Goal framing of health related behaviors: What factors contribute to the persuasiveness of a message?

There is evidence that the manner in which relevant information is framed can influence decisions that are based on that information. That is, information may be presented in a positive frame (i.e., describing benefits gained from engaging in behaviors) or in a negative frame (i.e., describing losses from not engaging in behaviors). The effect of information frame on older adults\u27 decision to comply or not comply with health behavior recommendations is unclear due to a paucity of research. In an attempt to understand factors that influence older adult healthy behavior decision making, the current study examined variables that might predict whether positively or negatively framed information elicits greater compliance with health recommendations. Positively and negatively framed messages promoting skin cancer prevention and detection were distributed to older and younger adults. Participants rated their intentions to engage in prevention and detection behaviors. Intentions to engage in prevention behaviors was related to lower numeracy ability. Additionally, intentions to engage in prevention behaviors were stronger among older adults than younger adults. No significant difference was found across numeracy ability or age groups in intentions to engage in detection behaviors. Additionally, there were not significant differences in intentions to engage in prevention or detection behaviors when the efficacy level of these behaviors varied. History of engaging in prevention behaviors was related to intentions to engage in future prevention behaviors in the positive frame condition and in the negative frame condition. In conclusion, older adults reacted similarly to younger adults following exposure to framed messages, and endorsed stronger intentions than the younger adults to engage in prevention behaviors regardless of message frame. Additionally, positively-framed prevention messages were more persuasive than negatively-framed messages among people with a history of engaging in prevention behaviors. Recommendations for future research include examining variables associated with increased compliance among individuals with a weaker history of engaging in the recommended behaviors should be explored in future studies

The effects of framing on decision making: Collaborative versus individual decision making among older adults

The framing effect in medical decision making was examined using individual and collaborative older adult decision makers. One hundred eight adults over the age of 60 participated. A lung cancer scenario was presented to each participant, with the option of choosing surgery or radiation for treatment. Participants viewed the options in either a positive (survival) or negative (mortality) frame. A mixed design was used, with frame (positive or negative) and condition (individual or collaborative) as the between subject factors, and data format (cumulative probability, interval probability, and life expectancy) as the within subject factor. Individuals demonstrated the framing effect in one data format, life expectancy, by choosing surgery in the positive frame and radiation in the negative frame more often than expected by chance. Collaborative decision makers demonstrated the framing effect in two data formats, cumulative and interval probability. Collaborators indicated higher confidence ratings in the data format where the framing effect was not exhibited as compared to the data formats where the framing effect was exhibited. There were no other differences in confidence and use of information ratings across data formats or between decision makers who demonstrated the framing effect and decision makers who did not demonstrate the framing effect

Holocene Sediment Magnetic Properties Along a Transect from Isafjardardjup to Djupall, Northwest Iceland

Holocene changes in terrestrial provenance and processes of sediment transport and deposition are tracked along a fjord-to-shelf transect adjacent to Vestfirdir, Iceland, using the magnetic properties ofmarine sediments.Magnetic susceptibility (MS) profiles of 10 cores (gravity and piston) were obtained onboard using a Bartington MS loop. Remanent magnetizations were measured at 1-cm intervals from u-channel samples taken from six cores on a cryogenic magnetometer. Between six and nine alternating field demagnetization steps were used to isolate the characteristic magnetization directions. The chronologies of the cores used in this study were determined from AMS14 C dates on mollusks and foraminifera and contrained by the regional occurrance ofthe 10,200 6 60 cal yr. BP Saksunavatn tepha. Correlative fluctuations in magneticconcentration are noted between the fjord and shelf sites, though these fluctuations are partiallymasked by regional variations in carbonate content. The onset of Neoglaciation is interpreted by changes in magnetic properties including an increase in mass magneticsusceptibility that began approximately 3000 cal yr. BP. The maximum angular deviation and the median destructive field (generally 20 mT) suggest that the natural remanent magnetization is carried by a coarse ferrimagnetite mineralogy, likely magnetite or titano-magnetite. Reproducible paleomagnetic inclination values are observed in several records, including a nearly vertical inclination around 8000 cal yr. BP, suggesting that the magnetic pole may have been proximal to Iceland, followed by an interval of much shallower inclination (6000–7000 cal yr. BP)

