17,588 research outputs found

    Women-Loving-Women Portrayals in Fiction, a Critical Literature Review

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    Indiana University-Purdue University Indianapolis (IUPUI)This critical literature review explores the ways in which scholars have discussed depictions of fictional women-loving women (WLW) in film and on television in the past five years. This study is guided by both sexual script theory and the intersectional perspective. Prior studies of WLW in fiction have largely focused on the areas of homonormativity, race, bisexual-erasure, WLW stereotypes, gender dynamics, WLW communities, and post-modern representation. Earlier research has focused on those areas to the exclusion of giving more attention to exploring the use of queerbaiting in modern storytelling. Future research should include analyses of more recently featured fictional WLW characters and WLW relationships in film and on television in addition to more research on queerbaiting overall

    Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress.

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    Mitochondrial dysfunction has been implicated in human diseases, including cancer, and proposed to accelerate aging. The Drosophila Cyclin-dependent protein kinase complex cyclin D/cyclin-dependent kinase 4 (CycD/Cdk4) promotes cellular growth by stimulating mitochondrial biogenesis. Here, we examine the neurodegenerative and aging consequences of altering CycD/Cdk4 function in Drosophila. We show that pan-neuronal loss or gain of CycD/Cdk4 increases mitochondrial superoxide, oxidative stress markers, and neurodegeneration and decreases lifespan. We find that RNAi-mediated depletion of the mitochondrial transcription factor, Tfam, can abrogate CycD/Cdk4's detrimental effects on both lifespan and neurodegeneration. This indicates that CycD/Cdk4's pathological consequences are mediated through altered mitochondrial function and a concomitant increase in reactive oxygen species. In support of this, we demonstrate that CycD/Cdk4 activity levels in the brain affect the expression of a set of 'oxidative stress' genes. Our results indicate that the precise regulation of neuronal CycD/Cdk4 activity is important to limit mitochondrial reactive oxygen species production and prevent neurodegeneration

    Narrative coherence in multiple forensic interviews with child witnesses alleging physical and sexual abuse

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    This study investigated the narrative coherence of children's accounts elicited in multiple forensic interviews. Transcriptions of 56 police interviews with 28 children aged 3–14 years alleging physical and sexual abuse were coded for markers of completeness, consistency and connectedness. We found that multiple interviews increased the completeness of children's testimony, containing on average almost twice as much new information as single interviews, including crucial location, time and abuse‐related details. When both contradictions within the same interview and across interviews were considered, contradictions were not more frequent in multiple interviews. The frequency of linguistic markers of connectedness remained stable across interviews. Multiple interviews increase the narrative coherence of children's testimony through increasing their completeness without necessarily introducing contradictions or decreasing causal‐temporal connections between details. However, as ‘ground truth’ is not known in field studies, further investigation of the relationship between the narrative coherence and accuracy of testimonies is required

    Examining the Role of Environment in a Comprehensive Sample of Compact Groups

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    (Abridged) Compact groups, with their high number densities, small velocity dispersions, and an interstellar medium that has not been fully processed, provide a local analog to conditions of galaxy interactions in the earlier universe. The frequent and prolonged gravitational encounters that occur in compact groups affect the evolution of the constituent galaxies in a myriad of ways, for example gas processing and star formation. Recently, a statistically significant "gap" has been discovered mid-infrared IRAC colorspace of compact group galaxies. This gap is not seen in field samples and is a new example of how the compact group environment may affect the evolution of member galaxies. In order to investigate the origin and nature of this gap, we have compiled a sample of 49 compact groups. We find that a statistically significant deficit of galaxies in this gap region of IRAC colorspace is persistant in this sample, lending support to the hypothesis that the compact group environment inhibits moderate SSFRs. We note a curvature in the colorspace distribution, which is fully consistent with increasing dust temperature as the activity in a galaxy increases. This full sample of 49 compact groups allows us to subdivide the data according to physical properties of the groups. An analysis of these subsamples indicates that neither projected physical diameter nor density show a trend in colorspace within the values represented by this sample. We hypothesize that the apparent lack of a trend is due to the relatively small range of properties in this sample. Thus, the relative influence of stochastic effects becomes dominant. We analyze spectral energy distributions of member galaxies as a function of their location in colorspace and find that galaxies in different regions of MIR colorspace contain dust with varying temperatures and/or PAH emission.Comment: 24 pages, 13 figures. Accepted for publication in The Astronomical Journa

    A weakly correlated Fermi liquid state with a small Fermi surface in lightly doped Sr3_3Ir2_2O7_7

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    We characterize the electron doping evolution of (Sr1x_{1-x}Lax_x)3_3Ir2_2O7_7 by means of angle-resolved photoemission. Concomitant with the metal insulator transition around x0.05x\approx0.05 we find the emergence of coherent quasiparticle states forming a closed small Fermi surface of volume 3x/23x/2, where xx is the independently measured La concentration. The quasiparticle weight ZZ remains large along the entire Fermi surface, consistent with the moderate renormalization of the low-energy dispersion. This indicates a conventional, weakly correlated Fermi liquid state with a momentum independent residue Z0.5Z\approx0.5 in lightly doped Sr3_3Ir2_2O$_7&.Comment: 5 pages, 4 figure

