17 research outputs found

    Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis

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    [Purpose]: We explored the cross-sectional association between the adherence to three different provegetarian (PVG) food patterns defined as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. [Methods]: We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus randomized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fish and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and coffee/fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them differently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. [Results]: A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefficients for 5th vs. 1st quintile were − 0.16 (95% CI: − 0.33 to 0.01) for gPVG (p trend: 0.015), and − 0.23 (95% CI: − 0.41 to − 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). [Conclusion]: Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk.This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (six coordinated FIS projects leaded by JS-S and JVi, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158); the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to JS-S; the European Research Council (Advanced Research Grant 2014–2019; agreement #340918) granted to MÁM-G.; the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 grant from the Generalitat Valenciana; the SEMERGEN grant; None of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication

    Outpatient Parenteral Antibiotic Treatment vs Hospitalization for Infective Endocarditis: Validation of the OPAT-GAMES Criteria

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    Equipamiento logopédico para personas con discapacidades psíquicas severas

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    El proyecto ha sido realizado por diferentes estudiantes de ingeniería electrónica, eléctrica y de diseño, utilizando metodologías ágiles para la gestión del equipo. Este Trabajo Final de Grado presenta el diseño y la implementación de material logopédico para la fundación Ave María que es un centro que se encarga del cuidado de personas con discapacidad psíquica severa. Todo ello se ha llevado a cabo a través del Instituto de Robótica para la Dependencia de Sitges que colabora con esta fundación. Para el desarrollo del material logopédico se ha utilizado la metodología del design thinking para crear el diseño más óptimo posible para los usuarios a los que va dirigido. Para alcanzar el objetivo de su implementación se ha dividido el trabajo en varios capítulos. En el primer capítulo, se ha llevado a cabo un estudio del estado del arte para conocer el entorno en el que se trabaja y el estado actual de la tecnología para este tipo de personas con discapacidades psíquicas. En el segundo capítulo, se ha realizado el trabajo de campo en la fundación Ave María mediante entrevistas, visitas al centro, encuestas y observaciones de los usuarios interactuando con material logopédico a través de vídeos. A partir de ello, se ha creado una lista de soluciones de los dos apartados realizados anteriormente y de esta manera, se definen las necesidades más importantes que tiene que cubrir el producto a implementar. El tercer capítulo contiene la primera solución adoptada, en concreto se trata de la mejora de una espaldera interactiva que ya está en uso en la fundación. El capítulo explica las propuestas presentadas para la mejora de este equipamiento, teniendo en cuenta los requisitos adquiridos en el trabajo de campo como son la estimulación visual y auditiva a los usuarios o eliminar elementos conflictivos de la antigua espaldera. Además de justificar la solución adoptada, el capítulo detalla la funcionalidad del producto, su evolución a nivel electrónico, eléctrico y de diseño y el producto final en cuestión. El cuarto capítulo, contiene una segunda mejora de un equipamiento del centro propuesto por el Instituto de Robótica a partir de las reuniones realizadas a lo largo del proyecto. Este capítulo busca estudiar cómo regular la altura de un sistema ya en funcionamiento llamado Armoni. Este sistema consiste en un una pantalla con la que los usuarios pueden realizar diferentes actividades para su mejora cognitiva. Esta pantalla está acoplada a una mesa, la cual para regular su altura en función del paciente que la utiliza, se tiene que hacer de forma manual. Por tanto, se exponen las diferentes propuestas de mejora, la solución adoptada, su funcionalidad y los requisitos necesarios para integrarlo en un futuro sistema mecánico, así como estudio del sistema eléctrico necesario para la regulación de la altura. El último capítulo, detalla la gestión realizada del proyecto en cuanto a evolución del equipo, teniendo en cuenta los autores que han participado, los contratiempos que han surgido y las soluciones adoptadas para su desarrollo. Finalmente, se redactan las conclusiones de las dos mejoras en las que el equipo ha estado trabajando, unas conclusiones generales del proyecto y una descripción de posibles futuras líneas de trabajo

