16 research outputs found
Shoreward Intrusion of Upper Gulf Stream Water onto the United States Southeastern Continental Shelf
- Publication venue
- ODU Digital Commons
- Publication date
- 01/01/1987
- Field of study
In winter, cooling of the South Atlantic Bight continental shelf water results in higher density in the middle shelf region relative to the shelf-break region where the western flank of the Gulf Stream flows. Shoreward, estuarine-like intrusion of the upper Gulf Stream water in the presence of such a positive onshore density gradient is then possible through advective processes triggered either by the meander of the Stream or onshore Ekman transports by southward wind stresses. Repeated cross-shelf hydrographic transects were conducted from 10 January through 30 January 1986 to more closely study this intrusion process. These observations show many features predicted by a previous numerical model study. A semi-empirical model is proposed here wherein the state of stratification of water on the outer continental shelf region just inshore of the shelf break is used as an indicator of the intrusion process. Model analysis suggests correlating the observed time rate of change of potential energy of the water column with wind-induced cross-shelf Ekman transport. The correlation fit is good for at least half of the data set, suggesting that wind-induced intrusion was significant during the observations. The analysis also suggests that it is possible to distinguish intrusion processes which are wind induced from those which are induced by Gulf Stream meanders. Both observations and the previous numerical model study show transient shelf-break upwelling following a southward wind impulse. A simplified model suggests that the upwelling is a result of a cyclonic vortex, bounded at the shelf break, produced by interaction of wind stress and sloping bottom topography. Transient upwellings introduce Gulf Stream water from below the mixed layer to the sea surface, where it is transported onshore to the continental shelf by intrusion processes. This provides a mechanism by which nutrient-rich, deeper Gulf Stream water can replenish the water mass of the adjacent continental shelf
Palladium-coated and bare copper wire study for ultra-fine pitch wire bonding
- Publication venue
- 'The Electrochemical Society'
- Publication date
- 01/01/2013
- Field of study
There is growing interest in copper (Cu) wire bonding due to its significant cost savings over gold wire. However, concerns on corrosion susceptibility and package reliability have driven the industry to develop alternative materials. Recently, palladium-coated copper (PdCu) wire has become widely used as it is believed to improve reliability. In this paper, we experimented with 0.6 mil PdCu and bare Cu wires. Palladium distribution and grain structure of the PdCu Free Air Ball (FAB) were investigated. It was observed that Electronic Flame Off (EFO) current and the cover gas type have a significant effect on palladium distribution. The Free Air Ball (FAB) hardness was measured and correlated to palladium distribution and grain structure. First bond process responses were characterized. The impact of palladium on wire bondability and wire bond intermetallic using a high temperature storage test was studied. These results for PdCu wire were compared with bare Cu wire.Published versio
Patients with Crohn's disease have longer post-operative in-hospital stay than patients with colon cancer but no difference in complications' rate
- Author
- Abraham Nordling M
- Abrisqueta J
- Achkasov S
- Agalianos C
- Agarwal T
- Agha A
- Aguilar Teixido F
- Aguiló Lucia J
- Ahlberg M
- Ahmed J
- Ais G
- Aiupov R
- Akhtar M
- Akmalov Y
- Akrida I
- Al Naimi N
- Al Qaddo A
- Alam N
- Alcantara Moral M
- Alcazar Montero J
- Aldrey Cao I
- Aleksic A
- Ali G
- Aliev I
- Allan S
- Almeida A
- Alonso Gonçalves S
- Alonso J
- Alonso N
- Alos Company R
- Alvarez Gallego M
- Amado S
- Ambrona Zafra D
- Amilka Ayala B
- Amin A
- Amore Bonapasta S
- Amstrup Funder J
- Ancans G
- Andreani S
- Andrews E
- Angelov K
- Angoso Clavijo M
- Angrima I
- Annecchiarico M
- Antonio Gracia Solanas J
- Antos F
