128 research outputs found
The Frame of Social Media in Academic and Industry
With the development of technology, the communication between people has changed rapidly. Social media is a type of digital network designed to share content with other internet users based on their preferences and associations. The purpose of this research was to understand how industry press and the professional market place frame social media today. Moreover, this research showed the explored current social media pedagogy in business and communication programs to see if it matches the need of industry expectations. This study was a content analysis of the text-based study that uses a qualitative software-Leximancer to analyze data. The result suggested both industry press and the job market expect professionals to understand the skills of how to master the social media platforms, especially Facebook. Finally, universities offer few courses about social media, with primary objective of marketing and communication programs focusing on teaching students to be professional in business and organizations
Experimental behaviour of very high-strength concrete-encased steel composite column subjected to axial compression and end moment
[EN] A type of cost-effective and very high strength concrete (VHSC) with 28-day compressive strength of 100-150 MPa is developed for applications in concrete-encased steel composite column constructions. This paper experimentally investigates the structural behaviour of VHSC encased steel composite columns based on a series of pure compression and eccentric compression tests. It is found that such high-strength composite column exhibits brittle post peak behaviour and low ductility but with acceptable compressive resistance. Throughout the tests, the main failure of VHSC encased column under compressive load is brittle spalling of concrete followed by local buckling of the reinforcement bars. The splitting and slippage may occur between concrete and steel section due to bending downward action. The confinement effect by the shear stirrups designed based on normal reinforced concrete codes may not be sufficient. Composite column subjected to initial flexural cracking due to end moment load with large eccentricity may experience degradation in the stiffness and ultimate resistance so that plastic design resistance may not be achieved. Analytical studies show that the N-M interaction model based on current design codes may over-predict the combined resistance of the composite columns. Therefore, a modified elastic-plastic design approach based on strain compatibility is developed to evaluate the compressive resistance of concrete encased composite columns. The validation against the test data shows a reasonable and conservative estimation on the combined resistance of VHSC encased composite columns.Huang, Z.; Huang, X.; Li, W.; Zhou, Y.; Sui, L.; Liew, JY. (2018). Experimental behaviour of very high-strength concrete-encased steel composite column subjected to axial compression and end moment. En Proceedings of the 12th International Conference on Advances in Steel-Concrete Composite Structures. ASCCS 2018. Editorial Universitat Politècnica de València. 323-329. https://doi.org/10.4995/ASCCS2018.2018.7034OCS32332
A Branch Point of \u3cem\u3eStreptomyces\u3c/em\u3e Sulfur Amino Acid Metabolism Controls the Production of Albomycin
Albomycin (ABM), also known as grisein, is a sulfur-containing metabolite produced by Streptomyces griseus ATCC 700974. Genes predicted to be involved in the biosynthesis of ABM and ABM-like molecules are found in the genomes of other actinomycetes. ABM has potent antibacterial activity, and as a result, many attempts have been made to develop ABM into a drug since the last century. Although the productivity of S. griseus can be increased with random mutagenesis methods, understanding of Streptomyces sulfur amino acid (SAA) metabolism, which supplies a precursor for ABM biosynthesis, could lead to improved and stable production. We previously characterized the gene cluster (abm) in the genome-sequenced S. griseus strain and proposed that the sulfur atom of ABM is derived from either cysteine (Cys) or homocysteine (Hcy). The gene product, AbmD, appears to be an important link between primary and secondary sulfur metabolic pathways. Here, we show that propargylglycine or iron supplementation in growth media increased ABM production by significantly changing the relative concentrations of intracellular Cys and Hcy. An SAA metabolic network of S. griseus was constructed. Pathways toward increasing Hcy were shown to positively impact ABM production. The abmD gene and five genes that increased the Hcy/Cys ratio were assembled downstream of hrdBp promoter sequences and integrated into the chromosome for overexpression. The ABM titer of one engineered strain, SCAK3, in a chemically defined medium was consistently improved to levels ∼400% of the wild type. Finally, we analyzed the production and growth of SCAK3 in shake flasks for further process development
From Clozing to Comprehending: Retrofitting Pre-trained Language Model to Pre-trained Machine Reader
We present Pre-trained Machine Reader (PMR), a novel method to retrofit
Pre-trained Language Models (PLMs) into Machine Reading Comprehension (MRC)
models without acquiring labeled data. PMR is capable of resolving the
discrepancy between model pre-training and downstream fine-tuning of existing
PLMs, and provides a unified solver for tackling various extraction tasks. To
achieve this, we construct a large volume of general-purpose and high-quality
MRC-style training data with the help of Wikipedia hyperlinks and design a Wiki
Anchor Extraction task to guide the MRC-style pre-training process. Although
conceptually simple, PMR is particularly effective in solving extraction tasks
including Extractive Question Answering and Named Entity Recognition, where it
shows tremendous improvements over previous approaches especially under
low-resource settings. Moreover, viewing sequence classification task as a
special case of extraction task in our MRC formulation, PMR is even capable to
extract high-quality rationales to explain the classification process,
providing more explainability of the predictions
Abstract test case prioritization using repeated small-strength level-combination coverage
