15,928 research outputs found

    Image Management in a Touristic Destination: A Qualitative Approach Analysis of the Border City of Ciudad Juarez, Mexico

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    This paper summarizes an academic experience. It has been made by the contributions of a group of experts from a Mexican university participating in a discussion panel called "Image of a Touristic Destination". This was done within the framework of the activities carried out during the 8va. Catedra Patrimonial "Sergio Molina" on October 19-21, 2016. The purpose of this paper is to analyze the process of image management of a border touristic destination through the experience of Ciudad Juárez, in order to obtain an improvement in it. The concept of image is analyzed from its components of responsibility and participation in management between Government (message), Society (context), and Universities (management). The methodological approach selected was exploratory. The grounded theory method was selected and thematic analysis with the support of the Atlas-ti software was made. Suggestions are offered for actions which seek to highlight the positive aspects of the city as a touristic destination. The importance of generating responsibility and participation within a social network was highlighted. It was recommended to take advantage of the economic and intellectual resources in education of the Juarez society so that they can know their culture and history

    Winning versus losing during gambling and its neural correlates

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    Humans often make decisions which maximize an internal utility function. For example, humans often maximize their expected reward when gambling and this is considered as a "rational" decision. However, humans tend to change their betting strategies depending on how they "feel". If someone has experienced a losing streak, they may "feel" that they are more likely to win on the next hand even though the odds of the game have not changed. That is, their decisions are driven by their emotional state. In this paper, we investigate how the human brain responds to wins and losses during gambling. Using a combination of local field potential recordings in human subjects performing a financial decision-making task, spectral analyses, and non-parametric cluster statistics, we investigated whether neural responses in different cognitive and limbic brain areas differ between wins and losses after decisions are made. In eleven subjects, the neural activity modulated significantly between win and loss trials in one brain region: the anterior insula (p=0.01p=0.01). In particular, gamma activity (30-70 Hz) increased in the anterior insula when subjects just realized that they won. Modulation of metabolic activity in the anterior insula has been observed previously in functional magnetic resonance imaging studies during decision making and when emotions are elicited. However, our study is able to characterize temporal dynamics of electrical activity in this brain region at the millisecond resolution while decisions are made and after outcomes are revealed

    The effect of caffeine on cognitive performance is influenced by CYP1A2 but not ADORA2A genotype, yet neither genotype affects exercise performance in healthy adults

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    Purpose: To determine the influence of two commonly occurring genetic polymorphisms on exercise, cognitive performance, and caffeine metabolism, after caffeine ingestion. Methods: Eighteen adults received caffeine or placebo (3 mg kg−1) in a randomised crossover study, with measures of endurance exercise (15-min cycling time trial; 70-min post-supplementation) and cognitive performance (psychomotor vigilance test; PVT; pre, 50 and 95-min post-supplementation). Serum caffeine and paraxanthine were measured (pre, 30 and 120-min post-supplementation), and polymorphisms in ADORA2A (rs5751876) and CYP1A2 (rs762551) genes analysed.Results: Caffeine enhanced exercise performance (P  0.05). Caffeine enhanced PVT performance (P  0.05). Serum caffeine and paraxanthine responses were not different between genotypes (P > 0.05).Conclusion: Caffeine enhanced CYP1A2 ‘fast’ metabolisers’ cognitive performance more than ‘slow’ metabolisers. No other between-genotype differences emerged for the effect of caffeine on exercise or cognitive performance, or metabolism

    The untilted diffuse matter Bianchi V Universe

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    A diffuse matter filled Type V Universe is studied. The anisotropic behaviour, the distortion caused to the CMBR and the parameter region allowed by present cosmological bounds are examined. It is shown how the overall sky pattern of temperature anisotropies changes under a non-infinitesimal spatial coordinate transformation that preserves the Type V manifest homogeneity.Comment: (RevTeX) 23 pages, 2 figures, to appear in Physics Letters

    Gln27Glu polymorphism in the beta2 adrenergic receptor gene and lipid metabolism during exercise in obese women

