Observations on Fishes Previously Unrecorded or Rarely Encountered in the Northeastern Gulf of Mexico

Twenty-one species of marine fishes previously unrecorded or rarely encountered in the northeastern Gulf of Mexico were taken by trawl, dredge, spear or hand capture or observed by SCUBA or research submersible. Biological data are added to the knowledge of all these forms, and several species are shown to have permanent populations in the region

Depositional Setting and Quaternary Stratigraphy of the Sheepscot Estuary, Maine: A Preliminary Report

The Sheepscot River estuary in west-central coastal Maine is a typical example of a long linear embayment sculpted by glacial ice flowing nearly parallel to bedrock strike. After initial déglaciation 13,500 yrs. BP it was covered by glaciomarine mud, the Presumpscot Formation. Isostatic rebound resulted in a rapid sea-level fall and the channeling, winnowing, and consolidation of the Presumpscot Formation, until sea-level reached a lowstand about 65 m below present, 9500 yrs. BP. Subsequent sea-level rise caused flooding of the paleovalley of the Sheepscot, with reworking of the Pleistocene. High resolution seismic reflection profiling, vibracoring, and surficial mapping has allowed reconstruction of the Quaternary stratigraphy and the generation of an evolutionary model of sedimentary environments. At present the estuary exhibits three zones : an outer zone stripped of sediment, a middle zone undergoing erosion by tidal currents and slumping on bluffs and channel margins, and an inner zone of sediment accumulation on flats and in marshes, with redistribution of sediments by tidal currents. This three-fold division held throughout the Holocene transgression, with sediments being temporarily stored in the upper regions of the estuary, and reworked as sea-level rise continued.L'estuaire de la rivière Sheepscot, au centre-ouest de la région côtière du Maine, est un bel exemple de baie allongée, sculptée par un glacier qui s'écoulait parallèlement à la direction du substratum rocheux. Après le début de la déglaciation, vers 13 500 BP, l'estuaire a été recouvert d'une boue glaciomarine, la Formation de Presumpscot. Le relèvement isostatique a eu pour conséquence la baisse rapide du niveau marin ainsi que la formation de chenaux, le triage des sédiments et la consolidation de la Formation de Presumpscot, jusqu'à 9500 BP, alors que le niveau marin était à 65 m sous le niveau actuel. La hausse subséquente du niveau marin a entraîné l'ennoiement de la paléo-vallée du Sheepscot, puis remaniement des sédiments au Pléistocène. Les sondages sismiques par réflexion, les vibro-carottages et la cartographie des formations superficielles ont permis de reconstituer la stratigraphie du Quaternaire et de créer un modèle de l'évolution des milieux de sédimentation. Actuellement, l'estuaire se divise en trois zones: une zone externe, décapée; une zone centrale en voie d'érosion par les courants de marée et affectée par des glissements dans les falaises et sur les bords des chenaux; une zone interne d'accumulation sur les hauts-fonds et dans les marais et de redistribution des sédiments par les courants de marée. Cette division zonale s'est maintenue tout au long de la transgression survenue à l'Holocène, avec accumulation des sédiments en amont de l'estuaire et remaniement au fur et à mesure de la hausse du niveau marin.Das Sheepscot-FlufJmùndungsbecken an der zentralen Westkùste von Maine ist ein Typisches Beispiel einer langen linearen Bucht, die durch glaziales EisflieBen fast parallel zur Fels-Streichrichtung geformt wurde. Nach dem Beginn der Enteisung 13,500 Jahre v.u.Z. war das Mùndungsbecken mit glazialmarinem Schlamm bedeckt, der Presumpscot Formation. Die isostatische Hebung fùhrte zu einem schnellen Sinken des Meeresniveaus und zur Bildung von Kanâlen, Sortierung und Konsolidierung der Presumpscot Formation, bis das Meeresniveau 9500 Jahre v.u.Z. einen Niedrigstand von ungefàhr 65 m unter dem heutigen Niveau erreichte. Das anschliepende Ansteigen des Meeresniveaus fùhrte zur Ùberschwemmung des Paleo-Tals von Sheepscot und zur Neuorganisation der Sedimente im Pleistozàn. Mittels seismischer Reflexionsprofile, Vibra-Karottage und Kartographie der Oberflâchen konnte die Stratigraphie des Quaternàrs rekonstruiert werden und ein Modell der Entwicklung der Sediment-Umgebungen geschaffen werden. Gegenwàrtig hat das Mùndungsbecken drei Zonen: eine àupere, von Sedimenten befreite Zone; eine mittlere Zone, die wegen der Gezeiten-Strômungen und der Erdrutsche an den Steilufern und den Ufern der Kanàle der Erosion ausgesetzt ist; eine innere Zone von Sediment-AbIagerungen in den Niederungen und Mârschen mit Neuverteilung der Sedimente durch die Gezeiten-Strômungen. Dièse dreiteilige Aufteilung hielt sich wàhrend der ganzen Transgression im Holozàn, mit Sedimenten, die zeitweise in den oberen Regionen der Mùndungsbucht abgelagert wurden und die, als das Steigen des Meeresniveaus weiterging, neu organisiert wurden

