Ocena poziomu wiedzy osób dorosłych na temat resuscytacji krążeniowo : oddechowej (RKO) i użycia automatycznego defibrylatora zewnętrznego (AED) w miejscach publicznych

Wstęp. Wraz z rozwojem cywilizacji, wzrastającym tempem życia, rośnie liczba wypadków i chorób, zwłaszcza chorób układu krążenia. W Polsce średnia liczba zgonów około wypadkowych jest trzy razy wyższa niż średnia europejska. Wiedza na temat pierwszej pomocy jest bardzo ważna wśród społeczeństwa, które stanowi mocny filar niesienia pierwszej pomocy poszkodowanym w nagłych sytuacjach, które są stanami zagrożenia zdrowia i życia. Cel pracy. Celem pracy była ocena i porównanie wiedzy mieszkańców Kielc i Krakowa z zakresu pierwszej pomocy oraz obsługi i zastosowania Automatycznego Defibrylatora Zewnętrznego (AED). Materiał i metody. Grupę badawczą stanowiło 160 osób, z czego 80 osób było z Krakowa, w tym 45 kobiet i 35 mężczyzn i 80 osób z Kielc, w tym 45 kobiet i 35 mężczyzn. Wszyscy re-spondenci byli pełnoletni. W badaniach posłużono się metodą sondażu diagnostycznego bezpośredniego, losowego wykorzys-tując do tego celu narzędzie badawcze w postaci anonimowego kwestionariusza ankiety, opracowanego na bazie Wytycznych Resuscytacji Krążeniowo- Oddechowej 2005 (RKO). Wyniki. Mieszkańcy Krakowa wykazują lepszy poziom wiedzy, aczkolwiek znajomość i obsługa . Respondenci z Krakowa częściej i chętniej uczestniczą w szkoleniach z zakresu BLS-AED i pierwszej pomocy niż respondencki z Kielc. Wnioski. Poziom wiedzy z zakresu udzielania pierwszej pomocy, a przede wszystkim w zakresie resuscytacji krążeniowo - oddechowej i użycia AED przez społeczeństwo z Krakowa i Kielc jest niezadawalający. Istnieje pilna potrzeba wprowadzenia komplementarnego systemu nauczania zagadnień pierwszej pomocy opartego na międzynarodowych standardach, który zagwarantuje odpowiednią jakość edukacji oraz kształtowanie pozytywnych postaw niesienia pomocy, począwszy od wczesnego etapu edukacji szkolnej.Introduction: The number of accidents and diseases, especially cardio-vascular, is increasing along with the develop-ment of civilization and a growing pace of life. In Poland, the average number of accident fatalities is three times higher than the European average. The knowledge of first aid is very im-portant for society, which is a strong pillar of first aid to victims in emergency situations that are dangerous to health and life. The aim of the study: The aim of the study was to assess the knowledge of CPR and first aid in the event of sudden respiratory arrest and cardiac arrest (SCA) and the operation and use of the Automated External Defibrillator (AED). Material and methods: The study group consisted of 160 people, among whom 80 were from Kraków, including 45 women and 35 men and 80 people were from Kielce, including 45 women and 35 men. All the respondents were adults. The method of diagnostic survey was applied in the study. The research instrument was an anonymous survey questionnaire created on the basis of the Car-dio-Pulmonary Resuscitation Guidelines 2005 (CPR). Results: Residents of Kraków have better knowledge of first aid, however the knowledge and operation of the AED among both residents of Kraków and Kielce is inadequate. Respondents from Kraków more often and more willingly participate in BLS-AED and first aid training than respondents from Kielce. Conclusions: The level of knowledge of first aid and especially of Cardio-Pulmonary Resuscitation and the application of the AED is unsatisfactory among residents of Kraków and Kielce. There is an urgent need for a complementary system of first aid instruction which would be based on international standards, and which would ensure an appropriate quality of education and develop a proper attitude among people, starting with the earliest stage of school education

A surface mooring for air–sea interaction research in the Gulf Stream. Part II : analysis of the observations and their accuracies

