Awareness, interest, and preferences of primary care providers in using point-of-care cancer screening technology

Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both developed and developing countries. However, new medical technology will not be adopted by medical providers unless it addresses a population’s existing needs and end-users’ preferences. The goals of our study were to assess primary care providers’ level of awareness, interest, and preferences in using POC cancer screening technology in their practice and to provide guidelines to biomedical engineers for future POC technology development. A total of 350 primary care providers completed a one-time self-administered online survey, which took approximately 10 minutes to complete. A $50 Amazon gift card was given as an honorarium for the first 100 respondents to encourage participation. The description of POC cancer screening technology was provided in the beginning of the survey to ensure all participants had a basic understanding of what constitutes POC technology. More than half of the participants (57%) stated that they heard of the term “POC technology” for the first time when they took the survey. However, almost all of the participants (97%) stated they were either “very interested” (68%) or “somewhat interested” (29%) in using POC cancer screening technology in their practice. Demographic characteristics such as the length of being in the practice of medicine, the percentage of patients on Medicaid, and the average number of patients per day were not shown to be associated with the level of interest in using POC. These data show that there is a great interest in POC cancer screening technology utilization among this population of primary care providers and vast room for future investigations to further understand the interest and preferences in using POC cancer technology in practice. Ensuring that the benefits of new technology outweigh the costs will maximize the likelihood it will be used by medical providers and patients

HD 209621: Abundances of neutron-capture elements

High resolution spectra obtained from the Subaru Telescope High Dispersion Spectrograph have been used to update the stellar atmospheric parameters and metallicity of the star HD 209621. We have derived a metallicity of [Fe/H] = -1.93 for this star, and have found a large enhancement of carbon and of heavy elements, with respect to iron. Updates on the elemental abundances of four s-process elements (Y, Ce, Pr, Nd) along with the first estimates of abundances for a number of other heavy elements (Sr, Zr, Ba, La, Sm, Eu, Er, Pb) are reported. The stellar atmospheric parameters, the effective temperature, Teff, and the surface gravity, log g (4500 K, 2.0), are determined from LTE analysis using model atmospheres. Estimated [Ba/Eu] = +0.35, places the star in the group of CEMP-(r+s) stars; however, the s-elements abundance pattern seen in HD 209621 is characteristic of CH stars; notably, the 2nd-peak s-process elements are more enhanced than the first peak s-process elements. HD 209621 is also found to show a large enhancement of the 3rd-peak s-process element lead (Pb) with [Pb/Fe] = +1.88. The relative contributions of the two neutron-capture processes, r- and s- to the observed abundances are examined using a parametric model based analysis, that hints that the neutron-capture elements in HD 209621 primarily originate in s-process.Comment: 16 pages,8 figures. Accepted for publication in MNRA

HE 1015-2050: Discovery of a Hydrogen-deficient carbon star at high galactic latitude

Medium resolution spectral analysis of candidate Faint High Latitude Carbon (FHLC) stars from Hamburg/ESO survey has given us the potential to discover objects of rare types. Two primary spectral characteristics of R Coroanae Borealis (RCB) stars are hydrogen deficiency and weaker CN bands relative to C_{2} bands. They are also characterized by their characteristic location in the J-H, H-K plane with respect to cool carbon stars. From a spectral analysis of a sample of 243 candidate FHLC stars, we have discovered a hydrogen-deficient carbon (HdC) star HE 1015-2050, at high Galactic latitude. A differential analysis of its spectrum with that of the spectrum of U Aquarii (U Aqr), a well-known cool HdC star of RCB type, provides sufficient evidence to put this object in a group same as that of U Aqr. Further, it is shown that HE 1015-2050 does not belong to any of the C-star groups CH, C-R, C-N or C-J. Cool RCB stars form a group of relatively rare astrophysical objects; approximately 51 are known in the Galaxy and some 18 in the Large Magellanic Clouds (LMC) and five in Small Magellanic Cloud (SMC). The present discovery adds a new member to this rare group. Although its spectral characteristics and its location in the J-H vs H-K plane places HE 1015-2050 in the same group to which U Aqr belongs, extended photometric observations would be useful to learn if there is any sudden decline in brightness, this being a characteristic property of HdC stars of RCB type.Comment: 5 pages,3 figure