    Equipamiento logopédico para personas con discapacidades psíquicas severas

    No full text
    El proyecto ha sido realizado por diferentes estudiantes de ingeniería electrónica, eléctrica y de diseño, utilizando metodologías ágiles para la gestión del equipo. Este Trabajo Final de Grado presenta el diseño y la implementación de material logopédico para la fundación Ave María que es un centro que se encarga del cuidado de personas con discapacidad psíquica severa. Todo ello se ha llevado a cabo a través del Instituto de Robótica para la Dependencia de Sitges que colabora con esta fundación. Para el desarrollo del material logopédico se ha utilizado la metodología del design thinking para crear el diseño más óptimo posible para los usuarios a los que va dirigido. Para alcanzar el objetivo de su implementación se ha dividido el trabajo en varios capítulos. En el primer capítulo, se ha llevado a cabo un estudio del estado del arte para conocer el entorno en el que se trabaja y el estado actual de la tecnología para este tipo de personas con discapacidades psíquicas. En el segundo capítulo, se ha realizado el trabajo de campo en la fundación Ave María mediante entrevistas, visitas al centro, encuestas y observaciones de los usuarios interactuando con material logopédico a través de vídeos. A partir de ello, se ha creado una lista de soluciones de los dos apartados realizados anteriormente y de esta manera, se definen las necesidades más importantes que tiene que cubrir el producto a implementar. El tercer capítulo contiene la primera solución adoptada, en concreto se trata de la mejora de una espaldera interactiva que ya está en uso en la fundación. El capítulo explica las propuestas presentadas para la mejora de este equipamiento, teniendo en cuenta los requisitos adquiridos en el trabajo de campo como son la estimulación visual y auditiva a los usuarios o eliminar elementos conflictivos de la antigua espaldera. Además de justificar la solución adoptada, el capítulo detalla la funcionalidad del producto, su evolución a nivel electrónico, eléctrico y de diseño y el producto final en cuestión. El cuarto capítulo, contiene una segunda mejora de un equipamiento del centro propuesto por el Instituto de Robótica a partir de las reuniones realizadas a lo largo del proyecto. Este capítulo busca estudiar cómo regular la altura de un sistema ya en funcionamiento llamado Armoni. Este sistema consiste en un una pantalla con la que los usuarios pueden realizar diferentes actividades para su mejora cognitiva. Esta pantalla está acoplada a una mesa, la cual para regular su altura en función del paciente que la utiliza, se tiene que hacer de forma manual. Por tanto, se exponen las diferentes propuestas de mejora, la solución adoptada, su funcionalidad y los requisitos necesarios para integrarlo en un futuro sistema mecánico, así como estudio del sistema eléctrico necesario para la regulación de la altura. El último capítulo, detalla la gestión realizada del proyecto en cuanto a evolución del equipo, teniendo en cuenta los autores que han participado, los contratiempos que han surgido y las soluciones adoptadas para su desarrollo. Finalmente, se redactan las conclusiones de las dos mejoras en las que el equipo ha estado trabajando, unas conclusiones generales del proyecto y una descripción de posibles futuras líneas de trabajo

    Cross‐cultural adaptation of the FRAIL scale for critically ill patients in Spain

