Santiago Vidaurri. La formación de un liderazgo regional desde Monterrey, 1809-1867

Conjunto de ensayos sobre la trayectoria política y militar de Santiago Vidaurri que fue gobernador de Coahuila y Nuevo León entre 1856-1864. Producto de una revisión intensiva de los archivos privados sobre el personaje y de los localizados también en el extranjero. Incluye una cronología, bibliografía sobre el personaje y un indice onomástico

A Trypanosoma cruzi monoclonal antibody that recognizes a superficial tubulin-like antigen

A monoclonal antibody (MAB 10), obtained from mice infected with Trypanosoma cruzi, was found to recognize a superficial antigen in living or fixed parasites. It reacted more strongly with T. cruzi than with related parasites such as T. brucei and Leishmania. In immunoblots it recognized a single trypanosoma polypeptide and also brain tubulin, both of which had the same electrophoretic mobility. Further analysis suggested that the α-tubulin subunit contained the epitope recognized by MAB 10. These results suggest that a surface tubulin-like protein is present in T. cruzi.Peer Reviewe

Sistema móvil de información basado en una red de sensores inalámbricos aplicado a la movilidad urbana

La movilidad en las ciudades se ve comprometida por un tráfico cada vez más elevado y unas infraestructuras que no pueden ampliarse. Por tanto, la mejora de la movilidad y su sostenibilidad deben venir de la mano de una mejor gestión de los recursos, con la incorporación de estrategias de control del tráfico que se adapten en cada momento a sus condiciones. El principal obstáculo está en la obtención de esa información. Una posibilidad son las redes de sensores inalámbricos, que pueden aportar información sobre las condiciones en una zona de interés, con vistas a una planificación más eficiente y al despliegue de algoritmos de control más elaborados.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Agencia de Obra Pública de la Junta de Andalucía (proyecto GI3000/IDIZ, con apoyo financiaero de los fondos FEDER

Integration of a Canine Agent in a Wireless Sensor Network for Information Gathering in Search and Rescue Missions

Search and rescue operations in the context of emergency response to human or natural disasters have the major goal of finding potential victims in the shortest possible time. Multi-agent teams, which can include specialized human respondents, robots and canine units, complement the strengths and weaknesses of each agent, like all-terrain mobility or capability to locate human beings. However, efficient coordination of heterogeneous agents requires specific means to locate the agents, and to provide them with the information they require to complete their mission. The major contribution of this work is an application of Wireless Sensor Networks (WSN) to gather information from a multi-agent team and to make it available to the rest of the agents while keeping coverage. In particular, a canine agent has been equipped with a mobile node installed on a harness, providing information about the dog’s location as well as gas levels. The configuration of the mobile node allows for flexible arrangement of the system, being able to integrate static as well as mobile nodes. The gathered information is available at an external database, so that the rest of the agents and the control center can use it in real time. The proposed scheme has been tested in realistic scenarios during search and rescue exercises

Muscle damage, physiological changes and energy balance in ultra-endurance mountain event athletes

The biological response to ultra-endurance mountain race events is not yet well understood. The aim of this study was to determine the biochemical and physiological changes after performing an ultra-endurance mountain race in runners. We recruited 11 amateur runners (age: 29.7 ± 10.2 years; height: 179.7 ± 5.4 cm; body mass: 76.7 ± 10.3 kg). Muscle damage, lactate concentration, energy balance, rating of perceived exertion (RPE), heart rate (HR), heart rate variability (HRV), body composition changes, and jump performance were analyzed before, during (only lactate, HR, and HRV), and after the race. Athletes completed 54 km in 6 h, 44 min (±28 min). After the race, myoglobin and creatine kinase concentration increased from 14.9 ± 5.2 to 1419.9 ± 1292.1 μg/L and from 820.0 ± 2087.3 to 2421.1 ± 2336.2 UI/L, respectively (p < 0.01). In addition, lactate dehydrogenase and troponin I significantly increased after the race (p < 0.01). Leukocyte and platelet count increased by 180.6% ± 68.9% and 23.7% ± 11.2%, respectively (p < 0.001). Moreover, after the competition, athletes presented a 3704 kcal negative energy balance; a significant increase in RPE values; a decrease in countermovement and squat jump height; and a decrease in body mass and lower limb girths. During the event, lactate concentration did not change and subjects presented a mean HR of 158.8 ± 17.7 beats/min, a significant decrement in vagal modulation, and a significant increase in sympathetic modulation. Despite the relative “low” intensity achieved, ultra-endurance mountain race is a stressful stimulus that produces a high level of muscle damage in the athletes. These findings may help coaches to design specific training programs that may improve nutritional intake strategies and prevent muscle damage.Actividad Física y Deport

Differential profile of protein expression on human keratocytes treated with autologous serum and plasma rich in growth factors (PRGF)

