31 research outputs found
Genome-wide association study identifies NRG1
- Author
- Cathy Ka-yee Shum
- Clara Sze-man Tang
- Danny Chan
- Elly Sau-wai Ngan
- Feng-qin Liu
- Gabriel
- Jin-fa Tou
- Kenneth Kak-yuen Wong
- Kenneth M. C. Cheung
- Kuhlbrodt
- Lei Liu
- Liu-ming Huang
- Man-ting So
- Maria-Mercè Garcia-Barcelo
- Ming-yiu Yeung
- Natarajan
- Pachnis
- Pak-chung Sham
- Paratore
- Paul Kwong-hang Tam
- Press
- Prigent
- Stacey S. Cherny
- Thomas Yuk-yu Leon
- Vincent Chi-hang Lui
- Wei-hong Guo
- Xiao-bing Sun
- Xiao-ping Miao
- Yan Chen
- You-qiang Song
- Zhen-wei Yuan
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- Field of study
Fine Mapping of the NRG1 Hirschsprung's Disease Locus
- Author
- AJ Law
- AS Brooks
- Benjamin Hon-Kei Yip
- Brian Man-Chun Leung
- C Paratore
- Clara Sze-Man Tang
- CP Torfs
- CS Tang
- DS Chekmenev
- EG Puffenberger
- Elly Sau-Wai Ngan
- ES Emison
- ES Emison
- Florian Kronenberg
- G Romeo
- Ivy Hau-Yee Chan
- J Amiel
- J Amiel
- Kenneth Kak-Yuen Wong
- L Mei
- M Angrist
- Man-Ting So
- Maria-Mercè Garcia-Barceló
- MM Garcia-Barcelo
- MM Garcia-Barcelo
- N Wakamatsu
- P Edery
- Pak-Chung Sham
- Patrick Ho-Yu Chung
- Paul Kwong-Hang Tam
- R Wieser
- RM Hofstra
- RM Hofstra
- RM Hofstra
- S Britsch
- S Britsch
- S Chen
- S Purcell
- SA Crone
- SI Ao
- Stacey S. Cherny
- Thomas Yuk-Yu Leon
- V Pingault
- Vincent Chi-Hang Lui
- Wai-Kiu Tang
- X Miao
- Xiao-Ping Miao
- Xuan-Zhao Wu
- Xue-Lai Liu
- Y Li
- Yan Chen
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
The primary pathology of Hirschsprung's disease (HSCR, colon aganglionosis) is the absence of ganglia in variable lengths of the hindgut, resulting in functional obstruction. HSCR is attributed to a failure of migration of the enteric ganglion precursors along the developing gut. RET is a key regulator of the development of the enteric nervous system (ENS) and the major HSCR-causing gene. Yet the reduced penetrance of RET DNA HSCR-associated variants together with the phenotypic variability suggest the involvement of additional genes in the disease. Through a genome-wide association study, we uncovered a ∼350 kb HSCR-associated region encompassing part of the neuregulin-1 gene (NRG1). To identify the causal NRG1 variants contributing to HSCR, we genotyped 243 SNPs variants on 343 ethnic Chinese HSCR patients and 359 controls. Genotype analysis coupled with imputation narrowed down the HSCR-associated region to 21 kb, with four of the most associated SNPs (rs10088313, rs10094655, rs4624987, and rs3884552) mapping to the NRG1 promoter. We investigated whether there was correlation between the genotype at the rs10088313 locus and the amount of NRG1 expressed in human gut tissues (40 patients and 21 controls) and found differences in expression as a function of genotype. We also found significant differences in NRG1 expression levels between diseased and control individuals bearing the same rs10088313 risk genotype. This indicates that the effects of NRG1 common variants are likely to depend on other alleles or epigenetic factors present in the patients and would account for the variability in the genetic predisposition to HSCR
RET Mutational Spectrum in Hirschsprung Disease: Evaluation of 601 Chinese Patients
- Author
- A Pelet
- Amr H. Sawalha
- Belinda K. Cornes
- Bin Wang
- BK Cornes
- Clara Sze-Man Tang
- Deli Zhu
- Diem Ngoc Ngo
- Elly Sau-Wai Ngan
- ES Emison
- ES Emison
- F Glaser
- FO Desmet
- Guo Cheng
- HH Won
- Hualong Wang
- Huimin Xia
- Ivy Hau-Yee Chan
- J Amiel
- JS Pedersen
- Juncheng Liu
- Kenneth Kak-Yuen Wong
- Liu-Ming Huang
- Long Cui
- Long Li
- M Garcia-Barcelo
- M Garcia-Barcelo
- M Seri
- Man-Ting So
- Maria-Mercè Garcia-Barcelo
- MM Garcia-Barcelo
- MM Garcia-Barcelo
- P Edery
- Pak-Chung Sham
- Patrick Ho-Yu Chung
- Paul Kwong-Hang Tam
- PS Tarpey
- RM Hofstra
- Ruizhong Zhang
- S Bolk
- S Manie
- SB Gabriel
- SP Dickson
- Stacey S. Cherny
- T Attie
- T Iwashita
- T Iwashita
- T Pupko
- Thanh Liem Nguyen
- Thomas Yuk-Yu Leon
- Vincent Chai-Hang Lui
- X Miao
- Xiao-Ping Miao
- Xuan-Zhao Wu
- Xue-Lai Liu
- ZE Sauna
- Zheng-Wei Yuan
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Rare (RVs) and common variants of the RET gene contribute to Hirschsprung disease (HSCR; congenital aganglionosis). While RET common variants are strongly associated with the commonest manifestation of the disease (males; short-segment aganglionosis; sporadic), rare coding sequence (CDS) variants are more frequently found in the lesser common and more severe forms of the disease (females; long/total colonic aganglionosis; familial)
Robust estimation of bacterial cell count from optical density
- Author
- Aarnio Tiu
- Aaron Leow Chung Yong
- Abbas Anser
- Abduraimova Aiganym
- Abraham Doris
- Acar Beliz Leyla
- Acosta Joaquin
- Adler Nina
- Adulyanukosol Natthawut
- Agena Ejouan
- Agena Ethan
- Aggarwal Priya
- Aguirre Adriana Lizeth Rubio
- Ahlgren Christopher
- Ahuja Janvi
- Aizik Dror
- Akbary Mina
- Akinfenwa Akinwumi
- Akingbesote Ngozi D.
- Akova Umut
- Aldo Ferdinan
- Alexopoulos Ioannis
- Allen Lucy
- Alonso Alejandro
- Altarawneh Dina
- Alvarado Andres Benjamin Sanchez
- Ambre Sanika
- Ameziane Annissa
- Amheine Khadija
- Amin Ihya Fakhrurizal
- Amir Sayeda Sakina
- Amstel Chiel van
- An Yongyan
- Anand Nithishwer Mouroug
- Ananthakrishnan Sathvik
- Anderson Karl
- Angel Sagi
- Annem Vidhya
- Anson Chung Tsun Ho
- Anwar Mariam
- Appel Alana
- Araya Lucas
- Armstrong Alexander
- Arora Neha
- Arora Vasu
- Arruda Beck
- Ashwin F Amal Jude
- Astapenka Artur
- Astles Ben
- Astorino Gabe
- Aubry Celine
- Avileli Rebecca
- Azad Mahnaz Sabeta
- Babar Rehmat
- Babu Priyanka
- Badalli Turan
- Badash Lior
- Baichman-Kass Amichai
- Baldwin Geoff S.
- Baltensperger Oliver Andreas
- Bao Guanke
- Bao Minyue
- Baronaite Ugne
- Barrat Leon Michael
- Barrington Seth
- Barshap Alon
- Bartzoka Natalia
- Basu Anubhav
- Basulto Cynthia
- Bath Scott
- Battina Rohith
- Bauersachs Daniel
- Beal Jacob
- Beale Renee
- Beard Eleanor
- Beck Selina
- Becker Evan
- Benavides Samantha Ayde Pena
- Bennis Nicole
- Bete Anna
- Bhatt Darshak
- Bhowmick Shilpa
- Bian Weixin
- Bijman Eline Yafele
- Bindt Felix
- Blas Karla Soto
- Bo Tang
- Boada Yadira
- Boer Meine
- Bohner Ariel
- Borovko Irina
- Bott Amie
- Bouwmeester Susan
- Bowman Kyle
- Boxem Mike
- Boxuan Cheng
- Boyce Kira
- Boyer Jess
- Brasas Valentas
- Brewer Mathew
- Briand William
- Brink Matilda
- Browne Emily
- Buckley-Taylor Russell
- Budhan Stephanie
- Buller Lisa
- Burckhardt Nele
- Burgland Zachary
- Burns Frank
- Burridge Matt
- Burud Hanna Nedreberg
- Buson Felipe Xavier
- Butterfield Tom
- Byagathvalli Gaurav
- Byatt Gabriel
- Byun Sumin
- Caballero Amalia
- Cai Fu
- Cai Niangui
- Caldwell Sarah
- Camacho Yazmin
- Camille Monteil
- Campbell Robert
- Cao Qinhao
- Cao Yixin
- Cao Yuze
- Carrillo Leo
- Carter Jonah
- Casas Alexis
- Castillo Nora Esther Torres
- Castillo Sandra
- Cave John
- Chai Ruochen
- Chamiec-Case Elizabeth
- Chan Janice
- Chan Yuan-Yao
- Chandramouli Priyanka
- Chang Annabel
- Chang Catherine
- Chang Kevin
- Chang Thomas
- Chang Ting-Chen
- Chang Yu-Ci
- Chapman Tyler
- Chater Dounia
- Chau Anthony
- Chavez Benjamin
- Chavez Francisco
- Chehade Ibrahim
- Chen Carmen
- Chen Chih-Chiang
- Chen Ching-Wei
- Chen Janice
- Chen Junhong
- Chen Junyang
- Chen Junyu
- Chen Pei-Hong
- Chen Ryan
- Chen Weixuan
- Chen Yan
- Chen Yi-Cian
- Chen Yifei
- Chen Zhuoyang
- Cheng Cheng
- Cheng Haolun
- Cheng Hsuan
- Cheng Yu-Hong
- Cheng Yu-Hsuan
- Chenxi Liang
- Cherupalla Arjun
- Chi Jordi
- Chi Shumei
- Chiang Jason
- Chiang Woody
- Ching Lai Tsz
- Ching Lam Kai
- Ching Law Hiu
- Ching Luk Hau
- Chinnathambi Sathivel
- Cho Sungwoo
- Choi Lee Sze
- Choi Youngeun
- Chou Ryan
- Chou Ryan
- Chu Wai Yan
- Chua Yah Tse Sabrina
- Chuang Yi-Chien
- Chulkova Nadezhda
- Chun Cheung Man
- Chun Emily
- Chun Ng Tsz
- Cifuentes Rodrigo Hernandez
- Clapper Jude
- Clapper Jude
- Clark Brittany
- Clemente Borja Sanchez
- Clerc Valerian
- Clodomir Christina
- Coates Ryan
- Cohen Katherine
- Colant Noelle
- Coleman Sarah
- Colgan Cian
- Cone Eli
- Corre Christophe
- Costa Ben
- Cott Rachel Van
- Craw Darilyn
- Crispim Larissa de Souza
- Crone Michael Andrew
- Crooijmans Marjolein
- Crosby Laurel Constanti
- Crowley Peter
- Cruz Frida
- Cubukcu Hande
- Culfogienis Dylan
- Czekster Clarissa
- Dai Leijie
- Dalangin Rochelin
- Daniel Benjamin
- Daniels Lea
- Das Neves Laura
- Das Diptatanu
- Davis Christina
- De Silva Nimaya
- Deb Shalini S.
- Deepak Kumar S.
- Deibel Emilie
- Dejoie Julianne
- Dejoux Alice
- DeKloe Jackson
- Del Toro Mariano
- Delalez Nicolas
- Delgadillo Sabrina
- Delhomme Jean
- Demchuk Aubrey
- Deng Nian Ruei
- Deng Rui
- Denter Jennifer
- Deshmukh-Reeves Ed
- Despres Philippe C.