- Arabadjieva E
- Arces F
- Arenal J
- Arencibia B
- Argentou M
- Arias Pacheco R
- Arias F
- Arnold S
- Arredondo Chaves J
- Arron M
- Arthur J
- Artioukh D
- Arya S
- Aryal K
- Aslam M
- Asteria Cr
- Atladottir J
- Avital S
- Awad F
- Ayaani S
- Aytac B
- Bacchelli C
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- Bains S
- Baixauli Fons J
- Bajwa A
- Balaguer Ojo C
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- Balfour A
- Baral J
- Barben C
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- Bardini R
- Bargallo Berzosa J
- Barisic G
- Barker J
- Basso L
- Battersby N
- Battersby N
- Batzalexis K
- Belgers E
- Bell A
- Belli A
- Bellomo R
- Bemelman W
- Bemelman W
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- Besznyák I
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- Buhr J
- Bulanov D
- Bursics A
- Buskens C
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- Wai Ho C
- Walega P
- Walker K
- Wang X
- Warner M
- Warusavitarne J
- Wassenaar E
- Wasserberg N
- Watson A
- Watson N
- Watson R
- Weaver H
- Weerts J
- Weindl I
- Weixler B
- White I
- Williams G
- Williams G
- Williams M
- Wilson J
- Winter D
- Wojciech W
- Wolthuis A
- Wrafter P
- Yamamoto T
- Yauw S
- Yeung J
- Yilmazlar T
- Yonkov A
- Yousefi P
- Yuksel O
- Zafirov G
- Zambrano Muñoz R
- Zammit M
- Zapolskiy A
- Zawadzki M
- Zerpa Martin C
- Zimmerman D
- Zmora O
- Zmora O
- Álvarez Conde J
- Álvarez Laso C
- Örhalmi J
- Øresland T
- Švagždys S
- Publication venue
- 'Baishideng Publishing Group Inc.'
- Publication date
- 01/01/2019
- Field of study
BACKGROUNDRight hemicolectomy or ileocecal resection are used to treat benign conditions like Crohn's disease (CD) and malignant ones like colon cancer (CC).AIMTo investigate differences in pre- and peri-operative factors and their impact on post-operative outcome in patients with CC and CD.METHODSThis is a sub-group analysis of the European Society of Coloproctology's prospective, multi-centre snapshot audit. Adult patients with CC and CD undergoing right hemicolectomy or ileocecal resection were included. Primary outcome measure was 30-d post-operative complications. Secondary outcome measures were post-operative length of stay (LOS) at and readmission.RESULTSThree hundred and seventy-five patients with CD and 2,515 patients with CC were included. Patients with CD were younger (median = 37 years for CD and 71 years for CC (P < 0.01), had lower American Society of Anesthesiology score (ASA) grade (P < 0.01) and less comorbidity (P < 0.01), but were more likely to be current smokers (P < 0.01). Patients with CD were more frequently operated on by colorectal surgeons (P < 0.01) and frequently underwent ileocecal resection (P < 0.01) with higher rate of de-functioning/primary stoma construction (P < 0.01). Thirty-day post-operative mortality occurred exclusively in the CC group (66/2515, 2.3%). In multivariate analyses, the risk of post-operative complications was similar in the two groups (OR 0.80, 95%CI: 0.54-1.17; P = 0.25). Patients with CD had a significantly longer LOS (Geometric mean 0.87, 95%CI: 0.79-0.95; P < 0.01). There was no difference in re-admission rates. The audit did not collect data on post-operative enhanced recovery protocols that are implemented in the different participating centers.CONCLUSIONPatients with CD were younger, with lower ASA grade, less comorbidity, operated on by experienced surgeons and underwent less radical resection but had a longer LOS than patients with CC although complication's rate was not different between the two groups
Innovative approaches for induction of gastrointestinal anastomotic healing: an update on experimental and clinical aspects
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- A Caziuc
- A Dalvi
- A Karliczek
- A Lavrentieva
- A Modasi
- AA Slesser
- AD Fajardo
- AN Morks
- AS Neish
- BD Shogan
- C Perez-Jorge
- CA Ford
- CE Graves
- CF Bellows
- D Pantelis
- D Van de Putte
- D Vilhjalmsson
- E Rijcken
- EC Consten
- FD McDermott
- FD Sabino
- FG Wang
- G Portillo
- GA Markides
- H Matras
- H Pan
- HC Pommergaard
- HC Pommergaard
- HP Jiang
- I Baloyiannis
- IS Bakker
- J Chen
- JB Murphy
- JC Alverdy
- JC Slieker
