1,329 research outputs found
Cultural political economy and urban heritage tourism
The paper explains a cultural political economy âframingâ for interpreting heritage tourism in urban contexts. Key ideas behind this research perspective are explained and illustrated through discussion of past research studies of urban heritage tourism. It is underpinned by a relational view of the inter-connectedness of societal relations, and an emphasis on taking seriously both the cultural/semiotic and the economic/political in the co-constitution of urban heritage tourismâs social practices and features. A case study of heritage tourism in Nanjing, China considers cultural political economyâs relevance and value, including the distinctive research questions it raises. It reveals, for example, how economic relations in the built environment were related to tourist meaning-making and identities in the cultural/semiotic sphere
Investigating experiences of the family connections programme for supporters of individuals with a diagnosis of borderline personality disorder
We interviewed relatives and carers following their participation in a novel Family Connection (FC) programme, designed for supporters of individuals with a diagnosis of Borderline Personality Disorder. A mixed methods approach was utilised to quantitatively measure depression, âburdenâ, grief and mastery, pre and post-group, whilst qualitative analysis identified four themes: âPositive Experienceâ, âNot Aloneâ, âManagement of Emotions and Behavioursâ and âRecommendationsâ. Quantitative measures suggest that FC could be helpful in alleviating depression and âburdenâ and increasing mastery, although it could increase the experience of grief. Implications for future research and the possible impact of FC amongst this group are discussed
Early Life Socioeconomic Circumstance and Late Life Brain Hyperintensities : A Population Based Cohort Study
Funding: Image acquisition and image analysis for this study was funded by the Alzheimer's Research Trust (now Alzheimer's Research UK). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments The authors would like to thank the participants of the Aberdeen 1936 Birth Cohort (ABC36), without whom this research would not have been possible.Peer reviewedPublisher PD
Standard Model Higgs boson production in association with a top anti-top pair at NLO with parton showering
We present predictions for the production cross section of a Standard Model
Higgs boson in association with a top-antitop pair at next-to-leading order
accuracy using matrix elements obtained from the HELAC-Oneloop package. The NLO
prediction was interfaced to the PYTHIA and HERWIG shower Monte Carlo programs
with the help of POWHEG-Box, allowing for decays of massive particles,
showering and hadronization, thus leading to final results at the hadron level.Comment: 14 pages, 9 figure
Challenges of Early Years leadership preparation: a comparison between early and experienced Early Years practitioners in England
Leadership has been under-researched in the Early Years (EY) sector of primary schools in England, especially in leading change for professional development. The aim of this paper is to theorise what the leadership culture for EY practitioners looks like, and how Initial Teacher Training providers and schools are preparing practitioners for leadership. Using case studies of EY practitioners in different stages of their career in primary schools, we offer an insight into their preparedness for leadership in EY, the implication being that leadership training requires an understanding and embedding of the EY culture and context. Interviews with both sample groups allowed for deeper insight into the lived world. Interviews were also conducted with the head teachers to gain an overview of the leadership preparation they provided. The main findings suggest that newer EY practitioners are better prepared for leadership from their university training in comparison to more experienced EY practitioners
Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity
Objective
Individuals carrying rare, but biologically informative genetic variants provide a unique opportunity to model major mental illness and inform understanding of disease mechanisms. The rarity of such variations means that their study involves small group numbers, however they are amongst the strongest known genetic risk factors for major mental illness and are likely to have large neural effects. DISC1 (Disrupted in Schizophrenia 1) is a gene containing one such risk variant, identified in a single Scottish family through its disruption by a balanced translocation of chromosomes 1 and 11; t(1;11) (q42.1;q14.3).
Method
Within the original pedigree, we examined the effects of the t(1;11) translocation on white matter integrity, measured by fractional anisotropy (FA). This included family members with (n = 7) and without (n = 13) the translocation, along with a clinical control sample of patients with psychosis (n = 34), and a group of healthy controls (n = 33).
Results
We report decreased white matter integrity in five clusters in the genu of the corpus callosum, the right inferior fronto-occipital fasciculus, acoustic radiation and fornix. Analysis of the mixed psychosis group also demonstrated decreased white matter integrity in the above regions. FA values within the corpus callosum correlated significantly with positive psychotic symptom severity.
Conclusions
We demonstrate that the t(1;11) translocation is associated with reduced white matter integrity in frontal commissural and association fibre tracts. These findings overlap with those shown in affected patients with psychosis and in DISC1 animal models and highlight the value of rare but biologically informative mutations in modeling psychosis
Establishing Lagrangian connections between observations within air masses crossing the Atlantic during the International Consortium for Atmospheric Research on Transport and Transformation experiment
The ITCT-Lagrangian-2K4 (Intercontinental Transport and Chemical Transformation) experiment was conceived with an aim to quantify the effects of photochemistry and mixing on the transformation of air masses in the free troposphere away from emissions. To this end, attempts were made to intercept and sample air masses several times during their journey across the North Atlantic using four aircraft based in New Hampshire (USA), Faial (Azores) and Creil (France). This article begins by describing forecasts from two Lagrangian models that were used to direct the aircraft into target air masses. A novel technique then identifies Lagrangian matches between flight segments. Two independent searches are conducted: for Lagrangian model matches and for pairs of whole air samples with matching hydrocarbon fingerprints. The information is filtered further by searching for matching hydrocarbon samples that are linked by matching trajectories. The quality of these "coincident matches'' is assessed using temperature, humidity and tracer observations. The technique pulls out five clear Lagrangian cases covering a variety of situations and these are examined in detail. The matching trajectories and hydrocarbon fingerprints are shown, and the downwind minus upwind differences in tracers are discussed
Unique, nonâEarthlike, meteoritic ion behavior in upper atmosphere of Mars
Interplanetary dust particles have long been expected to produce permanent ionospheric metal ion layers at Mars, as on Earth, but the two environments are so different that uncertainty existed as to whether terrestrial-established understanding would apply to Mars. The Mars Atmosphere and Volatile EvolutioN (MAVEN) mission made the first in situ detection of the continuous presence of Na+, Mg+, and Fe+ at Mars and indeed revealed non-Earthlike features/processes. There is no separation of the light Mg+ and the heavy Fe+ with increasing altitude as expected for gravity control. The metal ions are well-mixed with the neutral atmosphere at altitudes where no mixing process is expected. Isolated metal ion layers mimicking Earth's sporadic E layers occur despite the lack of a strong magnetic field as required at Earth. Further, the metal ion distributions are coherent enough to always show atmospheric gravity wave signatures. All features and processes are unique to Mars
Mechanical characterization of individual NiâAu coated microsize polymer particles
This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in (DOU, G., WHALLEY, D.C. and LIU, C., 2008. Mechanical characterization of individual Ni/Au coated microsize polymer particles. Applied Physics Letters, 92(10), 104108 (8 Pages)) and may be found at http://link.aip.org/link/?APPLAB/92/104108/1We report on a mechanical characterization technique for individual Ni/Au coated microsize
polymer particles. This technique allows a clearer understanding of the effects of load force and rate
on the particle deformation. This has been achieved through measurements of the deformation
against force using a specially configured nanoindenter machine, where the âindenters,â instead of
being pointed, had a flat tip of 20 m in diameter. The results show that the particle deformation
process is nonlinear and that the force/deformation at which particle crushing occurs is affected by
the load rate. The technique could be used to design/manufacture more effective conductive
particles
- âŠ