1,259 research outputs found
Current-density functional for disordered systems
The effective action for the current and density is shown to satisfy an
evolution equation, the functional generalization of Callan-Symanzik equation.
The solution describes the dependence of the one-particle irreducible vertex
functions on the strength of the quenched disorder and the annealed Coulomb
interaction. The result is non-perturbative, no small parameter is assumed. The
a.c. conductivity is obtained by the numerical solution of the evolution
equation on finite lattices in the absence of the Coulomb interaction. The
static limit is performed and the conductivity is found to be vanishing beyond
a certain threshold of the impurity strength.Comment: final version, 28 pages, 17 figures, to appear in Phys. Rev.
Dichromatic polynomials and Potts models summed over rooted maps
We consider the sum of dichromatic polynomials over non-separable rooted
planar maps, an interesting special case of which is the enumeration of such
maps. We present some known results and derive new ones. The general problem is
equivalent to the -state Potts model randomized over such maps. Like the
regular ferromagnetic lattice models, it has a first-order transition when
is greater than a critical value , but is much larger - about 72
instead of 4.Comment: 29 pages, three figures changes in App D, introduction and
acknowledgement
Impact of tumor size and tracer uptake heterogeneity in (18)F-FDG PET and CT non-small cell lung cancer tumor delineation.: 18F-FDG PET and CT tumor delineation in NSCLC
International audienceUNLABELLED: The objectives of this study were to investigate the relationship between CT- and (18)F-FDG PET-based tumor volumes in non-small cell lung cancer (NSCLC) and the impact of tumor size and uptake heterogeneity on various approaches to delineating uptake on PET images. METHODS: Twenty-five NSCLC cancer patients with (18)F-FDG PET/CT were considered. Seventeen underwent surgical resection of their tumor, and the maximum diameter was measured. Two observers manually delineated the tumors on the CT images and the tumor uptake on the corresponding PET images, using a fixed threshold at 50% of the maximum (T(50)), an adaptive threshold methodology, and the fuzzy locally adaptive Bayesian (FLAB) algorithm. Maximum diameters of the delineated volumes were compared with the histopathology reference when available. The volumes of the tumors were compared, and correlations between the anatomic volume and PET uptake heterogeneity and the differences between delineations were investigated. RESULTS: All maximum diameters measured on PET and CT images significantly correlated with the histopathology reference (r > 0.89, P < 0.0001). Significant differences were observed among the approaches: CT delineation resulted in large overestimation (+32% ± 37%), whereas all delineations on PET images resulted in underestimation (from -15% ± 17% for T(50) to -4% ± 8% for FLAB) except manual delineation (+8% ± 17%). Overall, CT volumes were significantly larger than PET volumes (55 ± 74 cm(3) for CT vs. from 18 ± 25 to 47 ± 76 cm(3) for PET). A significant correlation was found between anatomic tumor size and heterogeneity (larger lesions were more heterogeneous). Finally, the more heterogeneous the tumor uptake, the larger was the underestimation of PET volumes by threshold-based techniques. CONCLUSION: Volumes based on CT images were larger than those based on PET images. Tumor size and tracer uptake heterogeneity have an impact on threshold-based methods, which should not be used for the delineation of cases of large heterogeneous NSCLC, as these methods tend to largely underestimate the spatial extent of the functional tumor in such cases. For an accurate delineation of PET volumes in NSCLC, advanced image segmentation algorithms able to deal with tracer uptake heterogeneity should be preferred
Spin glass transition in a magnetic field: a renormalization group study
We study the transition of short range Ising spin glasses in a magnetic
field, within a general replica symmetric field theory, which contains three
masses and eight cubic couplings, that is defined in terms of the fields
representing the replicon, anomalous and longitudinal modes. We discuss the
symmetry of the theory in the limit of replica number n to 0, and consider the
regular case where the longitudinal and anomalous masses remain degenerate.
The spin glass transitions in zero and non-zero field are analyzed in a
common framework. The mean field treatment shows the usual results, that is a
transition in zero field, where all the modes become critical, and a transition
in non-zero field, at the de Almeida-Thouless (AT) line, with only the replicon
mode critical. Renormalization group methods are used to study the critical
behavior, to order epsilon = 6-d. In the general theory we find a stable
fixed-point associated to the spin glass transition in zero field. This
fixed-point becomes unstable in the presence of a small magnetic field, and we
calculate crossover exponents, which we relate to zero-field critical
exponents. In a finite magnetic field, we find no physical stable fixed-point
to describe the AT transition, in agreement with previous results of other
authors.Comment: 36 pages with 4 tables. To be published in Phys. Rev.
