169 research outputs found

    El derecho real de hipoteca, la venta con pacto de retroventa y su relación con el contrato de mutuo o prestamo de consumo

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    La investigación que se realiza tiene como objetivo presentar un estudio documental sobre: El derecho real de hipoteca, la venta con pacto de retroventa y su relación con el contrato de mutuo o préstamo de consumo, se puede decir que es muy escaza la información del marco documental en lo que se refiere al pacto de retroventa con que cuentan las principales bibliotecas de nuestro país; por esta razón se pretende que este trabajo constituya una fuente de consulta para todos aquellos estudiosos del derecho interesados en el tema y verifiquen documental e empírica la temática que se aborda en esta investigación

    Complicaciones según manejo quirúrgico en pacientes con vólvulo de sigmoides en los Hospitales del Ministerio de Salud del Cusco 2015 - 2019

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    ANTECEDENTES: El vólvulo de sigmoides representa más del 50% de las obstrucciones intestinales, en el Perú la incidencia llega al 75%, es una emergencia frecuente y requiere un diagnóstico precoz y manejo oportuno, el estudio tiene como objetivo determinar si existe asociación entre el manejo quirúrgico y las complicaciones post operatorias en pacientes con vólvulo de sigmoides en los Hospitales del Ministerio de Salud Cusco en el periodo 2015 – 2019. METODO: El presente trabajo es de tipo cualitativo de corte transversal, retrospectivo y analítico. El diseño es observacional. Se revisaron 350 historias clínicas de pacientes atendidos en los hospitales del Ministerio de Salud del Cusco en el periodo del 2015 – 2019. Para el análisis estadístico se utilizó SPSS 21.0 y Microsoft Office Excel 2016. RESULTADOS: El vólvulo de sigmoides afecta más al género masculino (77.4%) con edades entre 60 y 69 años de procedencia rural (67.7%). Las complicaciones fueron más frecuentes en pacientes masculinos (26.2%) > 80 años (36%) de procedencia urbana (26.5%). El manejo quirúrgico más usado fue anastomosis primaria (76.8%) seguida por colostomía tipo Hartmann (22.6%). Las complicaciones se presentaron en el 41.8% (33/79) de colostomía Hartmann y 19.3% (52/269) de anastomosis primaria. Del total el 24.9% presentó complicaciones, las más frecuentes fueron: dehiscencia de anastomosis (11.6%) seguida de evisceración e infección de sitio operatorio (10.1%) cada una, el 46.5% son catalogadas como “otras”. La relación entre los parámetros pre, intra y postoperatorios frente a las complicaciones fueron significativos. La mortalidad fue del 6.6.%. CONCLUSIONES: Existe relación estadísticamente significativa entre el manejo quirúrgico y las complicaciones post operatorias en pacientes con vólvulo de sigmoides.BACKGROUND: Sigmoid volvulus accounts for more than 50% of intestinal obstructions, in Peru the incidence reaches 75%, it is a frequent emergency and requires early diagnosis and prompt management. The study aims to determine whether there is an association between surgical management and post-operative complications in patients with sigmoid volvulus in the Hospitals of the Ministry of Health in Cusco in the period 2015-2019. METHOD: This work is qualitative, cross-sectional, retrospective and analytical. The design is observational. 