17,588 research outputs found
Women-Loving-Women Portrayals in Fiction, a Critical Literature Review
Indiana University-Purdue University Indianapolis (IUPUI)This critical literature review explores the ways in which scholars have discussed depictions of fictional women-loving women (WLW) in film and on television in the past five years. This study is guided by both sexual script theory and the intersectional perspective. Prior studies of WLW in fiction have largely focused on the areas of homonormativity, race, bisexual-erasure, WLW stereotypes, gender dynamics, WLW communities, and post-modern representation. Earlier research has focused on those areas to the exclusion of giving more attention to exploring the use of queerbaiting in modern storytelling. Future research should include analyses of more recently featured fictional WLW characters and WLW relationships in film and on television in addition to more research on queerbaiting overall
Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress.
Mitochondrial dysfunction has been implicated in human diseases, including cancer, and proposed to accelerate aging. The Drosophila Cyclin-dependent protein kinase complex cyclin D/cyclin-dependent kinase 4 (CycD/Cdk4) promotes cellular growth by stimulating mitochondrial biogenesis. Here, we examine the neurodegenerative and aging consequences of altering CycD/Cdk4 function in Drosophila. We show that pan-neuronal loss or gain of CycD/Cdk4 increases mitochondrial superoxide, oxidative stress markers, and neurodegeneration and decreases lifespan. We find that RNAi-mediated depletion of the mitochondrial transcription factor, Tfam, can abrogate CycD/Cdk4's detrimental effects on both lifespan and neurodegeneration. This indicates that CycD/Cdk4's pathological consequences are mediated through altered mitochondrial function and a concomitant increase in reactive oxygen species. In support of this, we demonstrate that CycD/Cdk4 activity levels in the brain affect the expression of a set of 'oxidative stress' genes. Our results indicate that the precise regulation of neuronal CycD/Cdk4 activity is important to limit mitochondrial reactive oxygen species production and prevent neurodegeneration
Narrative coherence in multiple forensic interviews with child witnesses alleging physical and sexual abuse
This study investigated the narrative coherence of children's accounts elicited in multiple forensic interviews. Transcriptions of 56 police interviews with 28 children aged 3–14 years alleging physical and sexual abuse were coded for markers of completeness, consistency and connectedness. We found that multiple interviews increased the completeness of children's testimony, containing on average almost twice as much new information as single interviews, including crucial location, time and abuse‐related details. When both contradictions within the same interview and across interviews were considered, contradictions were not more frequent in multiple interviews. The frequency of linguistic markers of connectedness remained stable across interviews. Multiple interviews increase the narrative coherence of children's testimony through increasing their completeness without necessarily introducing contradictions or decreasing causal‐temporal connections between details. However, as ‘ground truth’ is not known in field studies, further investigation of the relationship between the narrative coherence and accuracy of testimonies is required
Examining the Role of Environment in a Comprehensive Sample of Compact Groups
(Abridged) Compact groups, with their high number densities, small velocity
dispersions, and an interstellar medium that has not been fully processed,
provide a local analog to conditions of galaxy interactions in the earlier
universe. The frequent and prolonged gravitational encounters that occur in
compact groups affect the evolution of the constituent galaxies in a myriad of
ways, for example gas processing and star formation. Recently, a statistically
significant "gap" has been discovered mid-infrared IRAC colorspace of compact
group galaxies. This gap is not seen in field samples and is a new example of
how the compact group environment may affect the evolution of member galaxies.
In order to investigate the origin and nature of this gap, we have compiled a
sample of 49 compact groups. We find that a statistically significant deficit
of galaxies in this gap region of IRAC colorspace is persistant in this sample,
lending support to the hypothesis that the compact group environment inhibits
moderate SSFRs. We note a curvature in the colorspace distribution, which is
fully consistent with increasing dust temperature as the activity in a galaxy
increases. This full sample of 49 compact groups allows us to subdivide the
data according to physical properties of the groups. An analysis of these
subsamples indicates that neither projected physical diameter nor density show
a trend in colorspace within the values represented by this sample. We
hypothesize that the apparent lack of a trend is due to the relatively small
range of properties in this sample. Thus, the relative influence of stochastic
effects becomes dominant. We analyze spectral energy distributions of member
galaxies as a function of their location in colorspace and find that galaxies
in different regions of MIR colorspace contain dust with varying temperatures
and/or PAH emission.Comment: 24 pages, 13 figures. Accepted for publication in The Astronomical
Journa
A weakly correlated Fermi liquid state with a small Fermi surface in lightly doped SrIrO
We characterize the electron doping evolution of
(SrLa)IrO by means of angle-resolved photoemission.
Concomitant with the metal insulator transition around we find
the emergence of coherent quasiparticle states forming a closed small Fermi
surface of volume , where is the independently measured La
concentration. The quasiparticle weight remains large along the entire
Fermi surface, consistent with the moderate renormalization of the low-energy
dispersion. This indicates a conventional, weakly correlated Fermi liquid state
with a momentum independent residue in lightly doped
SrIrO$_7&.Comment: 5 pages, 4 figure
Revealing natural relationships among arbuscular mycorrhizal fungi: culture line BEG47 represents Diversispora epigaea, not Glomus versiforme
Background: Understanding the mechanisms underlying biological phenomena, such as evolutionarily conservative trait inheritance, is predicated on knowledge of the natural relationships among organisms. However, despite their enormous ecological significance, many of the ubiquitous soil inhabiting and plant symbiotic arbuscular mycorrhizal fungi (AMF, phylum Glomeromycota) are incorrectly classified.
