12 research outputs found
Synthesis and characterization of polypyrrole decorated graphene/Ī²-cyclodextrin composite for low level electrochemical detection of mercury (II) in water
Mercury (Hg(II)) is considered as one of the most toxic element that directly affects the human health and the environment. Therefore, in this study, we propose a sensitive and disposable electrochemical sensor for the detection of Hg(II) in various water samples using polypyrrole (PPy) decorated graphene/-cyclodextrin (GR-CD) composite modified screen-printed carbon electrode (SPCE). The GRCD/PPy composite was synthesized by chemical oxidation of PPy monomer in GR-CD solution using FeCl3. Differential pulse voltammetry (DPV) is used for the detection of Hg(II) and the DPV results reveal that GR-CD/PPy composite modified SPCE has high sensitivity towards Hg(II) than bare, GR, GR-CD and PPy modified SPCEs. The optimization studies such as effect of pH, accumulating time and effect of scanning potential towards the detection of Hg(II) were investigated. The GR-CD/PPy composite modified SPCE could detect the Hg(II) up to 51.56 M Lā1 with the limit of detection (LOD) of 0.47 nM Lā1. The obtained LOD was well below the guideline level of Hg(II) set by the Worldās Health Organization (WHO) and U.S. Environmental Protection Agency (EPA). In addition, the fabricated GR-CD/PPy composite modified SPCE selectively detected the Hg(II) in the presence of potentially interfering metal cations
Recent Advances in Two-Dimensional MXene-Based Electrochemical Biosensors for Sweat Analysis
Sweat, a biofluid secreted naturally from the eccrine glands of the human body, is rich in several electrolytes, metabolites, biomolecules, and even xenobiotics that enter the body through other means. Recent studies indicate a high correlation between the analytesā concentrations in the sweat and the blood, opening up sweat as a medium for disease diagnosis and other general health monitoring applications. However, low concentration of analytes in sweat is a significant limitation, requiring high-performing sensors for this application. Electrochemical sensors, due to their high sensitivity, low cost, and miniaturization, play a crucial role in realizing the potential of sweat as a key sensing medium. MXenes, recently developed anisotropic two-dimensional atomic-layered nanomaterials composed of early transition metal carbides or nitrides, are currently being explored as a material of choice for electrochemical sensors. Their large surface area, tunable electrical properties, excellent mechanical strength, good dispersibility, and biocompatibility make them attractive for bio-electrochemical sensing platforms. This review presents the recent progress made in MXene-based bio-electrochemical sensors such as wearable, implantable, and microfluidic sensors and their applications in disease diagnosis and developing point-of-care sensing platforms. Finally, the paper discusses the challenges and limitations of MXenes as a material of choice in bio-electrochemical sensors and future perspectives on this exciting material for sweat-sensing applications
Efficient photocatalytic degradation of textile dye pollutants using thermally exfoliated graphitic carbon nitride (TEāgāC3N4)
Abstract Graphitic carbon nitride (gāC3N4), an organic photocatalyst was reported to have beneficial properties to be used in wastewater treatment applications. However, gāC3N4, in its bulk form was found to have poor photocatalytic degradation efficiency due to its inherent limitations such as poor specific surface area and fast electronāhole pair recombination rate. In this study, we have tuned the physiochemical properties of bulk gāC3N4 by direct thermal exfoliation (TEāgāC3N4) and examined their photocatalytic degradation efficiency against abundant textile dyes such as methylene blue (MB), methyl orange (MO), and rhodamine B (RhB). The degradation efficiencies for MB, MO, and RhB dyes are 92āĀ±ā0.18%, 93āĀ±ā0.31%, and 95āĀ±ā0.4% respectively in 60Ā min of UV light irradiation. The degradation efficiency increased with an increase in the exfoliation temperature. The prepared catalysts were characterized using FTIR, XRD, FE-SEM, EDAX, BET, and UV-DRS. In BET analysis, TEāgāC3N4 samples showed improved surface area (48.20 m2/g) when compared to the bulk gāC3N4 (5.03 m2/g). Further, the TEāgāC3N4 had 2.98 times higher adsorption efficiency than the bulk ones. The free radicals scavenging studies revealed that the superoxide radicals played an important role in the photodegradation for dyes, when compared to the hydroxyl radical (.OH) and the photo-induced holes (h+), Photoluminescence (PL) emission and electrochemical impedance spectroscopy (EIS) spectra of TEāgāC3N4 indicated a lowered electronāhole pairsā recombination rate and an increased photo-induced charge transfer respectively. Further, the TEāgāC3N4 were found to have excellent stability for up to 5 cycles with only a minor decrease in the activity from 92% to 86.2%. These findings proved that TEāgāC3N4 was an excellent photocatalyst for the removal and degradation of textile dyes from wastewater
Hierarchical 3D Snowflake-like Iron Diselenide: A Robust Electrocatalyst for Furaltadone Detection
An electrocatalyst with a large active site is critical
for the
development of a high-performance electrochemical sensor. This work
demonstrates the fabrication of an iron diselenide (FeSe2)-modified screen-printed carbon electrode (SPCE) for the electrochemical
determination of furaltadone (FLD). It has been prepared by the facile
method and systematically characterized with various microscopic/spectroscopic
approaches. Due to advantageous physiochemical properties, the FeSe2/SPCE showed a low charge-transfer resistance value of 200
Ī© in 5.0 mM [Fe(CN)6]3ā/4ā containing 0.1 M KCl. More importantly, the FeSe2/SPCE
exhibited superior catalytic performance compared to the bare SPCE
for FLD sensing based on the electrochemical response in terms of
a peak potential of ā0.44 V (vs Ag/AgCl (sat.