- Devi Velvizhi
- Dhaliwal Gurpreet
- Diaz Fernanda
- Ding Shizhi
- Ding Yiming
- Ding Zhipeng
- Dingyue Tang
- Dirven Yvette
- Dissmann Jil-Sophie
- Do Stephanie
- Dogra Arushi
- Dominguez Viana Isabel Perez
- Dong Dongyang
- Dong Haitao
- Dong Jason
- Dong Shan
- Dong Shan
- Dong Shan
- Dong Shangzhi
- Dong Shangzhi
- Doyle David
- Doyle Shannon
- Dube Alexandre
- Dubuc Emilien
- Dunstan Izzy
- Dusseaux Theodore A.
- Dvorkin Steve
- Edelmayer Marco
- Ehrenworth Amy
- Eidloth Franziska
- Eijkens Bruno
- Eilers Keno
- El Moubayed Yorgo
- Elcin Evrim
- Elias Noel
- Elikan Max
- Ellermeier Craig
- Elliott Hannah
- Elsa Yeung Hoi Lam
- Emilov Kristian
- Espinoza Diego
- Evans Rhys
- Faidh Mohammed
- Falgenhauer Elisabeth
- Fan Catherine
- Fang Chengzhu
- Fang Choco
- Fang Xiangyi
- Farhi Einan
- Farias Sebastian
- Farny Natalie
- Farny Natalie G.
- Farrell Jennifer
- Fassler Jan
- Faurdal David
- Faustova Ilona
- Feng Xinhua
- Fernandez Cesar Ibrahym Rodriguez
- Fierro Daniela Olono
- Figueroa Ana Cristina
- Figueroa Jose Arnulfo Juarez
- Fikry Clara
- Filzen Rachael
- Fischer Matthew
- Fitzgerald Kevin
- Fitzgerald Liza
- Flores Vinicius
- Foda Asmaa
- Fong Yuhui Deborah
- Forman Victor
- Frank Stefanie
- Frankel Eva
- Freire Paulo J. C.
- Friedman Yonatan
- Frohlich Lisa
- Fu Wenhan
- Fu Yousi
- Fuentes Ernie
- Fulton Leah
- Fung Ip Ning
- Fung Yam Shing
- Gabrielli Jacopo
- Gahagan Maddison
- Gaitt Tobias
- Gaizauskaite Aukse
- Gallegos Isabella
- Gamoneda Diego
- Gandhi Rishi
- Gao Cecily
- Garavito Paula
- Garcia Chrismar
- Garcia David
- Garrido Delia
- Garulli Elisa
- Gaspar Camila
- Gaudi Alex
- Ge Gao
- Ge Yubin
- George Stephan
- Gerard Antoine
- Gershater Markus
- Ghosh Souvik
- Giannopoulos Alexandros Dimitriou
- Giannoula Yvoni
- Gilman Daniel Barber James
- Glockner Eleanor
- Goenka Anushya
- Goetz Marley
- Gogineni Namrata
- Gokul [NO FIRST NAME IN SCOPUS]
- Gonzalo Gonzalo Saiz
- Goodson Michael
- Gopaul Deshmukh
- Gou Yanchen
- Govers Jolijn
- Graaf Floor de
- Grace Tsui Shing Yan
- Graves Daniel
- Grazulyte Inga
- Greenwald Matthew
- Gu Jiajun
- Gu Yiheng
- Gu Yining
- Guadagnino Brett
- Guenther James
- Guerassimoff Lea
- Guo Jintao
- Gupta Shreya
- Guptil Chris
- Guseva Anna
- Ha Jacqueline
- Haddock-Angelli Traci
- Haight Travis
- Hale Mitch
- Hamady Carla
- Han Wang
- Han Weitang
- Handal Paola
- Hanrong Zhu
- Hansen Cecilie
- Hao Junyao
- Hao Mei
- Hao Zhengguo
- Haoran Xu
- Haralsvik Anne Kristin
- Hariyani Imtiyaz
- Hartley Zach
- Hassan Sondoss
- Hau Sion
- He Fa
- He Hanker
- He Henry
- He Karen
- He Lindong
- He Menglan
- He Peixiang
- He Yuna
- He Zhien
- Healy Liam
- Heath Emily
- Heger Theresa
- Hei Chan Yick
- Heijningen Franca van
- Heintze Maxime
- Hemmings Sam
- Heng Heng
- Heng Mary
- Henras Anthony
- Herbert Heydy
- Hernandez Ivan Martin
- Hernandez Laura Armero
- Herrmann Max
- Heux Stephanie
- Hewitt Amy
- Hiesinger Marlene
- Hill Kurt
- Hin Chan Lok
- Hin Wong Chung
- Hin Yu Man
- Ho Anthony
- Ho Ng Sze
- Ho Tim
- Hodson Sophie
- Hofer Sebastian
- Holman Olivor
- Holmedal Ingebjorg
- Hong Lai Tsz
- Hong Lee Chi
- Hong Yiquan
- Hong Yirui
- Horz Philip
- Hoskan Mehmet Ali
- Hosseini Reza
- Hou Ali
- Houmani Moustafa
- Hsiao Chia-Yi
- Hsieh Yi Da
- Hsu Chia-Wei
- Hsu Yi-Hsuan
- Hu Miao
- Hu Shi
- Hu Vivian
- Hu Wenyue
- Hu Xinyi
- Hu Yunyun
- Hu Zhaoqing
- Hu Zhiyuan
- Huang Fangliang
- Huang Jiaxi
- Huang Morris
- Huang Ray
- Huang William
- Huang Yansong
- Huang Yaohua
- Huang Yilin
- Huang Yinpin
- Huanying He
- HuaYue Zhang
- Huerta Ana Laura Torres
- Humphreys Christopher
- Hung Chia
- Husnatter Kai
- Huuki Liz
- Huynh Juilanne
- Hwang Michael
- Ibrahim Ahmed
- Ikagawa Yuichiro
- Ikhsan Muhammad
- Ikwuagwu Bon
- Imgold Markus
- Inanc Tugba
- Inckemann Rene
- Isaac Ashley
- Isaacs Farren
- Isogai Tatsuki
- Iwuogo Amanda
- Iyer Aditya
- Iyer Tvarita Shivakumar
- Izzati Nurul
- Jacq Annick
- Jain Rishabh
- Jain Shubham
- Jainarayanan Ashwin Kumar
- Jakutis Gabrielius
- Jaoui Samuel
- Japranata Valdi Ven
- Jaramillo Alfonso
- Jasiunas Simas
- Jasti Naveen
- Jay Leung Chung Yin
- Jayaraman Guhan
- Jayaraman Srimathi
- Jenakendran Jenaagan
- Jensen Joen Haahr
- Jesse Hayley
- Jha Aryaman
- Ji Peicheng
- Jiacheng Wu
- Jiahe Zhang
- Jiamiao Liu
- Jian Liu
- Jiang Nannan
- Jiang Zhenyu
- Jianzhao Yang
- Jiaqi Hu
- Jiaqi Xiao
- Jimenez Carlene
- Jin Kaifeng
- Jingjing Zhao
- Jinyu Zhu
- Jo Kyuhee
- Joe Lam Kai Ching
- Johnson Elizabeth
- Johnson Michael
- Jones Ari
- Jones Cara
- Jones Ethan
- Jones Megan
- Jones Melissa
- Jongkees Seino
- Jonsson Martin
- Jude Marcia Smiti
- Jung Younji
- Juskaite Ieva
- Justice Isaac
- Kabbara Ismat
- Kadimi Sricharan
- Kailash B.P.
- Kalinowski Jorn
- Kalinowski Jorn
- Kalson Pranshu
- Kamble Yash Laxman
- Kanata Eleni
- Kanaya Toshihiro
- Kang Han
- Kang Xu
- Kang Ziqi
- Kantas Gamze
- Kantor Nicole
- Kapsokefalou Maria
- Karpauskaite Laura
- Karpus Laurynas
- Karshenas Arman
- Karumanchi Pranathi
- Katherine Lai Man Wai
- Katopodi Xanthi Leda
- Kawasaki Yusuke
- Kayihan Ceyhun
- Keating Collin
- Kehan Tao
- Keidar Nitzan
- Keij Sander
- Kelly Ellis
- Kelly Julia
- Kennedy Fiona
- Kenneth Ng Tsz Chun
- Khaimani Jatin
- Khalid Alizah
- Khenwar Arundhati
- Kiga Daisuke
- Kim Anna
- Kim Christine
- Kim Dong Ju
- Kim Ellie
- Kim Gloria
- Kim Goeun
- Kim Grace
- Kim Sean
- Kin-ning Wong Carol
- King Stefanie
- Kittur M. Sagar
- Kiu Lee Hong
- Kiu Wong Hoi
- Kivisto Samu
- Klaas Liz
- Klopprogge Bjarne
- Ko LiangYu
- Kofoed Selma
- Kohabir Kavish
- Kolosova Anastasia
- Kong Cheng Chak
- Kong Linzhen
- Kortus Drew
- Koski Jessica
- Kostadima Eleni
- Kostopoulos Ioannis V.
- Kotzastratis Stylianos
- Kou Senhao
- Koutelidakis Antonios E.
- Kozhevnikov Adrian
- Krabacher Rachel
- Krainer Birgit
- Krauss Elisha
- Kristy Brandon
- Krokos Vasilios
- Kruger Dustin
- Krusemann Jan Lukas
- Kryukova Jhanna
- Ku Chi-Yao
- Kuang Yi
- Kuangyi Wei
- Kuebler Nadine
- Kugathasan Luxcia
- Kumar Adarsh
- Kumar Vignesh
- Kumbhojkar Ninad
- Kurian Jacob
- Kwasniak Dominika
- Kyrpizidis Grigorios
- Labecka Nikol
- Lahad Divangana
- Lai Evelyn
- Lai Evelyn
- Lam Chan Wing
- Lam Kendrick
- Lam Kevin
- Lam Yiu Choi
- Lang Jacob
- Lang Yusen
- Lassel Nicole
- Latham Michael
- Laun Sarah
- Laurel Ralph
- Laurentius Andrea
- Laury Jessica
- Lautru Sylvie
- Lawrence Jack
- Leach Cass
- Leal Luis Mario
- Ledalla Karthik
- Lee James
- Lee Jordan
- Lee Matthew
- Lee Meixuan
- Lee Meng-Zhan
- Lee Yeonjae
- leelahakorn Nattawut
- Leeuw Monique de
- Lefevre Marine
- Lehtonen Leevi
- Leitner Karl
- Lekshmi Hema
- Lemieux Pascale
- Leon Karen De
- Lepetit Florian
- Levrier Antoine
- Li Caidian
- Li Changyu
- Li Hailong
- Li Haocong
- Li Jiadong
- Li Kevin
- Li Nuonan
- Li Peilin
- Li Sophie Ruojia
- Li Tingting
- Li Tingting
- Li Tingyue
- Li Xuecheng
- Li Yanyan
- Li Yuanyuan
- Li Yuqi
- Li Zihao
- Li Zonghao
- Liang Tommy
- Liang Yuteng
- Liang Zhihan
- Liangjian Yang
- Liao Chin-Hsuan
- Liaoqi Du
- Lichi Fang
- Lim Sangwu
- Lim Yan Ping
- Lima Guilherme Meira
- Lin Beatrix Tung Xue
- Lin Chenyi
- Lin Junliang
- Lin Weifeng
- Lin Yasmin
- Lin Yu-Chun
- Lind Andrea Clausen
- Linke Dirk
- Litsa Maria
- Liu Fangqi
- Liu Huan
- Liu Jiangyuan
- Liu Jiezheng
- Liu Jingang
- Liu Ting
- Liu Wei-Ting
- Liu Weijia
- Liu Wukun
- Liu Xiaolong
- Liu Xutong
- Liu Yiheng
- Liu Yuansheng
- Liu Zhaoyu
- Liu Zhihao
- Liu Zhixiang
- Liu Zi
- Liya Devang Haresh
- Lo Natalie
- Lockwood Savannah
- Loeffler Frank
- Logel Dominic
- Loke Chun Kit
- Lombardero Francisco Javier Quero
- Longo Ylenia
- Loog Mart
- Lopez-Grado Guillem
- Lorch Kevin
- Lortie Louis-Andre
- Lotz Thea
- Louis Simon
- Lu Chenyu
- Lu Yinjing
- Luan Lin
- Luo Chenfei
- Luo Claire
- Luo Fang
- Luo Linda
- Luo Liudong
- Luo Mingyue
- Luo Xiaofan
- Luo Zhi
- Luque Ana Cecilia
- Luzuriaga Juan Carlos
- Lykkegaard Magnus Ronne
- Ma Guanghui
- Ma Jiaxin
- Ma Liang
- Ma Lingling
- Ma Yingqi
- Ma Yuan
- Maddiboina Dhanyasri
- Madelenat Manon
- Madrid Micah
- Magzoub Mazin
- Mahapatra Nitish R.