Understanding food consumption lifecycles using wearable cameras

Application of design in HCI is a common approach to engendering behavioural change to address important challenges such as sustainability. Encouraging such change requires an understanding of current motivations and behaviours in the domain in question. In this paper, we describe use of wearable cameras to study motivations and behaviours around food consumption by focusing on two contrasting cultures, Malaysia and the UK. Our findings highlight the potential of wearable cameras to enhance knowledge of food consumption practices and identify where and how some digital interventions might be appropriate to change food behaviour. This includes appealing to people’s motivations behind food consumption and capitalising on existing practices such as gifting of food and social meals. We propose a food consumption lifecycle as a framework to understand and design human–food interaction. The use of wearable cameras enabled us to capture a high-level overview of spatially distributed food-related practices and understand food behaviours in greater depth.This work was co-funded by Horizon Digital Economy Research Institute, UK, and Crops for the Future, Malaysia.This is the author accepted manuscript. The final version is available from Springer via http://dx.doi.org/10.1007/s00779-015-0871-

Development Toward a Ground-Based Interferometric Phased Array for Radio Detection of High Energy Neutrinos

The in-ice radio interferometric phased array technique for detection of high energy neutrinos looks for Askaryan emission from neutrinos interacting in large volumes of glacial ice, and is being developed as a way to achieve a low energy threshold and a large effective volume at high energies. The technique is based on coherently summing the impulsive Askaryan signal from multiple antennas, which increases the signal-to-noise ratio for weak signals. We report here on measurements and a simulation of thermal noise correlations between nearby antennas, beamforming of impulsive signals, and a measurement of the expected improvement in trigger efficiency through the phased array technique. We also discuss the noise environment observed with an analog phased array at Summit Station, Greenland, a possible site for an interferometric phased array for radio detection of high energy neutrinos.Comment: 13 Pages, 14 Figure

Examining the Classification Accuracy of TSVMs with Feature Selection in Comparison with the GLAD Algorithm

Gene expression data sets are used to classify and predict patient diagnostic categories. As we know, it is extremely difficult and expensive to obtain gene expression labelled examples. Moreover, conventional supervised approaches cannot function properly when labelled data (training examples) are insufficient using Support Vector Machines (SVM) algorithms. Therefore, in this paper, we suggest Transductive Support Vector Machines (TSVMs) as semi-supervised learning algorithms, learning with both labelled samples data and unlabelled samples to perform the classification of microarray data. To prune the superfluous genes and samples we used a feature selection method called Recursive Feature Elimination (RFE), which is supposed to enhance the output of classification and avoid the local optimization problem. We examined the classification prediction accuracy of the TSVM-RFE algorithm in comparison with the Genetic Learning Across Datasets (GLAD) algorithm, as both are semi-supervised learning methods. Comparing these two methods, we found that the TSVM-RFE surpassed both a SVM using RFE and GLAD

Bayesian hierarchical clustering for studying cancer gene expression data with unknown statistics

Clustering analysis is an important tool in studying gene expression data. The Bayesian hierarchical clustering (BHC) algorithm can automatically infer the number of clusters and uses Bayesian model selection to improve clustering quality. In this paper, we present an extension of the BHC algorithm. Our Gaussian BHC (GBHC) algorithm represents data as a mixture of Gaussian distributions. It uses normal-gamma distribution as a conjugate prior on the mean and precision of each of the Gaussian components. We tested GBHC over 11 cancer and 3 synthetic datasets. The results on cancer datasets show that in sample clustering, GBHC on average produces a clustering partition that is more concordant with the ground truth than those obtained from other commonly used algorithms. Furthermore, GBHC frequently infers the number of clusters that is often close to the ground truth. In gene clustering, GBHC also produces a clustering partition that is more biologically plausible than several other state-of-the-art methods. This suggests GBHC as an alternative tool for studying gene expression data. The implementation of GBHC is available at https://sites. google.com/site/gaussianbhc

The Daalbirrwirr Gamambigu (Safe Children) Model: Embedding Cultural Safety in Child Protection Responses for Australian Aboriginal Children in Hospital Settings.

