Osteoporose na pós-menopausa e a utilização de bisfosfonatos como opção terapêutica

Uma doença como característica de fragilidade óssea como a Osteoporose que afeta mais de 200 milhões de pessoas ao redor de todo o mundo, tem como principal característica ocorrência de fraturas de baixo impacto. Os pacientes que sobrevivem uma fratura de quadril tornam-se incapazes de manter uma vida independente, onde grande maioria necessita de um ambiente adequado. Num contexto geral esta doença não se apresenta com características clínicas especificas até o momento de uma primeira fratura. É uma patologia que acontece de forma crescente em termos de saúde em ambos os sexos, podendo ser dividida entre primária e secundária. A DMO tem seu pico atingido na idade adulta, mantendo-se constante em ambos os sexos até a idade de aproximadamente 40 anos, onde inicia sua redução espontânea após esta idade. Epidemiologicamente as fraturas vertebrais não são comparadas as fraturas de anca, por existir uma lacuna nos critérios de definição destas fraturas vertebrais. Um nutriente de bastante importância para regulação do tecido ósseo é o cálcio, onde sua ingesta é de extrema importância no tratamento de prevenção de osteoporose, assim como para a saúde óssea em qualquer idade, mesmo que suas necessidades diárias variem de idade para idade. Os bisfosfonatos são compostos sintéticos e possuem alta afinidade com cristais de cálcio no esqueleto, este confere maior resistência em sua degradação biológica. Os bisfosfonatos bloqueiam a quebra de síntese do farnesilpirofosfato e impede a isoprenilasão da guanosina trifosfato, que garante a integridade do citoesqueleto, sua absorção é limitada, tratando-se de uma absorção paracelular

SÍNDROME DOS OVÁRIOS POLICÍSTICOS (SOP): UMA ABORDAGEM ABRANGENTE

Polycystic Ovary Syndrome (PCOS) is a complex endocrine condition that affects women of reproductive age. It is characterized by hormonal imbalances, manifested by chronic anovulation, hyperandrogenism, and the presence of cysts on the ovaries. Diagnosis is established through clinical, laboratory, and ultrasound criteria. PCOS is associated with insulin resistance and often coexists with obesity. This condition can lead to metabolic complications such as type 2 diabetes and cardiovascular diseases. In addition to physical impacts, PCOS can have psychological repercussions, including issues related to self-image and social stigma. The treatment of PCOS encompasses pharmacological approaches, lifestyle modifications, and, in specific cases, surgical procedures. The importance of a multidisciplinary team, involving gynecologists, endocrinologists, nutritionists, and psychologists, stands out in the comprehensive management of the syndrome. Therapeutic strategies aim not only at hormonal regulation and restoration of fertility but also at improving the overall quality of life for the patient.A Síndrome dos Ovários Policísticos (SOP) é uma condição endócrina complexa que afeta mulheres em idade reprodutiva. Caracteriza-se por desequilíbrios hormonais, manifestados por anovulação crônica, hiperandrogenismo e a presença de cistos nos ovários. O diagnóstico é estabelecido por critérios clínicos, laboratoriais e ultrassonográficos. A SOP está associada à resistência à insulina e frequentemente coexiste com a obesidade. Essa condição pode resultar em complicações metabólicas, como diabetes tipo 2 e doenças cardiovasculares. Além dos impactos físicos, a SOP pode ter repercussões psicológicas, incluindo questões relacionadas à autoimagem e estigma social. O tratamento da SOP abrange abordagens farmacológicas, estilo de vida e, em casos específicos, procedimentos cirúrgicos. A importância de uma equipe multidisciplinar, envolvendo ginecologistas, endocrinologistas, nutricionistas e psicólogos, destaca-se na gestão integral da síndrome. Estratégias terapêuticas visam não apenas à regularização hormonal e restauração da fertilidade, mas também à melhoria da qualidade de vida global da paciente

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

ATLANTIC EPIPHYTES: a data set of vascular and non-vascular epiphyte plants and lichens from the Atlantic Forest

Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts. Our work presents the first epiphyte data set with information on abundance and occurrence of epiphyte phorophyte species. All data compiled here come from three main sources provided by the authors: published sources (comprising peer-reviewed articles, books, and theses), unpublished data, and herbarium data. We compiled a data set composed of 2,095 species, from 89,270 holo/hemiepiphyte records, in the Atlantic Forest of Brazil, Argentina, Paraguay, and Uruguay, recorded from 1824 to early 2018. Most of the records were from qualitative data (occurrence only, 88%), well distributed throughout the Atlantic Forest. For quantitative records, the most common sampling method was individual trees (71%), followed by plot sampling (19%), and transect sampling (10%). Angiosperms (81%) were the most frequently registered group, and Bromeliaceae and Orchidaceae were the families with the greatest number of records (27,272 and 21,945, respectively). Ferns and Lycophytes presented fewer records than Angiosperms, and Polypodiaceae were the most recorded family, and more concentrated in the Southern and Southeastern regions. Data on non-vascular plants and lichens were scarce, with a few disjunct records concentrated in the Northeastern region of the Atlantic Forest. For all non-vascular plant records, Lejeuneaceae, a family of liverworts, was the most recorded family. We hope that our effort to organize scattered epiphyte data help advance the knowledge of epiphyte ecology, as well as our understanding of macroecological and biogeographical patterns in the Atlantic Forest. No copyright restrictions are associated with the data set. Please cite this Ecology Data Paper if the data are used in publication and teaching events. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ