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- JD Beard
- JM Suarez-Grau
- K Albanopoulos
- K Shigeta
- K Shinagawa
- KA Forde
- KA Miller
- KA Vakalopoulos
- KE Rollins
- L Marano
- L Xiao
- M Aly
- M Honda
- M Koullouros
- M Nerstrøm
- MA Sugimoto
- ME Franklin Jr
- ME Franklin Jr
- MM El-Said
- MN Oines
- MS Agren
- N Huser
- N Komen
- O Kaidar-Person
- P Sukho
- PA Neumann
- PM Castro
- PM Krarup
- Q Wang
- R Aggarwal
- R Madani
- RA Fischl
- RJ Brouwer
- S Gaines
- S Hajibandeh
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- S Wang
- SR Markar
- ST McSorley
- ST Yauw
- SW Wu
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- V Alvarenga Jr
- V Fattori
- WF Seifert
- WL Gu
- WS Tan
- WT Zhao
- Y Maruya
- Y Yang
- Z Li
- Z Wu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Production, properties, and industrial uses of magnesium and its alloys
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- 'Minerals Yearbook'
- 'Press cast process for magnesium'
- Aamland E.
- Andreev A. E.
- Barranik I. A.
- Bauer A.
- Bauer A. F.
- Bennett F. C.
- Bolstad J. A.
- Boltenkov I. F.
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- Dritz M. E.
- Fisher P. A.
- Fisher P. A.
- Fisher P. A.
- Fisher P. A.
- Fisher P. A.
- Foerster G.
- Foerster G.
- Foerster G. S.
- Fowler G. A.
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- Lebedev O. A.
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- Ryazantsev V.I.
- Safranek W. H.
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- Spencer L. F.
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- Street A.
- Udell R. F.
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- Valley R. Z.
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- Vyatkin I. P.
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- Vyatkin I. P.
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- Williams J.
- Winterhager H.
- Ya E.
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- Yauw A. E.
- Zuev N. M.
- Zuev N. M.
- Publication venue
- 'Maney Publishing'
- Publication date
- Field of study
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
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- 6zkan Bb
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- Harrison Plm
- Hartley J
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- Winarski A
- Wing Vc
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- Yildiz T
- Yilmaz I
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- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
AIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
- Author
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
- Abid A
- Abid H
- Abrisqueta Carrion J
- Abuhussein N
- Abul Mh
- Acar S
- Acherman Yiz
- Acquaah F
- Acres M
- Adams R
- Adams Rd
- Adebayo Aa
- Adeleja I
- Adiyaman C
- Adjei H
- Adlan A
- Afzal Z
- Agalar C
- Agarwal V
- Agrawal M
- Ahern N
- Ahmad A
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahn Js
- Aidoo-Micah Ge
- Aildasani L
- Aithie Jm
- Akbulut F
- Akcaoglu T
- Akdogan A
- Akhtar S
- Akkaya E
- Akkucuk S
- Akpunarli B
- Aksoy K
- Aktas Mk
- Aktekin H
- Al-Mousawi A
- Al-Nasser A
- Al-Nasser Z
- Al-Obaedi O
- Al-Robeye A
- Albayrak D
- Alberdi San Roman I
- Alberti Delgado P
- Alcazar Montero Ja
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- Alconchel-Gago F
- Aldrey I
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- Yıgman S
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
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- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
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- Yurekli Am
- Zaidi R
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- Zimmerman D
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- Zuhair M
- Örhalmi J
- Özkan Bb
- Šimáčková B
- Široká M
- Žebrák R
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien\u2013Dindo Grades III\u2013V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49\u20132.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46\u20130.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
- Author
- Aarts E.
- Abbas Z.
- Abburu S.
- Abd Ghaffar M.K.
- Abdelgalil R.