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    BACKGROUND: The Glu27Glu genotype in the beta-2-adrenergic receptor (ADRB2) is associated with fat mass, body mass index and obesity in females. In our population, we previously found an association of higher body mass index (BMI) among women who reported more physical activity and carried the Glu27 allele as compared to non carriers with the same level of activity. OBJECTIVE: To examine the lipid metabolism differences, both at rest and during submaximal exercise in ADRB2 Glu27Glu vs Gln27Gln obese women. SUBJECTS: Eight obese women with the Glu27Glu genotype (age, 43±5 y; body mass index (BMI), 31.7±0.9 kg/m2; percentage fat mass, 42.0±1.3; WHR, 0.83±0.02; and VO2max, 21.6±0.9 ml/kg/min) were compared with seven obese women with the Gln27Gln genotype (age, 43±5 y; BMI, 33.9±1.3 kg/m2; percentage fat mass, 41.6±1.2; WHR, 0.83±0.02; and VO2max, 20.6±0.8 ml/kg/min). MEASUREMENTS: The ADRB2 polymorphism was identified by PCR-RFLP. Respiratory quotient was determined by indirect calorimetry at baseline, during 1 h of walking on a treadmill and 1 h after the exercise. Plasma triglycerides, glycerol, FFA, hydroxybutyrate, glucose and lactate were assayed by spectrophotometric methods. Insulin, leptin and progesterone were measured by radioimmunoassay. Adrenaline and noradrenaline were quantified by high performance liquid chromatography. RESULTS: The ADRB2 Glu27Glu subjects had lower plasma glycerol (P=0.047) and lower hydroxybutyrate (P=0.001) throughout the study than the Gln27Gln group. Plasma triglycerides (P=0.001), lactate (P<0.05) and serum insulin (P<0.05) remained higher in the Glu27Glu group vs the Gln27Gln group. The respiratory quotient (RQ) was higher in the Glu27Glu obese women along the study (P=0.046), and fat oxidation was significantly lower in this group during the recovery (P=0.048). The other variables did not differ statistically between groups. CONCLUSION: These data suggest that both lipolysis and fat oxidation promoted by an acute submaximal exercise intervention could be blunted in the polymorphic ADRB2 Glu27Glu group of our female obese population

    Detection of non-Gaussianity in the WMAP 1-year data using spherical wavelets

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    A non-Gaussian detection in the WMAP 1-year data is reported. The detection has been found in the combined Q-V-W map proposed by the WMAP team (Komatsu et al. 2003) after applying a wavelet technique based on the Spherical Mexican Hat Wavelet (SMHW). The skewness and the kurtosis of the SMHW coefficients are calculated at different scales. A non-Gaussian signal is detected at scales of the SMHW around 4 deg (size in the sky of around 10 deg). The right tail probability of the detection is approx. 0.4%. In addition, a study of Gaussianity is performed in each hemisphere. The northern hemisphere is compatible with Gaussianity, whereas the southern one deviates from Gaussianity with a right tail probability of approx. 0.1%. Systematics, foregrounds and uncertainties in the estimation of the cosmological parameters are carefully studied in order to identify the possible source of non-Gaussianity. The detected deviation from Gaussianity is not found to be caused by systematic effects: 1) each one of the Q, V and W receivers shows the same non-Gaussianity pattern, and 2) several combinations of the different receivers at each frequency band do not show this non-Gaussian pattern. Similarly, galactic foregrounds show a negligible contribution to the non-Gaussian detection: non-Gaussianity is detected in all the WMAP maps and no frequency dependence is observed. Moreover, the expected foreground contribution to the combined WMAP map was added to CMB Gaussian simulations showing a behaviour compatible with the Gaussian model. Influence of uncertainties in the CMB power spectrum estimation are also quantified. Hence, possible intrinsic temperature fluctuations (like secondary anisotropies and primordial features) can not be rejected as the source of this non-Gaussian detection.Comment: 33 pages, 14 figures. Revised to match version accepted for publication in Ap

    The GIRAFFE Inner Bulge Survey (GIBS). I. Survey Description and a kinematical map of the Milky Way bulge

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    The Galactic bulge is a massive, old component of the Milky Way. It is known to host a bar, and it has recently been demonstrated to have a pronounced boxy/peanut structure in its outer region. Several independent studies suggest the presence of more than one stellar populations in the bulge, with different origins and a relative fraction changing across the bulge area. This is the first of a series of papers presenting the results of the Giraffe Inner Bulge Survey, carried out at the ESO-VLT with the multifibre spectrograph FLAMES. Spectra of ~5000 red clump giants in 24 bulge fields have been obtained at resolution R=6500, in the infrared Calcium triplet wavelength region at 8500 {\AA}. They are used to derive radial velocities and metallicities, based on new calibration specifically devised for this project. Radial velocities for another ~1200 bulge red clump giants, obtained from similar archive data, have been added to the sample. Higher resolution spectra have been obtained for 450 additional stars at latitude b=-3.5, with the aim of investigating chemical abundance patterns variations with longitude, across the inner bulge. In total we present here radial velocities for 6392 RC stars. We derive a radial velocity, and velocity dispersion map of the Milky Way bulge, useful to be compared with similar maps of external bulges, and to infer the expected velocities and dispersion at any line of sight. The K-type giants kinematics is consistent with the cylindrical rotation pattern of M-giants from the BRAVA survey. Our sample enables to extend this result to latitude b=-2, closer to the Galactic plane than probed by previous surveys. Finally, we find strong evidence for a velocity dispersion peak at (0,-1) and (0,-2), possibly indicative of a high density peak in the central 250 pc of the bulgeComment: A&A in pres

