Theoretical insight into the antioxidant, electronic and anticancer behaviour of simmondsin

Simmondsin is a type of flavonoid it belongs to the group of flavan-3-ols (or simply flavanols (phenols). Phenolic compounds are known as antioxidants. In this study, we explain simmondsin’s antioxidant mechanism and investigate it to determine if it can be used as an anticancer therapeutic agent or not. Our results show that simmondsin is a very strong antioxidant that prefers hydrogen atom transfer (HAT) mechanism and can be benefited as an anticancer therapeutic agent. Hence, it can be used in cancer drugs to decrease the harmful effects of cancer cure

Evaluation of Sleep and Television Viewing Habits of Primary School Students

Objective: Sleep is crucial for healthy growth and development of children. Unsuitable television viewing habits are one of the important factors that disturb sleep patterns. This study was conducted to evaluate the sleep and television viewing habits of primary school students. Materials and Methods: The study was conducted as a descriptive study. The data were collected from parents of students aged 6-11 years, who were studying at a primary school between December 2016 and February 2017. The study sample consisted of 299 parents. In order to collect data, a personal information form, an information form to determine television viewing habits and the Children’s Sleeping Habits Questionnaire were administered to the study subjects. Percentages, means, standard deviations, frequencies, and analysis of variance were used to evaluate the data. Ethical permission and consent from the parents were taken for conducting the study. Results: The mean age of the children was 8.64±1.16, and the parents’ mean age was 35.55±6.23. The mean number of hours spent viewing television was 5.62 hours per day. The mean sleep time of the children was 9.37 hours. The mean total score obtained from Children’s Sleeping Habits Questionnaire was determined to be 47.92±8.18. Conclusion: It was found that the child’s success at school, the television viewing time during the weekday, the child’s preference for viewing time, the response to being asked to turn the television off, and the parents’ viewing time significantly affected the total Children’s Sleeping Habits Questionnaire score. A significant difference was found between parental income status, educational status, school success, bedtime resistance, and sleep duration. Also, a significant difference was found between television viewing habits and at least one sleep problem, except night wakes

Quality changes of sucuks produced with turkey meat and olive oil during fermentation and ripening

[EN] In this study, it was aimed to determine the effects of partial replacement of beef fat with olive oil on quality changes of fermented turkey sausages (sucuk) during processing. Three formulations were prepared by using the lipid phase as 100% beef fat (control), 85% beef fat+15% olive oil and 70% beef fat+30% olive oil. Total moisture, pH, acidity, water activity (aw) and peroxide values were analyzed in sausage dough, at the end of the fermentation and at the end of ripening. The production steps significantly affected moisture decrease in samples, pH and aw values were decreased and acidity was increased in all samples during production. Peroxide value of the samples increased during processing steps and the samples with olive oil had higher peroxide values compared to control. The results showed that during processing steps of fermented turkey sausages, considerable changes could occur depending on lipid type.The authors gratefully acknowledge the financial support from the Scientific and Technological Research Council of Turkey (TUBITAK) under the project number: 214-O181.Zungur-Bastıoğlu, A.; Serdaroğlu, M.; Öztürk, B.; Nacak, B. (2018). Quality changes of sucuks produced with turkey meat and olive oil during fermentation and ripening. En IDS 2018. 21st International Drying Symposium Proceedings. Editorial Universitat Politècnica de València. 1179-7. https://doi.org/10.4995/IDS2018.2018.7966OCS1179

(E,E)-1-(2-Hydroxy­imino-1-phenyl­ethyl­idene)semicarbazide monohydrate

In the title compound, C9H10N4O2·H2O, the oxime unit has an E configuration, and an intra­molecular N—H⋯N hydrogen bond results in the formation of a planar five-membered ring, which is oriented with respect to the aromatic ring at a dihedral angle of 74.82 (17)°. In the crystal structure, inter­molecular O—H⋯O and N—H⋯O hydrogen bonds link the mol­ecules and R 2 2(8) ring motifs are apparent

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Flourier grid hamiltonyen metodu ile bağlı durum özdeğerlerinin ve özfonksiyonlarının hesaplanması