- Abdelhadi M.
- Abdikadir H.R.
- Abdulmajid A.
- Abdulrahman N.
- Abid A.
- Abid H.
- Abrisqueta Carrion J.
- Abuhussein N.
- Abul M.H.
- Acar S.
- Acherman Y.I.Z.
- Acquaah F.
- Acres M.
- Adams R.
- Adams R.D.
- Adebayo A.A.
- Adeleja I.
- Adiyaman C.
- Adjei H.
- Adlan A.
- Afzal Z.
- Agalar C.
- Agarwal V.
- Agrawal M.
- Ahern N.
- Ahmad A.
- Ahmad K.
- Ahmad S.
- Ahmed F.
- Ahmed H.
- Ahmed M.
- Ahmed N.
- Ahmed S.
- Ahn J.S.
- Aidoo-Micah G.E.
- Aildasani L.
- Aithie J.M.
- Akbulut F.
- Akcaoglu T.
- Akdogan A.
- Akhtar S.
- Akkaya E.
- Akkucuk S.
- Akpunarli B.
- Aksoy K.
- Aktas M.K.
- Aktekin H.
- Al-Mousawi A.
- Al-Nasser A.
- Al-Nasser Z.
- Al-Obaedi O.
- Al-Robeye A.
- Albayrak D.
- Alberdi San Roman I.
- Alberti Delgado P.
- Alcazar Montero J.A.
- Alcocer B.P.
- Alconchel-Gago F.
- Aldrey I.
- Ali A.
- Ali B.
- Ali H.
- Ali M.
- Ali S.
- Alim Y.E.
- Aliseda-Jover D.
- Alizadeh M.
- Aljbour A.
- Aljbour I.
- Allan C.
- Allen J.L.Y.
- Allot R.
- Alonso Gonçalves S.
- Alonso Hernandez N.
- Altintas O.
- Altomare D.F.
- Alvarez Reyes I.
- Amajuoyi A.
- Amarelo Garcia M.
- Ambrona-Zafra D.
- Amelung F.J.
- Amin H.
- Amin O.
- Amphlett A.H.
- Anabitarte O.
- Anakwenze V.
- Anandarajah C.
- Anania G.
- Anconelli D.
- Anderson L.
- Anderson L.B.
- Anderson R.G.J.
- Anderson S.M.
- Ang A.
- Angelov S.
- Anilkumar A.
- Anim-Addo N.
- Ankarali T.
- Ansari N.
- Antoniou I.
- Anyan-Brown J.
- Aonzo P.
- Apicella M.
- Aquilino F.
- Aray E.
- Archer C.H.
- Archer M.
- Arcudi C.
- Arenal J.J.
- Arezzo A.
- Argenti F.
- Arif T.
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- Publication venue
- Publication date
- 01/08/2018
- Field of study
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien–Dindo Grades III–V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49–2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46–0.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
The impact of stapling technique and surgeon specialism on anastomotic failure after right?sided colorectal resection: an international multicentre, prospective audit
- Author
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- Zambrano Muñoz R
- Zammit M
- Zapolskiy A
- Zawadzki M
- Zerpa Martin C
- Zimmerman D
- Zmora O
- Zmora O
- Álvarez Conde J
- Álvarez Laso C
- Örhalmi J
- Øresland T
- Švagždys S
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aim
There is little evidence to support choice of technique and configuration for stapled anastomoses after right hemicolectomy and ileocaecal resection. This study aimed to determine the relationship between stapling technique and anastomotic failure.
Method
Any unit performing gastrointestinal surgery was invited to contribute data on consecutive adult patients undergoing right hemicolectomy or ileocolic resection to this prospective, observational, international, multicentre study. Patients undergoing stapled, side?to?side ileocolic anastomoses were identified and multilevel, multivariable logistic regression analyses were performed to explore factors associated with anastomotic leak.
