The stability of short-period extrasolar giant planets

A three-dimensional coupled thermosphere-ionosphere model for extrasolar giant planets (EXOTIM) has been developed. This is the first such model reported in the literature. This thesis contains an extensive description of the model and the methods adopted in modelling the different physical processes expected in the upper atmospheres and ionospheres of extrasolar giant planets. Modelling the upper atmosphere is important because the stability of the atmosphere against thermal evaporation is controlled by the conditions in the thermosphere. The thermosphere is heated by the absorption of EUV and X ray (XUV) radiation emitted by the host star. The radiation also ionises the neutral species in the upper atmosphere, which is expected to be composed mainly of molecular and atomic hydrogen, and atomic helium. Ionisation and subsequent photochemistry leads to the formation of the H^+, H^+_2 , H^+_3 , and He^+ ions (and small quantities of HeH^+). H^+_3 emits strongly in the infrared and may act as a significant coolant in gas giant thermospheres. Assuming photochemical equilibrium, the absorption of XUV radiation and ion photochemistry were modelled in a self-consistent fashion. The 3D model can also simulate strong winds affecting the upper atmosphere, and account for both advection and diffusion of the neutral species around the planet. The results indicate that within 1.0 AU from a solar-type host star, the upper atmospheres of Jupiter-type EGPs can be substantially cooler and more stable than implied by studies that ignore the possibility of radiative (H^+_3 ) cooling. In this context, a limiting distance, or a stability limit, was identified for such EGPs that depends on the composition of the upper atmosphere and ionosphere, and within which the atmospheres of the planets undergo hydrodynamic escape. Under restricted conditions, this limit is located around 0.15 AU from a Sun-like host star. The model was also used to simulate a newly found transiting planet HD17156b, which orbits its host star on a highly eccentric orbit

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits : A Multi-Ethnic Meta-Analysis of 45,891 Individuals

J. Kaprio, S. Ripatti ja M.-L. Lokki työryhmien jäseniä.Peer reviewe

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.</p

A century of trends in adult human height

Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5-22.7) and 16.5 cm (13.3-19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8-144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3�6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55 of the global rise in mean BMI from 1985 to 2017�and more than 80 in some low- and middle-income regions�was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing�and in some countries reversal�of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories. © 2019, The Author(s)

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol�which is a marker of cardiovascular risk�changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95 credible interval 3.7 million�4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world. © 2020, The Author(s), under exclusive licence to Springer Nature Limited

The stability of short-period extrasolar giant planets.

A three-dimensional coupled thermosphere-ionosphere model for extrasolar giant planets (EXOTIM) has been developed. This is the first such model reported in the literature. This thesis contains an extensive description of the model and the methods adopted in modelling the different physical processes expected in the upper atmospheres and ionospheres of extrasolar giant planets. Modelling the upper atmosphere is important because the stability of the atmosphere against thermal evaporation is controlled by the conditions in the thermosphere. The thermosphere is heated by the absorption of EUV and X ray (XUV) radiation emitted by the host star. The radiation also ionises the neutral species in the upper atmosphere, which is expected to be composed mainly of molecular and atomic hydrogen, and atomic helium. Ionisation and subsequent photochemistry leads to the formation of the H^+, H^+_2 , H^+_3 , and He^+ ions (and small quantities of HeH^+). H^+_3 emits strongly in the infrared and may act as a significant coolant in gas giant thermospheres. Assuming photochemical equilibrium, the absorption of XUV radiation and ion photochemistry were modelled in a self-consistent fashion. The 3D model can also simulate strong winds affecting the upper atmosphere, and account for both advection and diffusion of the neutral species around the planet. The results indicate that within 1.0 AU from a solar-type host star, the upper atmospheres of Jupiter-type EGPs can be substantially cooler and more stable than implied by studies that ignore the possibility of radiative (H^+_3 ) cooling. In this context, a limiting distance, or a stability limit, was identified for such EGPs that depends on the composition of the upper atmosphere and ionosphere, and within which the atmospheres of the planets undergo hydrodynamic escape. Under restricted conditions, this limit is located around 0.15 AU from a Sun-like host star. The model was also used to simulate a newly found transiting planet HD17156b, which orbits its host star on a highly eccentric orbit.

Atmospheric structure and helium abundance on Saturn from Cassini/UVIS and CIRS observations

International audienc

Catalytic Activity Dependency on Catalyst Components in Aerobic Copper-TEMPO Oxidation

The influence of catalyst components in the copper–TEMPO (2,2,6,6-tetramethylpiperidine N-oxide) catalysed aerobic oxidation of alcohols was investigated. The type and amount of base greatly influences reactivity. The bipyridyl ligand concentration had no major influence on catalysis, but excessive amounts led to a decrease in activity for longer reaction times. The kinetic dependency for TEMPO was found to be 1.15, and for copper 2.25, which is an indication of a binuclear catalytic system. Optimised conditions with various allylic and aliphatic alcohols give good to excellent rapid oxidations.Peer reviewe

Titan in transit: Ultraviolet stellar occultation observations reveal a complex atmospheric structure

Transit spectroscopy is a key tool for exoplanet atmospheric characterization. However, transit spectrum observations can be limited by aerosol extinction when gas opacities are weak. The ultraviolet wavelength range contains a variety of strong molecular and atomic features, potentially enabling gas species detection even when atmospheric hazes are present. To understand the interplay between aerosol extinction and ultraviolet molecular opacities, we investigate transmission through the atmosphere of Saturn's moon Titan during an occultation observed with the Ultraviolet Imaging Spectrometer (UVIS) on board NASA's Cassini orbiter. We analyze the derived ultraviolet transit spectrum of Titan using exoplanet-relevant atmospheric retrieval models that both include and exclude treatments for hazes. Our retrieved gas column densities are consistent with previous studies analyzing UVIS occultation data. Despite the apparent haze impact on the underlying occultation data, our treatments fail to correctly characterize the haze in fits derived from simulated transit observations. This suggests that oversimplified haze parameterizations can hinder detection of atmospheric hazes in transit. Our work indicates that continued characterization of exoplanets in the ultraviolet wavelength regime can provide novel atmospheric constraints even if transit spectra are dominated by haze extinction at longer wavelengths. © 2021 The Author(s).Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]