Variation of the partition coefficient of phase-partitioning compounds between hydrocarbon and aqueous phases: an experimental study.

Many non-ionic chemical compounds will form real solutions in equilibrium between two immiscible phases in contact. The partition coefficient (K) is defined as the quotient between the equilibrium concentration of the substance in the hydrocarbon and the aqueous phase. The reversible partition of a compound between hydrocarbon and aqueous phases is the basis of the partitioning inter-well tracer test (PITT). PITTs are of high interest for the characterization of oil reservoirs, in hydrogeology for assessment of the contamination of soils by non-aqueous phase liquids (NAPLs), and in process technology. The K value of substance is influenced by the actual chemical and physical conditions of the system where it will be used as phase-partitioning tracer. Thus, it is important to evaluate the extent of variation that the K value can exhibit under different relevant conditions. In the present document, we report the methodology and findings from the experimental determination of the K values of 4-methoxybenzyl alcohol, 3,4-dimethoxybenzyl alcohol, 4-chlorobenzyl alcohol, 2,6-dichlorobenzyl alcohol, pyridine, 2,3-dimethylpyrazine and 2,6-dimethylpyrazine between different hydrocarbon and aqueous phases. These 7 compounds were previously identified as interesting PITT tracer candidates. Individual K-values were determined under different temperatures, compositions of the hydrocarbon phase (synthetic mixtures of toluene, isooctane, and 1-octanol and 5 real crude oils), and different ionic strengths (I) and ionic compositions of the aqueous phase. The reversibility of the partitioning phenomena was also evaluated. The composition of the hydrocarbon phase and the ionic strength of the water phase were found to influence the K values of all seven compounds. Results suggest that the substitution of monovalent ions with divalent ions in the aqueous phase, keeping the ionic strength constant, does not influence the K values. Temperature effects on the K-values are always visible for 3,4-dimethoxybenzyl alcohol, 2,6-dichlorobenzyl alcohol, pyridine, 2,3-dimethylpyrazine and 2,6-dimethylpyrazine. Dependent on the hydrocarbon phase composition, temperature also influences the K-values for 4-methoxybenzyl alcohol and 4-chlorobenzyl alcohol.publishedVersio

Thermal stability and interactions with sedimentary rocks under typical reservoir conditions of selected pyridines investigated as phase partitioning tracers

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A young man with acute dilated cardiomyopathy associated with methylphenidate

An 18-year-old obese man with a body mass index of 40, diagnosed with attention-deficit hyperactivity disorder and treated with methylphenidate (Concerta®) was acutely admitted to hospital with hypoxia and dyspnoea. On investigation signs of liver-, renal-, and heart-failure were found. Noradrenalin infusion was started. Echocardiography showed dilated left ventricle and an ejection fraction (EF) of 25%. Liver function improved, noradrenalin and dobutamine were tapered, but three days after admission a new echocardiography showed an EF of 10%. The patient was transferred to the National Hospital (Rikshospitalet, Oslo), where intensified treatment including intra aortic balloon pump (IABP) was instituted. Cardiac function improved, and 3 weeks later the IABP was disconnected. EF at this point was 15%. The patient was denied heart transplantation due to various cofactors. The investigation concluded with a probable relationship between his cardiomyopathy and the use of methylphenidate (Concerta)

Measurement of ϒ production in pp collisions at √s = 2.76 TeV

The production of ϒ(1S), ϒ(2S) and ϒ(3S) mesons decaying into the dimuon final state is studied with the LHCb detector using a data sample corresponding to an integrated luminosity of 3.3 pb−1 collected in proton–proton collisions at a centre-of-mass energy of √s = 2.76 TeV. The differential production cross-sections times dimuon branching fractions are measured as functions of the ϒ transverse momentum and rapidity, over the ranges pT < 15 GeV/c and 2.0 < y < 4.5. The total cross-sections in this kinematic region, assuming unpolarised production, are measured to be σ (pp → ϒ(1S)X) × B ϒ(1S)→μ+μ− = 1.111 ± 0.043 ± 0.044 nb, σ (pp → ϒ(2S)X) × B ϒ(2S)→μ+μ− = 0.264 ± 0.023 ± 0.011 nb, σ (pp → ϒ(3S)X) × B ϒ(3S)→μ+μ− = 0.159 ± 0.020 ± 0.007 nb, where the first uncertainty is statistical and the second systematic

Applicability and sensitivity of gamma transmission and radiotracer techniques for mineral scaling studies

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Determination of phase-partitioning tracer candidates in production waters from oilfields based on solid-phase microextraction followed by gas chromatography-tandem mass spectrometry

In the present document, we report the development of an analytical method consisting of a sequential direct-immersion/headspace solid-phase microextraction (DI-HS-SPME) followed by gas-phase chromatography and tandem mass spectrometry (GC-MS/MS) for simultaneous analysis of 4-chlorobenzyl alcohol, 2,6-dichlorobenzyl alcohol, 4-methoxybenzyl alcohol, 3,4-dimethoxybenzyl alcohol, pyridine, and 2,3-dimethylpyrazine in oilfield production waters. These compounds are under evaluation for use as phase-partitioning tracers in oil reservoirs. To the best of our knowledge, this is the first time SPME has been applied to the analysis of these compounds in production waters, or any other type of matrix where the compounds targeted are the base for a technical application. Relevant extraction parameters, such as the adsorbent phase of the fiber, direct immersion or headspace, addition of salt, temperature and time of extraction were investigated. The final optimal operation conditions consist on extracting 5 mL of sample at pH 9.0 with 1.8 g of NaCl with constant stirring during 5 minutes of DI-SPME followed by 15 minutes of HS-SPME at 70 °C using a DVB/CAR/PDMS (50/30 µm) fiber. The limits of quantification (LOQ), linearity, precision and accuracy of the method were evaluated. Analyses of the tracer compounds and recovery studies were also performed on production waters from 8 different oilfields of the Norwegian continental shelf. LOQs between 0.080 and 0.35 µg L−1 were obtained. The recovery yields of the method were consistently higher than 85% and RSDs less than 13%. None of the tracer compounds was found in the real samples processed, which is consistent with one of the requirements for an artificial tracer in an oilfield: absence or constant and low background in the traced fluid. The performance of the method developed, combined with its easiness to automate, introduce a new, accurate and cost-efficient technique to process the hundreds of samples required by an inter-well tracer test.publishedVersio