    The potential of a sustainable municipal waste management system for Santiago de Chile, including energy production from waste

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    Background: Due to a rapid urbanization process in the Metropolitan Region of Santiago de Chile (MRS), the amount of municipal solid waste (MSW) generated has increased considerably within the last years. MSW should be managed properly in order to achieve sustainable development. The purpose of this study is to analyze MSW management in MRS on the basis of three different explorative scenarios for the year 2030. Methods: The Integrative Sustainability Concept of the Helmholtz Association provided a conceptual framework for the study and was used to evaluate the scenarios. One important topic within the field of management of MSW in the year 2030 will be the contribution of waste treatment technologies to energy production, e.g., by the use of landfill gas and by separated collection of biowaste followed by anaerobic treatment. Results: The largest sustainability deficits in the scenarios are the small proportion of MSW being pre-treated before final disposal and the greenhouse gas (GHG) emissions associated with MSW disposal. MSW management technologies taken into consideration were mechanical biological treatment, energy recovery from MSW in anaerobic digestion plants with biogas production, the production of refuse-derived fuel and its use as a secondary fuel, as well as electricity generation from landfill gas. Energy generation from MSW in 2030 will be about 6% of electricity consumption in 2010. Conclusions: The three scenarios show some sustainability deficits. Even so, there are some improvements such as the reduction of GHG emissions and - even though marginal - energy supply for MRS from renewable energy sources

    Different Impacts of Cardiovascular Risk Factors on Oxidative Stress

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    The objective of the study was to evaluate oxidative stress (OS) status in subjects with different cardiovascular risk factors. With this in mind, we have studied three models of high cardiovascular risk: hypertension (HT) with and without metabolic syndrome, familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH) with and without insulin resistance. Oxidative stress markers (oxidized/reduced glutathione ratio, 8-oxo-deoxyguanosine and malondialdehide) together with the activity of antioxidant enzyme triad (superoxide dismutase, catalase, glutathione peroxidase) and activation of both pro-oxidant enzyme (NAPDH oxidase components) and AGTR1 genes, as well as antioxidant enzyme genes (CuZn-SOD, CAT, GPX1, GSR, GSS and TXN) were measured in mononuclear cells of controls (n = 20) and patients (n = 90) by assessing mRNA levels. Activity of some of these antioxidant enzymes was also tested. An increase in OS and pro-oxidant gene mRNA values was observed in patients compared to controls. The hypertensive group showed not only the highest OS values, but also the highest pro-oxidant activation compared to those observed in the other groups. In addition, in HT a significantly reduced antioxidant activity and mRNA induction of antioxidant genes were found when compared to controls and the other groups. In FH and FCH, the activation of pro-oxidant enzymes was also higher and antioxidant ones lower than in the control group, although it did not reach the values obtained in hypertensives. The thioredoxin system was more activated in patients as compared to controls, and the highest levels were in hypertensives. The increased oxidative status in the presence of cardiovascular risk factors is a consequence of both the activation of pro-oxidant mechanisms and the reduction of the antioxidant ones. The altered response of the main cytoplasmic antioxidant systems largely contributes to OS despite the apparent attempt of the thioredoxin system to control it

    Gamma Ray Burst Neutrinos Probing Quantum Gravity

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    Very high energy, short wavelength, neutrinos may interact with the space-time foam predicted by theories of quantum gravity. They would propagate like light through a crystal lattice and be delayed, with the delay depending on the energy. This will appear to the observer as a violation of Lorenz invariance. Back of the envelope calculations imply that observations of neutrinos produced by gamma ray bursts may reach Planck-scale sensitivity. We revisit the problem considering two essential complications: the imprecise timing of the neutrinos associated with their poorly understood production mechanism in the source and the indirect nature of their energy measurement made by high energy neutrino telescopes.Comment: 14 pages, 2 figure
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