Análisis normativo de un territorio “Pueblito Tolimense”

El Pueblito Tolimense es una configuración cultural urbano-arquitectónica la cual se entiende a través de la identidad de sus pobladores y artificios culturales, los cuales han sido establecidos con el fin de conservar las diferentes tradiciones y costumbres típicas del Pueblito Tolimense, por lo tanto se realizará el análisis normativo – Acuerdo 009 de (2009), Decreto Municipal 1000-0672 de (2013) y el Decreto Municipal 1000-0668 de (2014). En consecuencia, este análisis se realiza, debido a la relevancia que tiene este territorio de la ciudad, siendo un espacio instituido a partir de una normativa urbanística y arquitectónica, la cual no ha sido desarrollada a la fecha

Mujeres en la arqueología de Mendoza: Pioneras, silencios y nuevas voces

This preliminary article arose from the interest of a group of women archaeologists from different parts of the Province of Mendoza (Argentina) who met with the aim of generating a new perspective on the place of women in the local history of the discipline. This vision, based on their own accounts, makes it possible to highlight, rethink, and question this history and clarify the current situation. To address this issue, we worked on three areas of analysis. The first focuses on recognizing the trajectories of women pioneers and finding evidence of them in the history of archaeology in Mendoza. The second area analyzes the professional disparity between men and women within the discipline. The third area investigates the types of violence in the professional and academic environment. The results show the historical invisibility of pioneer women archaeologists in the province between the 1940s and 1970s. It was also possible to recognize the disparity and professional segregation between women and men in the field of teaching and research, where women achieve less progress in professional careers. Finally, we describe concrete actions of gender violence experienced by women archaeologists today, which reveals the internalization of the mechanisms of patriarchal coercion within the academic system.  Este trabajo, de carácter preliminar, surgió del interés de un grupo de arqueólogas de diferentes regiones de la Provincia de Mendoza (Argentina) reunidas con el objetivo de generar una nueva mirada acerca del lugar de las mujeres en la historia local de la disciplina. Esta visión basada en relatos propios permitió evidenciar, repensar y cuestionar esta historia y seguidamente exponer la situación actual. Para abordar esta problemática se trabajó en el análisis de tres ejes. El primero, se centró en reconocer las trayectorias de las pioneras y evidenciar su presencia en la historia de la arqueología en Mendoza; el segundo eje analizó la existencia de disparidad profesional entre varones y mujeres dentro de la disciplina; el tercero indagó sobre los tipos de violencia ejercida en el ámbito profesional y académico. Los resultados demuestran la invisibilización histórica que han tenido las mujeres pioneras de la disciplina en la provincia entre las décadas de 1940 y 1970. También pudo reconocerse la disparidad y segregación profesional entre mujeres y varones en el ámbito de la docencia y la investigación, en la que las mujeres logran menores avances en la carrera profesional. Por último, se pusieron de manifiesto las acciones concretas de violencia de género experimentadas por las arqueólogas en la actualidad, que dan cuenta de la interiorización de los mecanismos de coerción del patriarcado dentro del sistema académico.

