237 research outputs found

    Compact forms of reduced density matrices

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    10 págs.; 3 tabs.; PACS number~s!: 31.15.Hz, 31.10.1zThe necessary and sufficient minimum information carried by reduced density matrices (RDM) are discussed. A method is reported for obtaining the same information as a p-RDM although in compact form, from which all the redundant information is omitted. The algebra operations and basic properties of these compact-form matrices are obtained. ©2003 The American Physical SocietyWe are greatly indebted to the Spanish Ministerio de Educación, Cultura y Deporte for its support under Project No. BQU2000-1158Peer Reviewe

    Impacts of sea-level rise-induced erosion on the Catalan coast

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    The final publication is available at Springer via http://dx.doi.org/10.1007/s10113-016-1052-xThe Catalan coast as most of the developed Mediterranean coastal zone is characterized by the coincidence of stresses and pressures on the natural system with a high exposure and low adaptive capacity. Due to this, climate change-induced effects will increase natural hazards and aggravate their associated impacts and, in consequence, it is necessary to assess their effects for proper long-term management. In this work, we assess the impact of sea-level rise (SLR)-induced shoreline retreat on the Catalan coast for three scenarios ranging from 0.53 to 1.75 m by the year 2100. Implications are analysed in terms of affectation of two main functions provided by beaches, i.e. recreation and protection. Obtained results show that CC will be a serious threat to analysed functions since the expected enhanced shoreline retreat will severely decrease the recreational carrying capacity and the capacity of protection in the near future under tested scenarios. The actual level of development along the coastal zone reduces the natural resilient capacity of beaches to SLR in such a way that the lack of accommodation space can be identified as a main factor for the estimated impacts.Peer ReviewedPostprint (author's final draft

    Impact of blast morphological alterations and abrrante immunophenotype on relapsed common childhood b lymphoblastic leukemia

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    44 p.La leucemia linfoblástica aguda es el cáncer más común de la infancia, siendo la estirpe de células B la más frecuente. En las dos últimas décadas se han producido grandes avances en su tratamiento, con una tasa de curación que oscila entre el 80-90%. Sin embargo, un 20% de los pacientes sufren una recaída. Los factores pronósticos de recaída más relevantes son enfermedad mínima residual, citogenética, edad, contaje de leucocitos, afectación del sistema nervioso central al diagnóstico e inmunofenotipo. Estos estratifican el riesgo y determinan el tratamiento a seguir. Debido a su importancia y la escasa literatura sobre la morfología aberrante de los blastos y marcadores aberrantes de inmunofenotipo, se ha decidido llevar a cabo este estudio. La hipótesis planteada dicta que determinadas alteraciones morfológicas, y marcadores de inmunofenotipo aberrantes, podrían predecir el riesgo de recaída. Se trata de un estudio de cohortes retrospectiva realizado en una población infantil entre 2013 y 2020 en el Hospital Infantil Universitario Niño Jesús. Se han analizado CD66C+, CD38-, CD52-, CD7.1+, CD33+, CD58 sobreexpresado, CD10 sobreexpresado + CD34-, TLSPR sobreexpresado, CD2+, CD13+ y CD7+. La morfología que se ha analizado ha sido lobulaciones nucleares, vacuolas, prolongaciones citoplasmáticas, condensación cromatínica y microvacuolas. El análisis estadístico realizado con SPSS, mediante regresión logística univariable con una p<0,05 ha mostrado que la expresión de CD66c+, CD33+ y la presencia de prolongaciones citoplasmáticas aumentan el riesgo de recaída. El análisis multivarante ha mostrado que CD66c+, CD33+, y la presencia de condensación cromatínica, aumentan el riesgo de recaída.Acute lymphoblastic leukemia is the most common childhood cancer, with the B-cell lineage being the most common. In the last two decades there have been great advances in its treatment, with a cure rate of between 80-90%. However, 20% of patients suffer a relapse. The most relevant prognostic factors for relapse are minimal residual disease, cytogenetics, age, leukocyte infection, central nervous system involvement at diagnosis, and immunophenotype. These stratify the risk and determine the treatment to be followed. Due to its importance and the scarce literature on aberrant blast morphology and aberrant markers of immunophenotype, it has been decided to carry out this study. The proposed hypothesis dictates that certain morphological alterations and aberrant immunophenotype markers could predict the risk of relapse. This is a retrospective cohort study conducted in a child population between 2013 and 2020 at the Nino Jesus University Children's Hospital. CD66C+, CD38-, CD52-, CD7.1+, CD33+, overexpressed CD58, overexpressed CD10 + CD34-, overexpressed TLSPR, CD2+, CD13+ and CD7+ have been analyzed. The morphology that has been analyzed has been nuclear lobulations, vacuoles, cytoplasmic extensions, chromatin condensation and microvacuoles. The statistical analysis carried out with SPSS, using univariate logistic regression with p<0.05, has shown that the expression of CD66c+, CD33+ and the presence of cytoplasmic extensions increases the risk of relapse. Multivariate analysis has shown that CD66c+, CD33+, and the presence of chromatin condensation increase the risk of relapse.Grado en Medicin