- Maljavin Artemi
- Mancinotti Davide
- Mangkusaputra Venda
- Mansfield Laura
- Mao Jiangjiao
- Marcoleta Andres
- Marinovic Adrian
- Marken John
- Markiv Anatoliy
- Marquina D.
- Marta Britany
- Marti Marcos Vega-Hazas
- Martin Michael
- Martinelli Adriano
- Martinez Antonio
- Martinez Victor Javier Robledo
- Maruo Tatuya
- Matheis Anna
- Matiyevskaya Frida
- Mattens Jard
- Matthew Cheah
- Maupu Clemence
- Mayer Julia
- Mazelis Ignas
- McConnell Kelton
- McDonald Dallas
- McDonough Matt
- McShane Evie
- Meas Catherosette
- Medina Maria Jose Ramos
- Meerbrei Tanja
- Meirkhanova Ayagoz
- Mejlsted Jacob
- Mellou Areti-Efremia
- Menart Peter
- Mendoza Adrian Federico Hernandez
- Meneu Lea
- Menghan Gao
- Mengtao Du
- Menon Sarvesh
- Mertes Verena
- Meyer Lasse
- Meyfarth Oda-Emilia
- Miao Xinyi
- Miao Zhoudi
- Michelsen Stephanie
- Milano Fiona
- Mills Channah
- Milshtein Eliya
- Ming Shaw Kar
- Mingge Li
- Mishler Dennis M.
- Mishra Vibhu
- Mitropoulos Alex
- Mo Yilin
- Mohan Kumar B.S.
- Moncayo Eduardo
- Moreira Natalia Torres
- Mori Yuya
- Morrison Shikei
- Moscoso Ricardo
- Mota Mariana Santana da
- Mubeen Sara
- Mueller Julia
- Mukhanova Assel
- Mulikova Tomiris
- Mullin Matthew
- Munoz Felipe
- Murugan Santosh
- Muthukrishnan Anantha Barathi
- Myers Karl
- Neda Andrei
- Ngo Cheng Tsz
- Nguyen Aerilynn
- Nguyen Judy Van
- Ni Haochen
- Nianlong Li
- Nicholson Kyle
- Nickels Elena
- Nieberding-Swanberg Jolee
- Nielsen Lina
- Nijenhuis Janine
- Ning Hsiu Ou
- Niu Wei
- Niu Xubo
- Niwa Ryo
- Norberg Axel
- Norvaisaite Ieva
- Notheisen Jan
- Ntekas Ioannis
- Nunez Anna Karen Aguilar
- Nurachman Luthfian Aby
- Obaji Daniel
- Obrvan Marko
- Oetelaar Maxime van den
- Oliveira Nina De Sousa
- Oliver Adam
- Ollessa-Daragon Xavier
- Olmin Amanda
- Ong June
- Oropeza Carlos Javier Cordero
- Oser Eden
- Oswald Andreas
- Otto Matthias
- Otto Matthias
- O’Brien James
- O’Leary Travis
- Paez Timmy
- Pageni Aroma
- Pai Sveekruth Sheshagiri
- Palo Sara
- Pan Catherine
- Pan Lin Yu
- Pan Luyao
- Pan Yuyao
- Pang Chung Him
- Pang Yibo
- Pange Nishtha
- Papadopoulo Kenn
- Parab Komal
- Park Kevin
- Park Mikyung
- Park Seunghyun
- Parmar Jasmeen
- Parmentier Mathieu
- Parr Lillian
- Parry Geraint
- Partridge Daniel
- Pasi Mor
- Pate Kaylee
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- Zamora Alejandro Robles
- Zanoni Paul
- Zanotti Violetta
- Zeng Chenxu
- Zeng Yuanhong
- Zepeng Xu
- Zerva Anastasia
- Zhan Yang
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- Zhang Wanli
- Zhang Xianyin
- Zhang Xinyu
- Zhang Yihao
- Zhang Yuanzhen
- Zhang Yunqian
- Zhang Zixuan
- Zhao Nannan
- Zhao Peng
- Zhao Tianyan
- Zhao Wenxue
- Zhao Yihang
- Zhaoting Li
- Zhecheng Huang
- Zheng Daniel
- Zheng Jiyang
- Zhiwei Song
- Zhong Yanling
- Zhou Hanmi
- Zhou Jiajie
- Zhou Jianan
- Zhou Rui
- Zhou Shuyao
- Zhou Xuanhao
- Zhou Yanjun
- Zhou Yi
- Zhou Yinchi
- Zhou Yineng
- Zhou Yuezhang
- Zhou Yuxin
- Zhou Zhiyu
- Zhu Chushu
- Zhu Ke
- Zhu Xueqian
- Zi Lihan
- Zilinskaite Nemira
- Zimmermann Andreas
- Zimmermann Jennifer
- Zirong Zeng
- Ziwei Zhou
- Ziyi Zhao
- Zorrilla Francisco
- Zou Jiahua
- Zukauskaite Kristina
- Zulueta Patricia
- Zvirblyte Justina
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
AI is a viable alternative to high throughput screening: a 318-target study
- Author
- Abaffy Tatjana
- Abraham Elena Theres
- Abrahão Jônatas Santos
- Abramyan Tigran M.
- Agianian Bogos
- Agogo-Mawuli Percy
- Agoulnik Alexander I.
- Agrawal Rajendra K.
- Aguilera Elena
- Ahmed Mostafa
- Akk Gustav
- Akopian Tatos
- Al-Yozbaki Minnatallah
- Aldhamen Yasser Ali
- Alkan Cigdem
- Alramadhani Dina
- Alteen Matthew G.
- Alvarez Guzmán
- Ammendola Serena
- Anastasio Noelle C.
- Anderson Brandon M.
- Anderson Deborah H.
- Andricopulo Adriano D.
- Angell Richard M.
- Anthis Nicholas J.
- Antonelli Lorenzo
- Apfel Athena Marie
- Arias Juan Antonio Sanchez
- Arozarena Imanol
- Arrigoni Cristina
- Artía Zoraima
- Ashkar Shireen R.
- Ashton Mark R.
- Austin Richard C.
- Ayachi Aicha Gharbi
- Azeem Syeda Maryam
- Bailey-Elkin Ben A.
- Balakrishnan Bijina
- Balaña-Fouce Rafael
- Ballatore Carlo
- Banerjee Sourav
- Banerji Versha
- Banjo Toshihiro
- Barghash Marim M.
- Batey Robert A.
- Battistoni Andrea
- Baumann Ulrich
- Bdira Fredj Ben
- Bedi Mel
- Ben-Johny Manu
- Bergman Bastiaan
- Bernard Denzil
- Berti Andrew
- Bharambe Nikhil
- Bishop Ozlem Tastan
- Blanchet Xavier
- Blelloch Robert
- Blumenthal Robert M.
- Bognár Gabriella
- Bogomolovas Julijus
- Bon Carlotta
- Boorman Jacob
- Borowska Anna
- Borriello Francesco
- Bowman Gregory R.
- Bradley Robert K.
- Bradshaw William J.
- Brady-Kalnay Susann M.
- Breton Hairol E.
- Bruning John B.
- Bruning John Burt
- Bryant-Friedrich Amanda
- Buckner Frederick S.
- Buroni Silvia
- Butler Brittany
- Byrne Lee J.
- Byun Soo Young
- Caflisch Amedeo
- Cakir Isin
- Caliandro Ileana
- Caljon Guy
- Cann Andrew B.
- Caporali Andrea
- Capuzzi Stephen J.
- Caroleo Maria Cristina
- Cathcart Ann M.
- Celano Stephanie L.
- Cerna Mark Vincent C. dela
- Chadni Somaia Haque
- Champion Matthew M.
- Chan Nei-Li
- Chapman Carly J.
- Chaton Catherine T.
- Chatterjee Arnab K.
- Chaudhuri Dipayan
- Chauhan Shefali
- Chaytow Helena
- Chen Daniel
- Chen Lifeng
- Chen Yicheng
- Chern Ting-Rong
- Chini Andrea
- Chou Tristan
- Chou Tsui-Fen
- Christensen Emily M.
- Christodoulides Myron
- Chu Shaoyou
- Chua Benjamin Soon Kai
- Chuah Janelle
- Chung Zara
- Chuong Patrick
- Ciccia Alberto
- Cildir Gökhan
- Cione Erika
- Clayton W. Brent
- Coles John G.
- Colomba Audrey
- Colotti Gianni
- Conn Graeme L.
- Conticello Silvestro G.
- Contreras Stephanie
- Cools Julie
- Coombe Deirdre R.
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- Cortopassi Gino
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- Cowen Leah E.
- Cox Bryan D.
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- Cunningham Kathryn A.
- Dahal Gopal
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- de Oliveira Aldo Sena
- de Oliveira Saulo
- de Sousa Alessandra Mara
- de Souza Guilherme Eduardo
- Debonsi Hosana Maria
- Degterev Alexei
- DeHaan Nicholas
- Del Rio Flores Antonio
- Dempsey Garrett
- Desai Umesh R.
- Diallo Bakary N’tji
- Dickhout Jeffrey
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- Dirksen Dorian
- do Monte-Neto Rubens Lima
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- D’Antuono Anna
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- ElSheikh Assmaa
- Englinger Bernhard
- Escaffre Olivier
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- Feng Hui
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- Foote Andrea Talbot
- Francisco Karol R.
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- Gavathiotis Evripidis
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- Gelardi Edoardo Luigi Maria
- Gerwick William H.
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- Ghosh Agnidipta
- Giardini Miriam A.
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- Gillingwater Thomas H.
- Gingras Alexandre R.
- Giorgis Marta
- Girolimetti Giulia
- Glubb Dylan M.
- Glukhov Evgenia
- Gniewek Pawel
- Goldenberg Joshua M.
- Gong Bin
- Gorgoglione Ruggiero
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- Guido Rafael V. C.
- Gumede Njabulo Joyfull
- Gunasekharan Vignesh
- Gupta Tushita
- Gupta Yogesh K.
- Gustincich Stefano
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- Houry Walid A.
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- Hu Di
- Hu Yanmei
- Huang Chang
- Huimei Chen
- Hussain Muhammad Saddam
- Iglesias Pablo
- Ikegami Tetsuro
- Ilari Andrea
- Inde Zintis
- Ingoglia Filippo
- Iommarini Luisa
- Ip Philbert
- Jackson Michael R.
- Jafar-Nejad Hamed
- Jayasinghe Thilina D.
- Jo Eunji
- Johannsen Sandra
- John Ashley L. St.
- Jones Peter L.
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- Jung Hoyoung
- Kahler Charlene M.
- Kampourakis Thomas
- Kandror Olga
- Karan Charles
- Katyal Sachin
- Kee Jung-Min
- Kee Jung-Min
- Keedy Daniel A.
- Kejriwal Rishabh
- Keller Charles
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- Kemet Chinyere Maat
- Kenyon Victor
- Kerr William G.
- Khalaf Noureddine Ben
- Kilkenny Mairi Louise
- Kim Hyeong Jun
- Kim Kyu Kwang
- Kootstra Neeltje A.
- Koppisetti Rama K.
- Korotkov Konstantin V.
- Kotzé Timothy J.
- Kováts Benjámin
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- Krishnamurthy Durga
- Krist David T.
- Kroon Erna Geessien
- Kushnir Alexander
- Kwiatkowski Jacek
- Laggner Christian
- Lai Kent
- Lake Robert J.
