Do board gender quotas affect how people perceive firms? A study of the California board gender quota law with Twitter sentiment data

The first compulsory board gender diversity quota law in the United States was approved in 2018 in California. In this study, we aim to analyse how public perception has been influenced by the application of this gender quota law, using Twitter Sentiment Score of public companies affected by it. Specifically, the whole Twitter history between 2016-2021 of approximately 200 firms has been scrapped and the daily, monthly and yearly sentiment score has been computed. Moreover, the gender of the account associated with the tweet has been analysed in order to test differences between male and female sentiment. The results show that there is a positive effect of the increase in share of women in the board on the percentage of positive tweets. Moreover, the effects of the pool of tweets of women and men are opposite, positive for women and negative for men. Finally, the effect of the California gender quota law on Twitter sentiment has been studied. Those companies with a lower share of women(do not comply with the law after it was passed) experienced a higher increase in share of positive tweets in the post law period compared with the companies that were already complying with the lawObjectius de Desenvolupament Sostenible::10 - Reducció de les Desigualtats::10.3 - Garantir la igualtat d’oportunitats i reduir la desigualtat dels resultats, també eli­minant les lleis, polítiques i pràctiques discriminatòries i promovent legislació, polítiques i mesures adequades a aquest efect

Comparison of different Internet of Things platforms

Aquest projecte s’emmarca en el concepte de la IoT (la Internet de les coses) i té com a objectiu dur a terme el desplegament d’una arquitectura IoT utilitzant un dispositiu amb connectivitat Sigfox i diferents plataformes IoT com AWS IBM Watson IoT, Microsoft Azure i thethings.iO. El dispositiu Sigfox està transmetent mesures de temperatura i aquestes s’envien a les plataformes IoT, que han estat configurades per rebre i emmagatzemar les dades. Un cop les dades s’han emmagatzemat a les plataformes, l’objectiu principal és poder analitzar-les i treure’n informació valuosa. Per tant, s’han dut a terme visualitzacions gràfiques. Després de desplegar les diferents arquitectures IoT, les plataformes han estat testejades per verificar les diferències entre elles pel que fa al processament de dades i a la visualització. S’han comparat considerant característiques com facilitat de connectar els dispositius i analitzar les dades, preu, flexibilitat o serveis. Aquesta memòria explicarà com configurar aquestes plataformes per poder rebre i analitzar les dades, utilitzant l’exemple del sensor de temperatura, i quina d’elles és més adequada per resoldre una necessitat concreta d’algun camp del coneixement

Neuroprotective Actions of Estradiol and Novel Estrogen Analogs in Ischemia: Translational Implications

This review highlights our investigations into the neuroprotective efficacy of estradiol and other estrogenic agents in a clinically relevant animal model of transient global ischemia, which causes selective, delayed death of hippocampal CA1 neurons and associated cognitive deficits. We find that estradiol rescues a significant number of CA1 pyramidal neurons that would otherwise die in response to global ischemia, and this is true when hormone is provided as a long-term pretreatment at physiological doses or as an acute treatment at the time of reperfusion. In addition to enhancing neuronal survival, both forms of estradiol treatment induce measurable cognitive benefit in young animals. Moreover, estradiol and estrogen analogs that do not bind classical nuclear estrogen receptors retain their neuroprotective efficacy in middle-aged females deprived of ovarian hormones for a prolonged duration (8 weeks). Thus, non-feminizing estrogens may represent a new therapeutic approach for treating the neuronal damage associated with global ischemia

Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

Association of a single nucleotide polymorphism combination pattern of the Klotho gene with non-cardiovascular death in patients with chronic kidney disease

Chronic kidney disease (CKD) is associated with an elevated risk of all-cause mortality, with cardiovascular death being extensively investigated. However, non-cardiovascular mortality represents the biggest percentage, showing an evident increase in recent years. Klotho is a gene highly expressed in the kidney, with a clear influence on lifespan. Low levels of Klotho have been linked to CKD progression and adverse outcomes. Single nucleotide polymorphisms (SNPs) of the Klotho gene have been associated with several diseases, but studies investigating the association of Klotho SNPs with noncardiovascular death in CKD populations are lacking. The main aim of this study was to assess whether 11 Klotho SNPs were associated with non-cardiovascular death in a subpopulation of the National Observatory of Atherosclerosis in Nephrology (NEFRONA) study (n ¼ 2185 CKD patients). After 48 months of follow-up, 62 cardiovascular deaths and 108 non-cardiovascular deaths were recorded. We identified a high non-cardiovascular death risk combination of SNPs corresponding to individuals carrying the most frequent allele (G) at rs562020, the rare allele (C) at rs2283368 and homozygotes for the rare allele (G) at rs2320762 (rs562020 GG/AG þ rs2283368 CC/CT þ rs2320762 GG). Among the patients with the three SNPs genotyped (n ¼ 1016), 75 (7.4%) showed this combination. Furthermore, 95 (9.3%) patients showed a low-risk combination carrying all the opposite genotypes (rs562020 AA þ rs2283368 TT þ rs2320762 GT/TT). All the other combinations [n ¼ 846 (83.3%)] were considered as normal risk. Using competing risk regression analysis, we confirmed that the proposed combinations are independently associated with a higher fhazard ratio [HR] 3.28 [confidence interval (CI) 1.51-7.12]g and lower [HR 6 × 10- (95% CI 3.3 × 10--1.1 × 10-)] risk of suffering a non-cardiovascular death in the CKD population of the NEFRONA cohort compared with patients with the normal-risk combination. Determination of three SNPs of the Klotho gene could help in the prediction of non-cardiovascular death in CKD