Women in the archaeology of Mendoza: pioneers, silences and new voices

Este trabajo, de carácter preliminar, surgió del interés de un grupo de arqueólogasi de diferentes regiones de la Provincia de Mendoza (Argentina) reunidas con el objetivo de generar una nueva mirada acerca del lugar de las mujeres en la historia local de la disciplina. Esta visión basada en relatos propios permitió evidenciar, repensar y cuestionar esta historia y seguidamente exponer la situación actual. Para abordar esta problemática se trabajó en el análisis de tres ejes. El primero, se centró en reconocer las trayectorias de las pioneras y evidenciar su presencia en la historia de la arqueología en Mendoza; el segundo eje analizó la existencia de disparidad profesional entre varones y mujeres dentro de la disciplina; el tercero indagó sobre los tipos de violencia ejercida en el ámbito profesional y académico. Los resultados demuestran la invisibilización histórica que han tenido las mujeres pioneras de la disciplina en la provincia entre las décadas de 1940 y 1970. También pudo reconocerse la disparidad y segregación profesional entre mujeres y varones en el ámbito de la docencia y la investigación, en la que las mujeres logran menores avances en la carrera profesional. Por último, se pusieron de manifiesto las acciones concretas de violencia de género experimentadas por las arqueólogas en la actualidad, que dan cuenta de la interiorización de los mecanismos de coerción del patriarcado dentro del sistema académico.This preliminary article arose from the interest of a group of women archaeologists from different parts of the Province of Mendoza (Argentina) who met with the aim of generating a new perspective on the place of women in the local history of the discipline. This vision, based on their own accounts, makes it possible to highlight, rethink, and question this history and clarify the current situation. To address this issue, we worked on three areas of analysis. The first focuses on recognizing the trajectories of women pioneers and finding evidence of them in the history of archaeology in Mendoza. The second area analyzes the professional disparity between men and women within the discipline. The third area investigates the types of violence in the professional and academic environment. The results show the historical invisibility of pioneer women archaeologists in the province between the 1940s and 1970s. It was also possible to recognize the disparity and professional segregation between women and men in the field of teaching and research, where women achieve less progress in professional careers. Finally, we describe concrete actions of gender violence experienced by women archaeologists today, which reveals the internalization of the mechanisms of patriarchal coercion within the academic system.Fil: Puebla, Lorena. Universidad Nacional de Cuyo. Facultad de Filosofía y Letras. Instituto de Arqueología y Etnología; ArgentinaFil: Prieto Olavarría, Cristina Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Argentino de Nivología, Glaciología y Ciencias Ambientales. Provincia de Mendoza. Instituto Argentino de Nivología, Glaciología y Ciencias Ambientales. Universidad Nacional de Cuyo. Instituto Argentino de Nivología, Glaciología y Ciencias Ambientales; ArgentinaFil: Frigolé, Cecilia Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Interdisciplinario de Ciencias Básicas. - Universidad Nacional de Cuyo. Instituto Interdisciplinario de Ciencias Básicas; ArgentinaFil: Guevara Batllori, María Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mendoza. Museo de Ciencias Naturales y Antropológicas J. Cornelio Moyano; ArgentinaFil: Salgán, María Laura. Universidad Tecnologica Nacional. Facultad Reg.san Rafael. Instituto de Evolucion, Ecologia Historica y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Mendoza. Instituto de Evolucion, Ecologia Historica y Ambiente.; ArgentinaFil: María Sol, Zárate Bernardi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Interdisciplinario de Ciencias Básicas. - Universidad Nacional de Cuyo. Instituto Interdisciplinario de Ciencias Básicas; ArgentinaFil: Pompei, María de la Paz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Estudios Sociales. Universidad Nacional de Tucumán. Instituto Superior de Estudios Sociales; ArgentinaFil: Da Peña Aldao, Gabriela Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mendoza. Museo de Ciencias Naturales y Antropológicas J. Cornelio Moyano; ArgentinaFil: Yebra, Lucía Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto Interdisciplinario de Ciencias Básicas. - Universidad Nacional de Cuyo. Instituto Interdisciplinario de Ciencias Básicas; ArgentinaFil: Sugrañes, Nuria Andrea. Universidad Tecnologica Nacional. Facultad Reg.san Rafael. Instituto de Evolucion, Ecologia Historica y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Mendoza. Instituto de Evolucion, Ecologia Historica y Ambiente.; ArgentinaFil: Albarrán, Elina. Gobierno de Mendoza. Ministerio de Cultura y Turismo. Dirección de Patrimonio Cultural y Museos. Área de Arqueología y Paleontología; Argentin

Experiencia vivencial: Elaboración de documental “Torres de San Borja” en el marco del Proyecto Uniones

Resumen El presente documento describe los detalles de la realización del documental “Torres de San Borja”, cuya finalidad es crear conciencia sobre las dificultades que enfrenta el asentamiento humano del mismo nombre y alentar al apoyo de esta comunidad mediante la Responsabilidad Social. Para ello se realizaron visitas a la zona de intervención buscando familias dispuestas a ser entrevistadas, estas entrevistas fueron grabadas y editadas en formato documental con la intención de que sea proyectada públicamente y frente a los protagonistas del documental. Estas actividades se llevaron a cabo exitosamente congregando a 59 personas en total.Abstract This document describes the details of the documentary film "Torres de San Borja", whose purpose is to raise awareness of the difficulties faced by the human settlement with the same name and to encourage the support of this community through social responsibility. To do this, we have to visit the intervention area, looking for families who wants to support us with the interviews, these interviews were recorded and edited in a documentary format with the intention of being projected openly and in front of the protagonists of the documentary. These activities were successfully carried out with 59 participants

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Geographic patterns of tree dispersal modes in Amazonia and their ecological correlates

Aim: To investigate the geographic patterns and ecological correlates in the geographic distribution of the most common tree dispersal modes in Amazonia (endozoochory, synzoochory, anemochory and hydrochory). We examined if the proportional abundance of these dispersal modes could be explained by the availability of dispersal agents (disperser-availability hypothesis) and/or the availability of resources for constructing zoochorous fruits (resource-availability hypothesis). Time period: Tree-inventory plots established between 1934 and 2019. Major taxa studied: Trees with a diameter at breast height (DBH) ≥ 9.55 cm. Location: Amazonia, here defined as the lowland rain forests of the Amazon River basin and the Guiana Shield. Methods: We assigned dispersal modes to a total of 5433 species and morphospecies within 1877 tree-inventory plots across terra-firme, seasonally flooded, and permanently flooded forests. We investigated geographic patterns in the proportional abundance of dispersal modes. We performed an abundance-weighted mean pairwise distance (MPD) test and fit generalized linear models (GLMs) to explain the geographic distribution of dispersal modes. Results: Anemochory was significantly, positively associated with mean annual wind speed, and hydrochory was significantly higher in flooded forests. Dispersal modes did not consistently show significant associations with the availability of resources for constructing zoochorous fruits. A lower dissimilarity in dispersal modes, resulting from a higher dominance of endozoochory, occurred in terra-firme forests (excluding podzols) compared to flooded forests. Main conclusions: The disperser-availability hypothesis was well supported for abiotic dispersal modes (anemochory and hydrochory). The availability of resources for constructing zoochorous fruits seems an unlikely explanation for the distribution of dispersal modes in Amazonia. The association between frugivores and the proportional abundance of zoochory requires further research, as tree recruitment not only depends on dispersal vectors but also on conditions that favour or limit seedling recruitment across forest types