KCl)) and cathodic response current of ā22.8 Ī¼A. Operating
at optimal conditions, the FeSe2-modified electrode showed
wide linearity from 0.01 to 252.2 Ī¼M with a limit of detection
of 0.002 Ī¼M and sensitivity of 1.15 Ī¼A Ī¼Mā1 cmā2. The analytical performance of the FeSe2-based platform is significantly higher than many previously
reported FLD electrochemical sensors. Furthermore, the FeSe2/SPCE also has a promising platform for FLD detection with high sensitivity,
good selectivity, excellent stability, and robust reproducibility.
Thus, the finding above shows that the FeSe2/SPCE is a
highly suitable candidate for the electrochemical determination of
glucose levels for real-time applications such as in human urine and
river water samples
Boosting the Electrochemical Detection Response Toward Hydroxychloroquine via Tungsten Trioxide Nanorods/Nitrogen-Doped Carbon Nanofiber Nanocomposite
The overusage of hydroxychloroquine (HQ)
amidst the outbreak of
coronavirus disease has contributed to increased fatalities concerning
HQ poisoning. Hence, there is an utmost requirement to develop accurate
and onsite methodologies for monitoring HQ in biological samples and
water bodies. Metal-oxide-decorated carbon nanomaterials present excellent
electrocatalytic properties, contributing to improved sensor responses.
This study introduces tungsten trioxide nanorods/nitrogen-doped carbon
nanofiber (WO3/N-CNF) nanocomposite, capable of detecting
HQ electrochemically. The conjunction of WO3 with N-CNF
offers accelerated charge transfer kinetics with an abundance of surface-active
sites that benefit the sensing mechanism. Furthermore, synergistic
effects arising from the nanocomposite augment the conductivity and
promote faster ion diffusion. The WO3/N-CNF-based electrochemical
sensor deliver high performance in the working concentration range
of 0.007ā480 Ī¼M and provides a detection limit of 2.0
nM for HQ. The fabricated sensor has excellent operational stability
and reproducibility and is also able to show a superb selectivity
toward HQ in comparison to various interfering compounds. This indicates
that the designed WO3/N-CNF nanocomposite can be used as
a potential electrocatalyst for the real-time monitoring of HQ
Zinc Oxide/Phosphorus-Doped Carbon Nitride Composite as Potential Scaffold for Electrochemical Detection of Nitrofurantoin
Herein, we present an electrocatalyst constructed by zinc oxide hexagonal prisms/phosphorus-doped carbon nitride wrinkles (ZnO HPs/P-CN) prepared via a facile sonochemical method towards the detection of nitrofurantoin (NF). The ZnO HPs/P-CN-sensing platform showed amplified response and low-peak potential compared with other electrodes. The exceptional electrochemical performance could be credited to ideal architecture, rapid electron/charge transfer, good conductivity, and abundant active sites in the ZnO HPs/P-CN composite. Resulting from these merits, the ZnO HPs/P-CN-modified electrode delivered rapid response (2 s), a low detection limit (2 nM), good linear range (0.01–111 µM), high sensitivity (4.62 µA µM−1 cm2), better selectivity, decent stability (±97.6%), and reproducibility towards electrochemical detection of NF. We further demonstrated the feasibility of the proposed ZnO HPs/P-CN sensor for detecting NF in samples of water and human urine. All the above features make our proposed ZnO HPs/P-CN sensor a most promising probe for detecting NF in natural samples