Forme d'organisation et profil environnemental de l'exploitation agricole : le cas du secteur laitier

This thesis contributes to the analysis of the relationship between farm’s forms of organization and environmental performance. The links between the way in which farm is organized and governed and all the practices related with its environmental profile will be studied. First, the economic literature about environmental performance of farms and its determinants will be reviewed. Based on the insights of the neo-institutional and the evolutionary economics, an analytical framework of the relationship between forms of organization and environmental profiles will be proposed. This framework will then be applied to dairy farms in three complementary chapters. These chapters combine both quantitative approach using data from the French agricultural census of 2010 and a qualitative approach from semi-directive interviews carried out in Brazil. An insight to the empirical literature on environmental performance will be provided thanks to a systemic and multi-criteria approach of dairy farms thought a profile of agro-environmental practices. The analysis of the determinants also shows the importance of studying the farm as complex system with its own structure, governance and adaptability evolving in its external environment. Finally, the thesis bring out that there is no strict alignment between forms of organization and environmental performance. However, certain forms are more apt than others to take into account certain agro-environmental practices.Cette thèse a pour objectif d’apporter une contribution à l’analyse de la relation entre formes d’organisation et performance environnementale des exploitations agricoles. Elle étudie les liens entre d’une part, la manière dont l’exploitation est organisée et gouvernée et, d’autre part, l’ensemble des pratiques qui fondent son profil environnemental. Elle offre une revue de la littérature économique relative à l’analyse de la performance environnementale des exploitations agricoles et de ses déterminants. Dans le prolongement des propositions théoriques relevant de l’économie néo-institutionnelle et de l’économie évolutionniste, elle propose un cadre analytique de la relation entre formes d’exploitation et profils environnementaux. Ce cadre est appliqué au cas des exploitations agricoles laitières autour de trois chapitres complémentaires, qui combinent à la fois une approche quantitative mobilisant des données du Recensement agricole français de 2010, et une approche qualitative basée sur des monographies d’exploitations réalisées au Brésil. Ainsi, cette thèse contribue à la littérature empirique sur la performance environnementale par son approche systémique et multicritère des exploitations laitières qui permet la construction d’un profil de pratiques agro-environnementales. Dans l’analyse des déterminants de ce profil, elle montre l’importance d’une conception de l’exploitation en tant que système complexe doté d’une structure, d’une gouvernance et d’une capacité d’adaptation propres, et évoluant en interaction avec son environnement externe. La thèse montre enfin qu’il n’existe pas un alignement strict entre formes d’organisation et performance environnementale mais que certaines formes d’exploitation sont plus aptes que d’autres à prendre en compte certaines pratiques agro-environnementales

Form of organization and environmental profile of the farm : the case of the dairy sector

Cette thèse a pour objectif d’apporter une contribution à l’analyse de la relation entre formes d’organisation et performance environnementale des exploitations agricoles. Elle étudie les liens entre d’une part, la manière dont l’exploitation est organisée et gouvernée et, d’autre part, l’ensemble des pratiques qui fondent son profil environnemental. Elle offre une revue de la littérature économique relative à l’analyse de la performance environnementale des exploitations agricoles et de ses déterminants. Dans le prolongement des propositions théoriques relevant de l’économie néo-institutionnelle et de l’économie évolutionniste, elle propose un cadre analytique de la relation entre formes d’exploitation et profils environnementaux. Ce cadre est appliqué au cas des exploitations agricoles laitières autour de trois chapitres complémentaires, qui combinent à la fois une approche quantitative mobilisant des données du Recensement agricole français de 2010, et une approche qualitative basée sur des monographies d’exploitations réalisées au Brésil. Ainsi, cette thèse contribue à la littérature empirique sur la performance environnementale par son approche systémique et multicritère des exploitations laitières qui permet la construction d’un profil de pratiques agro-environnementales. Dans l’analyse des déterminants de ce profil, elle montre l’importance d’une conception de l’exploitation en tant que système complexe doté d’une structure, d’une gouvernance et d’une capacité d’adaptation propres, et évoluant en interaction avec son environnement externe. La thèse montre enfin qu’il n’existe pas un alignement strict entre formes d’organisation et performance environnementale mais que certaines formes d’exploitation sont plus aptes que d’autres à prendre en compte certaines pratiques agro-environnementales.This thesis contributes to the analysis of the relationship between farm’s forms of organization and environmental performance. The links between the way in which farm is organized and governed and all the practices related with its environmental profile will be studied. First, the economic literature about environmental performance of farms and its determinants will be reviewed. Based on the insights of the neo-institutional and the evolutionary economics, an analytical framework of the relationship between forms of organization and environmental profiles will be proposed. This framework will then be applied to dairy farms in three complementary chapters. These chapters combine both quantitative approach using data from the French agricultural census of 2010 and a qualitative approach from semi-directive interviews carried out in Brazil. An insight to the empirical literature on environmental performance will be provided thanks to a systemic and multi-criteria approach of dairy farms thought a profile of agro-environmental practices. The analysis of the determinants also shows the importance of studying the farm as complex system with its own structure, governance and adaptability evolving in its external environment. Finally, the thesis bring out that there is no strict alignment between forms of organization and environmental performance. However, certain forms are more apt than others to take into account certain agro-environmental practices