Purpose The main objective of this study is to compare the protein expression of human keratocytes treated with Plasma rich in growth factors (PRGF) or autologous serum (AS) and previously induced to myofibroblast by TGF-beta 1 treatment. Methods Blood from healthy donor was collected and processed to obtain AS and PRGF eye drops. Blood derivates were aliquoted and stored at-80 degrees C until use. Keratocyte cells were pretreated for 60 minutes with 2.5 ng/ml TGF-beta 1. After that, cells were treated with PRGF, AS or with TGF-beta 1 (control). To characterize the proteins deregulated after PRGF and AS treatment, a proteomic approach that combines 1D-SDS-PAGE approach followed by LC-MS/MS was carried out. Results Results show a catalogue of key proteins in close contact with a myofibroblastic differentiated phenotype in AS treated-cells, whereas PRGF-treated cells show attenuation on this phenotype. The number of proteins downregulated after PRGF treatment or upregulated in AS-treated cells suggest a close relationship between AS-treated cells and cytoskeletal functions. On the other hand, proteins upregulated after PRGF-treatment or downregulated in AS-treated cells reveal a greater association with processes such as protein synthesis, proliferation and cellular motility. Conclusion This proteomic analysis helps to understand the molecular events underlying AS and PRGF-driven tissue regeneration processes, providing new evidence that comes along with the modulation of TGF-beta 1 activity and the reversion of the myofibroblastic phenotype by PRGF.This study was fully supported by BTI Biotechnology Institute, a dental implant company that investigates in the fields of oral implantology and PRGF-Endoret technology. MF and FM received a salary as scientists from BTI Biotechnology Institute. EA is the Scientific Director and president of BTI Biotechnology Institute. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Producción de biomasa y extracción de nutrimentos en una plantación de Eucalyptus grandis (Hill ex Maiden) Y Eucalyptus urophylla (S.T. Blake) en ultisoles de México

Objective: Compare biomass production and nutrients accumulation in a plot of Eucalyptus grandis and a plot of Eucalyptus urophylla on four sites of study. Design/methodology/approach: The soils were classified for each site and the biomass productivity in each plantation was evaluated. Soils samples were extracted in each site to determined soil fertility and nutrient uptake by the eucalyptus trees. Results: Site A soil was classified has a Plinthudult, site B was a Rhodudult, site C was a Plinthohumult, and site D was a Paleudult. E. grandis on site C produced lower amount of biomass than sites A, B and D. E. urophylla produced statistically different amount of biomass on each site. Nutrient extraction was statistically lower in sites A and C than in sites B and D. Limitations/implications: Great adaptability to tropical climate and Ultisoils limit the result extrapolation. Findings/Conclusions: Biomass production and nutrient extraction in eucalyptus plantations are directly related to site quality establish in soil classificationObjetivo: Comparar la producción de biomasa y la acumulación de nutrientes en un lote de Eucalyptus grandis y otro de Eucalyptus urophylla en cuatro sitios. Diseño/metodología/aproximación: Se clasificaron los suelos de cada sitio y se evaluó la productividad de biomasa en cada lote. Se extrajeron muestras de suelo en cada sitio para determinar su fertilidad y extracción de nutrientes por parte de los árboles de eucaliptos. Resultados: El suelo del sitio A se clasificó como Plinthudult, del sitio B como un Rhodudult, del sitio C como Plinthohumult, y del sitio D como un Paleudult. E. grandis en el sitio C, produjo menor cantidad de biomasa en comparación con la producción obtenida en los sitios A, B y D. E. urophylla produjo cantidades de biomasa estadísticamente diferentes en cada uno de los sitios. La extracción de N, P, K, Ca y Mg fue estadísticamente menor en los sitios A y C en comparación con los sitios B y D. Limitaciones/implicaciones: La gran capacidad de adaptación del género Eucalyptus a los climas tropicales y a los Ultisoles restringe la extrapolación de los resultados obtenidos. Hallazgos/Conclusiones: La producción de biomasa, así como la extracción de nutrimentos se encuentra relacionada directamente con la calidad del sitio determinado en la clasificación del suelo

Propuesta de práctica sustentable usando un prototipo espectrofotométrico elaborado con materiales electrónicos fáciles de obtener

La formación de profesionales en el área química demanda la necesidad de desarrollar habilidades y criterios experimentales que solo pueden ser cubiertos a través del trabajo en laboratorio. Sin embargo, en la mayoría de los casos se emplean reactivos químicos que, de no ser tratados adecuadamente, tienen un impacto negativo por la generación de desechos tóxicos, además de que se requiere el uso de equipos poco accesibles por su costo. Es por eso que se plantea el desarrollo de una práctica sustentable utilizando extractos de tés verde y negro como reactivos para la determinación espectrofotométrica de hierro mediante la formación de complejos coloreados. Para su medición se propone la construcción y empleo de un dispositivo espectrofotométrico elaborado con materiales accesibles. Los datos obtenidos para la práctica propuesta muestran una buena correlación entre la concentración del analito y la respuesta del instrumento por lo que es factible su implementación