14 research outputs found
Anticancer activity of vitamin E-derived compounds in murine C6 glioma cells.
Get PDFnone7A small library of vitamin E analogues, with a free acid group linked to the chroman core through an amide, ether or ester bond, was synthesized and evaluated for their anticancer potency on C6 murine glioma cells. Several compounds showed antitumor activity better than temozolomide, the mostly commonly used drug in the treatment of gliomas.openMazzini, F; Betti, Michele; Canonico, Barbara; Netscher, T; Luchetti, Francesca; Papa, Stefano; Galli, F.Mazzini, F; Betti, Michele; Canonico, Barbara; Netscher, T; Luchetti, Francesca; Papa, Stefano; Galli, F
Mitochondrial-dependent anticancer activity of δ-tocotrienol and its synthetic derivatives in HER-2/neu overexpressing breast adenocarcinoma cells
No full textAffinity of vitamin E analogues for the ubiquinone complex II site correlates with their toxicity to cancer cells
No full textQSAR studies and design of new analogs of vitamin E with enhanced antiproliferative activity on MCF-7 breast cancer cells
No full textTocopheramine succinate and tocopheryl succinate: Mechanism of mitochondrial inhibition and superoxide radical production
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Vitamin E analogues as anticancer agents: Lessons from studies with α-tocopheryl succinate
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