4,028 research outputs found
The Effects of Styles of Dress on First Impressions
Many factors influence our first impression. Previous research found that clothes may affect people’s perceptions and attitudes toward others. Even subtle changes in the style of dress would affect others’ perceptions on multiple characters such as success, trustworthiness and reliability (Howlett, Pine, & Orakcioglu, 2013). It has also been found that the amount of similarities between raters and the individuals rated were positively correlated with the rating scores of favorable characteristics (Michinov & Michinov, 2011).The current research aimed to investigate how a person’s own style of dress would influence their perception on attraction based on those individuals’ style of dress. It was predicted that individuals would perceive others with the same style of dress as more attractive than those in different style of dress.
To test this, an online survey was sent to undergraduate students in Cedarville University via a campus-wide email. Five hundred and fifty two participants were randomly shown six pictures of a male and a female model wearing one of three styles of dress, including hipster, classy, or athletic. The faces of the model were blurred. Participants were then asked to evaluate models’ characteristics on a 7 point Likert scale based on the statements, such as “This person is attractive. One is strongly disagree and seven is strongly agree. At end of the survey, the participants were also asked to report their own daily style of dress.
Factorial ANOVA Analyses were conducted to compare the differences of the rating scores on the male and female models in three different style of dress. There were significant interactions between participants’ own style of dress and the model’s dress. The preliminary results indicated that participants tended to view the models wearing the same style of dress as more attractive than those in different styles of dress.
Overall, the current study provided new evidence that a person’s own style of dress might impact their perception of others’ attraction as related to dress style. Individuals tended to view others with the same style of dress as more attractive
Fine-Needle Aspiration Cytology of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma Is Cytomorphologically Distinct From the Invasive Counterpart
Objectives: To review a series of noninvasive encapsulated follicular variant of papillary thyroid carcinomas (FVPTCs) in an attempt to further define the role of cytopathology in the diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features and invasive FVPTC.
Methods: Surgical pathology cases diagnosed as FVPTC with correlating thyroid fine-needle aspiration (FNA) were identified and divided into two FVPTC groups: noninvasive and invasive. Cytologic diagnoses were compared between them.
Results: We identified 23 cases that met the criteria for noninvasive FVPTC and 27 cases that were typical infiltrative FVPTC (n = 16) or encapsulated FVPTC with either capsular and/or lymphovascular invasion (n = 11). Of the noninvasive FVPTC cases, there were four benign lesions, 14 follicular lesions of undetermined significance (FLUS), four follicular neoplasms (FNs), one suspicious case, and no papillary thyroid carcinomas (PTCs). In the invasive FVPTC group, there were no benign cases, four FLUS, three FNs, 12 suspicious cases, and eight PTCs.
Conclusions: There is a distinction in the cytologic diagnosis between noninvasive and invasive FVPTC. The invasive subtype was diagnosed by FNA as suspicious for PTC or PTC in nearly 75% of cases, while only one (4%) case for the noninvasive subtype was diagnosed as suspicious for PTC ( P  < .05)
An empirical approach for semantic Web services discovery
Component retrieval/discovery is a well-established research direction in Software Engineering. With the surge of Service-Oriented Architecture (SOA), service discovery has become increasingly crucial. However, the public UDDI Business Registry the primary service discovery mechanism over the Internet has been shut down permanently since 2006. Moreover, keyword-based service discovery is insufficient in coping with complex discovery requirements posed by modern software developers. In this paper, we propose an empirical semantic based Web service discovery approach. It provides an automatic Web service discovery mechanism that can locate relevant Web services based on concepts rather than keywords. The major contribution of this paper is three fold. First we articulate three requirements that software developers often raise during the component/service development and discovery process. Next, we propose the application of Latent Semantic Analysis into the area of Web services discovery. To our best knowledge, little work has been done in this area which leverages concept-based Information Retrieval models in service discovery. Last, we provide a proof-of-concept system prototype that can suffice three specific requirements of semantic service discovery
Patient Trust and Resistance towards Patient Portals
Health information technologies (HITs) as facilitators of chronic disease self-management remains an ongoing topic for information system researchers. This research addresses a gap in knowledge surrounding patient trust and resistance towards using these technologies, specifically patient portals. The method used to accomplish this study is through the dispersion of a quantitative survey to participants in Ontario, Canada. This survey focused on questions related to the four variables that have been identified through the literature to be important in determining patient resistance of HITs. The results indicate the importance of patient trust in mitigating their resistance to using these technologies
Real-Time Maps of Fluid Flow Fields in Porous Biomaterials
Mechanical forces such as fluid shear have been shown to enhance cell growth
and differentiation, but knowledge of their mechanistic effect on cells is
limited because the local flow patterns and associated metrics are not
precisely known. Here we present real-time, noninvasive measures of local
hydrodynamics in 3D biomaterials based on nuclear magnetic resonance. Microflow
maps were further used to derive pressure, shear and fluid permeability fields.