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    Abstract Aim To translate and culturally adapt the FRAIL scale into Spanish and perform a preliminary test of diagnostic accuracy in patients admitted to intensive care units. Design Cross‐sectional diagnostic study. Methods Five intensive care units (ICU) in Spain were participated. Stage 1: Three native Spanish‐speaking bilingual translators familiar with the field of critical care translated the scale from English into Spanish. Stage 2: Three native English‐speaking bilingual translators familiar with critical care medicine. Stage 3: Authors of the original scale compared the English original and back‐translated versions of the scale. Stage 4: Five nurses with more than 5 years of ICU experience and five critical care physicians assessed the comprehension and relevance of each of the items of the Spanish version in 30 patients of 3 different age ranges (65 years). Results The FRAIL scale was translated and adapted cross‐culturally for patients admitted to intensive care units in Spain. The process consisted of four stages: translation, back translation, comparison and pilot test. There was good correspondence between the original scale and the Spanish version in 100% of the items. The participating patients assessed the relevance (content validity) and comprehensibility (face validity) of each of the items of the first Spanish version. The relevance of some of the items scored low when the scale was used in patients younger than 65 years. Conclusions We have cross‐culturally adapted the FRAIL scale, originally in English, to Spanish for its use in the critical care medical setting in Spanish‐speaking countries. Implications for Professionals Physicians and nurses can apply the new scale to all patients admitted to the intensive care units. Nursing care can be adapted according to frailty, trying to reduce the side effects of admission to these units for the most fragile patients. Reporting Method The manuscript's authors have adhered to the EQUATOR guidelines, using the COSMIN reporting guideline for studies on the measurement properties of patient‐reported outcome measures. Patient or Public Contribution In a pilot clinical study, we applied the first version of the FRAIL‐Spain scale to intensive care unit (ICU) patients. Five nurses with more than 5 years of ICU experience and five critical care physicians assessed the relevance (content validity) and comprehensibility (face validity) of the five items of the first Spanish version. Relevance was assessed using a 4‐point Likert scale ranging from 1 (no relevance) to 4 (high relevance), and comprehensibility was assessed as poor, acceptable or good. Each health professional applied the scale to three patients (total number of patients = 30) of three different age ranges (65 years) and recorded the time of application of the scale to each patient. Although the frailty scales were initially created by geriatricians to be applied to the elders, there is little experience with their application in critically ill patients of any age. Therefore, more information is needed to determine the relevance of using this scale in critical care patients. In this pilot study, we considered that nurses and critical care physicians should evaluate frailty using this adapted scale in adult patients admitted to the Intensive Care Units

    Pro‑vegetarian food patterns and cardiometabolic risk in the PREDIMED‑Plus study: a cross‑sectional baseline analysis

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    LThis work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (six coordinated FIS projects leaded by JS-S and JVi, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158); the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant to JS-S; the European Research Council (Advanced Research Grant 2014-2019; agreement #340918) granted to MAM-G.; the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the Consejeria de Salud de la Junta de Andalucia (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 grant from the Generalitat Valenciana; the SEMERGEN grant; None of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication.Purpose We explored the cross-sectional association between the adherence to three different provegetarian (PVG) food patterns defined as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. Methods We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus randomized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/ grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fish and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and coffee/ fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them differently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. Results A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefficients for 5th vs. 1st quintile were − 0.16 (95% CI: − 0.33 to 0.01) for gPVG (p trend: 0.015), and − 0.23 (95% CI: − 0.41 to − 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). Conclusion Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk.official Spanish InstitutionsCIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN)Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS)European Commission PI13/00673 PI13/00492 PI13/00272 PI13/01123 PI13/00462 PI13/00233 PI13/02184 PI13/00728 PI13/01090 PI13/01056 PI14/01722 PI14/00636 PI14/00618 PI14/00696 PI14/01206 PI14/01919 PI14/00853 PI14/01374The European Regional Development Fund PI14/00972 PI14/00728 PI14/01471 PI16/00473 PI16/00662 PI16/01873 PI16/01094 PI16/00501 PI16/00533 PI16/00381 PI16/00366 PI16/01522 PI16/01120 PI17/00764 PI17/01183 PI17/00855 PI17/01347 PI17/00525 PI17/01827 PI17/00532 PI17/00215European Commission PI17/01441 PI17/00508 PI17/01732 PI17/00926 PI19/00957 PI19/00386 PI19/00309 PI19/01032 PI19/00576 PI19/00017 PI19/01226 PI19/00781 PI19/01560 PI19/01332 PI20/01802 PI20/00138 PI20/01532 PI20/00456 PI20/00339 PI20/00557 PI20/00886 PI20/01158Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grantEuropean Research Council (ERC)European Commission 340918La Caixa Foundation 2013ACUP00194Junta de Andalucia PI0458/2013 PS0358/2016 PI0137/2018Generalitat Valenciana European Commission PROMETEO/2017/017SEMERGEN gran

