339 research outputs found
Erratum: Human scFv SIgA expressed on Lactococcus lactis as a vector for the treatment of mucosal disease
NONLINEARITIES, SCALE-DEPENDENCE, AND INDIVIDUALISM OF BOREAL FOREST TREES TO CLIMATE FORCING
Changes in climate are affecting tree growth, fire regimes and the geographic ranges of species (Beck et al. 2011; Kelly et al. 2013). Increasing our understanding of how boreal tree species respond to climate warming is critical for predicting the future states of the boreal forest and assessing the global impacts of these changes. Black spruce (Picea mariana [Mill.] B.S.P.) is the most abundant tree species in the Interior Alaskan boreal forest. Although it grows in a variety of community types (Hollingsworth et al. 2006), it is the only tree species found at the coldest, wettest sites on the landscape. Despite its abundance, very little is known about the climate-growth relationships of black spruce, as the majority of dendrochronological studies in Interior Alaska involve white spruce growing at treeline.Funding was provided by a National Science Foundation grant (ARC-0902169), the Scenarios Network for Alaska and Arctic Planning, and the Alaska Climate Science Center (Cooperative Agreement Number G10AC00588 from the U.S. Geological Survey)
Molecular Epidemiology of Anthrax Cases Associated with Recreational Use of Animal Hides and Yarn in the United States
To determine potential links between the clinical isolate to animal products and their geographic origin, we genotyped (MLVA-8, MVLA-15, and canSNP analysis) 80 environmental and 12 clinical isolates and 2 clinical specimens from five cases of anthrax (California in 1976 [nâ=â1], New York in 2006 [nâ=â1], Connecticut in 2007 [nâ=â2], and New Hampshire in 2009[nâ=â1]) resulting from recreational handling of animal products. For the California case, four clinical isolates were identified as MLVA-8 genotype (GT) 76 and in the canSNP A.Br.Vollum lineage, which is consistent with the Pakistani origin of the yarn. Twenty eight of the California isolates were in the A.Br.Vollum canSNP lineage and one isolate was in the A.Br. 003/004 canSNP sub-group. All 52 isolates and both clinical specimens related to the New York and Connecticut cases were MLVA-8 GT 1. The animal products associated with the NY and CT cases were believed to originate from West Africa, but no isolates from this region are available to be genotyped for comparison. All isolates associated with the New Hampshire case were identical and had a new genotype (GT 149). Isolates from the NY, CT and NH cases diverge from the established canSNP phylogeny near the base of the A.Br.011/009. This report illustrates the power of the current genotyping methods and the dramatically different epidemiological conditions that can lead to infections (i.e., contamination by a single genotype versus widespread contamination of numerous genotypes). These cases illustrate the need to acquire and genotype global isolates so that accurate assignments can be made about isolate origins
Three Distinct Roles for Notch in Drosophila R7 Photoreceptor Specification
During specification of the R7 photoreceptor in the <I>Drosophila</I> eye, activation of Notch signaling leads to multiple responses within the cell, including antagonistic ones
The state of the Martian climate
60°N was +2.0°C, relative to the 1981â2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
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