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- Lama Eleonora
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- Lasarte Juan José
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- Lee Kyung Hyeon
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- Legare Scott
- Lehtiö Lari
- Lembo Gaia
- Lempicki Camille
- Lenci Elena
- Leng Fenfei
- Lescar Julien
- Leung Elisa
- Leuzzi Giuseppe
- Levin Michael
- Li Hai
- Li Shan
- Li Wei
- Li Yihe
- Li Yong
- Li Yunlong
- Liao Jiayu
- Liao Junzhuo
- Lieberman Howard B.
- Lin Jiabei
- Lin Jiusheng
- Liou Benjamin
- Lisabeth Erika Mathes
- Liu Chen
- Liu Koting
- Liu Pengda
- Liu Pengda
- Liu Zhongle
- Lobb Kevin A.
- Lolicato Marco
- Lolli Marco Lucio
- Longo Nicola
- Lotsaris Irina
- Lowther W. Todd
- Loy Cody A.
- Lu Xin
- Luh Frank
- Lukacs Gergely L.
- Luo Dahai
- Lussier Marc P.
- Lynn Edward G.
- Machaca Khaled
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- MacKeigan Jeffrey P.
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- Maksimainen Mirko M.
- Malkas Linda H.
- Maltarollo Vinícius Gonçalves
- Mameli Eleonora
- Manor Danny
- Mantri Chinmay Kumar
- Maranda Vincent
- Martin Katie R.
- Martin-Malpartida Pau
- Maruta Shinsaku
- Marx Steven O.
- Mason Emily R.
- Matheeussen An
- Matovic Nick
- Mattevi Andrea
- Maurice Martin St.
- Mayer Gaétan
- Maynes Jason T.
- Mazitschek Ralph
- McCarthy Ronan R.
- McDowell Mary Ann
- McManus Kirk James
- Mehedi Masfique
- Mehlman Tamar
- Mellado Mario
- Mellor Paul
- Merrill Nathan M.
- Michlewski Gracjan
- Milosavljevic Julian
- Minakova Anna
- Miner Jaden
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- Montanaro Anna
- Moore Hannah P.
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- Moreda Teresa Lozano
- Moreira David
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- Morisseau Christophe
- Morrison Adrian
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- Mostert Konrad J.
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- Motyl Anna A. L.
- Mousa Jarrod J.
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- Mushtaq Aisha
- Musta Kirsikka
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- Müller Christa E.
- Myhr Courtney
- Mysinger Michael
- Mysore Venkatesh
- Nagai Maira Harume
- Nagamori Kiyo
- Namasivayam Vigneshwaran
- Nasburg Joshua Alexander
- Ng Ho Leung
- Ng James
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- null null
- Ogunwa Tomisin Happy
- Ojha Anil K.
- Ojo Kayode K.
- Olson Steven H.
- Ortiz Diana
- Oyarzabal Julen
- O’Brien Terrence E.
- O’Connell Patrick
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- Palazzo Teresa
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- Petretto Enrico
- Pérez-Pertejo Yolanda
- Phadke Sameer
- Pham Kien
- Pineda-Lucena Antonio
- Poirier Steve
- Popowicz Grzegorz Maria
- Porcelli Anna Maria
- PrasadPrasad Srimukh Veccham Krishna
- Presser Adam G.
- Pressly Brandon
- Prikler Gergely
- Prince Ashutosh
- Puchades-Carrasco Leonor
- Pusztai Lajos
- Qi Xin
- Qin Xingping
- Qureshi Insaf Ahmed
- Rabal Obdulia
- Radhakrishnan Senthil K.
- Ramachandran Rajesh
- Randall Lía M.
- Rangarajan Amith Vikram
- Rayman Joseph B.
- Reglero Clara
- Reguera Rosa Maria
- Reidenbach Andrew G.
- Reis Joana
- Ribeiro Beatriz Murta Rezende Moraes
- Richardson Timothy I.
- Riches David W. H.
- Rizzi Menico
- Robinson Victoria L.
- Rocha Rafael Eduardo Oliveira
- Rodriguez G. Marcela
- Rodríguez-Frade José Miguel
- Rohde Kyle H.
- Ronchi Virginia Paola
- Ronning Donald R.
- Rosnik Andreana
- Roti Giovanni
- Rouzbeh Nirvan
- Rowswell-Turner Rachael B.
- Rubin Eric J.
- Rucinski Gwennan
- Safo Martin K.
- Sainas Stefano
- Salas Brenda P. Medellin
- Samantha Ariela
- Samudio Ben
- Santiago César
- Sarangapani Krishna
- Sarilla Suryakala
- Sarosiek Kristopher
- Schneider Nicholas O.
- Schroedl Stefan
- Scoffone Viola Camilla
- Segers Vincent F. M.
- Seo Seung-Yong
- Serafim Mateus Sá Magalhães
- Shaqra Ala M.
- Shek Stefani
- Shelburne Samuel A.
- Shim Heesung
- Shorter James
- Shoue Douglas A.
- Shum David
- Shyng Show-Ling
- Siderovski David P.
- Sidorova Yulia A.
- Silva Elany Barbosa
- Silvennoinen Olli
- Singh Nathanael
- Singh Neeraj
- Singh Rakesh K.
- Siqueira-Neto Jair L.
- Sishtla Kamakshi
- Sistla Jyothi C.
- Skorodinsky Maxim
- Slotboom Dirk J.
- Smith David M.
- Smith Kristiana S.
- Smrcka Alan V.
- So Jonathan
- Sobrado Pablo
- Soellner Matthew B.
- Solano Roberto
- Sorenson Jon M.
- Stafford Kate
- Stahl Andreas
- Statsyuk Alexander V.
- Stec Natalia
- Stecula Adrian
- Stetefeld Joerg
- Strauss Erick
- Stuchbury Grant David
- Su Leila
- Su Tong
- Su Zhengchen
- Sugamori Kim S.
- Sun Ying
- Suterwala Shabbir
- Svensson Fredrik
- Sverzhinsky Aleksandr
- Swart Tarryn
- Taglialatela Angelo
- Tam Heng-Keat
- Tandon Vasudha
- Tang Weiping
- Tang Young
- Tanner John J.
- Taylor Richard E.
- Teixeira Thaiz Rodrigues
- Teramoto Tadahisa
- Thai Van Chi
- Thayer Desiree
- Thomas Bill
- Thompson Erik W.
- Tilford Hannah
- Tiwari Rakesh Kumar
- Toh Alan Kie Leong
- Tomilov Alexey
- Toogood Peter
- Torner Carles
- Trabocchi Andrea
- Trader Darci J.
- Trakhtenberg Ephraim F.
- Trinh Nguyen Mai
- Truong Ha
- Tse-Dinh Yuk-Ching
- Tsimbalyuk Sofiya
- Tumes Damon J.
- Tye Mark A.
- Uribe Ruben Vazquez
- Valli Marilia
- van den Akker Focco
- van den Bedem Henry
- Van Doren Steven R.
- Van Grack Tessa
- Van Hung Le Vuong
- Van Pelt Natascha
- Van Remmen Holly
- Van Voorhis Wesley C.
- Vandenberg Robert J.
- Veit Guido
- Verhamme Ingrid M.
- Verma Rajkumar
- Viola Ronald E.
- Virtanen Anniina
- Vizeacoumar Franco J.
- Vizeacoumar Frederick S.
- Vleminckx Margot
- von Hundelshausen Philipp
- Voss Jan Hendrik
- Vrielink Alice
- Waggoner Stephen N.
- Walensky Loren D.
- Wallach Izhar
- Wang Feng
- Wang Jianghai
- Wang Jun
- Wang Xingyou
- Wang Zhenghe
- Warrington Jeffrey M.
- Watkins Joshua
- Wazir Sarah
- Weber Christian
- Welsbie Derek S.
- Wentworth Kelly L.
- Wert-Lamas Leon
- White Andrew
- White Simon J.
- Whitesell Luke
- Williams Tiffany
- Wilson Cornelia M.
- Wilson Mark A.
- Windisch Marc P.
- Wong Keith S.
- Woods Virgil A.
- Worley Brad
- Wu Pengpeng
- Wu Xiaoyang
- Wulff Heike
- Xiang Fei
- Xu Hongyang
- Xu Jiake
- Xu Jingyi
- Xu Sophia Q.
- Xu Xin
- Yan Riqiang
- Yang Chao-Yie
- Yen Yun
- Young Matthew A.
- Yu Fang
- Yu Xinfang
- Yuan Haynes
- Yuan Xinrui
- Zahler Stefan
- Zeina Christina M.
- Zelinskaya Natalia
- Zhang Dingqiang
- Zhang Gang
- Zhang Wenjun
- Zhang Xu
- Zhang Yan Jessie
- Zhang Zhiguo
- Zhao Jinshi
- Zhou Han
- Zhou Hui
- Zhou Jia
- Zhou Pei
- Zhou Shan
- Zhu Jiaqi
- Zhu Siran
- Zhu Yini
- Zhuo Ling
- Zochodne Douglas William
- Publication venue
- Publication date
- 01/01/2024
- Field of study
: High throughput screening (HTS) is routinely used to identify bioactive small molecules. This requires physical compounds, which limits coverage of accessible chemical space. Computational approaches combined with vast on-demand chemical libraries can access far greater chemical space, provided that the predictive accuracy is sufficient to identify useful molecules. Through the largest and most diverse virtual HTS campaign reported to date, comprising 318 individual projects, we demonstrate that our AtomNet® convolutional neural network successfully finds novel hits across every major therapeutic area and protein class. We address historical limitations of computational screening by demonstrating success for target proteins without known binders, high-quality X-ray crystal structures, or manual cherry-picking of compounds. We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
- Author
- Abdel-Rahman Emaad
- Abhayaratna Walter
- Abramof Ness Rosane
- Acosta Idalia
- Adams Atoya
- Adawi Faiad
- Adler Sharon
- Ahmed Fayzal
- Aizenberg Diego
- Ajani Dilawar
- Al-Karadsheh Amer
- Albota Adrian
- Alferi Dino
- Alicic Radica
- Alla Sreedhara
- Allison D
- Almeida Edgar
- Alpizar Salazar Melchor
- Amer Joseph
- Amod Aslam
- Andrawis Nabil
- Antonio Bossi Carlo
- Antsiferov Mikhail
- Antunes Daniela
- Araki Hideo
- Arango Clara
- Arcos Edgar
- Arif Ahmed
- Arif Imrozia
- Arkhipov Mikhail
- Armaly Zaher
- Aroca Gustavo
- Asprusten Emil
- Atar Shaul
- Avila Pardo Sandro
- Awad Ahmed
- Axthelm Christoph
- Azizad Masoud
- Azizah Aziz Nor
- B Brouwer C
- Babikova Jana
- Babkin Andrey
- Badak Ozer
- Bahrami Michael
- Bajcsi Dora
- Baker John
- Bala Cornelia
- Ballesteros Rosa
- Bansal Shweta
- Barag Steven
- Barakzoy Ahmad
- Baranov Vitaliy
- Barbarash Olga
- Barbonta Hortensia
- Barney Mark
- Barre Paul
- Barrera Sandra
- Barreto Carlos
- Barreto Germ\ue1n
- Bartolacci In\ue9s
- Bashir Khalid
- Bashkin Amir
- Bastidas Adrian Miriam
- Bautista Albert
- Bautista Jose
- Bech Jesper
- Beddhu Srinivasan
- Beltr\ue1n L\uf3pez Nelly
- Ben Chetrit Sydney
- Benitez Diego
- Benjamin Sabrina
- Berar Yanay Noa
- Berenji Ramin
- Bertram Pitt
- Bertsch John
- Besada Diego
- Bhana Sindeep
- Bhargava Anuj
- Bilz Stefan
- Birkenfeld Andreas
- Birriel Jose
- Bittar Julio
- Blanco Guillermo
- Bleich David
- Boletis Ioannis
- Bondarets Iryna
- Bonora Enzo
- Bornfreund Jonathan
- Boshnyashka Radostina
- Botelho Roberto
- Botero Rodrigo
- Botsyurko Volodymyr
- Bouarich Hanane
- Brada Michal
- Brandao Ilidio
- Brar Harjeet
- Braun Hermann
- Brezina Jiri
- Brian Susan
- Brietzke Stephen
- Brito Claudia
- Bruchfeld Annette
- Bruno Giorda Carlo
- Brusco Osvaldo
- Bu Ruifang
- Bucek Petr
- Buganova Ingrid
- Burgner Anna
- Busch Klaus
- Busch Robert
- Butrymowicz Patrycja
- C Bakker R
- C\ue1rdenas Tatiana
- Caceaune Elena
- Cai Hanqing
- Calabr\uf2 Paolo
- Calero Francesca
- Canadas Rafael
- Canani Luis
- Caramori Maria
- Cardona Jose
- Cariou Bertrand
- Carlo Maggi Davide
- Carlos Palma Juan
- Carlos Prieto Juan
- Carlson Brian
- Carpio Jose
- Carvalho Rui
- Case Christopher
- Castro Cristina
- Catindig Elizabeth
- Catrinoiu Doina
- Cayli Murat
- Cereto Castro Fernando
- Cerqueira Maria
- Chahin Mariano
- Chang Chiz-Tzung
- Chantrel Fran\ue7ois
- Chen Dejun
- Chen Nan
- Chen Qinkai
- Cheng Jinluo
- Chernikova Viktoriia
- Chernin Gil
- Chernyavskaya Elena
- Chew Wong Alfredo
- Christina Nowack
- Chuang Lee-Ming
- Chung ChoonHee
- Ciechanowski Kazimierz
- Cieslik Grazyna
- Cigarr\ue1n Guldris Secundino
- Cimino Roberto
- Clavel Sylvaine
- Clodi Martin
- Cobos Jorge
- Colman Peter
- Colquhoun David
- Constantin Ciprian
- Contzen Christel
- Conway James
- Coronel Julian
- Cortes-Maisonet Gregorio
- Cortes-Maisonet Gregorio
- Cournoyer Serge
- Crawford Veronica
- Cristina Gregorini Maria
- Cruz Humberto
- Cruzado Garrit Josep
- Cure Carlos
- Curiac Dan
- Cutfield Rick
- Dandillaya Ramprasad
- Dang Cuong
- Danos Peter
- Darawsha Mahmud
- de \uc1lvaro Fernando
- de Paula Rogerio
- Deerochanawong Chaicharn
- Degenhardt Stefan
- Demko Arkadiy
- Derwahl Karl
- Dhanireddy Soni
- Din Zia
- Distiller Larry
- Dixon Bradley
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- Dong Youping