    Microbial Phenolic Metabolites Are Associated with Improved Cognitive Health<br />

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    Scope: Diets rich in polyphenols has been associated with better cognitive performance. The aim of this study is toassess the relationship between microbial phenolic metabolites (MPM) in urine and cognition in the context of an olderpopulation at high cardiovascular risk.Methods and results: A cross-sectional analysis is conducted in 400 individuals of the PREDIMED-Plus study. Liquidchromatography coupled to mass spectrometry is used to identify urinaryMPM.Mediterranean diet (MedDiet) adherenceis estimated with a 17-item questionnaire and cognitive function is evaluated with a battery of neuropsychological tests.Multivariable-adjusted linear regression models are fitted to assess the relationship of urinary MPM with the MedDietand cognitive tests. Protocatechuic acid and enterolactone glucuronide are associated with higher adherence to theMedDiet. Regarding cognitive function, protocatechuic acid, vanillic acid glucuronide, 3-hydroxybenzoic acid, enterodiolglucuronide, and enterolactone glucuronide are directly associated with a global composite score of all the cognitive tests.Furthermore, protocatechuic acid and enterolactone glucuronide are associated with higher scores in the Mini-MentalState Examination, whereas enterodiol glucuronide is associated with improved Clock Drawing Test scores.Conclusions: These results suggest that the MedDiet is linked to MPM associated with better cognitive performance inan older population.</p

    More Adult Women than Men at High Cardiometabolic Risk Reported Worse Lifestyles and Self-Reported Health Status in the COVID-19 Lockdown

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    Background: The COVID-19 lockdown represented an immense impact on human health, which was characterized by lifestyle and dietary changes, social distancing and isolation at home. Some evidence suggests that these consequences mainly affected women and altered relevant ongoing clinical trials. The aim of this study was to evaluate the status and changes in diet, physical activity (PA), sleep and self-reported health status (SRH) as perceived by older adult men and women with metabolic syndrome during the COVID-19 lockdown. Methods: We analyzed data from 4681 Spanish adults with metabolic syndrome. We carried out a telephone survey during May and June 2020 to collect information on demographics, dietary habits, PA, sleep, SRH and anthropometric data. Results: The mean age of participants was 64.9 years at recruitment, and 52% of participants were men. Most participants (64.1%) perceived a decrease in their PA during confinement. Regarding gender-specific differences, a higher proportion of women than men perceived a decrease in their PA (67.5% vs. 61.1%), Mediterranean diet adherence (20.9% vs. 16.8%), sleep hours (30.3% vs. 19.1%), sleep quality (31.6% vs. 18.2%) and SRH (25.9% vs. 11.9%) (all p < 0.001). Conclusions: The COVID-19 lockdown affected women more negatively, particularly their self-reported diet, PA, sleep and health status.This research was funded by Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund [six coordinated FIS projects leaded by J.S.-S. and J.V. (Jesús Vioque), including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158]; the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to J.S.-S.; the Recercaixa [number 2013ACUP00194] grant to J.S.-S.; grants from the Consejería de Salud de la Junta de Andalucía [PI0458/2013, PS0358/2016, PI0137/2018]; the PROMETEO/2017/017 and PROMETEO 2021/021 grants from the Generalitat Valenciana; the SEMERGEN grant. None of the funding sources took part in the design, collection, analysis, interpretation of the data, writing the report or in the decision to submit the manuscript for publication. J.S.-S. is partially supported by ICREA under the ICREA Academia programme. This research was funded by the Community of Madrid and the European Union through the European Regional Development Fund (ERDF)-REACT-EU resources of the Madrid Operational Program 2014–2020, in the action line of R+D+i projects in response to COVID-19, “FACINGLCOVID-CM”
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