Quantum trajectory approach to stochastically-induced quantum interference effects in coherently-driven two-level atoms
Stochastic perturbation of two-level atoms strongly driven by a coherent
light field is analyzed by the quantum trajectory method. A new method is
developed for calculating the resonance fluorescence spectra from numerical
simulations. It is shown that in the case of dominant incoherent perturbation,
the stochastic noise can unexpectedly create phase correlation between the
neighboring atomic dressed states. This phase correlation is responsible for
quantum interference between the related transitions resulting in anomalous
modifications of the resonance fluorescence spectra.Comment: paper accepted for publicatio
Stereoscopic Analysis of the 19 May 2007 Erupting Filament
A filament eruption, accompanied by a B9.5 flare, coronal dimming and an EUV
wave, was observed by the Solar TERrestrial Relations Observatory (STEREO) on
19 May 2007, beginning at about 13:00 UT. Here, we use observations from the
SECCHI/EUVI telescopes and other solar observations to analyze the behavior and
geometry of the filament before and during the eruption. At this time, STEREO A
and B were separated by about 8.5 degrees, sufficient to determine the
three-dimensional structure of the filament using stereoscopy. The filament
could be followed in SECCHI/EUVI 304 A stereoscopic data from about 12 hours
before to about 2 hours after the eruption, allowing us to determine the 3D
trajectory of the erupting filament. From the 3D reconstructions of the
filament and the chromospheric ribbons in the early stage of the eruption,
simultaneous heating of both the rising filamentary material and the
chromosphere directly below is observed, consistent with an eruption resulting
from magnetic reconnection below the filament. Comparisons of the filament
during eruption in 304 A and Halpha show that when it becomes emissive in He
II, it tends to disappear in Halpha, indicating that the disappearance probably
results from heating or motion, not loss, of filamentary material.Comment: Accepted for publication in Solar Physic
DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1
DNA single-strand breaks (SSBs) are the commonest DNA lesions arising spontaneously in cells, and if not repaired may block transcription or may be converted into potentially lethal/clastogenic DNA double-strand breaks (DSBs). Recently, evidence has emerged that defects in the rapid repair of SSBs preferentially impact the nervous system. In particular, spinocerebellar ataxia with axonal neuropathy (SCAN1) is a human disease that is associated with mutation of TDP1 (tyrosyl DNA phosphodiesterase 1) protein and with a defect in repairing certain types of SSBs. Although SCAN1 is a rare neurodegenerative disorder, understanding the molecular basis of this disease will lead to better understanding of neurodegenerative processes. Here we review recent progress in our understanding of TDP1, single-strand break repair (SSBR), and neurodegenerative disease
A tale of two capitalisms: preliminary spatial and historical comparisons of homicide rates in Western Europe and the USA
This article examines comparative homicide rates in the United States and Western Europe in an era of increasingly globalized neoliberal economics. The main finding of this preliminary analysis is that historical and spatial correlations between distinct forms of political economy and homicide rates are consistent enough to suggest that social democratic regimes are more successful at fostering the socio-cultural conditions necessary for reduced homicide rates. Thus Western Europe and all continents and nations should approach the importation of American neo-liberal economic policies with extreme caution. The article concludes by suggesting that the indirect but crucial causal connection between political economy and homicide rates, prematurely pushed into the background of criminological thought during the ‘cultural turn’, should be returned to the foreground
The Self Model and the Conception of Biological Identity in Immunology
The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for sixty years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal circumstances, induce an immune reaction. In this paper we show that the self/non-self model is no longer an appropriate explanation of experimental data in immunology, and that this inadequacy may be rooted in an excessively strong metaphysical conception of biological identity. We suggest that another hypothesis, one based on the notion of continuity, gives a better account of immune phenomena. Finally, we underscore the mapping between this metaphysical deflation from self to continuity in immunology and the philosophical debate between substantialism and empiricism about identity
From dynamical scaling to local scale-invariance: a tutorial
Dynamical scaling arises naturally in various many-body systems far from
equilibrium. After a short historical overview, the elements of possible
extensions of dynamical scaling to a local scale-invariance will be introduced.
Schr\"odinger-invariance, the most simple example of local scale-invariance,
will be introduced as a dynamical symmetry in the Edwards-Wilkinson
universality class of interface growth. The Lie algebra construction, its
representations and the Bargman superselection rules will be combined with
non-equilibrium Janssen-de Dominicis field-theory to produce explicit
predictions for responses and correlators, which can be compared to the results
of explicit model studies.
At the next level, the study of non-stationary states requires to go over,
from Schr\"odinger-invariance, to ageing-invariance. The ageing algebra admits
new representations, which acts as dynamical symmetries on more general
equations, and imply that each non-equilibrium scaling operator is
characterised by two distinct, independent scaling dimensions. Tests of
ageing-invariance are described, in the Glauber-Ising and spherical models of a
phase-ordering ferromagnet and the Arcetri model of interface growth.Comment: 1+ 23 pages, 2 figures, final for
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