Author Posting. © American Meteorological Society, 2013. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 39 (2013): 450–469, doi:10.1175/JTECH-D-12-00078.1.A surface mooring was deployed in the Gulf Stream for 15 months to investigate the role of air–sea interaction in mode water formation and other processes. The accuracies of the near-surface meteorological and oceanographic measurements are investigated. In addition, the impacts of these measurement errors on the estimation and study of the air–sea fluxes in the Gulf Stream are discussed. Pre- and postdeployment calibrations together with in situ comparison between shipboard and moored sensors supported the identification of biases due to sensor drifts, sensor electronics, and calibration errors. A postdeployment field study was used to further investigate the performance of the wind sensors. The use of redundant sensor sets not only supported the filling of data gaps but also allowed an examination of the contribution of random errors. Air–sea fluxes were also analyzed and computed from both Coupled Ocean–Atmosphere Response Experiment (COARE) bulk parameterization and using direct covariance measurements. The basic conclusion is that the surface buoy deployed in the Gulf Stream to support air–sea interaction research was successful, providing an improved 15-month record of surface meteorology, upper-ocean variability, and air–sea fluxes with known accuracies. At the same time, the coincident deployment of mean meteorological and turbulent flux sensors proved to be a successful strategy to certify the validity of the bulk formula fluxes over the midrange of wind speeds and to support further work to address the present shortcomings of the bulk formula methods at the low and high wind speeds.The National Science Foundation (Grant OCE04-24536) funded this work, as part of the CLIVAR Mode Water Dynamics Experiment (CLIMODE). The Vetlesen Foundation is also acknowledged for the early support of S. Bigorre.2013-09-0

Trophic consequences of non-native pumpkinseed Lepomis gibbosus for native pond fishes

Introduced non-native fishes can cause considerable adverse impacts on freshwater ecosystems. The pumpkinseed Lepomis gibbosus, a North American centrarchid, is one of the most widely distributed non-native fishes in Europe, having established self-sustaining populations in at least 28 countries, including the U.K. where it is predicted to become invasive under warmer climate conditions. To predict the consequences of increased invasiveness, a field experiment was completed over a summer period using a Control comprising of an assemblage of native fishes of known starting abundance and a Treatment using the same assemblage but with elevated L. gibbosus densities. The trophic consequences of L. gibbosus invasion were assessed with stable isotope analysis and associated metrics including the isotopic niche, measured as standard ellipse area. The isotopic niches of native gudgeon Gobio gobio and roach Rutilus rutilus overlapped substantially with that of non-native L. gibbosus, and were also substantially reduced in size compared to ponds where L. gibbosus were absent. This suggests these native fishes shifted to a more specialized diet in L. gibbosus presence. Both of these native fishes also demonstrated a concomitant and significant reduction in their trophic position in L. gibbosus presence, with a significant decrease also evident in the somatic growth rate and body condition of G. gobio. Thus, there were marked changes detected in the isotopic ecology and growth rates of the native fish in the presence of non-native L. gibbosus. The implications of these results for present and future invaded pond communities are discussed

Selective mGluR1 Antagonist EMQMCM Inhibits the Kainate-Induced Excitotoxicity in Primary Neuronal Cultures and in the Rat Hippocampus

Abundant evidence suggests that indirect inhibitory modulation of glutamatergic transmission, via metabotropic glutamatergic receptors (mGluR), may induce neuroprotection. The present study was designed to determine whether the selective antagonist of mGluR1 (3-ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)-methanone methanesulfonate (EMQMCM), showed neuroprotection against the kainate (KA)-induced excitotoxicity in vitro and in vivo. In in vitro studies on mouse primary cortical and hippocampal neuronal cultures, incubation with KA (150 μM) induced strong degeneration [measured as lactate dehydrogenase (LDH) efflux] and apoptosis (measured as caspase-3 activity). EMQMCM (0.1–100 μM) added 30 min to 6 h after KA, significantly attenuated the KA-induced LDH release and prevented the increase in caspase-3 activity in the cultures. Those effects were dose- and time-dependent. In in vivo studies KA (2.5 nmol/1 μl) was unilaterally injected into the rat dorsal CA1 hippocampal region. Degeneration was calculated by counting surviving neurons in the CA pyramidal layer using stereological methods. It was found that EMQMCM (5–10 nmol/1 μl) injected into the dorsal hippocampus 30 min, 1 h, or 3 h (the higher dose only) after KA significantly prevented the KA-induced neuronal degeneration. In vivo microdialysis studies in rat hippocampus showed that EMQMCM (100 μM) significantly increased γ-aminobutyric acid (GABA) and decreased glutamate release. When perfused simultaneously with KA, EMQMCM substantially increased GABA release and prevented the KA-induced glutamate release. The obtained results indicate that the mGluR1 antagonist, EMQMCM, may exert neuroprotection against excitotoxicity after delayed treatment (30 min to 6 h). The role of enhanced GABAergic transmission in the neuroprotection is postulated