350 medical records of patients operated on for sigmoid volvulus who met the inclusion and exclusion criteria in the hospitals of the Ministry of Health of Cusco in the period of 2015-2019 were reviewed. For the statistical analysis, SPSS 21.0 and Microsoft Office Excel 2016. RESULTS: Sigmoid volvulus affects more males (77.4%) with ages between 60 and 69 years of rural origin (67.7%). Complications were more frequent in male patients (26.2%)> 80 years (36%) of urban origin (26.5%). The most widely used surgical management was primary anastomosis (76.8%) followed by a Hartmann-type colostomy (22.6%). Complications occurred in 41.8% (33/79) of Hartmann colostomy and 19.3% (52/269) of primary anastomosis. Of the total, 24.9% presented complications, the most frequent were: anastomosis dehiscence (11.6%) followed by evisceration and infection of the operative site (10.1%) each, 46.5% are classified as "other". The relationship between the pre, intra, and postoperative parameters versus complications were significant. Mortality was 6.6.% BACKGROUND: Sigmoid volvulus accounts for more than 50% of intestinal obstructions, in Peru the incidence reaches 75%, it is a frequent emergency and requires early diagnosis and prompt management. The study aims to determine whether there is an association between surgical management and post-operative complications in patients with sigmoid volvulus in the Hospitals of the Ministry of Health in Cusco in the period 2015-2019. METHOD: This work is qualitative, cross-sectional, retrospective and analytical. The design is observational. 350 medical records of patients operated on for sigmoid volvulus who met the inclusion and exclusion criteria in the hospitals of the Ministry of Health of Cusco in the period of 2015-2019 were reviewed. For the statistical analysis, SPSS 21.0 and Microsoft Office Excel 2016. RESULTS: Sigmoid volvulus affects more males (77.4%) with ages between 60 and 69 years of rural origin (67.7%). Complications were more frequent in male patients (26.2%)> 80 years (36%) of urban origin (26.5%). The most widely used surgical management was primary anastomosis (76.8%) followed by a Hartmann-type colostomy (22.6%). Complications occurred in 41.8% (33/79) of Hartmann colostomy and 19.3% (52/269) of primary anastomosis. Of the total, 24.9% presented complications, the most frequent were: anastomosis dehiscence (11.6%) followed by evisceration and infection of the operative site (10.1%) each, 46.5% are classified as "other". The relationship between the pre, intra, and postoperative parameters versus complications were significant. Mortality was 6.6.% BACKGROUND: Sigmoid volvulus accounts for more than 50% of intestinal obstructions, in Peru the incidence reaches 75%, it is a frequent emergency and requires early diagnosis and prompt management. The study aims to determine whether there is an association between surgical management and post-operative complications in patients with sigmoid volvulus in the Hospitals of the Ministry of Health in Cusco in the period 2015-2019. METHOD: This work is qualitative, cross-sectional, retrospective and analytical. The design is observational. 350 medical records of patients operated on for sigmoid volvulus who met the inclusion and exclusion criteria in the hospitals of the Ministry of Health of Cusco in the period of 2015-2019 were reviewed. For the statistical analysis, SPSS 21.0 and Microsoft Office Excel 2016. RESULTS: Sigmoid volvulus affects more males (77.4%) with ages between 60 and 69 years of rural origin (67.7%). Complications were more frequent in male patients (26.2%)> 80 years (36%) of urban origin (26.5%). The most widely used surgical management was primary anastomosis (76.8%) followed by a Hartmann-type colostomy (22.6%). Complications occurred in 41.8% (33/79) of Hartmann colostomy and 19.3% (52/269) of primary anastomosis. Of the total, 24.9% presented complications, the most frequent were: anastomosis dehiscence (11.6%) followed by evisceration and infection of the operative site (10.1%) each, 46.5% are classified as "other". The relationship between the pre, intra, and postoperative parameters versus complications were significant. Mortality was 6.6.% CONCLUSIONS: There is a statistically significant relationship between surgical management and postoperative complications in patients with sigmoid volvulus.Tesi

