The detection and classification of blast cell in Leukaemia Acute Promyelocytic Leukaemia (AML M3) blood using simulated annealing and neural networks

This paper was delivered at AIME 2011: 13th Conference on Artifical Intelligence in Medicine.This paper presents a method for the detection and classification of blast cells in M3 with others sub-types using simulated annealing and neural networks. In this paper, we increased our test result from 10 images to 20 images. We performed Hill Climbing, Simulated Annealing and Genetic Algorithms for detecting the blast cells. As a result, simulated annealing is the “best” heuristic search for detecting the leukaemia cells. From the detection, we performed features extraction on the blast cells and we classifying based on M3 and other sub-types using neural networks. We received convincing result which has targeting around 97% in classifying of M3 with other sub-types. Our results are based on real world image data from a Haematology Department.Universiti Sains Islam Malaysia and the Ministry of Higher Education, Malaysi

Melanism as a potential thermal benefit in eastern fox squirrels (Sciurus niger)

Melanistic fox squirrels (Sciurus niger) have expanded westward and increased in frequency in the Omaha, Nebraska, and Council Bluffs, Iowa, metropolitan areas. The selective advantage of melanism is currently unknown, but thermal advantages have been hypothesized, especially in winter. No difference in metabolic response curves were measured between melanistic (black) and rufus (orange) fox squirrels. When exposed to sunny skies, both melanistic and rufus squirrels had higher surface (skin and fur) temperature as ambient temperatures increased. Melanistic squirrel surface temperatures did not differ when squirrels were exposed to sunny or cloudy skies. However, rufus individuals showed significantly lower increases in surface temperatures when under cloudy skies. During fall months, rufus individuals were about 1.5 times more active throughout the day than melanistic individuals. However, in winter, melanistic fox squirrels were approximately 30% more active in the mornings (before 13:00) compared to rufus squirrels. Pre-winter body condition was higher in melanistic (25.5 ± 1.8 g/cm) compared to rufus (20.30 ± 3.6 g/cm) fox squirrels; however, there were no significant differences between melanistic (22.8 ± 1.4 g/cm) and rufus (23.9 ± 0.8 g/cm) fox squirrel post-winter body condition. The results of this study indicate that melanistic fox squirrels may have a slight winter thermal advantage over rufus fox squirrels by maintaining higher skin temperatures

High-fidelity simulation of an ultrasonic standing-wave thermoacoustic engine with bulk viscosity effects

We have carried out boundary-layer-resolved, unstructured fully-compressible Navier--Stokes simulations of an ultrasonic standing-wave thermoacoustic engine (TAE) model. The model is constructed as a quarter-wavelength engine, approximately 4 mm by 4 mm in size and operating at 25 kHz, and comprises a thermoacoustic stack and a coin-shaped cavity, a design inspired by Flitcroft and Symko (2013). Thermal and viscous boundary layers (order of 10 $\mathrm{\mu}$m) are resolved. Vibrational and rotational molecular relaxation are modeled with an effective bulk viscosity coefficient modifying the viscous stress tensor. The effective bulk viscosity coefficient is estimated from the difference between theoretical and semi-empirical attenuation curves. Contributions to the effective bulk viscosity coefficient can be identified as from vibrational and rotational molecular relaxation. The inclusion of the coefficient captures acoustic absorption from infrasonic ($\sim$10 Hz) to ultrasonic ($\sim$100 kHz) frequencies. The value of bulk viscosity depends on pressure, temperature, and frequency, as well as the relative humidity of the working fluid. Simulations of the TAE are carried out to the limit cycle, with growth rates and limit-cycle amplitudes varying non-monotonically with the magnitude of bulk viscosity, reaching a maximum for a relative humidity level of 5%. A corresponding linear model with minor losses was developed; the linear model overpredicts transient growth rate but gives an accurate estimate of limit cycle behavior. An improved understanding of thermoacoustic energy conversion in the ultrasonic regime based on a high-fidelity computational framework will help to further improve the power density advantages of small-scale thermoacoustic engines.Comment: 55th AIAA Aerospace Sciences Meeting, AIAA SciTech, 201

Direct comparison between satellite electric field measurements and the visual aurora

Electric field data from two passes of the Injun 5 satellite, one corresponding to magnetically quiet conditions and one corresponding to substorm conditions, are compared with simultaneous all-sky-camera data from College, Alaska. In each case, a significant deviation of the electric field from the expected V x B field (where V is the satellite velocity) was evident and a distinct electric field reversal could be identified. In the region of substantial electric field equatorward of the electric field reversal a diffuse auroral arc was observed during the magnetically quiet pass and auroral patches were observed during the substorm pass. The motion of the auroral patches was consistent with the general direction and magnitude of the E x B drift computed from the satellite electric field measurements. In the substorm case the electric field reversal occurred very near a discrete auroral arc at the poleward side of the diffuse arcs and patches. Comparison of the quiet time and substorm cases suggests that the convection electric field penetrates deeper into the magnetosphere during a substorm

