The Shifting Boundaries of Teacher Professionalism: Education Privatization(s) in the Post-Socialist Education Space

Educators worldwide have been caught in the middle of complex globalization debates. One such debate has centered on the role of international education “experts”—usually of Western origin-in the construction and dissemination of “best practices” globally. Whether advising national governments or consulting for international development agencies (such as the World Bank, Organization for Economic Cooperation and Development or the United Nations), these “experts” have operated on the assumption that there exists a common and legitimate “blueprint” of educational policies and practices, which would lead (if implemented properly) to increased educational opportunities and improved educational quality worldwide. In the context of (neo)liberal globalization, they have been called upon to advise governments on such salient policy topics as education governance, teaching methods, curriculum reform, or (in the case of American international development assistance) anti-terrorism. More oen than not, their advice has focused on the diusion of global education policies and practices that, for many scholars in comparative education, have been central in analyses of the coercive spread of (neo)liberal education reforms such as standardization of curricula, decentralization and privatization of schools, or the introduction of national educational assessment and international testing (Dale, 2000; Apple, 2006, 2009; Arnove and Torres, 2007; Robertson, 2007; Torres, 2009; Rizvi and Lingard, 2010)

Measuring what matters? mapping higher education internationalization in the Asia–Pacific

Purpose – This paper sought to understand at one time point what was known and not known about the status and use of indicators of internationalization of higher education in Asia–Pacific. More specifically, we identified and mapped publicly available indicators of international of higher education in the region. We examined the ways by which internationalization has been measured and the indicators used, setting up discussion of what may be missing from internationalization efforts. Design/methodology/approach – The primary questions were: (1) What are the current available sources of data in the Asia–Pacific region? (2) How is internationalization measured in publicly available databases and academic materials in Asia–Pacific? To answer these questions, we carried out a structured search of academic and agency literatures. Review of these literatures led us to develop definitions and a classification system by which indicators were classified and examined. Findings – Indicators clustered almost exclusively around measures of student mobility, neglecting a wide range of other possible measures. The authors discuss the implications for internationalization of higher education in the region and draw on existing critical literature to speculate why this might be the case, and what dimensions of internationalization are likely overlooked with such a limited focus. Originality/value – Internationalization of higher education has gained considerable momentum worldwide in recent years, and higher education in the Asia–Pacific region is arguably the world’s most dynamic. Despite such dynamism, no research to our knowledge has mapped the way in which internationalization is measured by actors in the region

Transcribing Ragtime for Guitar

Classic ragtime piano solos can be made playable on guitar. The guitar, of course, is home to capabilities and limitations alien to the piano, and we start by trying to appreciate them fully. Unlike the piano, the guitar is amenable to a variety of disparate techniques, many of which can be applied to ragtime transcription. Ultimately, the author\u27s technique- essentially classical guitar- is assumed a basis for transcription, and a generalized technique for transcription, especially considerate of the ragtime style, is presented

Phylogenetic relationships of African green snakes (genera Philothamnus and Hapsidophrys) from São Tomé, Príncipe and Annobon islands based on mtDNA sequences, and comments on their colonization and taxonomy

Mitochondrial sequences (16S rRNA and cytochrome b) of the colubrine snake genera Philothamnus and Hapsidophrys were analysed. Samples were obtained from three volcanic islands in the Gulf of Guinea. The main objective was to infer phylogenetic relationships between the taxa and to trace back the colonization patterns of the group. Both insular species, Philothamnus girardi and Philothamnus thomensis, form a monophyletic unit indicating a single colonization event of one island (probably São Tomé) followed by dispersal to Annobon. Genetic divergence was found to be relatively low when compared with other Philothamnus species from the African mainland, but sufficient to consider the two taxa as distinct sister species. Here we also present evidence on the distinct phylogenetic position of Hapsidophrys sp. from the island of Príncipe, which should be considered as a distinct species, Hapsidophrys principis, a sister taxon of H. smaragdina.info:eu-repo/semantics/publishedVersio

Translating Glucose Variability Metrics into the Clinic via Continuous Glucose Monitoring: A Graphical User Interface for Diabetes Evaluation (CGM-GUIDE)

