Sociodemographic Predictors of Rural Poverty: A Regional Analysis

The focus of the present study is to determine the extent to which the socio-demographic variables of education, occupation, number of children, race, sex, age, and willingness to travel for employment and predictors of a rural family\u27s level of poverty. Discriminant analysis is employed to assess the accuracy of these variables in - discriminating between poor and nonpoor families randomly selected from thirty low income, rural counties in ten contiguous southeastern states. The results are supportive of previous studies as these variables are found to be statistically significant discriminants between the poor and the nonpoor. The profile of a rural poor head of household is a poorly educated, semi-skilled, female, black, farm resident who tends to be old, have a large number of children, and be less willing to travel for employment outside of one\u27s immediate area

Male frequent attenders of general practice and their help seeking preferences

Background: Low rates of health service usage by men are commonly linked to masculine values and traditional male gender roles. However, not all men conform to these stereotypical notions of masculinity, with some men choosing to attend health services on a frequent basis, for a variety of different reasons. This study draws upon the accounts of male frequent attenders of the General Practitioner's (GP) surgery, examining their help-seeking preferences and their reasons for choosing services within general practice over other sources of support. Methods: The study extends thematic analysis of interview data from the Self Care in Primary Care study (SCinPC), a large scale multi-method evaluation study of a self care programme delivered to frequent attenders of general practice. Data were collected from 34 semi-structured interviews conducted with men prior to their exposure to the intervention. Results: The ages of interviewed men ranged from 16 to 72 years, and 91% of the sample (n= 31) stated that they had a current health condition. The thematic analysis exposed diverse perspectives within male help-seeking preferences and the decision-making behind men's choice of services. The study also draws attention to the large variation in men's knowledge of available health services, particularly alternatives to general practice. Furthermore, the data revealed some men's lack of confidence in existing alternatives to general practice. Conclusions: The study highlights the complex nature of male help-seeking preferences, and provides evidence that there should be no 'one size fits all' approach to male service provision. It also provides impetus for conducting further studies into this under researched area of interest. © 2011 WPMH GmbH

Temperature gradients in XMM-Newton observed REFLEX-DXL galaxy clusters at z~0.3

We present XMM-Newton results on the temperature profiles of a volume-limited sample of galaxy clusters at redshifts z~0.3, selected from the REFLEX survey (REFLEX-DXL sample). In the spectral analysis, where only the energies above 1 keV were considered, we obtained consistent results on the temperature derived from the EPN, EMOS1 and EMOS2 data. Useful temperature measurements could be performed out to radii with overdensity 500 (r500) for all nine clusters. We discovered a diversity in the temperature gradients at the outer cluster radii with examples of both flat and strongly decreasing profiles. Using the total mass and the gas mass profiles for the cluster RXCJ0307.0-2840 we demonstrate that the errors on the mass estimates for the REFLEX-DXL clusters are within 25% up to r500.Comment: Revised version accepted for publication in A&A, 18 page

A Cosmology of the Brane World

We develop a possible cosmology for a Universe with n additional spatial dimensions of variable scale, and an associated scalar field, the radion, which is distinct from the field responsible for inflation, the inflaton. Based on a particular ansatz for the effective potential for the inflaton and radion (which may emerge in string theory), we show that the early expansion of the Universe may proceed in three stages. First, the radion becomes trapped at a value much smaller than the size of the extra dimensions today. Second, the Universe expands exponentially, but with a Planck mass smaller than its present value. Because the Planck mass during inflation is small, density fluctuations in agreement with observations can arise naturally. Third, when inflation ends, the Universe reheats, and the radion becomes free to expand once more. During the third phase the Universe is ``radiation-dominated'' and tends toward a fixed-point evolutionary model in which the radion grows but the temperature remains unchanged. Ultimately, the radion becomes trapped once again at its present value, and a short period of exponential expansion, which we identify with the electroweak phase transition, ensues. Once this epoch is over, the Universe reheats to a temperature of order the electroweak scale, and the mature Universe evolves as in standard cosmological models. We show that the present day energy density in radions can be smaller than the closure density if the second inflationary epoch lasts about 8 e-foldings or more; the present-day radion mass turns out to be small (less than or of the order of an eV, depending on parameters). We argue that although our model envisages considerable time evolution in the Planck mass, substantial spatial fluctuations in Newton's constant are not produced.Comment: 38 pages, 2 figures, submitted to Phys Rev D. Typos corrected, references adde

A participatory physical and psychosocial intervention for balancing the demands and resources among industrial workers (PIPPI): study protocol of a cluster-randomized controlled trial

Background: Need for recovery and work ability are strongly associated with high employee turnover, well-being and sickness absence. However, scientific knowledge on effective interventions to improve work ability and decrease need for recovery is scarce. Thus, the present study aims to describe the background, design and protocol of a cluster randomized controlled trial evaluating the effectiveness of an intervention to reduce need for recovery and improve work ability among industrial workers. Methods/Design: A two-year cluster randomized controlled design will be utilized, in which controls will also receive the intervention in year two. More than 400 workers from three companies in Denmark will be aimed to be cluster randomized into intervention and control groups with at least 200 workers (at least 9 work teams) in each group. An organizational resources audit and subsequent action planning workshop will be carried out to map the existing resources and act upon initiatives not functioning as intended. Workshops will be conducted to train leaders and health and safety representatives in supporting and facilitating the intervention activities. Group and individual level participatory visual mapping sessions will be carried out allowing team members to discuss current physical and psychosocial work demands and resources, and develop action plans to minimize strain and if possible, optimize the resources. At all levels, the intervention will be integrated into the existing organization of work schedules. An extensive process and effect evaluation on need for recovery and work ability will be carried out via questionnaires, observations, interviews and organizational data assessed at several time points throughout the intervention period. Discussion: This study primarily aims to develop, implement and evaluate an intervention based on the abovementioned features which may improve the work environment, available resources and health of industrial workers, and hence their need for recovery and work ability