    Revealing natural relationships among arbuscular mycorrhizal fungi: culture line BEG47 represents Diversispora epigaea, not Glomus versiforme

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    Background: Understanding the mechanisms underlying biological phenomena, such as evolutionarily conservative trait inheritance, is predicated on knowledge of the natural relationships among organisms. However, despite their enormous ecological significance, many of the ubiquitous soil inhabiting and plant symbiotic arbuscular mycorrhizal fungi (AMF, phylum Glomeromycota) are incorrectly classified. Methodology/Principal Findings: Here, we focused on a frequently used model AMF registered as culture BEG47. This fungus is a descendent of the ex-type culture-lineage of Glomus epigaeum, which in 1983 was synonymised with Glomus versiforme. It has since then been used as ‘G. versiforme BEG47’. We show by morphological comparisons, based on type material, collected 1860–61, of G. versiforme and on type material and living ex-type cultures of G. epigaeum, that these two AMF species cannot be conspecific, and by molecular phylogenetics that BEG47 is a member of the genus Diversispora. Conclusions: This study highlights that experimental works published during the last >25 years on an AMF named ‘G. versiforme’ or ‘BEG47’ refer to D. epigaea, a species that is actually evolutionarily separated by hundreds of millions of years from all members of the genera in the Glomerales and thus from most other commonly used AMF ‘laboratory strains’. Detailed redescriptions substantiate the renaming of G. epigaeum (BEG47) as D. epigaea, positioning it systematically in the order Diversisporales, thus enabling an evolutionary understanding of genetical, physiological, and ecological traits, relative to those of other AMF. Diversispora epigaea is widely cultured as a laboratory strain of AMF, whereas G. versiforme appears not to have been cultured nor found in the field since its original description

    Myosin V passing over Arp2/3 junctions: branching ratio calculated from the elastic lever arm model

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    Myosin V is a two-headed processive motor protein that walks in a hand-over-hand fashion along actin filaments. When it encounters a filament branch, formed by the Arp2/3 complex, it can either stay on the straight mother filament, or switch to the daughter filament. We study both probabilities using the elastic lever arm model for myosin V. We calculate the shapes and bending energies of all relevant configurations in which the trail head is bound to the actin filament before Arp2/3 and the lead head is bound either to the mother or to the daughter filament. Based on the assumption that the probability for a head to bind to a certain actin subunit is proportional to the Boltzmann factor obtained from the elastic energy, we calculate the mother/daughter filament branching ratio. Our model predicts a value of 27% for the daughter and 73% for the mother filament. This result is in good agreement with recent experimental data.Comment: 9 pages, 7 figures, to appear in Biophysical Journa

    Quasiparticle dynamics and spin-orbital texture of the SrTiO3 two-dimensional electron gas

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    Two-dimensional electron gases (2DEGs) in SrTiO3_3 have become model systems for engineering emergent behaviour in complex transition metal oxides. Understanding the collective interactions that enable this, however, has thus far proved elusive. Here we demonstrate that angle-resolved photoemission can directly image the quasiparticle dynamics of the dd-electron subband ladder of this complex-oxide 2DEG. Combined with realistic tight-binding supercell calculations, we uncover how quantum confinement and inversion symmetry breaking collectively tune the delicate interplay of charge, spin, orbital, and lattice degrees of freedom in this system. We reveal how they lead to pronounced orbital ordering, mediate an orbitally-enhanced Rashba splitting with complex subband-dependent spin-orbital textures and markedly change the character of electron-phonon coupling, co-operatively shaping the low-energy electronic structure of the 2DEG. Our results allow for a unified understanding of spectroscopic and transport measurements across different classes of SrTiO3_3-based 2DEGs, and yield new microscopic insights on their functional properties.Comment: 10 pages including supplementary information, 4+4 figure

    The Shifting Origins of International Law

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    Both state-centrism and Euro-centrism are under challenge in international law today and this double challenge, this work argues, is being fruitfully mirrored back into the study of the history of international law. It examines, in the first section, the effects of the rise of positivism as a method of norm-identification and the role of methodological nationalism over the study of the history of international law in the modern foundational period of international law. This is extended by an examination of how this bequeathed a double exclusionary bias regarding time and space to the study of the history of international law as well as a reiterative focus on a series of canonical events and authors to the exclusion of others such as those related to the Islamic history of international law. In the second section, the analysis turns to address why this state of historiographical affairs is changing, specifically highlighting intra-disciplinary developments within the field of the history of international law and the effects that the “international turn in the writing of history” is having on the writing of a new history of international law for a global age. The conclusion reflects on some of the tasks ahead by providing a series of historiographical signposts for the history of international law as a field of new research

    Control of a two-dimensional electron gas on SrTiO3(111) by atomic oxygen

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    We report on the formation of a two-dimensional electron gas (2DEG) at the bare surface of (111) oriented SrTiO3. Angle resolved photoemission experiments reveal highly itinerant carriers with a 6-fold symmetric Fermi surface and strongly anisotropic effective masses. The electronic structure of the 2DEG is in good agreement with self-consistent tight-binding supercell calculations that incorporate a confinement potential due to surface band bending. We further demonstrate that alternate exposure of the surface to ultraviolet light and atomic oxygen allows tuning of the carrier density and the complete suppression of the 2DEG.Comment: 5 pages, 4 figure
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