Background: Several metrics of glucose variability have been proposed to date, but an integrated approach that provides a complete and consistent assessment of glycemic variation is missing. As a consequence, and because of the tedious coding necessary during quantification, most investigators and clinicians have not yet adopted the use of multiple glucose variability metrics to evaluate glycemic variation. Methods: We compiled the most extensively used statistical techniques and glucose variability metrics, with adjustable hyper- and hypoglycemic limits and metric parameters, to create a user-friendly Continuous Glucose Monitoring Graphical User Interface for Diabetes Evaluation (CGM-GUIDE-). In addition, we introduce and demonstrate a novel transition density profile that emphasizes the dynamics of transitions between defined glucose states. Results: Our combined dashboard of numerical statistics and graphical plots support the task of providing an integrated approach to describing glycemic variability. We integrated existing metrics, such as SD, area under the curve, and mean amplitude of glycemic excursion, with novel metrics such as the slopes across critical transitions and the transition density profile to assess the severity and frequency of glucose transitions per day as they move between critical glycemic zones. Conclusions: By presenting the above-mentioned metrics and graphics in a concise aggregate format, CGM-GUIDE provides an easy to use tool to compare quantitative measures of glucose variability. This tool can be used by researchers and clinicians to develop new algorithms of insulin delivery for patients with diabetes and to better explore the link between glucose variability and chronic diabetes complications.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90437/1/dia-2E2011-2E0099.pd

Absolute dimensions of the G7+K7 eclipsing binary star IM Virginis: Discrepancies with stellar evolution models

We report extensive spectroscopic and differential photometric BVRI observations of the active, detached, 1.309-day double-lined eclipsing binary IM Vir, composed of a G7-type primary and a K7 secondary. With these observations we derive accurate absolute masses and radii of M(1) = 0.981 +/- 0.012 M(Sun), M(2) = 0.6644 +/- 0.0048 M(Sun), R(1) = 1.061 +/- 0.016 R(Sun), and R(2) = 0.681 +/- 0.013 R(Sun) for the primary and secondary, with relative errors under 2%. The effective temperatures are 5570 +/- 100 K and 4250 +/- 130 K. The significant difference in mass makes this a favorable case for comparison with stellar evolution theory. We find that both stars are larger than the models predict, by 3.7% for the primary and 7.5% for the secondary, as well as cooler than expected, by 100 K and 150 K, respectively. These discrepancies are in line with previously reported differences in low-mass stars, and are believed to be caused by chromospheric activity, which is not accounted for in current models. The effect is not confined to low-mass stars: the rapidly-rotating primary of IM Vir joins the growing list of objects of near-solar mass (but still with convective envelopes) that show similar anomalies. The comparison with the models suggests an age of 2.4 Gyr for the system, and a metallicity [Fe/H] of approximately -0.3 that is consistent with other indications, but requires confirmation.Comment: 14 pages, 13 figures. Accepted for publication in Ap

Quercetin elevates p27Kip1 and arrests both primary and HPV16 E6/E7 transformed human keratinocytes in G1

Our previous work with primary bovine fibroblasts demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 and G2/M, in correlation with p53 activation. The expression of bovine papillomavirus type 4 (BPV-4) E7 overcame this arrest and lead to the development of tumorigenic cells lines (Beniston et al., 2001). Given the possible link between papillomavirus infection, bracken fern in the diet and cancer of the upper gastrointestinal (GI) tract in humans, we investigated whether a similar situation would occur in human cells transformed by human papillomavirus type 16 (HPV-16) oncoproteins. Quercetin arrested primary human foreskin keratinocytes in G1. Arrest was linked to an elevation of the cyclin-dependent kinase inhibitor (cdki) p27Kip1. Expression of the HPV16 E6 and E7 oncoproteins in transformed cells failed to abrogate cell cycle arrest. G1 arrest in the transformed cells was also linked to an increase of p27Kip1 with a concomitant reduction of cyclin E-associated kinase activity. This elevation of p27Kip1 was due not only to increased protein half-life, but also to increased mRNA transcription

