Automation and Robotics Used in Hydroponic System

Hydroponic system requires periodic labor, a systematic approach, repetitive motion and a structured environment. Automation, robotics and IoT have allowed farmers to monitoring all the variables in plant, root zone and environment under hydroponics. This research introduces findings in design with real time operating systems based on microcontrollers; pH fuzzy logic control system for nutrient solution in embed and flow hydroponic culture; hydroponic system in combination with automated drip irrigation; expert system-based automation system; automated hydroponics nutrition plants systems; hydroponic management and monitoring system for an intelligent hydroponic system using internet of things and web technology; neural network-based fault detection in hydroponics; additional technologies implemented in hydroponic systems and robotics in hydroponic systems. The above advances will improve the efficiency of hydroponics to increase the quality and quantity of the produce and pose an opportunity for the growth of the hydroponics market in near future

Formación de competencias investigativas en pregrado: su diagnóstico.

The objective of this article is to socialize among the community of university professors the results of the diagnosis of the training of investigative competences of students of the career Logopedia. It is part of the institutional research project «The improvement of educational theory based on the solution of educational problems prioritized in the province of Sancti Spiritus: alternative solutions». In this article, the authors annex the elaborated research instruments that were applied for the diagnosis: guides for the analysis of documents and questionnaires. The diagnosis was made considering the fourth and fifth-year students, as well as a sample of tutors, courts, and opponents of student scientific work. The results are specified in strengths and weaknesses in the training of investigative skills, which serve as guidelines for redesigning the methodological conception of scientific work careerO objetivo do seguinte artigo é socializar entre a comunidade de professores universitários, os resultados do diagnóstico da formação de competências investigativas de estudantes da carreira Logopedia. Faz parte do projeto de pesquisa institucional «O aperfeiçoamento da teoria pedagógica em termos da solução de problemas educacionais priorizados na província de Sancti Spíritus: alternativas para a sua solução». Neste artigo, os autores anexam os instrumentos de pesquisa elaborados que foram aplicados para o diagnóstico: guias para análise de documentos e questionários. O diagnóstico foi feito considerando os alunos do quarto e quinto ano, bem como uma amostra de tutores, tribunais e opositores do trabalho científico estudantil. Os resultados são especificados em pontos fortes e fracos na formação de habilidades de investigação, que servirão como diretrizes para o redesenho da concepção metodológica do trabalho científico da carreira.El presente artículo tieme como objetivo socializar entre la comunidad de profesores universitarios, los resultados del diagnóstico de formación de competencias investigativas de estudiantes de la carrera logopedia. Constituye parte del proyecto de investigación institucional "El perfeccionamiento de la teoría pedagógicaen función de la solución de problemas educativos prirozados en la provincia Sancti Spíritus: alternativas para su solución"En este artículo los autores anexan los instrumentos de investigación elaborados que se aplicaron para el diagnóstico: guía para análisis de documentos y cuestionarios. El diagnóstico se efectuó considerando a los estudiantes de cuarto y quinto año, así como una muestra de tutores, oponentes, tribunales de trabajo científico estudiantil. Los resultados se concretan en fortalezas y debilidades en la formación de competencias investigativas, lo que servirá de pautas para el rediseño de la concepción metodológica del trabajo científico de la carrera

Associated factors to non-use of formal health services in the Peruvian population: Analysis of the national household survey (Enaho) 2015