Development of a Novel Scaffold of Chitosan, Type IV Collagen and Integrin α3β1 As Alternative Scaffold for Primary Culture of Podocytes

Loss of podocytes has been a main pathology present in renal diseases; the leak of these specialized cells increases the permeability of the glomerular basal membrane (GMB) and protein release affecting the glomeruli, the main structure of the kidney. The study of different physiopathology mechanism has been a challenge because of the short lifetime of podocytes in vitro. We obtained and characterized composites based on Chitosan (CTS), polyvinyl alcohol (PVA), type IV collagen and integrin &alpha;3&beta;1 as a possible application in primary culture of podocytes. Podocytes were extracted from the urine of patients with Idiopathic Nephrotic Syndrome (INS). To evaluate biocompatibility, we assessed cell viability through the lactate dehydrogenase assay. Immunohistochemical staining was used to detect the expression of specific proteins from podocytes such as podocin, and podocalyxin and CD80, a marker of cellular stress. The results showed that our synthesis method promotes the copolymerization of the components in the scaffold. Due to its reactivity, the amine group of chitosan made links with type IV collagen and integrin &alpha;3&beta;1. The swelling and degradation tests allowed us to select the material with the best mechanical properties for cellular culture. The expression of podocin and podocalyxin remains the same in the culture of podocytes on the scaffold; in contrast, CD80 expression increased. The viability of podocytes cultured on the CTS/PVA/type IV collagen/integrin &alpha;3&beta;1 scaffold increased in comparison to the culture control

Vivential experience: “Torres de San Borja” a documentary film production in frame of Uniones Project

Resumen El presente documento describe los detalles de la realización del documental “Torres de San Borja”, cuya finalidad es crear conciencia sobre las dificultades que enfrenta el asentamiento humano del mismo nombre y alentar al apoyo de esta comunidad mediante la Responsabilidad Social. Para ello se realizaron visitas a la zona de intervención buscando familias dispuestas a ser entrevistadas, estas entrevistas fueron grabadas y editadas en formato documental con la intención de que sea proyectada públicamente y frente a los protagonistas del documental. Estas actividades se llevaron a cabo exitosamente congregando a 59 personas en total.Abstract This document describes the details of the documentary film "Torres de San Borja", whose purpose is to raise awareness of the difficulties faced by the human settlement with the same name and to encourage the support of this community through social responsibility. To do this, we have to visit the intervention area, looking for families who wants to support us with the interviews, these interviews were recorded and edited in a documentary format with the intention of being projected openly and in front of the protagonists of the documentary. These activities were successfully carried out with 59 participants

Hospital padrino: a collaborative strategy model to tackle maternal mortality: a mixed methods study in a middle-income regionResearch in context

Summary: Background: Reducing maternal mortality ratio (MMR) remains a paramount goal for low- and middle-income countries (LMICs), especially after COVID-19’s devastating impact on maternal health indicators. We describe our experience implementing the Hospital Padrino Strategy (HPS), a collaborative model between a high-complexity hospital (Fundación Valle del Lili) and 43 medium- and low-complexity hospitals in one Colombian department (an administrative and territorial division) from 2021 to 2022, to sustain the trend towards reducing MMR. The study aimed to assess the effects of implementing HPS on both hospital performance and maternal health indicators in Valle del Cauca department (VCD). Methods: A mixed-methods study was conducted, comprising two phases. In the first phase, we investigated a cohort of hospitals through prospective follow-up to assess the outcomes of HPS implementation on hospital performance and maternal health indicators in VCD. In the second phase, qualitative data were collected through focus groups with 131 health workers from 33 hospitals to explore the implications of the HPS implementation on healthcare personnel. All data were obtained from records within the HPS implementation and from the Health Secretary of VCD. Findings: Evidence shows that in the context of HPS, 51 workshops involved 980 healthcare workers, covering the entire territory. Substantial improvements were observed in hospital conditions and healthcare personnel’s technical competencies when providing obstetric care. Seven hundred eighty-five pregnant women with obstetric or perinatal emergencies received care through telehealth systems, with a progressive increase in technology adoption. Nine percent required Intensive Care Unit (ICU) admission, and none died. The MMR decreased from 78.8 in 2021 to 12.0 cases per 100,000 live births by 2022. Improvements in indicators and conducted training sessions instilled confidence and empowerment among the healthcare teams in the sponsored hospitals, as evidenced in focus groups derived from a sample of 131 healthcare workers from 33 hospitals. Interpretation: Implementing the Hospital Padrino Strategy led to a significant MMR reduction, and consolidated a model of social healthcare innovation replicable in LMICs. Funding: The Hospital Padrino Strategy was funded by the Fundación Valle del Lili and the Health Secretary of Valle del Cauca. Furthermore, this study received funding from a general grant for research from Tecnoquimicas S.A