Farms’ environmental impact and economic performance: the case of an Amazonian beef farm

This work studies the environmental impacts and economic performances of an Amazonian traditional beef farm, using a production cost and profitability analysis (Matsunaga et al., 1976) and a Life Cycle Assessment Standards Model (ISO 14044, 2006). The results reveal that economic and environmental performances share the same kind of determinants – low productivity of animals and land – which are major problems in Brazilian extensive livestock farms. Better management practices and technical efficiency associated with an “ecological intensification” of the production system could be a “win-win” strategy (Porter, 1991; Porter and van der Linde, 1995) in order to improve both performances

Organizational Forms and Agri-Environmental Practices: The Case of Brazilian Dairy Farms

Understanding the relationship between the organizational characteristics of a farm and its environmental performance is essential to support the agro-ecological transition of farms. This is even more important as very few studies on the subject have been undertaken and as there is a growing diversity of organizational forms of farms that differ from the traditional family model. This paper proposes a comprehensively integrated approach of dairy farms in Brazil. A case study of six archetypes of farms with contrasted organizational characteristics is developed to explore the relations between, on the one hand, farms’ organizational structure and governance, and on the other hand, the adoption of agri-environmental practices. Results show that the adoption of agri-environmental practices varies across the wide range of farm’s organizational forms—from the family to the industrial models. Farms with limited internal resources depend more specifically on external sectoral or territorial resources to implement environmental practices. If the environment is conducive to the creation of incentives and coordination mechanisms underlying learning processes, farms will adopt agri-environmental practices, regardless of they are organized. The creation of local cooperatives, farmer’s networks and universities extension programs can strengthen farmers’ absorption, adaptation and transformation capacities and boost the adoption of environmental practices. Finally, considering farms as heterogeneous organizational forms in terms of human capital, resources, market, and informational access is essential to accelerate the agroecological transition

Global Dairy Sector: Trends, Prospects, and Challenges

International audienceCurrently, there is a strong need to find practical solutions towards meeting the expected efficiency and overcoming recurring sustainability challenges in the global dairy sector. Improving dairy production and its supply chain explicitly depends on adopting a sustainable ‘state of the art’ based approach. Carefully evaluating and understanding certain key sustainability indicators through a holistic approach is highly imperative. Appropriate design and application of novel green technologies, implementation of life cycle analysis, upgradation and optimization of the entire production line are some of the most important factors to be considered. It is vital that due considerations are given to thedemands of the producers, consumers, and the dependent dairy industries. Nevertheless, in the future, concerns and challenges over the socio-economic–environmental security should not be ignored

Typology of Brazilian dairy farms based on vulnerability characteristics

International audienceVulnerability has been a recurring theme in animal production research around the world, as it can lead to a series of outcomes, such as abandonment of the activity. Nevertheless, in Brazil, the fifth-largest milk producer in the world, studies assessing dairy farmers' vulnerabilities are scarce. Better understanding of dairy farm vulnerability may contribute to reducing the consequences of vulnerability. In view of these limitations, we sought to analyze the typology of dairy farms based on vulnerability characteristics. We applied on-site questionnaires to 128 dairy farmers located in Paraná State, Brazil. Structural, productive, and socioeconomic data were collected and subjected to factor analysis. Two vulnerability indicators were identified: F1, productive and economic indicator; and F2, feed self-sufficiency indicator. Hierarchical cluster analysis of factor scores revealed three groups of dairy farms: Group 1, highly vulnerable; Group 2, less vulnerable; and Group 3, non-vulnerable. Dairy farms with higher vulnerability represented most of the sample, followed by less vulnerable and non-vulnerable dairy farms. Our findings indicated that the productive and economic characteristics of farms contributed the most to explaining differences in vulnerability, followed by feed self-sufficiency characteristics. Social characteristics of farmers were not important in differentiating the analyzed sample. There was an interdependent relationship between vulnerability indicators, namely productive and economic characteristics and feed self-sufficiency