El objetivo del estudio fue estimar la prevalencia de la no utilización de los servicios formales de prestación de salud (NUSFPS) y sus factores asociados en Perú. Se realizó un análisis secundario de datos de la Encuesta Nacional de Hogares (ENAHO) del año 2015. Se definió como NUSFPS a aquellos participantes que, pese a haber presentado algún síntoma, malestar, enfermedad, recaída de enfermedad crónica o accidente durante el último mes, no acudieron a los servicios de salud. Se analizaron 35 036 participantes; la prevalencia de NUSFPS fue de 53,9% (IC95%:52,9-54,8). La NUSFPS fue superior en la costa (razón de prevalencia ajustada [RPa] = 1,24;IC95%:1,17-1,31), sierra (RPa = 1,38;IC95%:1,31-1,46) y selva (RP = 1,25;IC95%:1,18-1,33) en comparación a Lima Metropolitana. Hubo mayor prevalencia de NUSFPS en los participantes sin seguro (RPa = 1,59;IC95%:1,52-1,66) y afiliados al seguro integral de salud (RPa = 1,16;IC95%:1,11-1,22) comparados con los afiliados a la Seguridad Social. En conclusión, más de la mitad de los participantes padecieron NUSFPS, lo cual se asoció con condiciones geográficas y de aseguramiento. Se sugieren políticas públicas informadas en la evidencia para mejorar esta situación.The aim of the study was to estimate the prevalence of non-use of health services (NUHS) and its associated factors using the National Household Survey (ENAHO 2015). The participants were defined as NUHS if they have presented any symptoms, discomfort, illness, relapse of chronic illness or accident during the last month and did not go to the health services. 35036 participants were analyzed; the prevalence of NUHS was 53,9%. NUHS was higher in the coastal region (adjusted Prevalence Ratio [aPR]=1.24;95%CI:1.17-1.31), highlands (aPR=1.38;95%CI:1.31-1.46) and jungle (aPR=1.25,95%CI:1.18-1.33) compared to Lima. Likewise, there were a higher prevalence of NUHS in participants without health insurance (aPR=1.59;95%CI:1.52-1.66) and those affiliated to Ministry of Health insurance (aPR=1.16;95%CI:1.11-1.22) compared to those affiliated to Social Security. More than half of the participants suffered from NUHS, which was associated with geographical and health system conditions. It is required evidenced-informed public policies to improve this situation.Revisión por pare

Antibodies to endothelial cells in Behçet's disease: cell-binding heterogeneity and association with clinical activity

OBJECTIVES--To investigate the prevalence and characteristics of antibodies to endothelial cells (aEC) from large vessel and from microvasculature in a group of patients with Behçet's disease (BD) to determine the relationship of these antibodies with clinical and laboratory features of the disease. METHODS--Thirty patients with BD were prospectively and consecutively studied. The aEC were determined by enzyme-linked immunosorbent assay (ELISA) using endothelial cells derived from human umbilical vein (large vessel) as well as from retroperitoneal adipose tissue (microvasculature). RESULTS--Fifteen patients (50%) had aEC, either directed to large vessel [8(26%) patients] or microvascular [13(43%) patients] endothelial cells. The percentage of active patients was significantly higher in the aEC-positive group [12(80%) patients] compared with the aEC-negative group [5(33%) patients] (p < 0.05). CONCLUSIONS--Patients with BD have a high prevalence of aEC when microvascular endothelial cells are used in the assay. These antibodies seem to be a marker of disease activity in this condition, previously considered as negative for autoantibodies

CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

Identification of new markers associated with long-term efficacy in patients treated with CAR T cells is a current medical need, particularly in diseases such as multiple myeloma. In this study, we address the impact of CAR density on the functionality of BCMA CAR T cells. Functional and transcriptional studies demonstrate that CAR T cells with high expression of the CAR construct show an increased tonic signaling with up-regulation of exhaustion markers and increased in vitro cytotoxicity but a decrease in in vivo BM infiltration. Characterization of gene regulatory networks using scRNA-seq identified regulons associated to activation and exhaustion up-regulated in CARHigh T cells, providing mechanistic insights behind differential functionality of these cells. Last, we demonstrate that patients treated with CAR T cell products enriched in CARHigh T cells show a significantly worse clinical response in several hematological malignancies. In summary, our work demonstrates that CAR density plays an important role in CAR T activity with notable impact on clinical response