. Therefore, NMR techniques were employed to investigate distinct glycan-protein systems: i) the molecular interactions between a mucin-1 (MUC1) related Tn-glycopeptide mimetic containing a non-natural amino acid and distinct antibodies by saturation transfer-difference (STD-NMR); ii) the molecular interactions between galectin-3 (Gal-3) and TF-antigen (TF-Thr and TF-peptide), by heteronuclear single quantum coherence 1H,15N-HSQC titrations, STD-NMR and line broadening analysis and iii) the glycosylation of MUC1 tandem repeated protein (G1VT3S4APDT8RPAPGS14T15APPAH20)4 by GalNAc-T3 using 1H,15N-HSQC and STD-NMR. In i), the STD-NMR binding experiments show that all antibodies under study recognize the Tn-glycopeptide mimetic and point out structural differences that explain antibodies’ binding preferences. In ii), the 1H,15N-HSQC titrations experiments indicate that Gal-3 binds both TF-derivatives. The dissociation constant KD estimated for both through chemical shift analysis also shows the same range of affinity (275 μM and 413 μM for TF-antigen and TF-peptide, respectively). STD-NMR results demonstrate that the protons from galactose in the TF-moiety govern the recognition process of Gal-3. In iii), the 1H,15N-HSQC experiments of MUC1 in presence of GalNAc-T3 show that the enzyme has preference to glycosylate first the Thr at –GVTS-, followed by the residue Thr at –GSTA-. STD-NMR confirms the cooperative mechanism between the lectin and catalytic domain of GalNAc-T3

Prediction of bacterial meningitis based on cerebrospinal fluid pleocytosis in children

AbstractChildren with cerebrospinal fluid pleocytosis are frequently treated with parenteral antibiotics, but only a few have bacterial meningitis. Although some clinical prediction rules, such as bacterial meningitis score, are of well-known value, the cerebrospinal fluid white blood cells count can be the initial available information. Our aim was to establish a cutoff point of cerebrospinal fluid white blood cell count that could distinguish bacterial from viral and aseptic meningitis. A retrospective study of children aged 29 days to 17 years who were admitted between January 1st and December 31th, 2009, with cerebrospinal fluid pleocytosis (white blood cell≥7μL−1) was conducted. The cases of traumatic lumbar puncture and of antibiotic treatment before lumbar puncture were excluded. There were 295 patients with cerebrospinal fluid pleocytosis, 60.3% females, medium age 5.0±4.3 years distributed as: 12.2% 1–3 months; 10.5% 3–12 months; 29.8% 12 months to 5 years; 47.5% >5 years. Thirty one children (10.5%) were diagnosed with bacterial meningitis, 156 (52.9%) viral meningitis and 108 (36.6%) aseptic meningitis. Bacterial meningitis was caused by Neisseria meningitidis (48.4%), Streptococcus pneumoniae (32.3%), other Streptococcus species (9.7%), and other agents (9.7%). cerebrospinal fluid white blood cell count was significantly higher in patients with bacterial meningitis (mean, 4839cells/μL) compared to patients with aseptic meningitis (mean, 159cells/μL, p<0.001), with those with aseptic meningitis (mean, 577cells/μL, p<0.001) and with all non-bacterial meningitis cases together (p<0.001). A cutoff value of 321white blood cell/μL showed the best combination of sensitivity (80.6%) and specificity (81.4%) for the diagnosis of bacterial meningitis (area under receiver operating characteristic curve 0.837). Therefore, the value of cerebrospinal fluid white blood cell count was found to be a useful and rapid diagnostic test to distinguish between bacterial and nonbacterial meningitis in children

