Changing clinical and therapeutic trends in tentorial dural arteriovenous fistulas: a systematic review

BACKGROUND AND PURPOSE: Tentorial dural arteriovenous fistulas are characterized by a high hemorrhagic risk. We evaluated trends in outcomes and management of tentorial dural arteriovenous fistulas and performed a meta-analysis evaluating clinical and angiographic outcomes by treatment technique. MATERIALS AND METHODS: We performed a comprehensive literature search for studies on surgical and endovascular treatment of tentorial dural arteriovenous fistulas. We compared the proportion of patients undergoing endovascular, surgical, and combined endovascular/surgical management; the proportion of patients presenting with ruptured tentorial dural arteriovenous fistulas; and proportion of patients with good neurologic outcome across 3 time periods: 1980-1995, 1996-2005, and 2006-2014. We performed a random-effects meta-analysis, evaluating the rates of occlusion, long-term good neurologic outcome, perioperative morbidity, and resolution of symptoms for the 3 treatment modalities. RESULTS: Twenty-nine studies with 274 patients were included. The proportion of patients treated with surgical treatment alone decreased from 38.7% to 20.4% between 1980-1995 and 2006-2014. The proportion of patients treated with endovascular therapy alone increased from 16.1% to 48.0%. The proportion of patients presenting with ruptured tentorial dural arteriovenous fistulas decreased from 64.4% to 43.6%. The rate of good neurologic outcome increased from 80.7% to 92.9%. Complete occlusion rates were highest for patients receiving multimodality treatment (84.0%; 95% CI, 72.0%-91.0%) and lowest for endovascular treatment (71.0%; 95% CI, 56.0%-83.0%; P < .01). Long-term good neurologic outcome was highest in the endovascular group (89.0%; 95% CI, 80.0%-95.0%) and lowest for the surgical group (73.0%; 95% CI, 51.0%-87.0%; P < .03). CONCLUSIONS: Patients with tentorial dural arteriovenous fistulas are increasingly presenting with unruptured lesions, being treated endovascularly, and experiencing higher rates of good neurologic outcomes. Endovascular treatment was associated with superior neurologic outcomes but lower occlusion rate

Updating radical ring-opening polymerisation of cyclic ketene acetals from synthesis to degradation

Radical ring-opening polymerisation (RROP) of cyclic ketene acetals (CKAs) has gained momentum as it yields polyesters as biodegradable polymers from a radical polymerisation. In order to advance the polymerisation, some of its major limitations were addressed in the research presented, focussing on the four mainly used CKAs in modern research on RROP. Monomer synthesis has been updated towards a cobalt/TMSCl-based system that was performed reliably on several monomers at room temperature. Calculations using the density functional theory (DFT) revealed that the ring-opening step is energetically hampered in comparison to a ring-retaining reaction, which explained the challenges faced to promote the ring-opening reaction. Higher molecular weights up to four times the values reached by thermally initiated polymerisation were obtained by exploiting UV light and ultrasound as alternative methods to facilitate the polymerisation. The reaction procedure also influenced thermal properties of the polymers, which in turn affected the enzymatic degradation of nanoparticles based on those polymers. Altogether, the present study offers a holistic update to enhance the RROP of CKAs

Bi-directional Beams Waveguide Slotted Antenna at Millimeter Wave

This paper focused on designing a bi-directional beams waveguide slotted antenna at millimetre wave spectrum. Waveguide slotted antenna is known for its highly directional pattern. By having bi-directional pattern, the capacity of system coverage can be expanded. The design is implemented by using antenna slot theory on a waveguide structure. The slotted are made on two wall surfaces and the performance is compared to the slotted on single wall. The two models designs are simulated using Computer Simulation Technology (CST) microwave software. The simulation results show that both models operate at 30 GHz with minimum reflection coefficient of -24.63 and -25.01 dB respectively. The two models achieved a fair high gain at 15.5 dB and 13.3 dB with directional beamwidth of 8.9 degree. The proposed bi-directional beams structure achieved a comparable gain in both directions when compared to the single direction

Local and global stability of equilibria for a class of chemical reaction networks

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated are characterized primarily by the existence of a certain factorization of their stoichiometric matrix and strong connectedness of an associated graph. Only very mild assumptions are made about the rates of reactions, and, in particular, mass action kinetics are not assumed. In many cases, local asymptotic stability can be extended to global asymptotic stability of each positive equilibrium relative to its stoichiometry class. The results are proved via the construction of Lyapunov functions whose existence follows from the fact that the reaction networks define monotone dynamical systems with increasing integrals

Low loss waveguide-based Butler matrix with iris coupling control method for millimeterwave applications

This paper proposes a low loss 4×4 Butler matrix based on rectangular waveguide cavity resonators technology for millimeterwave beamforming network using iris coupling method. This method has the advantage of controlling the electrical fields and the coupling factor inside a complex medium such as waveguide cavity resonators. The coupling factor of 6 dB for 4×4 Butler matrix is achieved by tuning the iris coupling k-value between the waveguide cavity resonators. Thus, avoiding a higher phase difference losses and component losses at upper millimeterwave bands. To validate the proposed method, CST software simulations are performed under several iris coupling k-values to achieve a 6 dB coupling factor. Then, the proposed 4×4 Butler matrix is 3D metal printed using selective laser melting (SLM) technique. The measured reflection and isolation coefficients are observed below −10 dB, with coupling coefficients ranging between −6 and −7 dB. The phase differences of −42.02°, 42.02°, −130.95°, and 133.3° are achieved at the outputs. It confirmed that using this proposed method has the superiority over the conventional microstrip and waveguide coupling methods by a 1 dB coupling factor loss and a 3° phase difference error