    Análisis comparativo de la reglamentación pertinente de centros educativos. Casos de estudio pabellón a (ingeniería) y pabellón o (industrial)

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    En el presente trabajo se tiene objetivo principal comparar las normas de arquitectura y ver el nivel de importancia en los pabellones de estudio. Para lograr este objetivo, la investigación se desarrolló mediante la lectura de reglamentos nacionales e internacionales, la normativa de MINEDU, libros y artículos del tema, luego se comparó y verificó las características particulares de cada pabellón, en el análisis de los resultados obtenidos de normas internacionales hay un consenso en bienestar de los alumnos con respecto al ambiente de estudio, también el cumplimiento del reglamento y normas del MINEDU en las infraestructuras. En el trabajo de investigación también se vio el tema de arquitectura bioclimática en centros educativos, donde se comprueba la influencia en el diseño de los pabellones

    Initial adherence of EPEC, EHEC and VTEC to host cells

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    Initial adherence to host cells is the first step of the infection of enteropathogenic Escherichia coli (EPEC), enterohaemorrhagic Escherichia coli (EHEC) and verotoxigenic Escherichia coli (VTEC) strains. The importance of this step in the infection resides in the fact that (1) adherence is the first contact between bacteria and intestinal cells without which the other steps cannot occur and (2) adherence is the basis of host specificity for a lot of pathogens. This review describes the initial adhesins of the EPEC, EHEC and VTEC strains. During the last few years, several new adhesins and putative colonisation factors have been described, especially in EHEC strains. Only a few adhesins (BfpA, AF/R1, AF/R2, Ral, F18 adhesins) appear to be host and pathotype specific. The others are found in more than one species and/or pathotype (EPEC, EHEC, VTEC). Initial adherence of EPEC, EHEC and VTEC strains to host cells is probably mediated by multiple mechanisms

    "The contribution of chronic diseases to the prevalence of dependence among older people in Latin America, China and India: a 10/66 Dementia Research Group population-based survey"

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    <p>Abstract</p> <p>Background</p> <p>The number of older people is set to increase dramatically worldwide. Demographic changes are likely to result in the rise of age-related chronic diseases which largely contribute to years lived with a disability and future dependence. However dependence is much less studied although intrinsically linked to disability. We investigated the prevalence and correlates of dependence among older people from middle income countries.</p> <p>Methods</p> <p>A one-phase cross-sectional survey was carried out at 11 sites in seven countries (urban sites in Cuba, Venezuela, and Dominican Republic, urban and rural sites in Peru, Mexico, China and India). All those aged 65 years and over living in geographically defined catchment areas were eligible. In all, 15,022 interviews were completed with an informant interview for each participant. The full 10/66 Dementia Research Group survey protocol was applied, including ascertainment of depression, dementia, physical impairments and self-reported diagnoses. Dependence was interviewer-rated based on a key informant's responses to a set of open-ended questions on the participant's needs for care. We estimated the prevalence of dependence and the independent contribution of underlying health conditions. Site-specific prevalence ratios were meta-analysed, and population attributable prevalence fractions (PAPF) calculated.</p> <p>Results</p> <p>The prevalence of dependence increased with age at all sites, with a tendency for the prevalence to be lower in men than in women. Age-standardised prevalence was lower in all sites than in the USA. Other than in rural China, dementia made the largest independent contribution to dependence, with a median PAPF of 34% (range 23%-59%). Other substantial contributors were limb impairment (9%, 1%-46%), stroke (8%, 2%-17%), and depression (8%, 1%-27%).</p> <p>Conclusion</p> <p>The demographic and health transitions will lead to large and rapid increases in the numbers of dependent older people particularly in middle income countries (MIC). The prevention and control of chronic neurological and neuropsychiatric diseases and the development of long-term care policies and plans should be urgent priorities.</p

    A long-period transiting substellar companion in the super-Jupiters to brown dwarfs mass regime and a prototypical warm-Jupiter detected by TESS

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    We report on the confirmation and follow-up characterization of two long-period transiting substellar companions on low-eccentricity orbits around TIC 4672985 and TOI-2529, whose transit events were detected by the TESS space mission. Ground-based photometric and spectroscopic follow-up from different facilities, confirmed the substellar nature of TIC 4672985 b, a massive gas giant, in the transition between the super Jupiters and brown dwarfs mass regime. From the joint analysis we derived the following orbital parameters: P = 69.0480 d, Mp = 12.74 Mjup, Rp = 1.026 Rjup and e = 0.018. In addition, the RV time series revealed a significant trend at the 350 m/s/yr level, which is indicative of the presence of a massive outer companion in the system. TIC 4672985 b is a unique example of a transiting substellar companion with a mass above the deuterium-burning limit, located beyond 0.1 AU and in a nearly circular orbit. These planetary properties are difficult to reproduce from canonical planet formation and evolution models. For TOI-2529 b, we obtained the following orbital parameters: P = 64.5949 d, Mp = 2.340 Mjup, Rp = 1.030 Rjup and e = 0.021, making this object a new example of a growing population of transiting warm giant planets.Comment: Accepted in A&

    Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative

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