Results
One thousand three hundred and forty?seven patients were included from 200 centres in 32 countries. The overall anastomotic leak rate was 8.3%. Upon multivariate analysis there was no difference in leak rate with use of a cutting stapler for apical closure compared with a noncutting stapler (8.4% vs 8.0%, OR 0.91, 95% CI 0.54–1.53, P = 0.72). Oversewing of the apical staple line, whether in the cutting group (7.9% vs 9.7%, OR 0.87, 95% CI 0.52–1.46, P = 0.60) or noncutting group (8.9% vs 5.7%, OR 1.40, 95% CI 0.46–4.23, P = 0.55) also conferred no benefit in terms of reducing leak rates. Surgeons reporting to be general surgeons had a significantly higher leak rate than those reporting to be colorectal surgeons (12.1% vs 7.3%, OR 1.65, 95% CI 1.04–2.64, P = 0.04).
Conclusion
This study did not identify any difference in anastomotic leak rates according to the type of stapling device used to close the apical aspect. In addition, oversewing of the anastomotic staple lines appears to confer no benefit in terms of reducing leak rates. Although general surgeons operated on patients with more high?risk characteristics than colorectal surgeons, a higher leak rate for general surgeons which remained after risk adjustment needs further exploration
The relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit.
- Author
- Abraham Nordling M
- Abrisqueta J
- Achkasov S
- Agalianos C
- Agarwal T
- Agha A
- Aguilar Teixido F
- Aguiló Lucia J
- Ahlberg M
- Ahmed J
- Ais G
- Aiupov R
- Akhtar M
- Akmalov Y
- Akrida I
- Al Naimi N
- Al Qaddo A
- Alam N
- Alcantara Moral M
- Alcazar Montero J
- Aldrey Cao I
- Aleksic A
- Ali G
- Alias D
- Aliev I
- Allan S
- Almeida A
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- Amilka Ayala Candia B
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- Watson A
- Watson N
- Watson R
- Weaver H
- Weerts J
- Weindl I
- Weixler B
- White I
- Williams G
- Williams G
- Williams M
- Wilson J
- Winter D
- Wojciech W
- Wolthuis A
- Wrafter P
- Yamamoto T
- Yan Qi Tan J
- Yauw S
- Yeung J
- Yilmazlar T
- Yonkov A
- Yousefi P
- Yuksel O
- Zafirov G
- Zambrano Muñoz R
- Zammit M
- Zapolskiy A
- Zawadzki M
- Zerpa Martin C
- Zimmerman D
- Zmora O
- Zmora O
- Álvarez Conde J
- Álvarez Laso C
- Örhalmi J
- Øresland T
- Švagždys S
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND:
Anastomosis technique following right sided colonic resection is widely variable and may affect patient outcomes. This study aimed to assess the association between leak and anastomosis technique (stapled versus handsewn) METHODS: This was a prospective, multicentre, international audit including patients undergoing elective or emergency right hemicolectomy or ileo-caecal resection operations over a two-month period in early 2015. The primary outcome measure was the presence of anastomotic leak within 30 days of surgery, using a pre-specified definition. Mixed effects logistic regression models were used to assess the association between leak and anastomosis method, adjusting for patient, disease and operative cofactors, with centre included as a random effect variable.
RESULTS:
This study included 3208 patients, of whom 78.4% (n=2515) underwent surgery for malignancy and 11.7% (n=375) for Crohn's disease. An anastomosis was performed in 94.8% (n=3041) of patients, which was handsewn in 38.9% (n=1183) and stapled in 61.1% (n=1858) cases. Patients undergoing handsewn anastomosis were more likely to be emergency admissions (20.5% handsewn versus 12.9% stapled) and to undergo open surgery (54.7% versus 36.6%). The overall anastomotic leak rate was 8.1% (245/3041), which was similar following handsewn (7.4%) and stapled (8.5%) techniques (p=0.3). After adjustment for cofactors, the odds of a leak were higher for stapled anastomosis (adjusted odds ratio 1.43, 95% confidence interval 1.04-1.95, p=0.03).
DISCUSSION:
Despite being used in lower risk patients, stapled anastomosis was associated with an increased anastomotic leak rate in this observational study. Further research is needed to define patient groups in whom a stapled anastomosis is safe. This article is protected by copyright. All rights reserve