Methodology/Principal Findings:
Here, we focused on a frequently used model AMF registered as culture BEG47. This fungus is a descendent of the ex-type culture-lineage of Glomus epigaeum, which in 1983 was synonymised with Glomus versiforme. It has since then been used as ‘G. versiforme BEG47’. We show by morphological comparisons, based on type material, collected 1860–61, of G. versiforme and on type material and living ex-type cultures of G. epigaeum, that these two AMF species cannot be conspecific, and by molecular phylogenetics that BEG47 is a member of the genus Diversispora.
Conclusions: This study highlights that experimental works published during the last >25 years on an AMF named ‘G. versiforme’ or ‘BEG47’ refer to D. epigaea, a species that is actually evolutionarily separated by hundreds of millions of years from all members of the genera in the Glomerales and thus from most other commonly used AMF ‘laboratory strains’. Detailed redescriptions substantiate the renaming of G. epigaeum (BEG47) as D. epigaea, positioning it systematically in the order Diversisporales, thus enabling an evolutionary understanding of genetical, physiological, and ecological traits, relative to those of other AMF. Diversispora epigaea is widely cultured as a laboratory strain of AMF, whereas G. versiforme appears not to have been cultured nor found in the field since its original description
Myosin V passing over Arp2/3 junctions: branching ratio calculated from the elastic lever arm model
Myosin V is a two-headed processive motor protein that walks in a
hand-over-hand fashion along actin filaments. When it encounters a filament
branch, formed by the Arp2/3 complex, it can either stay on the straight mother
filament, or switch to the daughter filament. We study both probabilities using
the elastic lever arm model for myosin V. We calculate the shapes and bending
energies of all relevant configurations in which the trail head is bound to the
actin filament before Arp2/3 and the lead head is bound either to the mother or
to the daughter filament. Based on the assumption that the probability for a
head to bind to a certain actin subunit is proportional to the Boltzmann factor
obtained from the elastic energy, we calculate the mother/daughter filament
branching ratio. Our model predicts a value of 27% for the daughter and 73% for
the mother filament. This result is in good agreement with recent experimental
data.Comment: 9 pages, 7 figures, to appear in Biophysical Journa
Quasiparticle dynamics and spin-orbital texture of the SrTiO3 two-dimensional electron gas
Two-dimensional electron gases (2DEGs) in SrTiO have become model systems
for engineering emergent behaviour in complex transition metal oxides.
Understanding the collective interactions that enable this, however, has thus
far proved elusive. Here we demonstrate that angle-resolved photoemission can
directly image the quasiparticle dynamics of the -electron subband ladder of
this complex-oxide 2DEG. Combined with realistic tight-binding supercell
calculations, we uncover how quantum confinement and inversion symmetry
breaking collectively tune the delicate interplay of charge, spin, orbital, and
lattice degrees of freedom in this system. We reveal how they lead to
pronounced orbital ordering, mediate an orbitally-enhanced Rashba splitting
with complex subband-dependent spin-orbital textures and markedly change the
character of electron-phonon coupling, co-operatively shaping the low-energy
electronic structure of the 2DEG. Our results allow for a unified understanding
of spectroscopic and transport measurements across different classes of
SrTiO-based 2DEGs, and yield new microscopic insights on their functional
properties.Comment: 10 pages including supplementary information, 4+4 figure
The Shifting Origins of International Law
Both state-centrism and Euro-centrism are under challenge in international law today and this double challenge, this work argues, is being fruitfully mirrored back into the study of the history of international law. It examines, in the first section, the effects of the rise of positivism as a method of norm-identification and the role of methodological nationalism over the study of the history of international law in the modern foundational period of international law. This is extended by an examination of how this bequeathed a double exclusionary bias regarding time and space to the study of the history of international law as well as a reiterative focus on a series of canonical events and authors to the exclusion of others such as those related to the Islamic history of international law. In the second section, the analysis turns to address why this state of historiographical affairs is changing, specifically highlighting intra-disciplinary developments within the field of the history of international law and the effects that the “international turn in the writing of history” is having on the writing of a new history of international law for a global age. The conclusion reflects on some of the tasks ahead by providing a series of historiographical signposts for the history of international law as a field of new research
Control of a two-dimensional electron gas on SrTiO3(111) by atomic oxygen
We report on the formation of a two-dimensional electron gas (2DEG) at the
bare surface of (111) oriented SrTiO3. Angle resolved photoemission experiments
reveal highly itinerant carriers with a 6-fold symmetric Fermi surface and
strongly anisotropic effective masses. The electronic structure of the 2DEG is
in good agreement with self-consistent tight-binding supercell calculations
that incorporate a confinement potential due to surface band bending. We
further demonstrate that alternate exposure of the surface to ultraviolet light
and atomic oxygen allows tuning of the carrier density and the complete
suppression of the 2DEG.Comment: 5 pages, 4 figure
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