Abstract—Abstract Test Cases (ATCs) have been widely used in practice, including in combinatorial testing and in software product line testing. When constructing a set of ATCs, due to limited testing resources in practice (for example in regression testing), Test Case Prioritization (TCP) has been proposed to improve the testing quality, aiming at ordering test cases to increase the speed with which faults are detected. One intuitive and extensively studied TCP technique for ATCs is λ-wise Level-combination Coverage based Prioritization (λLCP), a static, black-box prioritization technique that only uses the ATC information to guide the prioritization process. A challenge facing λLCP, however, is the necessity for the selection of the fixed prioritization strength λ before testing — testers need to choose an appropriate λ value before testing begins. Choosing higher λ values may improve the testing effectiveness of λLCP (for example, by finding faults faster), but may reduce the testing efficiency (by incurring additional prioritization costs). Conversely, choosing lower λ values may improve the efficiency, but may also reduce the effectiveness. In this paper, we propose a new family of λLCP techniques, Repeated Small-strength Level-combination Coverage-based Prioritization (RSLCP), that repeatedly achieves the full combination coverage at lower strengths. RSLCP maintains λLCP’s advantages of being static and black box, but avoids the challenge of prioritization strength selection. We performed an empirical study involving five different versions of each of five C programs. Compared with λLCP, and Incremental strength LCP (ILCP), our results show that RSLCP could provide a good trade-off between testing effectiveness and efficiency. Our results also show that RSLCP is more effective and efficient than two popular techniques of Similarity-based Prioritization (SP). In addition, the results of empirical studies also show that RSLCP can remain robust over multiple system releases
Soya saponins and prebiotics alter intestinal functions in Ballan wrasse (Labrus bergylta)
A 5-week feeding trial was conducted in the cleaner fish Ballan wrasse (Labrus bergylta) for a better understanding of the basic biology of the intestinal functions and health in this stomach less species. During the trial, Ballan wrasse was fed either a reference diet, the reference diet supplemented with (i) a commercial prebiotic (Aquate™ SG, 0·4 %) expected to have beneficial effects, (ii) soya saponins (0·7 %) expected to induce inflammation or (iii) a combination of the prebiotics and the soya saponins to find a remedy for gut inflammation. Blood, intestinal tissue and gut content from four consecutive intestinal segments (IN1 – IN4) were collected. No significant differences in fish growth were observed between the four dietary groups. Saponin supplementation, both alone and in combination with prebiotics, increased weight index of IN2 and IN3 and decreased blood plasma glucose, cholesterol and total protein. Dry matter of intestinal content and activity of digestive enzymes were not affected by diet. Histomorphological analyses revealed a progressing inflammation with increased infiltration by immune cells particularly into the distal parts of the intestine in fish fed diets with saponins, both alone and in combination with prebiotics. Gene expression profiles obtained by RNA sequencing and quantitative PCR mirrored the histological and biochemical changes induced by the saponin load. The study demonstrated that Ballan wrasse gut health and digestive function may be markedly affected by feed ingredients containing antinutrients.publishedVersio
Diamagnetic and paramagnetic shifts in self-assembled InAs lateral quantum dot molecules
We uncover the underlying physics that explains the energy shifts of discrete states of individual InAs lateral
quantum dot molecules (LQDMs) as a function of magnetic fields applied in the Faraday geometry. We observe
that ground states of the LQDM exhibit a diamagnetic shift while excited states exhibit a paramagnetic shift.
We explain the physical origin of the transition between these two behaviors by analyzing the molecular exciton
states with effective mass calculations. We find that charge carriers in delocalized molecular states can become
localized in single QDs with increasing magnetic field. We further show that the net effects of broken symmetry
of the molecule and Coulomb correlation lead to the paramagnetic response.NSF
DMR-0844747
DMR 1309989
GV VALi+d Grant
APOSTD/2013/052
NRF of Korea
2011-C0030821/2013R1A1A1007118
MINECO Project
CTQ2011-2732
A Screening Study on Effects Varying Dietary Macronutrient Composition on Gut Functions in Lumpfish (Cyclopterus lumpus)
publishedVersio
Prioritising abstract test cases: an empirical study
Test-case prioritisation (TCP) attempts to schedule the order of test-case execution such that faults can be detected as quickly as possible. TCP has been widely applied in many testing scenarios such as regression testing and fault localisation. Abstract test cases (ATCs) are derived from models of the system under test and have been applied to many testing environments such as model-based testing and combinatorial interaction testing. Although various empirical and analytical comparisons for some ATC prioritisation (ATCP) techniques have been conducted, to the best of the authors' knowledge, no comparative study focusing on the most current techniques has yet been reported. In this study, they investigated 18 ATCP techniques, categorised into four classes. They conducted a comprehensive empirical study to compare 16 of the 18 ATCP techniques in terms of their testing effectiveness and efficiency. They found that different ATCP techniques could be cost-effective in different testing scenarios, allowing us to present recommendations and guidelines for which techniques to use under what conditions. © The Institution of Engineering and Technology 2018
On the selection of strength for fixed-strength interaction coverage based prioritization
Abstract test cases are derived by modeling the system under test, and have been widely applied in practice, such as for software product line testing and combinatorial testing. Abstract test case prioritization (ATCP) is used to prioritize abstract test cases and aims at achieving higher rates of fault detection. Many ATCP algorithms have been proposed, using different prioritization criteria and information. One ATCP approach makes use of fixed-strength level-combinations information covered by abstract test cases, and is called fixed-strength interaction coverage based prioritization (FICBP). Before using FICBP, the prioritization strength λ needs to be decided. Previous studies have generally focused on λ values ranging between 1 and 6. However, no study has investigated the appropriateness of such a range, nor how to assign the prioritization strength for FICBP. To answer these questions, this paper reports on an empirical study involving four real-life programs (each of which with six versions). The experimental results indicate that λ should be set approximately equal to a value corresponding to half of the number of parameters, when testing resources are sufficient. Our results also show that when testing resources are limited or insufficient, either small or large λ values are suggested for FICBP
- …