Search for pulsating PMS stars in NGC 6383

A search for pulsating pre-main sequence (PMS) stars was performed in the young open cluster NGC 6383 using CCD time series photometry in Johnson B & V filters. With an age of only ~1.7 million years all cluster members later than spectral type A0 have not reached the ZAMS yet, hence being ideal candidates for investigating PMS pulsation among A and F type stars. In total 286 stars have been analyzed using classical Fourier techniques. From about a dozen of stars within the boundaries of the classical instability strip, two stars were found to pulsate: NGC 6383 #170, with five frequencies simultaneously, and NGC 6383 #198, with a single frequency. In addition, NGC 6383 #152 is a suspected PMS variable star, but our data remain inconclusive. Linear, non-adiabatic models assuming PMS evolutionary phase and purely radial pulsation were calculated for the two new PMS pulsators. NGC 6383 #170 appears to pulsate radially in third and fifth overtones, while the other three frequencies seem to be of non-radial nature. NGC 6383 #198 pulsates monoperiodically, most probably in the third radial overtone. Magnitudes and B-V colours were available in the literature for only one third of all stars and we used them for calibrating the remaining.Comment: 12 pages, 11 figures, accepted by MNRA

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

SummaryAtopic dermatitis (AD) is a chronic itch and inflammatory disorder of the skin that affects one in ten people. Patients suffering from severe AD eventually progress to develop asthma and allergic rhinitis, in a process known as the “atopic march.” Signaling between epithelial cells and innate immune cells via the cytokine thymic stromal lymphopoietin (TSLP) is thought to drive AD and the atopic march. Here, we report that epithelial cells directly communicate to cutaneous sensory neurons via TSLP to promote itch. We identify the ORAI1/NFAT calcium signaling pathway as an essential regulator of TSLP release from keratinocytes, the primary epithelial cells of the skin. TSLP then acts directly on a subset of TRPA1-positive sensory neurons to trigger robust itch behaviors. Our results support a model whereby calcium-dependent TSLP release by keratinocytes activates both primary afferent neurons and immune cells to promote inflammatory responses in the skin and airways

SearchCal: a Virtual Observatory tool for searching calibrators in optical long baseline interferometry. I: The bright object case

In long baseline interferometry, the raw fringe contrast must be calibrated to obtain the true visibility and then those observables that can be interpreted in terms of astrophysical parameters. The selection of suitable calibration stars is crucial for obtaining the ultimate precision of interferometric instruments like the VLTI. We have developed software SearchCal that builds an evolutive catalog of stars suitable as calibrators within any given user-defined angular distance and magnitude around the scientific target. We present the first version of SearchCal dedicated to the bright-object case V<=10; K<=5). Star catalogs available at the CDS are consulted via web requests. They provide all the useful information for selecting of calibrators. Missing photometries are computed with an accuracy of 0.1 mag and the missing angular diameters are calculated with a precision better than 10%. For each star the squared visibility is computed by taking the wavelength and the maximum baseline of the foreseen observation into account.} SearchCal is integrated into ASPRO, the interferometric observing preparation software developed by the JMMC, available at the address: http://mariotti.fr

The decay of optical emission from the Gamma-Ray Burst GRB 970228

We present the R_c band light curve of the optical transient (OT) associated with GRB970228, based on re-evaluation of existing photometry. Data obtained until April 1997 suggested a slowing down of the decay of the optical brightness. However, the HST observations in September 1997 show that the light curve of the point source is well represented by a single power law, with a ``dip'', about a week after the burst occured. The exponent of the power law decay is $\alpha$ = --1.10 $\pm$ 0.04. As the point source weakened it also became redder.Comment: 5 pages, latex, to appear in Gamma-Ray Bursts, 4-th Huntsville Symposium, eds Meegan, Preece, Koshu

Inner disc rearrangement revealed by dramatic brightness variations in the young star PV Cep

Young Sun-like stars at the beginning of the pre-main sequence (PMS) evolution are surrounded by accretion discs and remnant protostellar envelopes. Photometric and spectroscopic variations of these stars are driven by interactions of the star with the disc. Time scales and wavelength dependence of the variability carry information on the physical mechanisms behind these interactions. We conducted multi-epoch, multi-wavelength study of PV Cep, a strongly variable, accreting PMS star. By combining our own observations from 2004-2010 with archival and literature data, we show that PV Cep started a spectacular fading in 2005, reaching an I_C-band amplitude of 4 mag. Analysis of variation of the optical and infrared fluxes, colour indices, and emission line fluxes suggests that the photometric decline in 2005-2009 resulted from an interplay between variable accretion and circumstellar extinction: since the central luminosity of the system is dominated by accretion, a modest drop in the accretion rate could induce the drastic restructuring of the inner disc. Dust condensation in the inner disc region might have resulted in the enhancement of the circumstellar extinction.Comment: 11 pages, 4 figures, accepted for publication by MNRAS. 3 online tables adde