Историјски и етнолошки утицаји на традиционалну културу Помака у грчкој Тракији

The traditional society of the Pomaks is structured on a series of contrasts which characterize their traditional system of values. The problems they face as much in the boundaries of the Muslim minority of Thrace, as well as in the frames of the wider Greek society of the region have defined their cultural expression.Pomaci su slovenofono muslimansko stanovništvo u Zapadnoj Trakiji, po jeziku i tradicionalnoj kulturi različito od stanovništva muslimanske manjine u Grčkoj. O Pomacima se takođe ne može govoriti kao koherentnoj grupi. Teritorijalna pripadnost povlači jezičke i običajne i socijalne razlike, pa tako se izdvajaju, na primer, Pomaci okruga Rodopa ili Ksanti. Struktura tradicionalne kulture Pomaka zasniva se kontrastima vekovima uobličavanog sistema vrednosti. Njihov sadašnji kulturni izraz otkriva promene proistekle iz simbioze tradicije etniteta ove muslimanske manjine i hrišćanskog grčkog okruženja. Inovacije kod Pomaka, čiji je svakodnevni život organizovan po islamskim moralnim i praktičnim odredbama ispoljavaju se u običajima životnog ciklusa, posebno svadbenim i samrtnim. U intenzitetu promena ispoljava se socijalni momenat izazivajući razlike između Pomaka u seoskim i gradskim sredinama

Greek Proverbial Phrases from Modern Satirical Paraphrases of Texts and Titles of the Greek Orthodox Church

This study presents the phenomenon of satirical paraphrase of ecclesiastical texts, some of which acquired in the passage of time proverbial use in the daily life and communication of the Greeks. The study is focused on: a) proverbial phrases from corruption of liturgical phrases and texts, b) proverbial phrases from the corruption of ecclesiastical ad-ministrative titles of Metropolises and c) metropolitans proverbial phrases from the corruption of hymns and prayers

Mobility, Identity(/ies) and Various Functions of the Urban Space: Case Studies from Belgrade and Athens

Тема броја - Мобилност, идентитет(и) и различите функције урбаног простора: студије случаја из Београда и Атине (ур. Гордана Благојевић и Манолис Г. Варвунис) / Topic of the Issue - Mobility, Identity(/ies) and Various Functions of the Urban Space: Case Studies from Belgrade and Athens (eds. Gordana Blagojević and Manolis G. Varvounis)

Synthesis and Study of 2‑(Pyrrolesulfonylmethyl)‑N‑arylimines: A New Class of Inhibitors for Human Glutathione Transferase A1‑1

Overexpression of human GSTA1-1 in tumor cells is part of MDR mechanisms. We report on the synthesis of 11 pyrrole derivatives as hGSTA1-1 inhibitors starting from 1-methyl-2-[(2-nitrobenzylsulfanyl]-1H-pyrrole. Molecular modeling revealed two locations in the enzyme H binding site: the catalytic primary one accommodating shorter and longer derivatives and the secondary one, where shorter derivatives can occupy. Derivative 9, displaying the highest inhibition and bearing a p-nitroarylimino moiety, and derivative 4, lacking this moiety, were studied kinetically. Derivative 9 binds (Ki(9) = 71 ± 4 μM) at the primary site competitively vs CDNB. Derivative 4 binds (Ki(4) = 135 ± 27 μM) at the primary and secondary sites, allowing the binding of a second molecule (4 or CDNB) leading to formation of unreactive and reactive complexes, respectively. The arylmethylsulfonylpyrrole core structure is a new pharmacophore for hGSTA1-1, whereas its derivative 9 may serve as a lead structure

Organocatalytic Enantioselective Aminoalkylation of Pyrazol-3-ones with Aldimines Generated in Situ from α‐Amido Sulfones

Herein, an efficient asymmetric aminoalkylation of pyrazolones with α-amido sulfones catalyzed by a quinine-derived squaramide in dichloromethane/aqueous media has been established. A variety of chiral amines were obtained with high yields (up to 98%) and excellent enantioselectivities (up to 99% ee). The corresponding products are transformed into optically active acetylated pyrazoles after treatment with Ac2O/Et3N, because of the instability of some adducts. The reaction tolerates a wide range of α-amido sulfones and different pyrazolones

An Update on the Synthesis of Pyrrolo[1,4]benzodiazepines

Pyrrolo[1,4]benzodiazepines are tricyclic compounds that are considered “privileged structures” since they possess a wide range of biological activities. The first encounter with these molecules was the isolation of anthramycin from cultures of Streptomyces, followed by determination of the X-ray crystal structure of the molecule and a study of its interaction with DNA. This opened up an intensive synthetic and biological study of the pyrrolo[2,1-c][1,4]benzodiazepines that has culminated in the development of the dimer SJG-136, at present in Phase II clinical trials. The synthetic efforts have brought to light some new synthetic methodology, while the contemporary work is focused on building trimeric pyrrolo[2,1-c][1,4]benzodiazepines linked together by various heterocyclic and aliphatic chains. It is the broad spectrum of biological activities of pyrrolo[1,2-a][1,4]benzodiazepines that has maintained the interest of researchers to date whereas several derivatives of the even less studied pyrrolo[1,2-d][1,4]benzodiazepines were found to be potent non-nucleoside HIV-1 reverse transcriptase inhibitors. The present review is an update on the synthesis of pyrrolo[2,1-c][1,4]benzodiazepines since the last major review of 2011, while the overview of the synthesis of the other two tricyclic isomers is comprehensive