Crop wild relatives in the South African development community

The countries of the South African Development Community (SADC) are facing unprecedented challenges related to food security, climate change and poverty reduction. The conservation and sustainable use of crop wild relatives (CWR), which is worth an estimated US$120 billion globally, should be an urgent priority for the region. This policy brief outlines the current status of the SADC’s CWR and provides an outline for policymakers to form a regional network to better protect CWR to improve food security, livelihoods, and the conservation of biodiversity

Ectopic lipid storage in non-alcoholic fatty liver disease is not mediated by impaired mitochondrial oxidative capacity in skeletal muscle

Background and Aims. Simple clinical algorithms including the Fatty Liver Index (FLI) and Lipid Accumulation Product (LAP) have been developed as a surrogate marker for Non-Alcoholic Fatty Liver Disease (NAFLD). These algorithms have been constructed using ultrasonography, a semi-quantitative method. This study aimed to validate FLI and LAP as measures of hepatic steatosis, as measured quantitatively by proton magnetic resonance spectroscopy (1H-MRS). Methods. Data were collected from 168 patients with NAFLD and 168 controls who had undergone clinical, biochemical and anthropometric assessment in the course of research studies. Values of FLI and LAP were determined, and assessed both as predictors of the presence of hepatic steatosis (liver fat >5.5 %) and of actual liver fat content, as measured by 1H MRS. The discriminative ability of FLI and LAP was estimated using the area under the Receiver Operator Characteristic curve (AUROC). Since FLI can also be interpreted as a predictive probability of hepatic steatosis, we assessed how well calibrated it was in our cohort. Linear regression with prediction intervals was used to assess the ability of FLI and LAP to predict liver fat content. Results. FLI and LAP discriminated between patients with and without hepatic steatosis with an AUROC of 0.79 (IQR= 0.74, 0.84) and 0.78 (IQR= 0.72, 0.83), although quantitative prediction of liver fat content was unsuccessful. Additionally, the algorithms accurately matched the observed percentages of patients with hepatic steatosis in our cohort. Conclusions. FLI and LAP may be used clinically, and for metabolic and epidemiological research, to identify patients with hepatic steatosis, but not as surrogates for liver fat content

Cooperative regulation of Cav1.2 channels by intracellular Mg2+, the proximal C-terminal EF-hand, and the distal C-terminal domain

L-type Ca2+ currents conducted by Cav1.2 channels initiate excitation–contraction coupling in cardiac myocytes. Intracellular Mg2+ (Mgi) inhibits the ionic current of Cav1.2 channels. Because Mgi is altered in ischemia and heart failure, its regulation of Cav1.2 channels is important in understanding cardiac pathophysiology. Here, we studied the effects of Mgi on voltage-dependent inactivation (VDI) of Cav1.2 channels using Na+ as permeant ion to eliminate the effects of permeant divalent cations that engage the Ca2+-dependent inactivation process. We confirmed that increased Mgi reduces peak ionic currents and increases VDI of Cav1.2 channels in ventricular myocytes and in transfected cells when measured with Na+ as permeant ion. The increased rate and extent of VDI caused by increased Mgi were substantially reduced by mutations of a cation-binding residue in the proximal C-terminal EF-hand, consistent with the conclusion that both reduction of peak currents and enhancement of VDI result from the binding of Mgi to the EF-hand (KD ≈ 0.9 mM) near the resting level of Mgi in ventricular myocytes. VDI was more rapid for L-type Ca2+ currents in ventricular myocytes than for Cav1.2 channels in transfected cells. Coexpression of Cavβ2b subunits and formation of an autoinhibitory complex of truncated Cav1.2 channels with noncovalently bound distal C-terminal domain (DCT) both increased VDI in transfected cells, indicating that the subunit structure of the Cav1.2 channel greatly influences its VDI. The effects of noncovalently bound DCT on peak current amplitude and VDI required Mgi binding to the proximal C-terminal EF-hand and were prevented by mutations of a key divalent cation-binding amino acid residue. Our results demonstrate cooperative regulation of peak current amplitude and VDI of Cav1.2 channels by Mgi, the proximal C-terminal EF-hand, and the DCT, and suggest that conformational changes that regulate VDI are propagated from the DCT through the proximal C-terminal EF-hand to the channel-gating mechanism