307 research outputs found

    MATH 152.05: Calculus I

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    AMBIENT AUDIO AUTO-SUGGEST

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    A computing device can analyze ambient audio, recognize entities referenced in the ambient audio, and provide actionable notifications of the entities on a display of the computing device. As an example, a computing device may determine that audio in the background has referenced a famous person and can generate a notification that names the famous person and lists the reason that they were famous (e.g., “Basketball Player”). User selection of the notification may cause the computing device to present a user interface that shows additional information on the person and/or selectable buttons for performing actions related to the individual. These actions can include performing a search engine search using the entity name as the query, creating a note that stores the entity name, and in those circumstances when the entity is a product, navigating to a web store to purchase the product

    Contribution of the Rv1985c transcriptional regulator to Mycobacterium tuberculosis intracellular adaptation.

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    Mycobacterium tuberculosis causes the often-fatal infectious disease Tuberculosis, and infects approximately one third of the world\u27s population. Gaining a better understanding of how these bacteria regulate gene expression for intracellular survival will likely aid in developing ways to reduce disease. Studies of bacterial RNA expression in experimentally infected primary human macrophages indicated open reading frame Rv1985c, encoding a putative transcriptional regulator, may contribute to intracellular survival. Comparison of a strain constitutively expressing Rv1985c and the isogenic wildtype parent by array hybridization identified genes potentially regulated by Rv1985c. These included a group encoding factors likely relevant to cell wall remodeling, particularly modification of mycolic acids. Interestingly, of the 22 upregulated genes identified by significance analysis of microarray, S.A.M., among the highest expressed were some of those previously described as part of the DosR/DevR dormancy regulon. We verified that Rv1985c mRNA levels rose dramatically in the first 24 hours following phagocytosis, and confirmed a lack of increased dosR/devR transcription in the constitutively expressing Rv1985c strain. Finally we showed that a Rv1985c knock out mutant while able to grow normally in laboratory broth had reduced ability to colonize cultured human macrophages, and showed reduced cytopathic effects. Restoring Rv1985c reversed this attenuation of the mutant

    Fall Faculty Conference: The Future of the University

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    This was the first fall of President Robert Eckley\u27s time in office. The first part of the recording is an open Q&A session, followed by division-based reports. There are frequent references to a recent North Central reaccreditation visit in this meeting. In a memo distributed a day later President Eckley notes that the North Central visit and the recent changes in the general education requirements indicate the importance of a re-assessment of our departmental-divisional-university structural relationships. His proposal formed a structure with three colleges: Liberal Arts, Fine Arts and Applied Arts. Speakers include President Robert Eckley; Robert Harrington, Business & Economics; Justus Pearson, Humanities; Wayne Wantland, Natural Sciences; Emily Dale, Social Sciences; John Ficca, Art & Drama; Richard Hishman, Music; and Mary Shanks, Nursing

    Development of a Psychologically Enhanced Interactive Online Intervention for Hazardous Drinking

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    Aims: The content of novel interventions is often not well specified. We provide a detailed account of the rationale for and redevelopment of an Internet resource for hazardous drinkers—Down Your Drink (DYD) (www.downyourdrink.org.uk). Development Work: An iterative process blended literature reviews of Internet interventions for health conditions and brief treatments for alcohol problems, feedback from users of the original site and from users panels, and completion of a series of developmental tasks. Intervention: The detailed structure and content of the new version of the website is presented. This permits an appreciation of the intended interaction between the user and the intervention, and emphasizes both the freedom of choice available to the user to access diverse material for personal benefit and the value of a clear organizational structure. Conclusions: Presentation of detailed information on the theoretical underpinning, content and structure of an intervention makes it easier to interpret the results of any evaluation and is likely to be of use to those developing other online interventions for alcohol or other health behaviours
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