Artificial dielectric optical structures: A challenge for nanofabrication

Diffractive optical components can be made using multiple level kinoforms or single level artificial dielectric structures. The latter require the fabrication of pillars of equal depth but differing width and spacing. As a demonstration device, the diffractive optic equivalent of a wedge has been made in GaAs for use at 1.15 μm. The need for all pillars to have the same height was met by using a selective etch and a very thin etch-stop layer on AlGaAs. The experimental diffraction efficiency was 87.8%, among the best ever obtained and close to the theoretical maximum of 97.6%. © 1998 American Vacuum Society

Fitness costs associated with infections of secondary endosymbionts in the cassava whitefly species Bemisia tabaci

We investigated the dual effects of bacterial infections and diseased cassava plants on the fitness and biology of the Bemisia tabaci infesting cassava in Africa. Isofemale B. tabaci colonies of sub-Saharan Africa 1-subgroup 3 (SSA1-SG3), infected with two secondary endosymbiotic bacteria Arsenophonus and Rickettsia (AR+) and those free of AR infections (AR-) were compared for fitness parameters on healthy and East African cassava mosaic virus-Uganda variant (EACMV-UG) infected cassava plants. The whitefly fecundity and nymph development was not affected by bacterial infections, or the infection of cassava by the virus. However, emergence of adults from nymphs was 50% and 17% higher by AR- on healthy and virus-infected plants, respectively than AR+ flies. Development time of adults also was 10 days longer in AR+ than AR-. The whiteflies were further compared for acquisition and retention of East African cassava mosaic virus-Uganda (EACMV-UG). Higher proportion of AR- acquired (91.8%) and retained (87.6%) the virus than AR+ (71.8%, 61.2%, respectively). Similarly, the AR- flies retained higher quantities of virus (~9 folds more) than AR+. These results indicated that bacteria-free whiteflies were superior and better transmitters of EACMV-UG, as they had higher adult emergence, quicker life-cycle and better virus retention abilities than those infected with bacteria

Fitness costs associated with infections of secondary endosymbionts in the cassava whitefly species Bemisia tabaci

We investigated the dual effects of bacterial infections and diseased cassava plants on the fitness and biology of the Bemisia tabaci infesting cassava in Africa. Isofemale B. tabaci colonies of sub-Saharan Africa 1-subgroup 3 (SSA1-SG3), infected with two secondary endosymbiotic bacteria Arsenophonus and Rickettsia (AR+) and those free of AR infections (AR-) were compared for fitness parameters on healthy and East African cassava mosaic virus-Uganda variant (EACMV-UG) infected cassava plants. The whitefly fecundity and nymph development was not affected by bacterial infections, or the infection of cassava by the virus. However, emergence of adults from nymphs was 50% and 17% higher by AR- on healthy and virus-infected plants, respectively than AR+ flies. Development time of adults also was 10 days longer in AR+ than AR-. The whiteflies were further compared for acquisition and retention of East African cassava mosaic virus-Uganda (EACMV-UG). Higher proportion of AR- acquired (91.8%) and retained (87.6%) the virus than AR+ (71.8%, 61.2%, respectively). Similarly, the AR- flies retained higher quantities of virus (~9 folds more) than AR+. These results indicated that bacteria-free whiteflies were superior and better transmitters of EACMV-UG, as they had higher adult emergence, quicker life-cycle and better virus retention abilities than those infected with bacteria

Formation of plasma around a small meteoroid: 1. Kinetic theory

This article is a companion to Dimant and Oppenheim [2017] https://doi.org/10.1002/2017JA023963.This paper calculates the spatial distribution of the plasma responsible for radar head echoes by applying the kinetic theory developed in the companion paper. This results in a set of analytic expressions for the plasma density as a function of distance from the meteoroid. It shows that at distances less than a collisional mean free path from the meteoroid surface, the plasma density drops in proportion to 1/R where R is the distance from the meteoroid center; and, at distances much longer than the mean‐free‐path behind the meteoroid, the density diminishes at a rate proportional to 1/R2. The results of this paper should be used for modeling and analysis of radar head echoes.This work was supported by NSF grant AGS-1244842. (AGS-1244842 - NSF

the path to silicon-singlet fission heterojunction devices

Singlet exciton fission is an exciton multiplication process that occurs in certain organic materials, converting the energy of single highly-energetic photons into pairs of triplet excitons. This could be used to boost the conversion efficiency of crystalline silicon solar cells by creating photocurrent from energy that is usually lost to thermalisation. An appealing method of implementing singlet fission with crystalline silicon is to incorporate singlet fission media directly into a crystalline silicon device. To this end, we developed a solar cell that pairs the electron-selective contact of a high-efficiency silicon heterojunction cell with an organic singlet fission material, tetracene, and a PEDOT:PSS hole extraction layer. Tetracene and n-type crystalline silicon meet in a direct organic–inorganic heterojunction. In this concept the tetracene layer selectively absorbs blue-green light, generating triplet pairs that can dissociate or resonantly transfer at the organo-silicon interface, while lower-energy light is transmitted to the silicon absorber. UV photoemission measurements of the organic–inorganic interface showed an energy level alignment conducive to selective hole extraction from silicon by the organic layer. This was borne out by current–voltage measurements of devices subsequently produced. In these devices, the silicon substrate remained well-passivated beneath the tetracene thin film. Light absorption in the tetracene layer created a net reduction in current for the solar cell, but optical modelling of the external quantum efficiency spectrum suggested a small photocurrent contribution from the layer. This is a promising first result for the direct heterojunction approach to singlet fission on crystalline silicon