SOLVENT EFFECT ON PHOTOSTABILITY OF BUTYL METHOXY DI BENZOYL METHANE FORMULATED IN SOLUTION AND EMULSION

Objective: The current study was undertaken to correlate the impact of some cosmetics solvents in the photostability of butyl methoxy dibenzoyl methane (BMDBM) into systems with an increasing order of complexity, from simple solutions to emulsions.Methods: Solutions and emulsions containing BMDBM in different solvents were prepared and evaluated using spectrophotometer or transmittance analyzer, respectively. Also, emulsions containing BMDBM in combination with octyl methoxycinnamate (OMC) in ratio 1:1 and 1: 2, and in the presence of octocrylene in the ratio 1:2:1 were prepared. The percentage of decay absorbance at 356 nm was measured before and after irradiation at 500 W/m2 at intervals of 20 min until completing 100 min. Finally, a photolysis assay was carried to analyze deoxygenated and not BMDBM solutions.Results: The absorbance decay of BMDBM in solution was higher in solvents such as mineral oil, isopropyl palmitate and isopropyl myristate. Also, it was observed that concentration and degassing had an effect on the decay kinetics. In emulsions containing only, BMDBM, the absorbance decay did not exceed 20% in all solvents, suggesting a protective effect of the matrix. In the contrary, a decay of 90% was observed in emulsion containing BMDBM and OMC in a 1:2 ratio. When Oct was added to that emulsion, stabilization on the absorbance decay of BMDBM was detected.Conclusion: This study evidenced that the photochemistry of BMDBM is different in solutions and in emulsions. In solutions, the nature of solvents was important, while in emulsions the nature of UVB filters played a pivotal role in the stability of BMDBM.Â

Health education & e_health literacy

info:eu-repo/semantics/publishedVersio

Graphene-based electrodes for silicon heterojunction solar cell technology

Transparent conductive electrodes based on graphene have been previously proposed as an attractive candidate for optoelectronic devices. While graphene alone lacks the antireflectance properties needed in many applications, it can still be coupled with traditional transparent conductive oxides, further enhancing their electrical performance. In this work, the effect of combining indium tin oxide with between one and three graphene monolayers as the top electrode in silicon heterojunction solar cells is analyzed. Prior to the metal grid deposition, the electrical conductance of the hybrid electrodes was evaluated through reflection-mode terahertz time-domain spectroscopy. The obtained conductance maps showed a clear electrical improvement with each additional graphene sheet. In the electrical characterization of the finished solar cells, this translated to a meaningful reduction in the series resistance and an increase in the devices’ fill factor. On the other hand, each additional sheet absorbs part of the incoming radiation, causing the short circuit current to simultaneously decrease. Consequently, additional graphene monolayers past the first one did not further enhance the efficiency of the reference cells. Ultimately, the increase obtained in the fill factor endorses graphene-based hybrid electrodes as a potential concept for improving solar cells’ efficiency in future novel designs.This research was funded by DIGRAFEN, grant number ENE2017–88065-C2-2-R. The APC was funded by the Ministry of Economy, Industry and Competitiveness from Spain. das-Nano and UPNA would also like to acknowledge the funding from the Government of Navarra and the European Regional Development Fund (ERDF), 2020 I + D projects: ref. 0011-1365-2020-000026 for das-Nano and ref. 0011-1365-2020-000045 for UPNA

Genetic variability in two spanish horse populations: preliminary results

The genetic variability has been analyzed through the allelic frequencies distribution of ten STR (Short Tandem Repeat) equine loci of three different horse populations, Asturcón, Pottoka and Thoroughbred (PSI), which is considered as an outgroup. The genetic variability found in the pony breeds is higher than for PSI and only one of the ten loci analyzed is significantly desviated from Hardy-Weinberg equilibrium (= 0.01) in Asturcón and Pottoka populations. The FST value (0.054) shows a significant divergence between Asturcón and Pottoka, besides the genetic distance calculated between both populations is very lower compared to their relation with PSI.Para el estudio de la variabilidad genética de tres poblaciones diferentes de caballos, Asturcón, Pottoka y Pura Sangre Inglés (PSI), habiéndose constituido esta última como población de referencia, se ha analizado la distribución de las frecuencias alélicas de 10 STR (Short Tandem Repeat) loci equinos. La variabilidad genética encontrada en las razas de ponis es superior a la del PSI y solo uno de los loci analizados se desvía significativamente del equilibrio Hardy- Weinberg (=0,01) en las poblaciones de Asturcón y Pottoka. El valor FST estimado (0,054) muestra una divergencia significativa entre Asturcón y Pottoka, asimismo la distancia genética calculada entre ambas poblaciones es inferior comparada a la que tienen ambas con respecto al PSI