Moving in the anthropocene: global reductions in terrestrial mammalian movements

Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission

Prediction of protein assemblies, the next frontier: The CASP14-CAPRI experiment

We present the results for CAPRI Round 50, the fourth joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of twelve targets, including six dimers, three trimers, and three higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly related templates were found for the individual subunits. Twenty-five CAPRI groups including eight automatic servers submitted ~1250 models per target. Twenty groups including six servers participated in the CAPRI scoring challenge submitted ~190 models per target. The accuracy of the predicted models was evaluated using the classical CAPRI criteria. The prediction performance was measured by a weighted scoring scheme that takes into account the number of models of acceptable quality or higher submitted by each group as part of their five top-ranking models. Compared to the previous CASP-CAPRI challenge, top performing groups submitted such models for a larger fraction (70–75%) of the targets in this Round, but fewer of these models were of high accuracy. Scorer groups achieved stronger performance with more groups submitting correct models for 70–80% of the targets or achieving high accuracy predictions. Servers performed less well in general, except for the MDOCKPP and LZERD servers, who performed on par with human groups. In addition to these results, major advances in methodology are discussed, providing an informative overview of where the prediction of protein assemblies currently stands.Cancer Research UK, Grant/Award Number: FC001003; Changzhou Science and Technology Bureau, Grant/Award Number: CE20200503; Department of Energy and Climate Change, Grant/Award Numbers: DE-AR001213, DE-SC0020400, DE-SC0021303; H2020 European Institute of Innovation and Technology, Grant/Award Numbers: 675728, 777536, 823830; Institut national de recherche en informatique et en automatique (INRIA), Grant/Award Number: Cordi-S; Lietuvos Mokslo Taryba, Grant/Award Numbers: S-MIP-17-60, S-MIP-21-35; Medical Research Council, Grant/Award Number: FC001003; Japan Society for the Promotion of Science KAKENHI, Grant/Award Number: JP19J00950; Ministerio de Ciencia e Innovación, Grant/Award Number: PID2019-110167RB-I00; Narodowe Centrum Nauki, Grant/Award Numbers: UMO-2017/25/B/ST4/01026, UMO-2017/26/M/ST4/00044, UMO-2017/27/B/ST4/00926; National Institute of General Medical Sciences, Grant/Award Numbers: R21GM127952, R35GM118078, RM1135136, T32GM132024; National Institutes of Health, Grant/Award Numbers: R01GM074255, R01GM078221, R01GM093123, R01GM109980, R01GM133840, R01GN123055, R01HL142301, R35GM124952, R35GM136409; National Natural Science Foundation of China, Grant/Award Number: 81603152; National Science Foundation, Grant/Award Numbers: AF1645512, CCF1943008, CMMI1825941, DBI1759277, DBI1759934, DBI1917263, DBI20036350, IIS1763246, MCB1925643; NWO, Grant/Award Number: TOP-PUNT 718.015.001; Wellcome Trust, Grant/Award Number: FC00100

Trophic consequences of an invasive, small-bodied non-native fish, sunbleak Leucaspius delineatus, for native pond fishes

Assessments of the trophic consequences of invasive fishes are important for quantifying their ecological impacts on native species more generally. A small-bodied cyprinid fish native to continental Europe and introduced in the 1970s to the U.K, the sunbleak Leuciscus delineatus, has been shown previously to establish closer social associations with native species of similar size than do native species amongst themselves. To assess the potential detrimental trophic consequences of native species associations with L. delineatus, a field-based experiment was undertaken in summer 2015 in six outdoor, artificial ponds containing three native cyprinid species (rudd Scardinius erthrophthalamus, gudgeon Gobio gobio, tench Tinca tinca). Three ponds were controls (no L. delineatus) and three were treatments (L. delineatus present). The results of stable isotope analysis (SIA) of fish tissue samples provided strong evidence that the isotopic niches of both native benthic fishes were reduced in the presence of L. delineatus, although there were no significant effects on the trophic position, body size or condition of two of the three native fish species. Introduced L. delineatus maintained a core isotopic niche that was distinct from the two native benthic fishes, with no overlap detected between native and non-native fishes when including 40 % and 95% of the data. These results indicate that the response of the native fishes to the introduction of L. delineatus was niche constriction via trophic specialisation, with this response sufficient to maintain their growth rates and condition. This result is similar to studies on a range of small-bodied invasive fishes, suggesting the trophic impacts of these invaders are relatively consistent across species and systems