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.In this work, bound state energy eigenvalues and eigenfunctions of the OH, HC1, LİF and CO molecules were calculated by using Fourier Grid Hamiltonian Method. The interactions between molecular atoms were represented by Morse Potential. The number of the bound state energy eigenvalues of the OH, HC1, LiF and CO molecules were calculated 22, 23, 55, 66 respectively. The energy eigenvalues of each molecule were plotted on the potantial curve The eigenfunctions corresponding to some eigenvalues were plotted with respect to interatomic distance. The eigenfunctions for OH molecule in its v=0 and v=6 vibrational quantum states and those of LiF moleculein its v=4 and v=l 1 vibrational states are given by tables. Keywords: Eigenvalues, eigenfunctions, FGH, fourier transform method.Bu çalışmada; OH, HC1, LİF ve CO moleküllerinin bağlı durum enerji özdeğerleri ve özfonksiyonlan Fourier Grid Hamiltonyen Metodu kuUanılarak hesaplandı. Molekül atomları arasındaki etkileşmeler Morse Potansiyeli ile temsil edildi. OH, HC1, LİF ve CO moleküllerinin bağlı durum enerji özdeğerleri sayısı sırasıyla; 22, 23, 55 ve 66 olarak hesaplandı. Her molekülün enerji özdeğerleri, potansiyel eğrisi içerisinde çizildi. Bazı enerji özdeğerlerine karşı gelen özfonksiyonlann konum koordinatına bağlı değişim grafikleri çizildi. OH molekülünün v= 0, 6 kuantum durumuna karşı gelen enerji özdeğerine ait özfonksiyonlann ve LİF molekülünün v= 4, 11 kuantum durumuna karşı gelen enerji özdeğerlerine ait özfonksiyonlann her grid noktasında aldığı değerler çizelgeler halinde verildi. Anahtar Kelimeler: Özdeğer, özfonksiyon, FGH, fourier dönüşüm metodu

The Role Of Global Brands In Replacement Of The Citizenship Identity With The Changing Consumer Identıty: Study On University Students

Günümüzde tüketim kavramı yaşanılan sosyal ve teknolojik gelişmeler sonucunda farklılaşmış durumdadır. Bu süreç içinde giderek öne çıkan tüketim olgusu ile hayat bir tüketim deneyimi olarak sunulmaktadır. Tüketim, üretim kavramından sıyrılıp tüketim kültürüne, küresel markaların tüm dünyaya yayılması ile marka ve imaj kültürüne dönüşmektedir. Statü ya da sosyal sınıf belirtmek, kendini tanımlayıp bir role bürünmek, sosyal varlığını oluşturmak ve koruyabilmek, kendini başkalarına ifade edebilmek, sosyalleşmek, kimliğini yansıtmak gibi sebeplerle günümüzde insanlar tüketime yönelmektedirler. Üretim ikinci plana atılmakta, ürünleri markalamak ve marka imajı oluşturmak, ürünler hakkında farkındalık yaratmak amacıyla çalışmalar yapılmaktadır. Bu noktada küresel şirketlerin yarattığı marka kimlikleri ve tüketim alanlarının değişimi ile sunulan imajlar çerçevesinde bireylerin yaşam tarzları ve kim olduklarını yansıtma araçları olan kimlikleri inşa edilmektedir. Bunlara bağlı olarak, günümüz tüketim dünyasında algılama ve pazarlama uygulamaları kapsamında küresel markaların tüketicilere özgü bir vatandaşlık, aidiyet kimliği yaratarak bireylerin satın alma davranışlarını etkilemeleri, değişen tüketici kimliği bağlamında değerlendirilmiştir.Nowadays, the notion of consumption has already been differentiated as a result of social and technological developments which are met. Within this period, with the consumption fact that is graduallz becoming prominent, life is offered as a consumption experiment. Eluded from the notion of production, the consumption turns out brand and image culture with the expand of global brands around the world. Nowadays people tend towards the consumption with the reasons such as remarking status and social class, playing a role by defining itself, creating and protecting its social being, signifying itself to others, socializing, reflecting its identity. Consumption is pushed into the background, studies are held on the purpose of branding the products and creating brand image, creating awareness about the products. At this point, people's identities which are the means of reflecting their lifestyles and who they are as part of brand identities created by global companies and the images offered with the alteration of consuption areas. Therefore, in our today's consumtion world, within the perception and marketing practices, by creating a citizenship, ownership identity peculiar to the consumers, global brands affects on buying behaviour was evaluated within changing consumer identity