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- Doubel Peter
- Dreval Alexander
- Drexel Heinz
- Du Yuming
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- Dunn Peter
- Dur\ue1n Carlos
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- E Costa Fernando Teixeira
- Ebenbichler Christoph
- Ebisui Osamu
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- Edin Anton
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- Elbert Alicia
- Elias Mazen
- Eliaschewitz Freddy
- Eliasson Ken
- Emdin Michele
- Engelen Wendy
- Eren Necmi
- Eriksen Erik
- Ermakova Polina
- Escalada San Mart\uedn Javier
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- Esteves Cesar
- Eugenia Canziani Maria
- Eustace Joe
- Evans John
- Faber Jens
- Fadda George
- Fang Sum Chee
- Fang Yi
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- Farah Ghassan
- Farber Evgeny
- Farooq Umar
- Fauvel Jean-Pierre
- Fernando Roland
- Fiaccadori Enrico
- Fikry Sameh
- Fink Raymond
- Finnes Trine
- Fiorina Paolo
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- Fitz-Patrick David
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- Fluck Patrick
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- Forti Adriana
- Franek Edward
- Frank Malin
- Frias Juan
- Fujita Naruhiro
- Furuya Ryuichi
- Fushtey Ivan
- G Lieverse A
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- Gallouj Karim
- Galphin Claude
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- George L Bakris
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- Giebel Thomas
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- Gonzalez Edgar
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- Gore Ashwini
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- Guo Weiying
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- Guzm\ue1n Gustavo
- H Boonstra A
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- Habwe Violet
- Hagemeier Robert
- Hagenow Andreas
- Halabi Majdi
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- Hamasaki Akihiro
- Hamet Pavel
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- Hammoud Jamal
- Handelsman Stuart
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- Hanna Fahmy
- Hanusch Ursula
- Hao Chuanming
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- Hart Randolph
- Hartman Israel
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- Hatziagelaki Erifili
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- Heigerick Glenn
- Heitor Susana
- Hellberg Olof
- Hellgren Margareta
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- Hern\ue1ndez Eric
- Hernandez German
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- Herrera Carlos
- Higashi Takayuki
- Hirohata Yoshihide
- Hissa Miguel
- Hoffmann Michal
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- Holian John
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- Hougardy Jean-Michel
- Hrmova Helena
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- Hung Cheng-Chieh
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- Ibarra Jaime
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- Imoto Hirofumi
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- Inagaki Masayuki
- Ioannidis Ioannis
- Ipatko Irina
- Iranmanesh Ali
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- Ishiko Tamayo
- Jackson Timothy
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- Jamerson Kenneth
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- Jaramillo Carlos
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- Jaroslaw Pacyk Grzegorz
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- Jiang Ju-Ying
- Jiang Sheng
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- Johnson Karen
- Joshi Mukesh
- Joshi Shaifali
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- Kounadi Theodora
- Kovacs Laszlo
- Kovar Richard
- Kovesdy Csaba
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- Kr\ufcger Thilo
- Krarup Thure
- Kravchun Nonna
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- Krebs Jeremy
- Kreit Camil
- Krekels Marielle
- Kriauciuniene Dovile
- Krishna Arvind
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- Kuang Jian
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- Kurnatowska Ilona
- Kusano Yoshiro
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- Kvitkova Lyudmila
- Kyriakidou Christina
- L Penne E
- L\uf3pez M\uf3nica
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- Lahtela Jorma
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- Ludvik Bernhard
- Luigi Cavalot Franco
- Luis M Ruilope
- Lurie Alexander
- M Barendregt J N
- M van Leendert Ruud J
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- M\ufcller Joachim
- Ma Jianhua
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- Ohashi Hiroshi
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- Rymar Oksana
- Ryu Jeffrey
- S\ue1nchez Juan Carlos
- S\ue1nchez Gregorio
- Saavedra Victor
- Sadeharju Karita
- Sahani Mandeep
- Sahin Idris
- Salda\uf1a Mendoza Arturo
- Samuels Garfield
- San Tan Ru
- Sanabria Hugo
- Sanchez William
- Santamar\ueda Olmo Rafael
- Santorelli Gennaro
- Santoro Domenico
- Sardinov Ruslan
- Sari Ramazan
- Sarvan Mohamed
- Sasaki Nobuhiro
- Satirapoj Bancha
- Sauque Reyna Leobardo
- Saxena Sanjeev
- Sch\uf6ll Norbert
- Sch\uf6nherr Hans-Robert
- Sch\ufcrholz Thomas
- Scheen Andr\ue9
- Schernthaner Gerit-Holger
- Schettler Volker
- Schiefke Ingolf
- Schlichthaar Heike
- Schneider Karoly
- Schousboe Karoline
- Schr\uf6ppel Bernd
- Schwartz Daniel
- Schwartz Doron
- Scott David
- Scott Russell
- Seco Gilberto
- Seeber Mary
- Sekigami Taiji
- Sels\ue5s Hilde
- Semenova Olga
- Serhiyenko Oleksandr
- Seron Daniel
- Serota Harvey
- Serusclat Pierre
- Shafi Tariq
- Shahid Nauman
- Shanik Michael
- Sharma Santosh
- Shen Feixia
- Shen Jiansong
- Sherenkov Alexander
- Shi Bingyin
- Shibasaki Taro
- Shibata Hirotaka
- Shinoda Junji
- Shu Daniel
- Siebert Heidi
- Sigal Helena
- Silva Ana
- Silva Gil
- Simon Judit
- Sinha Arjun
- Skokowska Ewa
- Smelser James
- Smirnov Ivan
- Smith Mark
- Smolyarchuk Elena
- Smuts Nine
- Sobajima Hiroshi
- Soe Kyaw
- Sokolova Liubov
- Solache Ortiz Gustavo
- Soln\uf8r Leidulv
- Solomon Richard
- Solovev Oleg
- Soroka Eugene
- Sosovec Dalibor
- Soto Alfonso
- Soufer Joseph
- Sourij Harald
- Soveri Inga
- Spaak Jonas
- Speeckaert Marijn
- Spodniakova Denisa
- Sritara Piyamitr
- Stanchev Pavel
- Stankiewicz Andrzej
- Stas Koen
- Steele Andrew
- Stefan D Anker
- Stefanidis Ioannis
- Stemler Lutz
- Stephenson Hugo
- Stompor Tomasz
- Stoyanovska-Elencheva Bilyana
- Strack Georg
- Strand Jorma
- Strey Christopher
- Strongin Leonid
- Stryzhak Vasyl
- Su Qing
- Suarez Rosa
- Subramanian Bala
- Sue Kirkman M
- Sugitatsu Kazuya
- Sugiura Toshiyuki
- Sugiyama Toru
- Sulosaari Sakari
- Sun Zhuxing
- Suranyi Michael
- Suzuki Daisuke
- Suzuki Masaaki
- Swift Pauline
- Szerlip Harold
- Szilagyi Iosif
- Szocs Albert
- T Luik P
- T\ue4schner Heidrun
- Tagarev Zhivko
- Tamirisa Aparna
- Tanaka Asami
- Tanaka Seiichi
- Tang Shuifu
- Tanque Maribel
- Tarng Der-Cherng
- Tavli Talat
- Tayob Mohammed
- Teitelbaum Ivor
- Tellier Guy
- Temelkova-Kurktschieva Theodora
- Temizhan Ahmet
- Tengmark Bengt-Olov
- Tennankore Karthik
- Terront M\uf3nica
- Thomson Stephen
- Thorup Frode
- Tigen Mustafa
- Tirador Louie
- Tiuryn-Petrulewicz Agnieszka
- Tobe Sheldon
- Tomanek Pavel
- Tong Nanwei
- Tonolo Giancarlo
- Topliss Duncan
- Toursarkissian Nicole
- Tran Tuan-Huy
- Treger Richard
- Trevisan Roberto
- Trokis J
- Troya Maribel
- Trujillo Freddy
- Trullenque Gretel
- Tsch\uf6pe Diethelm
- Tsoukas George
- Tsunematsu Izumi
- Tu Shih-Te
- Turcu Liana
- Turk Thomas
- Tytus Richard
- Ujihara Makoto
- Ukhanova Olga
- Ulmer Achim
- Umpierrez Guillermo
- Urbach Daniel
- Urbach Dorothea
- Urbanaviciene Egle
- Urbonas Gediminas
- Urina Miguel
- Ustundag Sedat
- Vacaru Georgeta
- Valdes Martin
- Valdez Ortiz Rafael
- Valika Shujauddin
- Vallejos Augusto
- van Buren M
- van den Born Bert-Jan
- van der Giet Markus
- VAN Gaal Luc
- VAN Hoang Lam
- van Zyl Louis
- Vanbelleghem Hilde
- Vandeleur James
- Varleta Paola
- Vasas Szilard
- Vasconcellos Eduardo
- Vasileva Svetla
- Vega Damaris
- Velaviciene Audrone
- Vencio Sergio
- Verges Bruno
- Verlan Nadezhda
- Vi\uf1es Gloria
- Vijayaraman Arutchelvam
- Vila Lobos Ana
- Villagordoa Mesa Juan
- Villegas Iv\ue1n
- Vitou Louise
- Vlad Adrian
- Vlasenko Maryna
- Vorokhobina Natalya
- Wainstein Julio
- Wainstein Julio
- Walsh Michael
- Wan Ronald Ma Ching
- Wang Hao
- Wang Jianqin
- Wang Li
- Wang Lihua
- Wang Xinjun
- Wanner Christoph
- Wasilewska Katarzyna
- Wassermann Alfredo
- Wei Jiali
- Weisnagel Stanley
- Weissman Peter
- Whaley-Connell Adam
- Wierusz-Wysocka Bogna
- Wilderman Igor
- Winston Jonathan
- Wise Jonathan
- Wittert Gary
- Wnetrzak-Michalska Renata
- Wong Yuk-Ki
- Wu Chaoqing
- Wu Mai-Szu
- Wu Ming-Ju
- Wu Tianfeng
- Wudi Krisztina
- Wuerzner Gregoire
- Wynne Katie-Jane
- Xing Changying
- Xiong Fei
- Xu Ning
- Xu Xudong
- Yagil Yoram
- Yajima Ken
- Yakhontov Davyd
- Yale Jean-Francois
- Yamada Daishiro
- Yamada Masayo
- Yamagata Kazuo
- Yamakawa Fumiko
- Yamakawa Ken
- Yamasaki Yoshimitsu
- Yambe Yuko
- Yanai Hidekatsu
- Yang Jinkui
- Yasuda Tetsuyuki
- Yenicerioglu Yavuz
- Yeung Vincent
- Yilmaz Huseyin
- Yin Aiping
- Yoncheva-Mihaylova Mariana
- Young Park Cheol
- Yuan Lee Li
- Yupanqui Hern\ue1n
- Yuryev Michael
- Zakharova Elena
- Zalevskaya Alsu
- Zanozina Olga
- Zaoui Philippe
- Zeig Steven
- Zeng Longyi
- Zhang Hao
- Zhang Yanlin
- Zhang Ying
- Zhao Zhiquan
- Zhdanova Elena
- Zheng Hongguang
- Zhong Ling
- Zhong Liyong
- Zhu Dalong
- Zhukova Larisa
- Zilahi Zsolt
- Zsom Marianna
- Zukermann Robert
- Zykova Tatyana
- Publication venue
- 'S. Karger AG'
- Publication date
- 01/01/2019
- Field of study
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
Role of RET and PHOX2B gene polymorphisms in risk of Hirschsprung's disease in Chinese population
- Author
- Publication venue
- BMJ Group
- Publication date
- Field of study
Reduced RET expression in gut tissue of individuals carrying risk alleles of Hirschsprung's disease
- Author
- Amiel
- Angrist
- Attie
- Barrett
- Borrego
- Brooks
- Burzynski
- Burzynski
- Edery
- Elly Sau-Wai Ngan
- Emison
- Fernandez
- Fitze
- Fitze
- Garcia-Barcelo
- Garcia-Barcelo
- Garcia-Barcelo
- Garcia-Barcelo
- Griseri
- Griseri
- Heanue
- Kenneth Kak-Yuen Wong
- Man-Ting So
- Mercè Garcia-Barceló
- Miao
- Paul Kwong-Hang Tam
- Pelet
- Plaza-Menacho
- Romeo
- Sancandi
- Seri
- Stephens
- Stephens
- Svensson
- Tam
- Thomas Yuk-Yu Leon
- Uesaka
- Veiga-Fernandes
- Vincent Chi-Hang Lui
- Xiaoping Miao
- Yan Chen
- Zheng-Wei Yuan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- Field of study
Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome
- Author
- Abbas Jalal
- Abbate Antonio
- Abdullakutty Jabir
- Abhyanakar Atul D.