Quantum diagonalization of Hermitean matrices

To measure an observable of a quantum mechanical system leaves it in one of its eigenstates and the result of the measurement is one of its eigenvalues. This process is shown to be a computational resource: Hermitean (N ×N) matrices can be diagonalized, in principle, by performing appropriate quantum mechanical measurements. To do so, one considers the given matrix as an observable of a single spin with appropriate length s which can be measured using a generalized Stern-Gerlach apparatus. Then, each run provides one eigenvalue of the observable. As the underlying working principle is the `collapse of the wavefunction' associated with a measurement, the procedure is neither a digital nor an analogue calculation - it defines thus a new example of a quantum mechanical method of computation

Explanation for Anomalous Shock Temperatures Measured by Neutron Resonance Spectroscopy

Neutron resonance spectrometry (NRS) has been used to measure the temperature inside Mo samples during shock loading. The temperatures obtained were significantly higher than predicted assuming ideal hydrodynamic loading. The effect of plastic flow and non-ideal projectile behavior were assessed. Plastic flow was calculated self-consistently with the shock jump conditions: this is necessary for a rigorous estimate of the locus of shock states accessible. Plastic flow was estimated to contribute a temperature rise of 53K compared with hydrodynamic flow. Simulations were performed of the operation of the explosively-driven projectile system used to induce the shock in the Mo sample. The simulations predicted that the projectile was significantly curved on impact, and still accelerating. The resulting spatial variations in load, including radial components of velocity, were predicted to increase the apparent temperature that would be deduced from the width of the neutron resonance by 160K. These corrections are sufficient to reconcile the apparent temperatures deduced using NRS with the accepted properties of Mo, in particular its equation of state.Comment: near-final version, waiting for final consent from an autho

Inelastic collapse of a randomly forced particle

We consider a randomly forced particle moving in a finite region, which rebounds inelastically with coefficient of restitution r on collision with the boundaries. We show that there is a transition at a critical value of r, r_c\equiv e^{-\pi/\sqrt{3}}, above which the dynamics is ergodic but beneath which the particle undergoes inelastic collapse, coming to rest after an infinite number of collisions in a finite time. The value of r_c is argued to be independent of the size of the region or the presence of a viscous damping term in the equation of motion.Comment: 4 pages, REVTEX, 2 EPS figures, uses multicol.sty and epsf.st

Decomposition of coarse woody debris in a long-term litter manipulation experiment: A focus on nutrient availability

The majority of above-ground carbon in tropical forests is stored in wood, which is returned to the atmosphere during decomposition of coarse woody debris. However, the factors controlling wood decomposition have not been experimentally manipulated over time scales comparable to the length of this process.We hypothesized that wood decomposition is limited by nutrient availability and tested this hypothesis in a long-term litter addition and removal experiment in a lowland tropical forest in Panama. Specifically, we quantified decomposition using a 15-year chronosequence of decaying boles, and measured respiration rates and nutrient limitation of wood decomposer communities.The long-term probability that a dead tree completely decomposed was decreased in plots where litter was removed, but did not differ between litter addition and control treatments. Similarly, respiration rates of wood decomposer communities were greater in control treatments relative to litter removal plots; litter addition treatments did not differ from either of the other treatments. Respiration rates increased in response to nutrient addition (nitrogen, phosphorus, and potassium) in the litter removal and addition treatments, but not in the controls.Established decreases in concentrations of soil nutrients in litter removal plots and increased respiration rates in response to nutrient addition suggest that reduced rates of wood decomposition after litter removal were caused by decreased nutrient availability. The effects of litter manipulations differed directionally from a previous short-term decomposition study in the same plots, and reduced rates of bole decomposition in litter removal plots did not emerge until after more than 6 years of decomposition. These differences suggest that litter-mediated effects on nutrient dynamics have complex interactions with decomposition over time

Kepler-445, Kepler-446 And The Occurrence Of Compact Multiples Orbiting Mid-M Dwarf Stars

We confirm and characterize the exoplanetary systems Kepler-445 and Kepler-446: two mid-M dwarf stars, each with multiple, small, short-period transiting planets. Kepler-445 is a metal-rich ([ Fe/H] = + 0.25 0.10) M4 dwarf with three transiting planets, and Kepler-446 is a metal-poor ([ Fe/H] = -0.30 0.10) M4 dwarf also with three transiting planets. Kepler-445c is similar toGJ 1214b: both in planetary radius and the properties of the host star. The Kepler-446 system is similar to the Kepler-42 system: both are metal-poor with large galactic space velocities and three short-period, likely rocky transiting planets that were initially assigned erroneously large planet-to-star radius ratios. We independently determined stellar parameters from spectroscopy and searched for and fitted the transit light curves for the planets, imposing a strict prior on stellar density in order to remove correlations between the fitted impact parameter and planet-to-star radius ratio for short-duration transits. Combining Kepler-445, Kepler-446, and Kepler-42, and isolating all mid-M dwarf stars observed by Kepler with the precision necessary to detect similar systems, we calculate that 21+ 7 -5 % of mid-M dwarf stars host compact multiples ( multiple planets with periods of less than 10 days) for a wide range of metallicities. We suggest that the inferred planet masses for these systems support highly efficient accretion of protoplanetary disk metals by mid-M dwarf protoplanets.NSF DGE1144152, AST-1005313NASA NAS5-26555NASA Office of Space Science NNX13AC07GAstronom