CLIMA ORGANIZACIONAL: PERCEPÇÃO DOS TAEs DO DEPARTAMENTO DE GESTÃO DE PESSOAS DE UMA IFES

O tema clima organizacional tem sido objeto de grande interesse nos últimos anos, tanto no meio acadêmico como no empresarial. Observou-se que no meio acadêmico o interesse deve-se ao fato de que por meio da análise das diversas dimensões e fatores que compõem o que é denominado clima organizacional, aprofunda-se o estudo sobre o comportamento humano nas organizações. Neste sentido, estudiosos de diversas áreas ocuparam-se da pesquisa sobre o comportamento humano nas organizações, a interação entre indivíduos, causas que impulsionavam ou desestimulavam a realização das atividades, e a influência do fator humano na produtividade e no desempenho organizacional. A proposta desta pesquisa foi mostrar os aspectos relacionados ao clima organizacional na percepção dos servidores públicos do Departamento de Gestão de Pessoas (DGP) da Universidade Federal do Espírito Santo (UFES), sendo o tema de alta relevância para o direito contemporâneo e para a dignidade da pessoa humana no ambiente de trabalho. A preocupação refere-se à valorização das pessoas como um dos elementos mais importantes da estrutura organizacional, razão pela qual surgiu a seguinte indagação: Qual o nível de satisfação dos servidores lotados no Departamento de Gestão de Pessoas, vinculado a Pró-Reitoria de Gestão de Pessoas da UFES? A metodologia utilizada foi a pesquisa descritiva para melhor compreensão do tema pesquisado e as etapas para levantamento das informações foram realizadas em dois momentos, no primeiro momento o levantamento bibliográfico e, no segundo, a aplicação de um questionário de perguntas fechadas e abertas aos servidores públicos do setor, num total de 31 entrevistados. Como conclusão, as análises dos dados sugerem que a maioria dos funcionários apontou como aspecto negativo, em direção à melhora da estrutura fisica do setor, demonstrando por sua vez que, aspectos relacionados a apoio do gestor, reconhecimento e coesão ente os colegas está entre os indicadores de maior satisfação dos entrevistados. A linha de pesquisa do presente estudo se enquadra como Gestão de Operações no Setor Público e, como produto técnico, no caso do mestrado profissional, além de sugestões apresentadas para outras pesquisas, em apêndice, apresenta-se o Relatório Diagnóstico com o Plano de Ação, a ser entregue à UFES, propondo mudanças com relação ao problema percebido, de modo que a organização seja capaz de analisá-lo, ajustá-lo, se necessário, e implementá-lo. Palavras-chaves: Clima Organizacional. RH. Gestão Pública. UFES. Gestão Pessoas

Comparação entre diferentes escores de risco de mortalidade em unidade de tratamento intensivo neonatal

OBJECTIVES: To evaluate and compare birthweight and scores as predictors of neonatal mortality in a Neonatal Intensive Care Unit (NICU). METHODS: The survey included 494 newborns admitted to the neonatal intensive care unit (NICU) of a general hospital in Porto Alegre, southern Brazil, immediately after delivery, between March 1997 and June 1998. Birthweight and scores were evaluated in terms of the variable "death while in NICU". Exclusion criteria were: discharge or death less than 24 hours after admission, admission not immediately following delivery, incomplete study protocol, and congenital malformations incompatible with survival. For CRIB (Clinical Risk Index for Babies) evaluation purposes, only patients born weighing up to 1,500 g were considered. ROC (Receiver Operating Characteristics) curves were calculated for SNAP (Score for Neonatal Acute Physiology) , SNAP-PE (Score for Neonatal Acute Physiology - Perinatal Extension), SNAP II, SNAP-PE II , and CRIB scores, as well as for birthweight. RESULTS: Of the 494 patients studied, 44 died (8.9% mortality). Of the 102 patients born weighing up to 1,500 g, 32 (31.3%) died. The area below the ROC curves ranged from 0.81 to 0.94. There were no statistically significant differences between the areas obtained for all scores evaluated. All mortality risk scores evaluated performed better than birthweight, especially on newborns with birthweight =1,500 g. CONCLUSIONS: All neonatal mortality scores had better performance and were superior to birthweight as measures of in-hospital mortality risk for newborns admitted to NICU.OBJETIVO: Avaliar peso de nascimento e os escores como preditores de mortalidade neonatal em unidade de terapia intensiva neonatal, comparando os seus resultados. MÉTODOS: Foram avaliados 494 recém-nascidos admitidos em uma unidade de terapia intensiva neonatal (UTIN) de um hospital geral de Porto Alegre, RS, logo após o nascimento, entre março de 1997 e junho de 1998. Foram avaliados o peso de nascimento e os escores considerando a variável óbito durante a internação na UTI. Os critérios de exclusão foram: alta ou óbito da UTIN com menos de 24 horas de internação, recém-nascidos cuja internação não ocorreu logo após o nascimento, protocolo de estudo incompleto e malformações congênitas incompatíveis com a vida. Para avaliação do CRIB (Clinical Risk Index for Babies) foram considerados somente os pacientes com peso de nascimento inferior a 1.500 g. Foram calculadas as curvas ROC (Receiver Operating Characteristics Curve) para SNAP (Score for Neonatal Acute), SNAP-PE (Score for Neonatal Acute Physiology Perinatal Extension), SNAP II, SNAP-PE II, CRIB e peso de nascimento. RESULTADOS: Dos 494 pacientes, 44 faleceram (8,9% de mortalidade). Dos 102 recém-nascidos com peso de até 1.500 g, 32 (31,3%) faleceram. As áreas abaixo da curva ROC variaram de 0,81 a 0,94. Todos os escores avaliados mostraram áreas abaixo da curva ROC sem diferenças estatisticamente significativas. Os escores de risco de mortalidade estudados apresentaram um melhor desempenho que o peso de nascimento, especialmente em recém-nascidos com peso de nascimento igual ou menor que 1.500 g. CONCLUSÕES: Todos os escores de mortalidade neonatal apresentaram melhor desempenho e foram superiores ao peso de nascimento como medidores de risco de óbito hospitalar para recém-nascidos internados em UTIN