    N-representability problem within the framework of the contracted Schrödinger equation

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    A a procedure is proposed by which, in the course of an iterative solution of the second-order contracted Schrödinger equation, The N representability of the second-order reduced density matrix can be tested with increasing stringency. This procedure was suggested by an extended study of the G conditions and from the contraction into the two-electron space of an N-fermion relation, expressing in matrix form the antisymmetry and normalization properties of the N-electron wave function. Several relations are reported.This work was supported by de Dirección General de Investigación Científica y Técnica del Ministerio de Educación y Ciencia under Project nº PB96-0891.Peer Reviewe

    Tratamiento de la drogadicción de larga duración y ontoterapia. A propósito de tres casos

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    Los autores analizan, a partir de tres casos, factores clínicos, sociales, temperamentales y situacionales en pacientes drogodependientes de larga duración. Se valora especialmente la importancia que tiene el hecho que el consumo de drogas empiece en la adolescencia pues esto di? culta signi? cativamente la creación de relaciones sociales y laborales estables. Además, las di? cultades de adaptación son especialmente graves cuando los pacientes han llegado a una edad cercana o superior a los 30 años sin haber dejado de consumir drogas. El análisis fenomenológico-histórico nos lleva a la conclusión de que en muchos casos si no hay una conciencia re? exiva centrada en un proyecto vital, el tratamiento suele fracasar. La posibilidad de realizar un tratamiento ontoterápico ha de valorarse como un paso importante para evaluar las posibilidades fiables de curación en pacientes consumidores de larga duración

    The Tordera Delta, a hotspot to storm impacts in the coast northwards of Barcelona (NW Mediterranean)

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    The Catalan coast, as most of the developed Mediterranean coastal zone, can be characterized as a high-risk area to the impact of storms due to the large concentration of values together with the dominance of eroding shorelines. In consequence, any long-term coastal management scheme must include a risk analysis to permit decision makers to better allocate resources. This can be done in a nested approach in which hotspots are first identified along the coast at a regional scale and secondly, they are further analysed to produce dedicated risk reduction strategies. In this work, we apply the methodology developed within the RISC-KIT project for identifying and analysing coastal hotspots in the Catalan coast as a test for applying it to Mediterranean conditions. Obtained results show that this methodology is very efficient in identifying hotspots of storm-induced flooding and erosion at a regional scale. The adoption of the response approach resulted in the direct assessment of the hazards' probability distributions, which allowed for the selection of the severity of the hotspots to be identified. When a given coastal stretch behaves as a hotspot for both hazards, it is identified as a very highly-sensitive area to storm impacts. In the study area, the Tordera Delta possesses this condition of very high “hotspotness.” This has been demonstrated by the large and frequent damages suffered by the site during the past decades. The paper analyses different aspects related to the risk management of this area, including stakeholder actions.Peer ReviewedPostprint (published version
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