Abundance analysis of cool extreme helium star: LSS 3378

Abundance analysis of the cool extreme helium (EHe) star LSS 3378 is presented. The abundance analysis is done using LTE line formation and LTE model atmospheres constructed for EHe stars. The atmosphere of LSS 3378 shows evidence of H-burning, He-burning, and s-process nucleosynthesis. The derived abundances of iron-peak and alpha-elements indicate absence of selective fractionation or any other processes that can distort chemical composition of these elements. Hence, the Fe abundance (log epsilon(Fe) = 6.1) is adopted as an initial metallicity indicator. The measured abundances of LSS 3378 are compared with those of R Coronae Borealis (RCB) stars and with rest of the EHe stars as a group.Comment: 7 pages, 4 figures, 3 tables, MNRAS format, accepted for publication in MNRA

Correlation between technetium and lithium in a sample of oxygen-rich AGB variables

The aims of this paper are: 1) to revisit the Tc content of a sample of oxygen-rich asymptotic giant branch (AGB) variables and 2) to increase the number of such stars for which the Li abundance has been measured to provide constraints on theoretical models of extra-mixing processes. To this end, we analysed high-resolution spectra of 18 sample stars for the presence of absorption lines of Tc and Li. The abundance of the latter was determined by comparing the observed spectra to hydrostatic MARCS model spectra. Bolometric magnitudes were established from near-IR photometry and pulsation periods. We reclassify the star V441 Cyg as Tc-rich, and the unusual Mira star R Hya, as well as W Eri, as Tc-poor. The abundance of Li, or an upper limit to it, was determined for all of the sample stars. In all stars with Tc we also detected Li. Most of them have a Li content slightly below the solar photospheric value, except for V441 Cyg, which has ~1000 times the solar abundance. We also found that, similar to Tc, a lower luminosity limit seems to exist for the presence of Li. We conclude that the higher Li abundance found in the cooler and higher luminosity objects could stem from a Li production mechanism operating on the AGB. The stellar mass might have a crucial influence on this (extra-mixing) production mechanism. It was speculated that the declining pulsation period of R Hya is caused by a recent thermal pulse (TP). While not detecting Tc does not rule out a TP, it indicates that the TPs are not strong enough to drive dredge-up in R Hya. V441 Cyg, on the other hand, could either be a low-mass, intrinsic S-star that produced its large amount of Li by extra-mixing processes, or an intermediate-mass star (M>=M_sun) undergoing Li production due to hot bottom burning.Comment: 12 pages, 7 figures, accepted for publication in A&

A Survey of the Student Attitudes Toward Woodworking Technology at F. E. Kellam High School

The problems of this study was to determine the reason or reasons behind the selection of woods technology by those students who were fulfilling an elective course credit at Kellam High School. Among those ideas that were being examined were 1) the student\u27s attraction to the material and the product that results from the material; 2) other influences such as parents, peers, and school counselors; 3) to what degree does occupational or vocational intent interest the student

Abundances of neutron-capture elements in G 24-25. A halo-population CH subgiant

The differences between the neutron-capture element abundances of halo stars are important to our understanding of the nucleosynthesis of elements heavier than the iron group. We present a detailed abundance analysis of carbon and twelve neutron-capture elements from Sr up to Pb for a peculiar halo star G24-25 with [Fe/H] = -1.4 in order to probe its origin. The equivalent widths of unblended lines are measured from high resolution NOT/FIES spectra and used to derive abundances based on Kurucz model atmospheres. In the case of CH, Pr, Eu, Gd, and Pb lines, the abundances are derived by fitting synthetic profiles to the observed spectra. Abundance analyses are performed both relative to the Sun and to a normal halo star G16-20 that has similar stellar parameters as G24-25. We find that G24-25 is a halo subgiant star with an unseen component. It has large overabundances of carbon and heavy s-process elements and mild overabundances of Eu and light s-process elements. This abundance distribution is consistent with that of a typical CH giant. The abundance pattern can be explained by mass transfer from a former asymptotic giant branch component, which is now a white dwarf.Comment: 11 pages, 9 figures, accepted for publication in A&