Increased Local Retention of Reef Coral Larvae as a Result of Ocean Warming

Climate change will alter many aspects of the ecology of organisms, including dispersal patterns and population connectivity. Understanding these changes is essential to predict future species distributions, estimate potential for adaptation, and design effective networks of protected areas. In marine environments, dispersal is often accomplished by larvae. At higher temperatures, larvae develop faster, but suffer higher mortality, making the effect of temperature on dispersal difficult to predict. Here, we experimentally calibrate the effect of temperature on larval survival and settlement in a dynamic model of coral dispersal. Our findings imply that most reefs globally will experience several-fold increases in local retention of larvae due to ocean warming. This increase will be particularly pronounced for reefs with mean water residence times comparable to the time required for species to become competent to settle. Higher local retention rates strengthen the link between abundance and recruitment at the reef scale, suggesting that populations will be more responsive to local conservation actions. Higher rates of local retention and mortality will weaken connectivity between populations, and thus potentially retard recovery following severe disturbances that substantially deplete local populations. Conversely, on isolated reefs that are dependent on replenishment from local broodstock, increases in local retention may hasten recovery

Microwave background anisotropies in quasiopen inflation

Quasiopenness seems to be generic to multi-field models of single-bubble open inflation. Instead of producing infinite open universes, these models actually produce an ensemble of very large but finite inflating islands. In this paper we study the possible constraints from CMB anisotropies on existing models of open inflation. The effect of supercurvature anisotropies combined with the quasiopenness of the inflating regions make some models incompatible with observations, and severely reduces the parameter space of others. Supernatural open inflation and the uncoupled two-field model seem to be ruled out due to these constraints for values of $\Omega_0\lesssim0.98$. Others, such as the open hybrid inflation model with suitable parameters for the slow roll potential can be made compatible with observations.Comment: 19 pages, ReVTeX, 10 figures inserted with eps

DNA cruciform arms nucleate through a correlated but non-synchronous cooperative mechanism

Inverted repeat (IR) sequences in DNA can form non-canonical cruciform structures to relieve torsional stress. We use Monte Carlo simulations of a recently developed coarse-grained model of DNA to demonstrate that the nucleation of a cruciform can proceed through a cooperative mechanism. Firstly, a twist-induced denaturation bubble must diffuse so that its midpoint is near the centre of symmetry of the IR sequence. Secondly, bubble fluctuations must be large enough to allow one of the arms to form a small number of hairpin bonds. Once the first arm is partially formed, the second arm can rapidly grow to a similar size. Because bubbles can twist back on themselves, they need considerably fewer bases to resolve torsional stress than the final cruciform state does. The initially stabilised cruciform therefore continues to grow, which typically proceeds synchronously, reminiscent of the S-type mechanism of cruciform formation. By using umbrella sampling techniques we calculate, for different temperatures and superhelical densities, the free energy as a function of the number of bonds in each cruciform along the correlated but non-synchronous nucleation pathways we observed in direct simulations.Comment: 12 pages main paper + 11 pages supplementary dat

The endocannabinoid anandamide causes endothelium-dependent vasorelaxation in human mesenteric arteries

The endocannabinoid anandamide (AEA) causes vasorelaxation in animal studies. Although circulating AEA levels are increased in many pathologies, little is known about its vascular effects in humans. The aim of this work was to characterise the effects of AEA in human arteries. Ethical approval was granted to obtain mesenteric arteries from patients (n = 31) undergoing bowel resection. Wire myography was used to probe the effects and mechanisms of action of AEA. RT‐PCR was used to confirm the presence of receptor mRNA in human aortic endothelial cells (HAECs) and intracellular signalling proteins were measured using multiplex technology. AEA caused vasorelaxation of precontracted human mesenteric arteries with an Rmax of ∼30%. A synthetic CB1 agonist (CP55940) caused greater vasorelaxation (Rmax ∼60%) while a CB2 receptor agonist (HU308) had no effect on vascular tone. AEA-induced vasorelaxation was inhibited by removing the endothelium, inhibition of nitric oxide (NO) synthase, antagonising the CB1 receptor and antagonising the proposed novel endothelial cannabinoid receptor (CBe). AEA‐induced vasorelaxation was not affected by CB2 antagonism, by depleting sensory neurotransmitters, or inhibiting cyclooxygenase activity. RT‐PCR showed CB1 but not CB2 receptors were present in HAECs, and AEA and CP55940 had similar profiles in HAECs (increased phosphorylation of JNK, NFκB, ERK, Akt, p70s6K, STAT3 and STAT5). Post hoc analysis of the data set showed that overweight patients and those taking paracetamol had reduced vasorelaxant responses to AEA. These data show that AEA causes moderate endothelium-dependent, NO-dependent vasorelaxation in human mesenteric arteries via activation of CB1 receptors