The aim of this paper is to describe the development of a model of care to embed cultural safety for Aboriginal children into paediatric hospital settings. The Daalbirrwirr Gamambigu (pronounced "Dahl-beer-weer gum-um-be-goo" in the Gumbaynggirr language means 'safe children') model encompasses child protection responses at clinical, managerial and organisational levels of health services. A review of scholarly articles and grey literature followed by qualitative interviews with Aboriginal health professionals formed the evidence base for the model, which then underwent rounds of consultation for cultural suitability and clinical utility. Culturally appropriate communication with children and their families using clinical yarning and a culturally adapted version of ISBAR (a mnemonic for Identify, Situation, Background, Assessment and Recommendation) for interprofessional communication is recommended. The model guides the development of a critical consciousness about cultural safety in health care settings, and privileges the cultural voices of many diverse Aboriginal peoples. When adapted appropriately for local clinical and cultural contexts, it will contribute to a patient journey experience of respect, dignity and empowerment

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

BCL6 is a transcriptional repressor that is over-expressed due to chromosomal translocations, or other abnormalities, in ~40% of diffuse large B-cell lymphoma. BCL6 interacts with co-repressor, SMRT, and this is essential for its role in lymphomas. Peptide or small molecule inhibitors, which prevent the association of SMRT with BCL6, inhibit transcriptional repression and cause apoptosis of lymphoma cells in vitro and in vivo. In order to discover compounds, which have the potential to be developed into BCL6 inhibitors, we screened a natural product library. The ansamycin antibiotic, rifamycin SV, inhibited BCL6 transcriptional repression and NMR spectroscopy confirmed a direct interaction between rifamycin SV and BCL6. To further determine the characteristics of compounds binding to BCL6-POZ we analyzed four other members of this family and showed that rifabutin, bound most strongly. An X-ray crystal structure of the rifabutin-BCL6 complex revealed that rifabutin occupies a partly non-polar pocket making interactions with tyrosine58, asparagine21 and arginine24 of the BCL6-POZ domain. Importantly these residues are also important for the interaction of BLC6 with SMRT. This work demonstrates a unique approach to developing a structure activity relationship for a compound that will form the basis of a therapeutically useful BCL6 inhibitor

Association Among Acrylamide, Blood Insulin, and Insulin Resistance in Adults

OBJECTIVE - Exposure to acrylamide in foodstuffs and smoking has become a worldwide concern. The effect of acrylamide on glucose homeostasis is not known. The goal of the present study Was to test the hypothesis that trace acrylamide exposure might be independently associated With both reduced blood insulin and reduced insulin resistance. RESEARCH DESIGN AND METHODS - We examined 1,356 participants with reliable measures of glucose homeostasis and Hb adducts of acrylamide (HbAA) and glycidamide from the National Health and Nutrition Examination Survey, 2003-2004. Glucose homeostasis was assessed by the measurement of plasma glucose, serum insulin, and the homeostasis model assessment of insulin resistance (HOMA- IR). RESULTS - in a linear regression model, a 1-unit increase in log HbAA was associated with a decrease in serum insulin (beta coefficient = -0.20 +/- 0.05, P = 0.001) and HOMA-IR (beta coefficient = -0.23 +/- 0.05, P < 0.001). After HbAA concentrations were divided into quartiles in the fully adjusted models, the adjusted serum insulin level and HOMA- IR significantly decreased across quartiles of HbAA (P-trend < 0.001 for both ). In subgroup analysis, the association of HbAA levels with HOMA-IR and insulin levels was stronger in subjects who were white or had ever smoked or in subjects With a lower education level or a BMI <25 or >30 kg/m(2). CONCLUSIONS - Acrylamide is associated with reduced serum insulin levels in adults. Further clinical and animal studies are warranted to clarify the putative causal relationship