Perturbações do sono em adultos idosos hospitalizados

Resumo Contexto: O sono é um bem precioso e indispensável a um bom equilíbrio. O processo de envelhecimento ocasiona perturbações que se refletem tanto na quantidade como na qualidade do sono, sendo estas alterações agravadas em situações de hospitalização. Objetivos: Avaliar perturbações do sono dos utentes adultos/idosos internados e analisar relação com variáveis sociodemográficas, clínicas e fadiga crónica. Metodologia: Trata-se de um estudo transversal, descritivo e correlacional, do tipo quantitativo. Para o efeito foi aplicado um formulário a 60 utentes, internados, que incluía variáveis sociodemográficas, uma Escala de Fadiga Crónica e o Índice de Qualidade do Sono de Pittsburg (IQSP). Resultados: A amostra é maioritariamente constituída por utentes do sexo masculino, casados, com 75 anos e analfabetos. Realizam programa de reabilitação diariamente entre 16 a 30 minutos e apenas algumas vezes se sentem aptos para o concretizar. A maioria (55,00%) sente-se mais ativo no período da tarde, dorme em media 6,8 horas, acorda muitas vezes e mais cedo do que o pretendido. A fadiga crónica está presente na grande maioria dos inquiridos, sentindo estes que precisam de dormir mais do que normalmente dormem. Conclusões: A maioria dos participantes (96,70%) apresenta perturbações de sono no internamento, sendo estas mais graves nos utentes com índices mais elevados de fadiga crónica, com mais idade, nas mulheres e nos viúvos. Palavras-chave: Perturbações do sono, utentes, idosos, hospitalização.Abstract Background: Sleep is precious and indispensable to a good balance. The aging process causes disturbances which reflect both the quantity and quality of sleep, being that these changes are aggravated in hospital situations. Objectives: To evaluate sleep disorders of adults / hospitalized elderly patients and analyze the relationship with sociodemographic variables, clinical and chronic fatigue. Methodology: This is a cross-sectional, descriptive and correlational study, of the quantitative type. For this purpose, a questionnaire was applied to 60 users, hospitalized, that included sociodemographic variables, a Chronic Fatigue Scale and the Sleep Quality Index of Pittsburgh (PSQI). Results: The sample is mostly made up of male users, married, 75 years old and illiterate. They have performed their rehabilitation program daily between 16-30 minutes and only a few times do they feel ready to finish. The majority (55.00%) feel more active at afternoon, they sleep on average 6.8 hours, wake up often and sooner than intended. Chronic fatigue is present in the vast majority of respondents, with these feeling that they need to sleep more than what they normally sleep. Conclusions: The majority of participants (96.70%) present sleep disorders during hospitalization, with this being associated to users with higher rates of chronic fatigue, of an older age, women and widows.info:eu-repo/semantics/publishedVersio

A survey on the public perception of CCS in France

International audienceAn awareness and opinion survey on Carbon Capture and Storage was conducted on a representative sample of French aged 15 years and above. About 6\% of respondents were able to provide a satisfying definition of the technology. The key question about 'approval of or opposition to' the use of CCS in France was asked twice, first after presenting the technology, then after exposing the potential adverse consequences. Approval rates, 59\% and 38\%, show that there is no a priori rejection of the technology. The sample was split in two to test for a semantic effect: questioning one half about 'Stockage' (English: storage), the other about 'Sequestration'. Manipulating the vocabulary had no statistically significant effect on approval rates. Stockage is more meaningful, but does not convey the idea of permanent monitoring

The psychologic intervention with young people: educational perspective

The present article intends to realize the design, educational/pedagogical, focusing on the need to equate its foundations or ideologies, its purposes and its objectives, as well as all other instrumental components. Roughly, it attempts to operationalize and exemplify its great questions: what, why, for what and how. And while an example is proposed as a kindergarten, the suggested architecture is amenable to extension to others, or to all, contexts and educational situations.info:eu-repo/semantics/publishedVersio

Synthèse de littérature sur l'acceptabilité sociale du captage et du stockage du CO2