Convolutamydine A and synthetic analogues have antinociceptive properties in mice

AbstractConvolutamydine A, an oxindole that originated from a marine bryozoan, has several biological effects. In this study, we aimed to investigate the antinociceptive effects of convolutamydine A and two new synthetic analogues.Convolutamydine A and the two analogues were given orally to assess their ability to induce antinociceptive effects. Formalin-induced licking response, acetic acid-induced contortions, and hot plate models were used to characterize the effects of convolutamydine A and its analogues.Convolutamydine A (4,6-bromo-3-(2-oxopropyl)-3-hydroxy-2-oxindole), compound 1 (3-(2-oxopropyl)-3-hydroxy-2-oxindole), and compound 2 (5-bromo-3-(2-oxopropyl)-3-hydroxy-2-oxindole) caused peripheral antinociceptive and anti-inflammatory effects in the acetic acid-induced contortions and the formalin-induced licking models. Supraspinal effects were also observed in the hot plate model and were similar to those obtained with morphine. The peripheral effects were not mediated by the cholinergic or opioid systems. The antinociceptive effects of convolutamydine A seem to be mediated by all three systems (cholinergic, opioid, and nitric oxide systems), and the mechanism of action of compounds 1 and 2 involved cholinergic and nitric oxide-mediated mechanisms. Convolutamydine A and its analogues (compounds 1 and 2) showed good antinociceptive ability after systemic administration in acute pain models. The antinociceptive action mediated by cholinergic, opioid, and nitric oxide systems could explain why convolutamydine A, compound 1, and compound 2 retained their antinociceptive effects. The doses used were similar to the doses of morphine and were much lower than that of acetylsalicylic acid, the classical analgesic and anti-inflammatory drug.In conclusion, convolutamydine A and the two analogues demonstrated antinociceptive effects comparable to morphine's effects

Growth study of indium-catalyzed silicon nanowires by plasma enhanced chemical vapor deposition

Indium was used as a catalyst for the synthesis of silicon nanowires in a plasma enhanced chemical vapor deposition reactor. In order to foster the catalytic activity of indium, the indium droplets had to be exposed to a hydrogen plasma prior to nanowire growth in a silane plasma. The structure of the nanowires was investigated as a function of the growth conditions by electron microscopy and Raman spectroscopy. The nanowires were found to crystallize along the , or growth direction. When growing on the and directions, they revealed a similar crystal quality and the presence of a high density of twins along the {111} planes. The high density and periodicity of these twins lead to the formation of hexagonal domains inside the cubic structure. The corresponding Raman signature was found to be a peak at 495 cm−1, in agreement with previous studies. Finally, electron energy loss spectroscopy indicates an occasional migration of indium during growt