Association of candidate gene polymorphisms with chronic kidney disease : Results of a case-control analysis in the NEFRONA cohort

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2,445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionization-time of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

TFG 2015/2016

Amb aquesta publicació, EINA, Centre universitari de Disseny i Art adscrit a la Universitat Autònoma de Barcelona, dóna a conèixer el recull dels Treballs de Fi de Grau presentats durant el curs 2015-2016. Voldríem que un recull com aquest donés una idea més precisa de la tasca que es realitza a EINA per tal de formar nous dissenyadors amb capacitat de respondre professionalment i intel·lectualment a les necessitats i exigències de la nostra societat. El treball formatiu s’orienta a oferir resultats que responguin tant a paràmetres de rigor acadèmic i capacitat d’anàlisi del context com a l’experimentació i la creació de nous llenguatges, tot fomentant el potencial innovador del disseny.Con esta publicación, EINA, Centro universitario de diseño y arte adscrito a la Universidad Autónoma de Barcelona, da a conocer la recopilación de los Trabajos de Fin de Grado presentados durante el curso 2015-2016. Querríamos que una recopilación como ésta diera una idea más precisa del trabajo que se realiza en EINA para formar nuevos diseñadores con capacidad de responder profesional e intelectualmente a las necesidades y exigencias de nuestra sociedad. El trabajo formativo se orienta a ofrecer resultados que respondan tanto a parámetros de rigor académico y capacidad de análisis, como a la experimentación y la creación de nuevos lenguajes, al tiempo que se fomenta el potencial innovador del diseño.With this publication, EINA, University School of Design and Art, affiliated to the Autonomous University of Barcelona, brings to the public eye the Final Degree Projects presented during the 2015-2016 academic year. Our hope is that this volume might offer a more precise idea of the task performed by EINA in training new designers, able to speak both professionally and intellectually to the needs and demands of our society. The educational task is oriented towards results that might respond to the parameters of academic rigour and the capacity for contextual analysis, as well as to considerations of experimentation and the creation of new languages, all the while reinforcing design’s innovative potential

Comparison of different Internet of Things platforms

Aquest projecte s’emmarca en el concepte de la IoT (la Internet de les coses) i té com a objectiu dur a terme el desplegament d’una arquitectura IoT utilitzant un dispositiu amb connectivitat Sigfox i diferents plataformes IoT com AWS IBM Watson IoT, Microsoft Azure i thethings.iO. El dispositiu Sigfox està transmetent mesures de temperatura i aquestes s’envien a les plataformes IoT, que han estat configurades per rebre i emmagatzemar les dades. Un cop les dades s’han emmagatzemat a les plataformes, l’objectiu principal és poder analitzar-les i treure’n informació valuosa. Per tant, s’han dut a terme visualitzacions gràfiques. Després de desplegar les diferents arquitectures IoT, les plataformes han estat testejades per verificar les diferències entre elles pel que fa al processament de dades i a la visualització. S’han comparat considerant característiques com facilitat de connectar els dispositius i analitzar les dades, preu, flexibilitat o serveis. Aquesta memòria explicarà com configurar aquestes plataformes per poder rebre i analitzar les dades, utilitzant l’exemple del sensor de temperatura, i quina d’elles és més adequada per resoldre una necessitat concreta d’algun camp del coneixement

Comparison of different Internet of Things platforms

Aquest projecte s’emmarca en el concepte de la IoT (la Internet de les coses) i té com a objectiu dur a terme el desplegament d’una arquitectura IoT utilitzant un dispositiu amb connectivitat Sigfox i diferents plataformes IoT com AWS IBM Watson IoT, Microsoft Azure i thethings.iO. El dispositiu Sigfox està transmetent mesures de temperatura i aquestes s’envien a les plataformes IoT, que han estat configurades per rebre i emmagatzemar les dades. Un cop les dades s’han emmagatzemat a les plataformes, l’objectiu principal és poder analitzar-les i treure’n informació valuosa. Per tant, s’han dut a terme visualitzacions gràfiques. Després de desplegar les diferents arquitectures IoT, les plataformes han estat testejades per verificar les diferències entre elles pel que fa al processament de dades i a la visualització. S’han comparat considerant característiques com facilitat de connectar els dispositius i analitzar les dades, preu, flexibilitat o serveis. Aquesta memòria explicarà com configurar aquestes plataformes per poder rebre i analitzar les dades, utilitzant l’exemple del sensor de temperatura, i quina d’elles és més adequada per resoldre una necessitat concreta d’algun camp del coneixement