- Aboyans Victor
- Abrantes Jose Antonio M.
- Abu-Fadel Mazen
- Acevedo Monica
- Adamkova Vera
- Adhyapak Srilakshmi
- Agarwal Himanshu
- Aggarwal Rahul
- Aggarwal Rajesh K.
- Aguirre Arnoldo
- Ahmed Hinan
- Ahremark Ulf
- Ahuad Guerrero Rodolfo A.
- Aidar Ayoub Jose Carlos
- Airaksinen Juhani K.
- Aitken Denise
- Akatova Evgenia
- Akhter Faiq
- Ako Junya
- Akright Laura
- Akyea-Djamson Ayim
- Al Joundi Tammam
- Al-Windy Nadea Y. Y.
- Alan David
- Alcocer Gamba Marco Antonio
- Alexander John H.
- Alexander Karen
- Alexandru Tom M.
- Alings Marco
- Alonso Martin Joaquin J.
- Alvarisqueta Andres F.
- Alves De Lima Alberto E.
- Amarasekera Stanley
- Amarasena Naomali
- Amir Offer
- Amlani Mohamadali
- Amosova Ekaterina
- Amuchastegui Marcos
- Andersen Kjell
- Andersen Rolf
- Anderson Jay
- Ando Kenji
- Angel Hominal Miguel
- Annam Sharath
- Anscombe Russell
- Apostolovic Svetlana R.
- Appel Karl-Friedrich
- Arandjelovic Aleksandra
- Araneda Guillermo
- Arango Benecke Juan L.
- Arbel Yaron
- Arif Imran
- Armaganijan Luciana
- Arroyo Julian A. Coronel
- Arstall Margaret A.
- Asanin Milika R.
- Atar Shaul
- Athyros Vasilios
- Auguadro Carla
- Ayala Carlos A. Chavez
- Aylward Philip E.
- Azizad Masoud M.
- Bagai Akshay
- Bagriy Andriy
- Bahit Maria Cecilia
- Bai Feng
- Balaguer Recena Javier
- Baldari Duccio
- Balinovac Jovan
- Ball Eric
- Bang Lia E.
- Banuru Sridhar
- Barakovic Fahir
- Baranov Evgeny
- Baranova Elena
- Barbarash Olga L.
- Barbato Emanuele
- Barna Olga M.
- Barone-Rochette Gilles
- Barr Craig
- Barrucco Robert
- Bartels Gerard L.
- Bashir Riyaz
- Bastos Jose Mesquita
- Bata Iqbal
- Batushkin Valeriy
- Bayat Junaid
- Bayram Llamas Edmundo Alfredo
- Bayron Carlos
- Beauloye Christophe
- Bednarski Janusz
- Behrens Steffen
- Belhassane Abdelkader
- Benedicto Amparo
- Bengus Cristina M.
- Benov Haralambi O.
- Berger Rudolf
- Berglund Stefan
- Berk Martin
- Berland Jacques
- Berli Mario A.
- Berlowitz Michael
- Berman Brett
- Bernan Alisa
- Berti Sergio
- Bhagwat Ajit
- Bhagwat Ravi
- Bhansali Prasant
- Bhatt Deepak L.
- Binder Ronald
- Birchem Jessica
- Bittner Vera A.
- Blicharski Tomasz
- Blok Thomas
- Blumberg Eduardo D. S.
- Boccara Franck
- Bodanese Luiz C.
- Bodi Peris Vicente
- Boecker Dirk
- Bojovski Stojko
- Bokarev Igor
- Bokern Marcel J. J. A.
- Bonfanti Alberto J. Cadena
- Bono Julio O. E.
- Bordonava Anselmo P.
- Borse Rohidas
- Bortnick Anna
- Bos Robert J.
- Botas Rodriguez Javier
- Botelho Ana
- Botelho Roberto V.
- Botia Diana C. Luna
- Bottcher Morten
- Bourgeois Ronald
- Brabham David
- Braganza Denise
- Braun-Dullaeus Ruediger
- Breedveld Robert W.
- Brennan J. Matthew
- Brodison Adrian
- Bronzwaer Patrick N. A.
- Brueren Bart R. G.
- Bruguera Cortada Jordi
- Budaj Andrzej
- Bugan Viliam
- Busmane Arija
- Bustamante Labarta Miguel H.
- Busz-Papiez Benita
- Butler Rob
- Bystryk Leszek
- Caccavo Alberto
- Caime Guillermo D.
- Calabro Paolo
- Camprubi Potau Mercedes
- Camsari Ahmet
- Caraco Yoseph
- Carey Charles
- Carlson Eric
- Carnero Gabriela S.
- Carranza Madrigal Jaime
- Carrillo Calvillo Jorge
- Carroll Patrick A.
- Cartasegna Luis R.
- Carter Luther
- Caruso Orlando C.
- Cassimjee Soraya
- Castadot Marc
- Cavallini Claudio
- Cequier Fillat Angel R.
- Cerqueira Maria Jose A. G.
- Cestari Horacio G.
- Cevc Matija
- Cha James
- Chae In-Ho
- Chaitman Bernard
- Chalavarya Gopal
- Chaleff Fred
- Chambilla Jesus M. Carrion
- Chandna Harish
- Chane Majed
- Chang Mark
- Chaudhary Sanjeev
- Chavez V-ctor E. Rodriguez
- Chen Dandan
- Chen Jiyan
- Chen Yundai
- Cheng Shi-Chi
- Cheng Xiaoshu
- Chiang Chern-En
- Chizhov Petr
- Chopda Manoj
- Chopra Vijay K.
- Christenson Stuart
- Chu Alan
- Chua Terrance
- Chumakova Galina
- Chumburidze Vakhtang
- Civeira Murillo Fernando
- Claeys Marc
- Claxton Edmund, Jr.
- Clemmensen Peter
- Clerc Jerome
- Cleveland David
- Clifford Piers
- Clifton Shaun
- Coching Raul Martin
- Codutti Oscar R.
- Cohen Steven
- Collins Nicholas
- Colombo Hugo R.
- Colquhoun David
- Commerford Patrick J.
- Concha Yudy M. Roldan
- Conrad Gary
- Constantine Godwin
- Constantinescu Mircea C. A.
- Convens Carl
- Cools Frank
- Corbett Clive
- Cornel Jan H.
- Correa Flores Roger M.
- Cosavalente Luis A. Camacho
- Cosin Sales Juan
- Costa Fernando
- Coste Pierre
- Cottin Yves
- Coufal Zdenek
- Coverdale Steven G. M.
- Cristian Gabriel
- Cruz Fernandez Jose M.
- Cuccia Claudio
- Cui Lan
- Cyster Henry P.
- Czerski Tomasz
- D'Urso Michael
- Daboul Nizar
- Dagher Georges
- Dahl Charles
- Dai Kazuoki
- Dalby Anthony J.
- Danchin Nicolas
- Dandillaya Ramprasad
- Daniels Christopher
- Das Srihari
- Davidovic Goran
- Davidsen Flemming
- Davies Richard
- Davis William
- de Basson Matthys M. V.
- De Berrazueta Fernandez Jose R.
- De Cesare Nicoletta B.
- De Leo Alessandro
- De Luca Giuseppe
- De Mora Martin Manuel
- De Pellegrin Annamaria
- De Salazar Dora I. Molina
- de Santos Mayler O. N.
- de Silva H. Asita
- de Silva Pedro G. M. B.
- de Souza Juliana A.
- De Wolf Luc
- Delarche Nicolas
- Deloatch Shalonda
- Demirtas Mustafa
- Denham Douglas
- Devarapalli Sai K.
- DeVore Adam D.
- Diamantis Steve
- Diaz Fernandez Jose Francisco
- Diaz Ariel
- Diaz Rafael
- Dickey Sheila
- Dilic Mirza
- Dimkovic Sinisa
- Dimov Bojidar I.
- Dincic Dragan V.
- Ding Chunhua
- Dion Danielle
- Dodds George, III
- Dodic Slobodan
- Dombrowski Keith
- Doncovska Snezana
- Dong Shaohong
- Dong Yugang
- Dorobantu Maria
- Dorsel Thomas
- Dran Ricardo D.
- Drexel Heinz
- Drzewiecka Anna
- Ducas John
- Ducrocq Gregory
- Duda Norberto
- Dujardin Karl
- Dukat Andrej
- Dulak Elzbieta
- Dupuis Robert
- Durak-Nalbantic Azra
- Duronto Ernesto A.
- Dzupina Andrej
- Dzyak Georgiy
- Eagerton Donald
- Eapen Zubin
- East Cara
- Eaton Charles
- Ebrahim Iftikhar O.
- Edelberg Jay M.
- Edes Istvan
- Egorova Liudmila
- Eisenberg Steven
- Ekanayaka Ruvan
- El Shahawy Mahfouz
- El-Ahdab Fadi
- Elias Mazen
- Eliaschewitz Freddy G.
- Elliott John
- Endsley Patricia
- Eppinger Arleen
- Erglis Andrejs
- Ersanli Murat
- Fadlallah Hussein
- Faes Dirk
- Faggiano Pompilio
- Fairlamb James
- Fajardo Campos Pedro
- Falukozy Jozsef
- Fang Chih-Yuan
- Fang Weiyi
- Fanghanel Salmon Guillermo
- Farhat Naim
- Farrar Michael
- Fausto Ovando Sergio R.
- Fazekas Frantisek
- Fazlibegovic Emir
- Feitosa Gilson S.
- Fell David
- Feng Yi
- Fernandes Manenti Euler Roberto F.