Mechanisms involved in the aging-induced vascular dysfunction

This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionVascular aging is a key process determining health status of aged population. Aging is an independent cardiovascular risk factor associated to an impairment of endothelial function, which is a very early and important event leading to cardiovascular disease. Vascular aging, formerly being considered an immutable and inexorable risk factor, is now viewed as a target process for intervention in order to achieve a healthier old age. A further knowledge of the mechanisms underlying the age-related vascular dysfunction is required to design an adequate therapeutic strategy to prevent or restore this impairment of vascular functionality. Among the proposed mechanisms that contribute to age-dependent endothelial dysfunction, this review is focused on the following aspects occurring into the vascular wall: (1) the reduction of nitric oxide (NO) bioavailability, caused by diminished NO synthesis and/or by augmented NO scavenging due to oxidative stress, leading to peroxynitrite formation (ONOO -); (2) the possible sources involved in the enhancement of oxidative stress; (3) the increased activity of vasoconstrictor factors; and (4) the development of a low-grade pro-inflammatory environment. Synergisms and interactions between all these pathways are also analyzed. Finally, a brief summary of some cellular mechanisms related to endothelial cell senescence (including telomere and telomerase, stress-induced senescence, as well as sirtuins) are implemented, as they are likely involved in the age-dependent endothelial dysfunction, as well as in the lower vascular repairing capacity observed in the elderly. Prevention or reversion of those mechanisms leading to endothelial dysfunction through life style modifications or pharmacological interventions could markedly improve cardiovascular health in older peopleThis study is supported by grants from Ministerio de Ciencia e Innovación (Instituto de Salud Carlos III, RETICEF RD06/0013; PI08/1649; SAF2011-28011; SAF2011-24684, Spanish Government, and Sociedad Española de Farmacología/Almirall Prodesfarm

Restauración de montes quemados en condiciones mediterráneas

Wildfires may produce ecosystem damages that would require post-fire mitigation and/or restoration actions. The question is what are the criteria to identify those burned areas that show high degradation risk in order to plan and prioritise restoration projects. To address that question it is necessary to start with the analysis of fire impact, and from that analysis to derive predictive tools for assessing the fragility and regeneration capacity of burned ecosystems. The identification of post-fire degradation mechanisms provides the basis for developing the corresponding specific mitigation/restoration actions. The diagnostic of ecological impact of wildfires together with the established forest management objectives allow deriving mitigation/restoration strategies and the subsequent implementation projects. We present our experience on the evaluation of post-fire ecosystem vulnerability and on the assessment of restoration planning derived from recent and ongoing EC research projects. This includes the development of shortterm restoration techniques suited for degraded soils and dry Mediterranean conditions, where fire-induced degradation is complicated with water shortage for regenerating vegetation

Entrevista con Fabián Severo

Interview with Fabián SeveroEl encuentro con el escritor uruguayo Fabián Severo se dio de manera virtual, teniendo como punto de partida la lectura de su última novela Sepulturadurante el curso “Literaturas latinoamericanas transculturales” impartido por la doctora Karen Sabán en la Universidad de Heidelberg, Alemania. La novela presenta un diálogo entre un anciano y una mujer joven que regresa al pueblo de sus abuelos para buscar los rastros de su familia, y en esta conversación que ambos sostienen se mezclan las memorias, las voces y los sonidos de un pueblo violentamente silenciado y dividido en dos. A partir de esto, en la entrevista se abordó el tema de la lengua y la identidad en el espacio fronterizo, así como la importancia de la voz y la memoria. También se habló acerca de la traducción de la novela, que fue escrita en portuñol, y los problemas en la enseñanza de la literatura desde la experiencia del escritor.

Automation Proposal for the Intermediate Steps in the 16S FFPE Samples Analysis Pipeline

Cursos e Congresos, C-155[Abstract] In the day-to-day work of bioinformatics, the use of integrated software packages, which encompass a wide range of tools, enables the development of pipelines for omics data analysis. Within the various existing pipelines, we focus on the analysis of the 16S rRNA gene as it allows for the study of diversity and taxonomy of prokaryotic microorganisms such as Bacteria and Archaea. However, these pipelines often involve a sequence of multiple tools that require intermediate steps before further processing can proceed, as in the case between Cutadapt and DADA2. In fact, in a typical pipeline, the values for DADA2 input arguments ’trunc-len-f’ and ’trunc-len-r’ are extracted from the output of Cutadapt. The best approach for selecting optimal values (aka the trimming positions) is graphically visualizing Cutadapt output and manually selecting the most accurate trimming position length. Therefore, we propose the automation of this specific intermediate step between Cutadapt and DADA2 tools, by selecting values displayed in the graphs that meet the filtering criteria. This automation has been incorporated into a custom pipeline for the analysis of the microbiome in 16S paired-end samples from colorectal cancer patients, and could potentially serve as a standardization approach in these processesThe authors of this paper extend their sincere appreciation to the collaborative efforts and contributions of the meiGAbiome Group, aswell as the entire team of medical and anatomopathologists. Finally, we are deeply grateful to the patients whose selfless donations have made this and numerous other studies possibl

Restauración de montes quemados en condiciones mediterráneas

Wildfires may produce ecosystem damages that would require post-fire mitigation and/or restoration actions. The question is what are the criteria to identify those burned areas that show high degradation risk in order to plan and prioritise restoration projects. To address that question it is necessary to start with the analysis of fire impact, and from that analysis to derive predictive tools for assessing the fragility and regeneration capacity of burned ecosystems. The identification of post-fire degradation mechanisms provides the basis for developing the corresponding specific mitigation/restoration actions. The diagnostic of ecological impact of wildfires together with the established forest management objectives allow deriving mitigation/restoration strategies and the subsequent implementation projects. We present our experience on the evaluation of post-fire ecosystem vulnerability and on the assessment of restoration planning derived from recent and ongoing EC research projects. This includes the development of short-term restoration techniques suited for degraded soils and dry Mediterranean conditions, where fire-induced degradation is complicated with water shortage for regenerating vegetation