Management and Outcome of Permanent Pacemaker and Implantable Cardioverter-Defibrillator Infections

ObjectivesWe describe the management and outcome of permanent pacemaker (PPM) and implantable cardioverter-defibrillator (ICD) infections in a large cohort of patients seen at a tertiary care facility with expertise in device lead extraction.BackgroundInfection is a serious complication of PPM and ICD implantation. Optimal care of patients with these cardiac device infections (CDI) is not well defined.MethodsA retrospective review of all patients with CDI admitted to Mayo Clinic Rochester between January 1, 1991, and December 31, 2003, was conducted. Demographic and clinical data were collected, and descriptive analysis was performed.ResultsA total of 189 patients met the criteria for CDI (138 PPM, 51 ICD). The median age of the patients was 71.2 years. Generator pocket infection (69%) and device-related endocarditis (23%) were the most common clinical presentations. Coagulase-negative staphylococci and Staphylococcus aureus, in 42% and 29% of cases, respectively, were the leading pathogens for CDI. Most patients (98%) underwent complete device removal. Duration of antibiotic therapy after device removal was based on clinical presentation and causative organism (median duration of 18 days for pocket infection vs. 28 days for endocarditis; 28 days for S. aureusinfection vs. 14 days for coagulase-negative staphylococci infection [p < 0.001]). Median follow-up after hospital discharge was 175 days. Ninety-six percent of patients were cured with both complete device removal and antibiotic administration.ConclusionsCure of CDI is achievable in the large majority of patients treated with an aggressive approach of combined antimicrobial treatment and complete device removal. Based on findings of our large retrospective institutional survey and previously published data, we submit proposed management guidelines of CDI

Predictors of Daily Adherence to Naltrexone for Alcohol Use Disorder Treatment During a Mobile Health Intervention

Background Adherence to medications for treating alcohol use disorder (AUD) is poor. To identify predictors of daily naltrexone adherence over time, a secondary data analysis was conducted of a trial evaluating a mobile health intervention to improve adherence. Methods Participants seeking treatment for AUD (n = 58; M-age = 38 years; 71% male) were prescribed naltrexone for 8 weeks. Adherence was tracked using the Medication Event Monitoring System (MEMS). In response to daily text messages, participants reported the previous day's alcohol use, craving, and naltrexone side effects. Using multilevel structural equation modeling (MSEM), we examined baseline dispositional factors and within-person, time-varying factors as predictors of daily adherence. Results Naltrexone adherence decreased over time. Adherence was higher on days when individuals completed daily mobile assessments relative to days when they did not (odds ratio [OR] = 2.53, 95% confidence interval [CI] 1.61 to 3.98), irrespective of intervention condition. Days when individuals drank more than their typical amount were related to lower next-day adherence (OR = 0.93, 95% CI 0.88 to 0.99). A similar pattern was supported for craving (OR = 0.88, 95% CI 0.79 to 0.98). Weekend days were associated with lower adherence than weekdays (OR = 0.71, 95% CI 0.58 to 0.86); this effect was partly mediated by heavier daily drinking (indirect effect = -0.02, 95% CI -0.04 to -0.003) and stronger-than-usual craving (indirect effect = -0.01, 95% CI -0.02 to 0.00) on weekend days. Conclusions The results further demonstrate the need to improve adherence to AUD pharmacotherapy. The present findings also support developing interventions that target daily-level risk factors for nonadherence. Mobile health interventions may be one means of developing tailored and adaptive adherence interventions