Stability assessment of PITT tracer candidate compounds: the case of benzyl alcohols

The selection of compounds used as inter-well tracers has traditionally been done taking into consideration the goal of the test and the ease in analyzing the chemicals used. This often led to improper selection of the tracers and insufficient knowledge about their behavior under typical reservoir conditions, resulting in several unsuccessful inter-well tracer tests. One of the critical characteristics of any conservative tracer is its stability under various reservoir conditions. In this document we present the study methodology and the findings from stability experiments carried out on 5 benzyl alcohols investigated as oil/water partitioning tracers for partitioning inter-well tracer tests (PITT). This is the first of three documents reporting such studies on 3 families of chemicals. A PITT consists of the simultaneous injection of one or more mass-conservative passive and phase-partitioning (one type of active) tracers. PITT is primarily conceived for mature water-flooded oil fields and measures the residual (or even remaining) oil saturation (SOR) in the swept volumes between wells. Knowledge of SOR may be used to identify EOR targets, assess efficiency of EOR operations, and the efficiency of volumetric sweep between wells. This is important information, in particular for the increasing number of mature oil-fields where EOR projects are under consideration and/or development. A thorough knowledge about the static and dynamic properties of the tracers under reservoir conditions is required both to ensure successful field tests, and also to increase accuracy of the data obtained from them. 4-Chlorobenzyl alcohol, 2,6-Dichlorobenzyl alcohol, 4-Methoxybenzyl alcohol, 3,4-Dimethoxybenzyl alcohol, and 4-Hydroxybenzyl alcohol were tested in brine under simulated reservoir conditions with temperatures up to 150 °C during 12 weeks, at different pH values, and in the presence of typical sedimentary basin rock materials, sandstone, carbonate rock (limestone), and clay (kaolinite). 4-Chlorobenzyl alcohol and 2,6-Dichlorobenzyl alcohol were found to be fully stable at all tested conditions. 4-Methoxybenzyl alcohol and 3,4-Dimethoxybenzyl alcohol exhibit thermally induced degradation above 125 °C, but may still be considered for use below this temperature. 4-Hydroxybenzyl alcohol exhibits thermally induced degradation which was found to follow a first order kinetics. The apparent activation energy and pre-exponential constant in the Arrhenius law for the degradation reaction were determined and a kinetic model built. This opens the possibility for use of 4-Hydroxybenzyl alcohol as a non-conservative reservoir tracer to measure temperature or detect thermal fronts.acceptedVersio

Exploring laser induced Single Event Latch-up in AMS 0.35um

This thesis explores different Single Event Latch-up (SEL) hardness techniques against radiation in a commercial 0.35µm technology from AMS. Techniques like increasing nMOS to pMOS distance, guard rings, source to N-well/P-substrate contact distance, increasing N-well size, source/drain diffusion area, transistor width as well as relative transistor orientation are investigated and tested to achieve a high SEL threshold. Several structures holding these techniques are made in two different options of AMS 0.35µm, one option with bulk (C35B4C3) and the other with an exitaxial layer (C35B4O1) in order to investigate the differences. The structures are based on the inverter in order to make the test structures as close to actual circuit design as possible. The inverter is also a favorable structure because it represents a worst case latch-up situation because of the parasitic components arising and the simple model needed to characterize it. The thesis also investigates whether using a pulsed laser module is suitable to investigate SEL susceptibility in favor of a particle accelerator. The structures were exposed to infrared (1064nm) laser pulses in order to emulate high energy particles striking the ASIC. The use of laser beam with a spot size of 2µm*2µm opened the possibility to choose which structure to expose with minimum impact on the nearby structures. By increasing the energy of the laser pulses, the SEL threshold of each structure could be determined by empirical testing. A digital input signal is propagated trough the structures in order to confirm which structure experiences latch-up. A set of switches on the PCB is used to choose which structure to monitor. The current usage of the ASIC is monitored in order to detect latch-up and to log the latch-up current. Measurements presented a “threshold” distance between the contact and source of the transistors. If the contact-source distance is increased beyond 4.5µm the SEL threshold decreased about 70% in the epitaxial device. In the bulk device, if the contact-source distance was increased beyond 2.0µm the SEL threshold decreased to a level 12% beneath the reference structure. The most effective structure in the epitaxial device was the structure with the N-well/P-substrate contacts placed in between the transistors. This structure presented a 30% decreased area and 87% higher threshold than the structure with the lowest threshold. Though, only 2.5% higher threshold than second place and the same area. The most effective structure in the bulk device was the structure with nMOS source to pMOS source distance of 7.4 µm and the minimum N-well/P-substrate contact to source distance of 0.6µm. This structure presented a 17% decreased area, a 465% higher SEL threshold and a 30% higher SEL current in comparison to the reference structure

Applicability and sensitivity of gamma transmission and radiotracer techniques for mineral scaling studies

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