- Fernandez Portales Javier
- Fernandez Angela M.
- Fernandez Mauricio
- Fernando Nimali
- Ferrari Emile
- Ferratini Maurizio
- Ferrolino Arthur
- Filardi Pasquale Perrone
- Fischer Stuart
- Fishberg Robert
- Fisher Daniel
- Fisher Nicholas
- Fisher Raewyn
- Florenzano Fernando
- Flores Enrique
- Flores Romulo E. Oqueli
- Fong Peter
- Forgosh Les
- Foster Malcolm
- Foster Robert
- Francis Adi
- Franek Edward
- Fras Zlatko
- French William J.
- Friedman Dennis
- Frost Lars
- Fu Guosheng
- Fuchs Shmuel
- Fuentes Jimenez Francisco
- Fujii Kenshi
- Fujimoto Kazuteru
- Fujinaga Hiroyuki
- Fulop Peter
- Fulwani Mahesh C.
- Furukawa Yutaka
- Galski Thomas
- Galvani Marcello
- Gapon Liudmila
- Garcia Brasca Daniela F.
- Garcia Castillo Armando
- Garcia Duran Ruben O.
- Garcia Lledo Jose Alberto
- Garcia-Dorado David
- Gardner Geraldine
- Garrahy Paul J.
- Garrido Marcelo
- Garza Ruiz Jose Angel
- Gavish Dov
- Ge Junbo
- Gelormini Joseph
- Gerber Jaime
- Gerber Robert
- Ghitis Arnold
- Ghlonti Ramaz
- Gibson Paul
- Gielen Stephan
- Giesler Gregory
- Gil-Extremera Blas
- Gilbert John M.
- Gillespie Eve
- Gilmore Richard
- Gimple Lawrence
- Giordano Jorge A.
- Giorgeto Flavio E.
- Gislason Gunnar
- Giuliano Maria E.
- Gniot Jacek
- Goch Aleksander
- Goloborodko Borys
- Gomez Vilamajo Oscar A.
- Gonsorcik Jozef
- Gonzales Rolando J. Vargas
- Gonzalez Diaz Belinda
- Gonzalez Salas Luis Gerardo
- Gonzalez-Juanatey Carlos
- Gonzalez-Juanatey Jose R.
- Goodman Shaun G.
- Gordeev Ivan
- Gordienko Alexander
- Gorny Jerzy
- Gosselin Gilbert
- Gosselink Antonius T. M.
- Gotcheva Nina N.
- Govinda Ravishankar A.
- Goyal Naresh K.
- Gremmler Uwe
- Grewal Jasprakash Singh
- Griffiths Huw
- Gring Christian
- Groenemeijer Bjorn E.
- Groutars Reginald G. E. J.
- Guardigli Gabriele
- Guerrero De Leon Maria
- Guha Santanu
- Gullestad Lars
- Guneri Sema
- Guo Ying
- Gurevich Victor
- Gusi Tragant Gabriel
- Guzman Pablo N.
- Haddad Tariq
- Hagstrom Emil
- Hahalis P. I. Georgios
- Halabi Majdi
- Halcox Julian
- Hald Flemming
- Haldis Thomas
- Hall Jason
- Halvorsen Sigrun
- Hameed Adnan
- Haniffa Ruvaiz
- Hanotin Corinne
- Hansen Ole
- Haraguchi Takuya
- Harding Scott
- Harkut Pankaj
- Harrington Robert A.
- Harris Barry
- Harris Bill
- Hart Hamish
- Hata Yoshiki
- Hattler Brack
- Hedman Anu
- Heidenreich Lothar
- Heinc Petr
- Heitzer Thomas
- Hemetsberger Rayyan
- Henderson David
- Henkin Yaakov
- Herath Jagath I.
- Herazo Aristides Sotomayor
- Hermans Kurt
- Hermans Walter R. M.
- Hernandez Henry A. Anchante
- Herrman Johannes P. R.
- Hersbach Ferry M. R. J.
- Herzog William, Jr.
- Hess Connie Ng
- Higashikata Toshinori
- Higuera Juan Diego
- Hii Chris L. S.
- Hirayama Atsushi
- Hirooka Keiji
- Hlatky Mark A.
- Hoag Gordon
- Hodes Zachary
- Hoffer Etienne
- Hoffman David
- Hong Taekjong
- Hoogslag Pieter A. M.
- Hoppe Uta
- Horak David
- Horowitz John
- Horvath Ivan
- Horwitz Phillip
- Hove Jens D.
- Hrabar Adrian D.
- Hranai Marian
- Hsieh I-Chang
- Huang Lan
- Huang Shi'An
- Huang Tsuei-Yuan
- Huang Weijian
- Huber Kurt
- Huidobro Laura
- Huikuri Heikki
- Hunter John
- Hurtig Ulf
- Hussein Osamah
- Huynh Thao
- Hwang Juey-Jen
- Ilic Stevan
- Ilieva-Pandeva Katya A.
- Ince Carlos
- Iniguez Andres
- Iqbal Syed M. R.
- Irimpen Anand
- Istratoaie Octavian
- Ito Kashima
- Ivanov Igor G.
- Ivanova Raya
- Ivanovic Nikola
- Iyengar Shamanna S.
- Izzo Mark
- Jacoby Douglas
- Jafar Zubair
- Jaffrani Naseem
- Jain Diwakar
- Janik Matthew
- Janosik Denise
- Jaramillo Nicolas
- Jatin Fernando G. Manzur
- Jaworska Krystyna
- Jayawardena Jayanthimala
- Jensen Steen Agergaard
- Jeong Myung Ho
- Jeppesen Jorgen
- Jeserich Michael
- Jiang Weihong
- Jintapakorn Woravut
- Johansen Peter Betton
- Jonas Michael
- Jones William Schuyler
- Jordan Joseph Dedrick
- Jortveit Jarle
- Joshi Abhijeet B.
- Joshi Parag
- Jovin Ion
- Jujjuru Srimannarayana
- Jukema J. Wouter
- Juonala Markus
- Jure Horacio O.
- Jurgaitiene Ruta
- Kadr Honer
- Kaewsuwanna Pinij
- Kahali Dhiman
- Kaikkonen Kari
- Kaiser Sergio
- Kalashetti Suhas
- Kalil Renato
- Kamensky Gabriel
- Kamiya Haruo
- Kandasamy Balachandran
- Kapin Tibor
- Kaplan Refik
- Kapp Ilse E.
- Karalis Ioannis
- Karlsberg Ronald
- Karna Sunil
- Karpenko Oleksandr
- Karpenko Yuriy
- Karpov Yuri
- Karpov Yuriy
- Kartalis Athanasios
- Kasim Sazzli
- Katona Andras
- Katsuda Yousuke
- Katz Amos
- Kaucak Vladimir
- Kavaliauskiene Roma
- Kawasaki Tomohiro
- Ke Yuannan
- Keating Friederike
- Kedev Sasko
- Keen William
- Kehasukcharoen Wirash
- Kelsey Sheryl F.
- Kerkar Prafulla
- Khabeishvili George
- Khaira Ajit S.
- Khaisheva Larisa
- Khan Abul
- Khan Aziz
- Khan Misal
- Khasanov Niiaz
- Khintibidze Irakli
- Khurana Sandeep
- Kibarskis Aleksandras
- Kichukov Kostadin N.
- Killat Holger
- Kim Chongjin
- Kim Hyo Soo
- Kim Moo Hyun
- Kim Sang-Hyun
- Kimmelstiel Carey
- Kimura Kazuo
- Kimura Takeshi
- King Marilyn
- Kinzfogl George, III
- Kirma Cevat
- Kishi Koichi
- Kiss Robert Gabor
- Kiviniemi Tuomas
- Kjovkaroski Aleksandar
- Klancke Kim
- Klantsa Andriy
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- Subkovas Eduardas
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- Turk Samir
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- van Diepen Sean F. P.
- Van Huysduynen-Monraats Pascalle S. Hooft
- Van Zyl Louis J.
- Vardi Gil
- Varleta Paola
- Vatutin Mykola
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- Velcheva Elena S.
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- Vered Zvi
- Vervoort Geert
- Vico Marisa L.
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- Vidotti Maria H.
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- Viergever Eric P.
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- Vijay Nampalli
- Vijayaraghavan Ram
- Vikman Saila
- Viktorova Inna
- Violini Roberto
- Vishnevsky Alexander Y.
- Vizel Saul
- Vo Anthony
- Voeller Heinz
- Voevoda Mikhail I.
- Vogel Robert
- Vohra Rakesh
- Vora Kishor
- Voyce Stephen
- Vrolix Mathias C. M.
- Vulic Dusko
- Vuurmans Tycho
- Wada Atsuyuki
- Waider Winfried
- Waisman Gabriel D.
- Waites Jonathon H.
- Wali Andreas
- Walichiewicz Piotr Maria
- Waltenberger Johannes
- Waltman Jonathan
- Wang Jian'An
- Wang Jianzhong
- Wang Jingfeng
- Wattanakit Keattiyoat
- Wei Meng
- Weidinger Franz
- Weil Joachim
- Weintraub Howard
- Weissbrodt Matthias
- Welka Stephen
- Welker James
- Wells Terry
- Werner Nikos
- Westerhausen Donald, Jr.
- Whitaker Jack
- White Harvey D.
- White Lindsey
- White Matthew
- Wiersma Jacobijne J.
- Wilkins Gerard
- Wilkinson Peter
- Willems Frank F.
- Wilson Matthew D.
- Winkelmann Bernhard
- Wiseman Alan
- Witt Nils
- Wlodarczak Adrian
- Wojewoda Pawel
- Wollaert Bart
- Wong Yuk-Ki
- Wongpraparut Nattawut
- Worner Diz Fernando
- Wright Scott
- Xatzitolios Apostolos
- Xavier Denis
- Xenakis Mark
- Xu Biao
- Xu Dingli
- Xu Xiping
- Yagensky Andriy
- Yakushin Sergey
- Yan Andrew Tze-Kay
- Yan Bryan P. Y.
- Yanez Mario
- Yang Eric
- Yang Xiangjun
- Yang Xinchun
- Yao Zhuhua
- Yazdani Shahram
- Yerra Shiv Kumar
- Yin Wei-Hsian
- Yong Huo
- Yoon Jung Han
- Younis Liwa
- Yu Yihua
- Yuan Zuyi
- Yusoff Khalid
- Zahger Doron
- Zaidman Cesar J.
- Zainea Mark
- Zaman Azfar
- Zeiher Andreas M.
- Zhang Wenwu
- Zhang Xuelian
- Zhang Zheng
- Zhao Xingsheng
- Zheng Yang
- Zheng Zeqi
- Zhou Yujie
- Zhu Hong
- Zirlik Andreas
- Zizka Jiri
- Zong Wenxia
- Zrazhevsky Konstantin
- Zuniga Jose D. Hernandez
- Zurakowski Aleksander
- Zuran Ivan
- Zweiker Robert
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Alirocumab and cardiovascular outcomes after acute coronary syndrome
- Author
- Abbas Jalal
- Abbate Antonio
- Abdullakutty Jabir
- Abhyanakar Atul D.
- Aboyans Victor
- Abrantes Jose Antonio M.
- Abu-Fadel Mazen
- Acevedo Monica
- Adamkova Vera
- Adhyapak Srilakshmi
- Agarwal Himanshu
- Aggarwal Rahul
- Aggarwal Rajesh K.
- Aguirre Arnoldo
- Ahmed Hinan
- Ahremark Ulf
- Ahuad Guerrero Rodolfo A.
- Aidar Ayoub Jose Carlos
- Airaksinen Juhani K.
- Aitken Denise
- Akatova Evgenia
- Akhter Faiq
- Ako Junya
- Akright Laura
- Akyea-Djamson Ayim
- Al Joundi Tammam
- Al-Windy Nadea Y. Y.
- Alan David
- Alcocer Gamba Marco Antonio
- Alexander John H.
- Alexander Karen
- Alexandru Tom M.
- Alings Marco
- Alonso Martin Joaquin J.
- Alvarisqueta Andres F.
- Alves De Lima Alberto E.