L'analyse d'une vingtaine de publications scientifiques, publiée entre 2001 et 2006, portant sur l'acceptabilité sociale et la perception du captage et stockage du CO2 (CCS) a été réalisée. Cette analyse vise à rendre compte des différents aspects considérés et des méthodes utilisées pour estimer l'acceptabilité. Les références consultées convergent vers le constat d'une méconnaissance actuelle de la technologie du CCS par le public et incitent à la prudence avant de conclure à l'adhésion ou au rejet inconditionnel par le public

o contributo do enfermeiro especialista de reabilitação

Mestrado, Enfermagem de Reabilitação, 2014, Escola Superior de Enfermagem de LisboaA DPOC é uma doença crónica constituindo uma das principais causas de morbilidade e mortalidade em todo o mundo. É caracterizada por uma limitação do débito aéreo, devido a uma resposta anómala a nível pulmonar à inalação de partículas ou gases. A evolução da doença e a manifestação de sintomas despoleta défice de autocuidado. Deste modo, o EEER no âmbito das suas competências desenvolve intervenções que visam o readquirir do autocuidado e autonomia da pessoa com DPOC. No âmbito do mestrado na área de especialização em Enfermagem de Reabilitação, foi concebido um projeto de estágio operacionalizado ao longo dos estágios realizados. A temática do projeto é referente à promoção do autocuidado da pessoa com DPOC e compreensão do contributo do EEER. Este percurso culminou com a elaboração deste relatório, onde para além de dar resposta à temática do projeto, é realizada uma descrição, análise e reflexão dos objetivos e atividades desenvolvidas que permitiram o desenvolvimento de competências como futura EEER. Durante o estágio desenvolvido no serviço de Pneumologia, constatei que na pessoa com DPOC, a reabilitação respiratória, nomeadamente a RFR e treino de exercício, melhoram a gestão da doença, reduzindo a dispneia, promovendo a readaptação ao esforço, a autonomia e autocuidado. É fundamental envolver a família no processo de reabilitação, pois esta assume um papel primordial no que diz respeito à preparação para o regresso a casa destes doentes. No estágio desenvolvido no serviço de Neurologia, foi possível desenvolver competências sobretudo no âmbito da reabilitação motora da pessoa com patologia do foro sensório-motor. Neste percurso, foram mobilizados conhecimentos teóricos com a prática clinica, à luz da teoria de enfermagem de Dorothea Orem, de modo a num processo dinâmico de aprendizagem e construção de saberes, traçar uma identidade profissional como futura EEER

Representações sobre indisciplina em adolescentes

Dissertação de mestrado apresentada ao ISPA - Instituto UniversitárioO presente estudo teve objetivo analisar as representações que os alunos do 7º, 8º e 9º ano de escolaridade do Ensino Regular e 8º e 9º ano de escolaridade do Curso de Educação e Formação (CEF) têm acerca da indisciplina. Assim, e como forma de efetuar esta análise, foi realizado um estudo quantitativo de caráter comparativo e correlacional. No presente estudo participaram 200 alunos, do 3º Ciclo do Ensino Básico de duas escolas públicas do Concelho de Almeirim, sendo utilizado como instrumento, um questionário. Os dados evidenciaram que, de uma forma global, as representações sobre a indisciplina diferem em parte em função do género, da faixa etária e do tipo de ensino. Por outro lado, não se verificou qualquer relação significativa entre a variável “habilitações literárias dos pais” e a representação dos participantes sobre indisciplina.ABSTRACT------The goal of this study is to assess the notions that middle school students from both regular school and special education have of the concept of indiscipline. With this in mind, a quantitative study of comparative data and correlation was made: 200 hundred middle school students that attend one of these programs were chosen from two schools in the Almeirim county and submitted to an inquiry. The data provided by the inquiry’s answers suggests that the notions the students have of indiscipline change with gender, age range and type of school. On the other hand, it does not establish a connection between their definition of indiscipline and the qualifications of the average citizen