Finally, remodeling of collagen gels in response to precise fluid flow
parameters was correlated with structural changes. It is anticipated that
accurate flow maps within 3D matrices will be a critical step towards
understanding cell behavior in response to controlled flow dynamics.Comment: 23 pages, 4 figure
Molecular and Histopathological Changes in Mouse Intestinal Tissue After Proton Exposure
Whole body exposure to protons in mice causes significant apoptosis in the crypts of the small intestine. Increasing numbers of crypts contained more apoptotic lesions as the dose of exposure increased. 16 genes associated with apoptotic pathways were shown to have significantly altered expression as compared to control samples for at least one of the doses of proton exposure 1 gene, Trp53inp1, was significantly up-regulated across all three doses. Those animals exposed to 0.1 Gy of proton irradiation showed greater amounts of significant alterations in gene expression as compared to 1 Gy and 2 Gy exposures. The differences in gene expression changes of low and high dose proton irradiated mice may offer insight into the molecular mechanisms of the possible high sensitivity at low proton doses. RAIDD (CRADD) may be responsible for the hypersensitivity observed in the duodenum of mice exposed to low doses of protons. Caspase-1 may also play a role in the hypersensitivity seen following proton irradiation at a dose of 0.1 Gy. FOXO3A may be involved in the down-regulation of GILZ observed at high doses of proton exposure
A Comparison of Molecular and Histopathological Changes in Mouse Intestinal Tissue Following Whole-Body Proton- or Gamma-Irradiation
There are many consequences following exposure to the space radiation environment which can adversely affect the health of a crew member. Acute radiation syndrome (ARS) involving nausea and vomiting, damage to radio-sensitive tissue such as the blood forming organs and gastrointestinal tract, and cancer are some of these negative effects. The space radiation environment is ample with protons and contains gamma rays as well. Little knowledge exists to this point, however, regarding the effects of protons on mammalian systems; conversely several studies have been performed observing the effects of gamma rays on different animal models. For the research presented here, we wish to compare our previous work looking at whole-body exposure to protons using a mouse model to our studies of mice experiencing whole-body exposure to gamma rays as part of the radio-adaptive response. Radio-adaptation is a well-documented phenomenon in which cells exposed to a priming low dose of radiation prior to a higher dose display a reduction in endpoints like chromosomal aberrations, cell death, micronucleus formation, and more when compared to their counterparts receiving high dose-irradiation only. Our group has recently completed a radio-adaptive experiment with C57BL/6 mice. For both this study and the preceding proton research, the gastrointestinal tract of each animal was dissected four hours post-irradiation and the isolated small intestinal tissue was fixed in formalin for histopathological examination or snap-frozen in liquid nitrogen for RNA isolation. Histopathologic observation of the tissue using standard H&E staining methods to screen for morphologic changes showed an increase in apoptotic lesions for even the lowest doses of 0.1 Gy of protons and 0.05 Gy of gamma rays, and the percentage of apoptotic cells increased with increasing dose. A smaller percentage of crypts showed 3 or more apoptotic lesions in animals that received 6 Gy of gamma-irradiation compared to mice receiving only 2 Gy of protons. Tissue of the gastrointestinal tract was also homogenized and RNA was isolated for cDNA synthesis and real-time PCR analysis. Inspecting apoptotic lesions of the duodenum of the small intestine as an endpoint of damage did not reveal a radio-adaptive response in C57BL/6 mice at the four hour time point. Results of gene expression changes showed consistent up or down regulation of a number of genes for all of the exposure doses that may play a role in proton-induced apoptosis. Preliminary results of gene expression alterations as a result of gamma-irradiation revealed a wealth of genes involved in oxidative stress and antioxidant defense processes being up- or down-regulated only at the highest exposure dose of 6 Gy and the combined dose of 5 cGy with 6 Gy. Those animals undergoing only 5 cGy of gamma-irradiation showed very little modification of gene expression. Taken together these results lead us to conclude that protons cause more severe morphologic damage to the duodenum of the small intestine at a dose of 2 Gy than a higher dose of 6 Gy of gamma rays to the same organ. Both protons and gamma rays lead to significant variation in gene expression at high doses in the small intestine and these changes may provide insight into the mechanism of injury seen in the gastrointestinal tract following radiation exposure. Astronauts experiencing prolonged exposure to protons in the low Earth orbit and in deep space, and experiencing acute exposure to protons from solar particle events, may face biological consequences that will impact a mission s success. We will continue this work by studying, quantifying, and comparing damage due to protons and gamma rays in the small intestine as well as other organs in a time-dependent manner
Small fibre neuropathy in sarcoidosis
Sarcoidosis is characterized by multisystem granulomatous formation particularly in the chest. In this case report, we present an uncommon case highlighting significant peripheral nerve involvement, a phenomenon that is not well recognized in sarcoidosis. The patient presented with severe incapacitating pain. Sarcoidosis as being the underlying cause was only established after extensive investigations. This case highlights the importance of recognizing small fibre peripheral polyneuropathy as a possible presentation of sarcoidosis. This could help to direct appropriate medical intervention
Illness perceptions within 6 months of cancer diagnosis are an independent prospective predictor of health-related quality of life 15 months post-diagnosis
Objective: Studies have found that illness perceptions explain significant variance in health outcomes in numerous diseases. However, most of the research is cross-sectional and non-oncological. We examined, for the first time in breast, colorectal and prostate cancer patients, if cognitive and emotional illness perceptions near diagnosis predict future multidimensional health-related quality of life (HRQoL). Methods: UK-based patients (N = 334) completed the illness perception questionnaire-revised within 6 months post-diagnosis and the quality of life in adult cancer survivors scale 15 months post-diagnosis. Sociodemographic and clinical data were obtained from medical records. Hierarchical multiple regression analyses were conducted. Results: The sociodemographic and clinical factors collectively significantly predicted 8/12 HRQoL domains, although for 5/8 accounted for <10% of the variance. For all 12 HRQoL domains, illness perceptions collectively explained significant substantial additional variance (∆R² range: 5.6–27.9%), and a single illness perception questionnaire-revised dimension was the best individual predictor of 9/12 HRQoL domains. The consequences dimension independently predicted 7/12 HRQoL domains; patients who believed their cancer would have a more serious negative impact on their life reported poorer future HRQoL. The emotional representations and identity dimensions also predicted multiple HRQoL domains. Conclusions: Future research should focus on realising the potential of illness perceptions as a modifiable target for and mediating mechanism of interventions to improve patients' HRQoL
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