- Amarasekera Stanley
- Amarasena Naomali
- Amir Offer
- Amlani Mohamadali
- Amosova Ekaterina
- Amuchastegui Marcos
- Andersen Kjell
- Andersen Rolf
- Anderson Jay
- Ando Kenji
- Angel Hominal Miguel
- Annam Sharath
- Anscombe Russell
- Apostolovic Svetlana R.
- Appel Karl-Friedrich
- Arandjelovic Aleksandra
- Araneda Guillermo
- Arango Benecke Juan L.
- Arbel Yaron
- Arif Imran
- Armaganijan Luciana
- Arroyo Julian A. Coronel
- Arstall Margaret A.
- Asanin Milika R.
- Atar Shaul
- Athyros Vasilios
- Auguadro Carla
- Ayala Carlos A. Chavez
- Aylward Philip E.
- Azizad Masoud M.
- Bagai Akshay
- Bagriy Andriy
- Bahit Maria Cecilia
- Bai Feng
- Balaguer Recena Javier
- Baldari Duccio
- Balinovac Jovan
- Ball Eric
- Bang Lia E.
- Banuru Sridhar
- Barakovic Fahir
- Baranov Evgeny
- Baranova Elena
- Barbarash Olga L.
- Barbato Emanuele
- Barna Olga M.
- Barone-Rochette Gilles
- Barr Craig
- Barrucco Robert
- Bartels Gerard L.
- Bashir Riyaz
- Basson Matthys M. de V.
- Bastos Jose Mesquita
- Bata Iqbal
- Batushkin Valeriy
- Bayat Junaid
- Bayram Llamas Edmundo Alfredo
- Bayron Carlos
- Beauloye Christophe
- Bednarski Janusz
- Behrens Steffen
- Belhassane Abdelkader
- Benedicto Amparo
- Bengus Cristina M.
- Benov Haralambi O.
- Berger Rudolf
- Berglund Stefan
- Berk Martin
- Berland Jacques
- Berli Mario A.
- Berlowitz Michael
- Berman Brett
- Bernan Alisa
- Berti Sergio
- Bhagwat Ajit
- Bhagwat Ravi
- Bhansali Prasant
- Bhatt D. L.
- Binder Ronald
- Birchem Jessica
- Bittner V. A.
- Blicharski Tomasz
- Blok Thomas
- Blumberg Eduardo D. S.
- Boccara Franck
- Bodanese Luiz C.
- Bodi Peris Vicente
- Boecker Dirk
- Bojovski Stojko
- Bokarev Igor
- Bokern Marcel J. J. A.
- Bonfanti Alberto J. Cadena
- Bono Julio O. E.
- Bordonava Anselmo P.
- Borse Rohidas
- Bortnick Anna
- Bos Robert J.
- Botas Rodriguez Javier
- Botelho Ana
- Botelho Roberto V.
- Botia Diana C. Luna
- Bottcher Morten
- Bourgeois Ronald
- Brabham David
- Braganza Denise
- Braun-Dullaeus Ruediger
- Breedveld Robert W.
- Brennan J. Matthew
- Brodison Adrian
- Bronzwaer Patrick N. A.
- Brueren Bart R. G.
- Bruguera Cortada Jordi
- Budaj Andrzej
- Bugan Viliam
- Busmane Arija
- Bustamante Labarta Miguel H.
- Busz-Papiez Benita
- Butler Rob
- Bystryk Leszek
- Caccavo Alberto
- Caime Guillermo D.
- Calabro Paolo
- Camprubi Potau Mercedes
- Camsari Ahmet
- Caraco Yoseph
- Carey Charles
- Carlson Eric
- Carnero Gabriela S.
- Carranza Madrigal Jaime
- Carrillo Calvillo Jorge
- Carroll Patrick A.
- Cartasegna Luis R.
- Carter Luther
- Caruso Orlando C.
- Cassimjee Soraya
- Castadot Marc
- Cavallini Claudio
- Cequier Fillat Angel R.
- Cerqueira Maria Jose A. G.
- Cestari Horacio G.
- Cevc Matija
- Cha James
- Chae In-Ho
- Chaitman Bernard
- Chalavarya Gopal
- Chaleff Fred
- Chambilla Jesus M. Carrion
- Chandna Harish
- Chane Majed
- Chang Mark
- Chaudhary Sanjeev
- Chavez Victor E. Rodriguez
- Chen Dandan
- Chen Jiyan
- Chen Yundai
- Cheng Shi-Chi
- Cheng Xiaoshu
- Chiang Chern-En
- Chiang Chern-En
- Chizhov Petr
- Chopda Manoj
- Chopra Vijay K.
- Christenson Stuart
- Chu Alan
- Chua Terrance
- Chumakova Galina
- Chumburidze Vakhtang
- Civeira Murillo Fernando
- Claeys Marc
- Claxton Edmund
- Clemmensen Peter
- Clerc Jerome
- Cleveland David
- Clifford Piers
- Clifton Shaun
- Coching Raul Martin
- Codutti Oscar R.
- Cohen Steven
- Collins Nicholas
- Colombo Hugo R.
- Colquhoun David
- Commerford Patrick J.
- Concha Yudy M. Roldan
- Conrad Gary
- Constantine Godwin
- Constantinescu Mircea C. A.
- Convens Carl
- Cools Frank
- Corbett Clive
- Cornel Jan H.
- Correa Flores Roger M.
- Cosavalente Luis A. Camacho
- Cosin Sales Juan
- Costa Fernando
- Coste Pierre
- Cottin Yves
- Coufal Zdenek
- Coverdale Steven G. M.
- Cristian Gabriel
- Cruz Fernandez Jose M.
- Cuccia Claudio
- Cui Lan
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- Dahl Charles
- Dai Kazuoki
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- Dandillaya Ramprasad
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- Davidovic Goran
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- De Cesare Nicoletta B.
- De Leo Alessandro
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- Diaz Fernandez Jose Francisco
- Diaz Ariel
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- Dilic Mirza
- Dimkovic Sinisa
- Dimov Bojidar I.
- Dincic Dragan V.
- Ding Chunhua
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- Dodds George
- Dodic Slobodan
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- Doncovska Snezana
- Dong Shaohong
- Dong Yugang
- Dorobantu Maria
- Dorsel Thomas
- Dran Ricardo D.
- Drexel Heinz
- Drzewiecka Anna
- Ducas John
- Ducrocq Gregory
- Duda Norberto
- Dujardin Karl
- Dukat Andrej
- Dulak Elzbieta
- Dupuis Robert
- Durak-Nalbantic Azra
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- Egorova Liudmila
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- Ekanayaka Ruvan
- El Shahawy Mahfouz
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- Elliott John
- Endsley Patricia
- Eppinger Arleen
- Erglis Andrejs
- Ersanli Murat
- Fadlallah Hussein
- Faes Dirk
- Faggiano Pompilio
- Fairlamb James
- Fajardo Campos Pedro
- Falukozy Jozsef
- Fang Chih-Yuan
- Fang Weiyi
- Fanghanel Salmon Guillermo
- Farhat Naim
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- Fausto Ovando Sergio R.
- Fazekas Frantisek
- Fazlibegovic Emir
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- Fernandez Angela M.
- Fernandez Mauricio
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- Ferrari Emile
- Ferratini Maurizio
- Ferrolino Arthur
- Filardi Pasquale Perrone
- Fischer Stuart
- Fishberg Robert
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- Fisher Raewyn
- Florenzano Fernando
- Flores Enrique
- Flores Romulo E. Oqueli
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- Forgosh Les
- Foster Malcolm
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- Franek Edward
- Fras Zlatko
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- Hagstrom Emil
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- Halabi Majdi
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- Huang Tsuei-Yuan
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- Kinzfogl George
- Kirma Cevat
- Kishi Koichi
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- Soonfuang Wasant
- Soopold sllar
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- Soran Handrean
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- Sousa Luciano
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- Strelnieks Aldis
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- Stryuk Raisa
- Su Guohai
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- Sugino Hiroshi
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- Sukonthasarn Apichard
- Suligoj Natasa Cernic
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- Tissera Nirmali
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- Triana Miguel A. Urina
- Tricoci P.
- Troquay Roland P. Th
- Trotter Charlene
- Tsai Wei-Chuan
- Tse Hung-Fat
- Tseluyko Vira
- Tumbev Haralin S.
- Tunon Fernandez Jose
- Tunon Jose
- Turgeman Yoav
- Turi Tibor
- Turk Samir
- Tyrenko Vadim V.
- Tzekova Maria L.
- Ueda Yasunori
- Uehara Hiroki
- Ueng Kwo-Chang
- Ungi Imre
- Ural Ertan
- Ushakov Olexiy
- Utsu Noriaki
- Vahula Veiko
- Vakaluyk Ihor
- Valgimigli Marco
- Vallejo Gregorio Sanchez
- Vallejos Julio A.
- Van Der Wal Ruud M. A.
- Van Der Zwaan Coenraad C.
- van Diepen Sean F. P.
- Van Huysduynen-Monraats Pascalle S. Hooft
- Van Zyl Louis J.
- Vardi Gil
- Varleta Paola
- Vatutin Mykola
- Vedere Amarnath
- Vejar Margarita
- Velasquez Julio R. Durand
- Velcheva Elena S.
- Verdel Gerardus J. E.
- Vered Zvi
- Vervoort Geert
- Vico Marisa L.
- Vida Manuel
- Videbaek Lars
- Vidotti Maria H.
- Vidovich Mladen
- Viergever Eric P.
- Viigimaa Margus
- Vijay Nampalli
- Vijayaraghavan Ram
- Vikman Saila
- Viktorova Inna
- Violini Roberto
- Vishnevsky Alexander Y.
- Vizel Saul
- Vo Anthony
- Voeller Heinz
- Voevoda Mikhail I.
- Vogel Robert
- Vohra Rakesh
- Vora Kishor
- Voyce Stephen
- Vrolix Mathias C. M.
- Vulic Dusko
- Vuurmans Tycho
- Wada Atsuyuki
- Waider Winfried
- Waisman Gabriel D.
- Waites Jonathon H.
- Wali Andreas
- Walichiewicz Piotr Maria
- Waltenberger Johannes
- Waltman Jonathan
- Wang Jian'An
- Wang Jianzhong
- Wang Jingfeng
- Wattanakit Keattiyoat
- Wei Meng
- Weidinger Franz
- Weil Joachim
- Weintraub Howard
- Weissbrodt Matthias
- Welka Stephen
- Welker James
- Wells Terry
- Werner Nikos
- Westerhausen Donald
- Whitaker Jack
- White H. D.
- White Lindsey
- White Matthew
- Wiersma Jacobijne J.
- Wilkins Gerard
- Wilkinson Peter
- Willems Frank F.
- Wilson Matthew D.
- Winkelmann Bernhard
- Wiseman Alan
- Witt Nils
- Wlodarczak Adrian
- Wojewoda Pawel
- Wollaert Bart
- Wong Yuk-Ki
- Wongpraparut Nattawut
- Worner Diz Fernando
- Wright Scott
- Xatzitolios Apostolos
- Xavier Denis
- Xenakis Mark
- Xu Biao
- Xu Dingli
- Xu Xiping
- Yagensky Andriy
- Yakushin Sergey
- Yan Andrew Tze-Kay
- Yan Bryan P. Y.
- Yanez Mario
- Yang Eric
- Yang Xiangjun
- Yang Xinchun
- Yao Zhuhua
- Yazdani Shahram
- Yerra Shiv Kumar
- Yin Wei-Hsian
- Yong Huo
- Yoon Jung Han
- Younis Liwa
- Yu Yihua
- Yuan Zuyi
- Yusoff Khalid
- Zahger Doron
- Zaidman Cesar J.
- Zainea Mark
- Zaman Azfar
- Zeiher A. M.
- Zhang Wenwu
- Zhang Xuelian
- Zhang Zheng
- Zhao Xingsheng
- Zheng Yang
- Zheng Zeqi
- Zhou Yujie
- Zhu Hong
- Zirlik Andreas
- Zizka Jiri
- Zong Wenxia
- Zrazhevsky Konstantin
- Zuniga Jose D. Hernandez
- Zurakowski Aleksander
- Zuran Ivan
- Zweiker Robert
- Publication venue
- Publication date
- 01/01/2018
- Field of study
BACKGROUN