A Long-Term Vision for an Ecologically Sound Platte River

The Platte River extends about 310 mi (499 km) from North Platte, Nebraska, to its terminus at the Missouri River confluence near Plattsmouth, Nebraska. The Platte River Valley is a continentally significant ecosystem that serves as a major stopover for migratory waterbirds in the Central Flyway including the endangered Whooping Crane (Grus americana) and \u3e1 million Sandhill Cranes (Antigone canadensis) at the peak of spring migration. However, the Platte River Valley also supports a great diversity of avifauna including grassland breeding birds, native stream fish, vascular plants, herpetofauna, mammals, pollinators, and aquatic macroinvertebrates. Despite ongoing conservation efforts since the mid-1970s the ecosystem remains largely conservation dependent and an increasing number of species across taxa are being considered at risk of regional extirpation or outright extinction. However, given the attention provided to conservation in the Platte River Valley and the need to maintain ecologically functional stopover sites in the Central Flyway, there is a great opportunity to create a resilient refugium for biodiversity conservation in the central Great Plains. To that end we convened a working group of \u3e18 individuals representing \u3e9 organizations including representatives from non-profit conservation organizations, universities, and state and federal natural resource agencies to develop a long-term vision for an ecologically sound Platte River Valley (PRV). We met in groups of varying size for \u3e170 hours throughout a more than 3-year period and developed conservation priorities and objectives using a landscape design process. Landscape design is an interdisciplinary conservation planning process that incorporates components of landscape ecology and social dimensions of natural resources with the explicit intention of improving conservation implementation.https://digitalcommons.unl.edu/zeabook/1128/thumbnail.jp

A new approach for developing “implementation plans” for cognitive stimulation therapy (CST) in low and middle-income countries: Results from the CST-International study

Background: Even with a strong evidence base, many healthcare interventions fail to be translated to clinical practice due to the absence of robust implementation strategies. For disorders such as Alzheimer's disease and other dementias, access to evidence-based interventions beyond research settings is of great importance. Cognitive Stimulation Therapy (CST) is a brief, group-based intervention, with consistent evidence of effectiveness. Methods: An implementation focused, three-phase methodology was developed using extensive stakeholder engagement. The methods resulted in a standardized Implementation Plan for the successful translation of CST from research to practice. The methodology was developed using the Consolidated Framework for Implementation Research (CFIR) and refined in three countries that vary in levels of economic development and healthcare systems (Brazil, India and Tanzania. Results: Five Implemention Plans for CST were produced. Each plan contained implementation strategies and action plans devised in conjunction with policy professionals, healthcare professionals, people with dementia and family carers, and an international team of researchers and clinicians. Conclusion: This novel methodology can act as a template for implementation studies in diverse healthcare systems across the world. It is an effective means of devising socio-culturally informed Implementation Plans that account for economic realities, health equity and healthcare access

SEGMA: an automatic SEGMentation Approach for human brain MRI using sliding window and random forests

Quantitative volumes from brain magnetic resonance imaging (MRI) acquired across the life course may be useful for investigating long term effects of risk and resilience factors for brain development and healthy aging, and for understanding early life determinants of adult brain structure. Therefore, there is an increasing need for automated segmentation tools that can be applied to images acquired at different life stages. We developed an automatic segmentation method for human brain MRI, where a sliding window approach and a multi-class random forest classifier were applied to high-dimensional feature vectors for accurate segmentation. The method performed well on brain MRI data acquired from 179 individuals, analyzed in three age groups: newborns (38–42 weeks gestational age), children and adolescents (4–17 years) and adults (35–71 years). As the method can learn from partially labeled datasets, it can be used to segment large-scale datasets efficiently. It could also be applied to different populations and imaging modalities across the life course

Genome Sequences of Mycobacteriophages Amgine, Amohnition, Bella96, Cain, DarthP, Hammy, Krueger, LastHope, Peanam, PhelpsODU, Phrank, SirPhilip, Slimphazie, and Unicorn

We report the genome sequences of 14 cluster K mycobacteriophages isolated using Mycobacterium smegmatis mc2155 as host. Four are closely related to subcluster K1 phages, and 10 are members of subcluster K6. The phage genomes span considerable sequence diversity, including multiple types of integrases and integration sites