DEVELOPMENT OF A BURGER FORMULATION WITH PIZZA AROMA IN A PACKAGING SYSTEM TYPE IN COOK

The market of meat processed products, including hamburgers, grows up every year and consumers demand quality and convenience.  The objective of this study was to prepare a hamburger with chicken meat, making use of the chicken meat cuts that are considered more noble such as chicken breast and thigh, source of unsaturated fatty acids, in packaging cook in. The formulation was defined based on market survey and testing in a pilot plant through various modifications of the formulation, seeking the care of sensory patterns, a chicken burger formula with 50.0 % breast and 23.0 % thigh, added aroma identical to pizza, provolone cheese and ground dried tomato was used in the tests and its physicochemical, microbiological and sensorial analysis. Physicochemical, microbiological and sensorial analysis was carried out of this burgues. The samples were tested by 53 tasters without training, through affective hedonic scale of 5 points. The physicochemical analyses indicated the following contents: moisture 62.42 %, proteins 16.00 %, lipids 15.25 %, fiber 1.83 % and sodium chloride 1.90 %, all of which meet the requirements of Brazilian legislation. The sensorial analysis indicated excellent acceptance of the product, with an average score of 4.44, classifying it as “like it moderately” and “like it very much.” Thus, the product developed has great potential for dissemination in the consumer market as well as being innovative by using a packaging type bakes easy that allows for adding value and differentiation for consumers seeking sensuousness and practicality in your meals

Optical study of the band structure of wurtzite GaP nanowires

We investigated the optical properties of wurtzite (WZ) GaP nanowires by performing photoluminescence (PL) and time-resolved PL measurements in the temperature range from 4 K to 300 K, together with atom probe tomography to identify residual impurities in the nanowires. At low temperature, the WZ GaP luminescence shows donor-acceptor pair emission at 2.115 eV and 2.088 eV, and Burstein-Moss band-filling continuum between 2.180 and 2.253 eV, resulting in a direct band gap above 2.170 eV. Sharp exciton α-β-γ lines are observed at 2.140-2.164-2.252 eV, respectively, showing clear differences in lifetime, presence of phonon replicas, and temperature- dependence. The excitonic nature of those peaks is critically discussed, leading to a direct band gap o

Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma

HOXA genes encode critical transcriptional regulators of embryonic development that have been implicated in cancer. In this study, we documented functional relevance and mechanism of activation of HOXA9 in glioblastoma (GBM), the most common malignant brain tumor. Expression of HOXA genes was investigated using reverse transcription-PCR in primary gliomas and glioblastoma cell lines and was validated in two sets of expression array data. In a subset of GBM, HOXA genes are aberrently activated within confined chromosomal domains. Transcriptional activation of the HOXA cluster was reversible by a phosphoinostide 3-kinase (PI3K) inhibitor through an epigenetic mechanism involving histone H3K27 trimethylation. Functional studies of HOXA9 showed its capacity to decrease apoptosis and increase cellular proliferation along with tumor necrosis factor-related apoptosis-including ligand resistance. Notably, aberrant expression of HOXA9 was independently predictive of shorter overall and progression-free survival in two GBM patient sets and improved survival prediction by MGMT promoter methylation. Thus, HOXA9 activation is a novel, independent, and negative prognostic marker in GBM that is reversible through a PI3K-associated epigenetic mechanism. Our findings suggest a transcriptional pathway through which PI3K activates oncogenic HOXA expression with implications for mTOR or PI3K targeted therapies.NIH grants NIH CA094971 (J.F. Costello) and NIH/NCI F32 CA113039-01 (J.S. Smith); Karen Osney Brownstein Endowed Chair (J.F. Costello); UC Discovery grant Bio05-10501 (J.F. Costello and H.S. Phillips); Portuguese Science and Technology Foundation SFRH/BD/15258/2004 (B.M. Costa); and Luso-American Development Foundation, Portugal 186/06 (B.M. Costa

Local modification of GaAs nanowires induced by laser heating

GaAs nanowires were heated locally under ambient air conditions by a focused laser beam which led to oxidation and formation of crystalline arsenic on the nanowire surface. Atomic force microscopy, photoluminescence and Raman spectroscopy experiments were performed on the same single GaAs nanowires in order to correlate their structural and optical properties. We show that the local changes of the nanowires act as a barrier for thermal transport which is of interest for thermoelectric applications

Effect of the GaAsP shell on optical properties of self-catalyzed GaAs nanowires grown on silicon

We realize growth of self-catalyzed core-shell GaAs/GaAsP nanowires (NWs) on Si substrates using molecular-beam epitaxy. Transmission electron microscopy (TEM) of single GaAs/GaAsP NWs confirms their high crystal quality and shows domination of the zinc-blende phase. This is further confirmed in optics of single NWs, studied using cw and time-resolved photoluminescence (PL). A detailed comparison with uncapped GaAs NWs emphasizes the effect of the GaAsP capping in suppressing the non-radiative surface states: significant PL enhancement in the core-shell structures exceeding 2000 times at 10K is observed; in uncapped NWs PL is quenched at 60K whereas single core-shell GaAs/GaAsP NWs exhibit bright emission even at room temperature. From analysis of the PL temperature dependence in both types of NW we are able to determine the main carrier escape mechanisms leading to the PL quench