Near-Infrared photometry and spectroscopy of NGC 6539 and UKS 1: two intermediate metallicity Bulge Globular Clusters

Using the SofI imager at ESO/NTT and NIRSPEC spectrograph at KeckII, we have obtained J,K images and echelle spectra covering the range 1.5 - 1.8 micron for the intermediate metallicity Bulge globular clusters NGC6539 and UKS1. We find [Fe/H]=-0.76 and -0.78, respectively, and an average alpha-enhancement of +0.44 dex and +0.31 dex, consistent with previous measurements of metal rich Bulge clusters, and favoring the scenario of rapid chemical enrichment. We also measure very low 12C/13C=4.5 +/-1 isotopic ratios in both clusters, suggesting that extra-mixing mechanisms due to cool bottom processing are at work during the evolution along the Red Giant Branch. Finally, we measure accurate radial velocities of =+31 +/-4Km/s and =+57 +/-6Km/s and velocity dispersion of about 8 Km/s and 11 Km/s for NGC6539 and UKS1, respectively.Comment: 10 pages, 7 figures, accepted for publication at MNRA

J-type Carbon Stars in the Large Magellanic Cloud

A sample of 1497 carbon stars in the Large Magellanic Cloud has been observed in the red part of the spectrum with the 2dF facility on the AAT. Of these, 156 have been identified as J-type (i.e. 13C-rich) carbon stars using a technique which provides a clear distinction between J stars and the normal N-type carbon stars that comprise the bulk of the sample, and yields few borderline cases. A simple 2-D classification of the spectra, based on their spectral slopes in different wavelength regions, has been constructed and found to be related to the more conventional c- and j-indices, modified to suit the spectral regions observed. Most of the J stars form a photometric sequence in the K - (J-K) colour magnitude diagram, parallel to and 0.6 mag fainter than the N star sequence. A subset of the J stars (about 13 per cent) are brighter than this J star sequence; most of these are spectroscopically different from the other J stars. The bright J stars have stronger CN bands than the other J stars and are found strongly concentrated in the central regions of the LMC. Most of the rather few stars in common with Hartwick and Cowley's sample of suspected CH stars are J stars. Overall, the proportion of carbon stars identified as J stars is somewhat lower than has been found in the Galaxy. The Na D lines are weaker in the LMC J stars than in either the Galactic J stars or the LMC N stars, and do not seem to depend on temperature.Comment: 19 pages, 21 figures, Latex; in press, MNRA

The evolutionary state of Miras with changing pulsation periods

Context: Miras are long-period variables thought to be in the asymptotic giant branch (AGB) phase of evolution. In about one percent of known Miras, the pulsation period is changing. It has been speculated that this changing period is the consequence of a recent thermal pulse in these stars. Aims: We aim to clarify the evolutionary state of these stars, and to determine in particular whether or not they are in the thermally-pulsing (TP-)AGB phase. Methods: One important piece of information that has been neglected so far when determining the evolutionary state is the presence of the radio-active s-process element technetium (Tc). We obtained high-resolution, high signal-to-noise-ratio optical spectra of a dozen prominent Mira variables with changing pulsation period to search for this indicator of TPs and dredge-up. We also use the spectra to measure lithium (Li) abundances. Furthermore, we establish the evolutionary states of our sample stars by means of their present-day periods and luminosities. Results: Among the twelve sample stars observed in this programme, five were found to show absorption lines of Tc. BH Cru is found to be a carbon-star, its period increase in the past decades possibly having stopped by now. We report a possible switch in the pulsation mode of T UMi from Mira-like to semi-regular variability in the past two years. R Nor, on the other hand, is probably a fairly massive AGB star, which could be true for all meandering Miras. Finally, we assign RU Vul to the metal-poor thick disk with properties very similar to the short-period, metal-poor Miras. Conclusions: We conclude that there is no clear correlation between period change class and Tc presence. The stars that are most likely to have experienced a recent TP are BH Cru and R Hya, although their rates of period change are quite different.Comment: 11 pages, 7 figures, 2 tables; accepted for publication in A&