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Managing legume pests in sub-Saharan Africa: Challenges and prospects for improving food security and nutrition through agro-ecological intensification
Pest management technology has been through a number of advances that have, perhaps, moved away from the mass extermination of pests achieved through the advent of synthetic chemicals in the latter half of the 20th century to more agro-ecologically sensitive innovations that attempt to regulate pest populations by interfering with their breeding, attracting predators or repelling the pests from crops whilst attracting them to other plants. However, pest management is more than technology innovations and must enable integration of technologies in a practical and cost-beneficial manner. This paper summarises existing and cutting edge technologies for pest management in the context of legume production in Africa highlighting where advances can be made to improve pest management at the smallholder level. Challenges and opportunities are highlighted, and priorities for research are recommended that complement agro-ecological intensification (AEI). AEI describes the sustainable increase in agricultural production from the same amount of available land area while reducing the negative environmental impacts of agricultural technology (âReaping the Benefitsâ â The Royal Society, 2009; Green Food Report - Defra, 2011; âSustainable Intensificationâ - Montpellier Report, 2013). AEI aims to harness knowledge of ecological processes to increase food production and improve livelihoods and challenges global agriculture to achieve a doubling in world food production while sustaining the environment in which we live.
Synthetics are relatively cheap and provide proven pest control. They are substantially underutilised in Africa and could lead to significant productivity increases if their usage could be increased to levels found in other regions of the world. Challenges and opportunities to increased uptake are
âą Monetary cost to small holder farmers â cost-benefit not clear when produce is typically not sold or when market values are marginal
âą Limited end user knowledge on how to use synthetics leads to excessive use, reduced cost-benefit and subsequent environmental and safety hazards, under-dosing and resistance development, use of wrong pesticide for crop and pest, high poisoning rates to users and consumers
âą Poor regulation leads to adulteration, dumping, limited availability, repackaging without labelling
Pesticidal plants are cheap, generally only requiring labour to collect and process, and fit well within IPM and AEI strategies. Most African farmers are familiar with botanicals, but usage is constrained by a number of factors related to gaps in research and development and how they are regulated. Challenges and opportunities to uptake are
âą Although generally low-risk, safety data are lacking.
âą Hundreds of plant species have been evaluated for efficacy, factors influencing reliability of efficacy are unknown, e.g. that influence the production of bioactive constituents (altitude, season, soil type), that effect the amount of bioactive compounds extracted (solubility, volatility) or the duration/level of control to be expected for different pest species.
âą A high level of knowledge is required to use pesticidal plants (when/where to harvest, how to prepare/extract) although much of this may already be known
âą Availability of sufficient plants can be limited and/or unreliable due to over-collection, unsustainable collection or competing uses (medicine, fodder, food, fibre) as well as poor propagation properties or habitat conservation
âą Regulatory frameworks treat pesticidal plants in the same way as synthetics, and high registration costs of existing systems prevent developing products which cannot be protected by patent making it difficult to invest in registration costs
âą Complex chemistry makes registration of products difficult
âą Variability in efficacy is a limiting factor but can be managed by selection of effective provenances for propagation
Biopesticides are highly appropriate for IPM and AEI of legume crop production. Several products exist that could contribute to improved legume production in Africa. Challenges and opportunities to uptake are
âą The cost of products generally puts them out of reach of small holder farmers
âą Shelf life of products is often limited, requiring relatively sophisticated marketing chains to improve delivery of high quality products
âą Cost-benefits not clear due to input price vs. potential income or gain in food security/nutrition
âą Research and development is focussed on servicing developed country needs, often advanced technology/knowledge is required to mass produce biopesticides.
âą Effects often not immediately evident and pest takes days to control leaving farmers uncertain of their benefits
Biocontrol organisms are highly appropriate for IPM and AEI of legume crop production. Artificial augmentation of predators and parasitoids can work well, but is generally expensive to produce and works best with high value crops in enclosed environments, such as glasshouses, where it is relatively easier to maintain investment and prevent escape of organisms. Augmentation in small holder legume farming systems is probably not cost-beneficial in the short to medium term in Africa. However improving farming practice to improve ecosystem services of natural biocontrol is feasible. Challenges and opportunities to uptake of natural biocontrol are
âą More research is required on the alternative crop requirements and optimal environments for predators and parasitoids as it is still not clear how best to optimise predator numbers for key pests or what level of pest control can be achieved
âą Increasing end user knowledge on how to improve (engineer) environments that increase predation combined and enhance pollinators
âą Understanding costs and benefits of improved biocontrol, particularly when physical inputs are required (e.g. planting/maintaining trap crops or overwintering crops)
âą Increasing farmer knowledge on the impact of general farm practices on biocontrol (frequent use of generic synthetic pesticides, field clearing with fire)
Semiochemicals are highly appropriate for IPM and AEI of legume crop production. Pheromone traps can be cost-effective for monitoring important pests like army worm or pod borer, particularly if implemented at the community level. The cost-benefits of pheromones to manage pest populations (through mating disruption or removal trapping) is less clear and currently only works for some key pests of high value crops. The use of naturally released semiochemicals through push-pull cropping strategies has been shown to be highly beneficial for reducing key maize pests in smallholder farming. Despite this, evidence of uptake by African farmers has been limited even when heavily promoted through intensive knowledge training programmes. Challenges and opportunities to uptake are
âą The cost of products generally puts them out of reach of smallholder farmers
âą Efficacy may be limited
âą Knowledge to use effectively is high
Resistance mechanisms are arguably the most effective method for delivering improved pest management to small holder farmers. Farmers may have to buy seed, but then often donât need to make any further inputs to receive benefits of lower pest problems. If non-hybrid resistant varieties are developed, farmers can self-propagate the crop for many years. Challenges and opportunities to uptake are
âą The costs of developing new varieties is coming down through the use of gene marker technologies; however, developing resistant varieties still requires a significant research investment, often supported by the public sector.
âą Adding resistance often means enhancing the natural production of detrimental compounds with in the plant, which may have effects on consumer health and safety and/or pollinators/ecosystem services.
âą The cost-benefits may be high for farmers, but if adding in the R&D investment, it is not clear whether overall cost-benefits to society are positive, particularly if insects rapidly adapt to resistance mechanisms requiring further investment in varietal development.
âą Some of the more rapid methods of resistance breeding, e.g. genetic modification, remain controversial
The development of strategies to enhance agro-ecosystem resilience is by definition an integral part of IPM and AEI in legume production. In many cases farmers already employ traditional practices which improve agroecosystem resilience. Frequently, the practices do not require expensive inputs or elaborate technology. Challenges and opportunities to uptake are
âą The strategies may be multi-facetted and complex with diverse objectives rather than being a more tangible single technology directed at a specific problem. This impinges on issues of training and clarity in what is being offered
âą Strategies tend to be beneficial to the health of the agro-ecosystem in general (soils, nutrition, water, pollination) but often have limited direct effect on pests
âą Conflicts may exist between objectives so, for example, use of green manure while having advantages for soil, nutrition and water, can also increase soil pest problems
âą Perhaps more than other approaches, agro-ecosystem resilience strategies are not âone size fits allâ, and must be tailored to local conditions, e.g. appropriate intercropping strategies are dependent on the cropping system and culinary context
âą Some strategies, e.g. incorporation of areas of natural vegetation in the agro-ecosystem landscape, require implementation of wide geographical scales in order to achieve most benefit
Agroecological pest management by small holder farmers in Africa requires building substantial understanding of crop-pest-environmental interactions, which requires investment in training by institutions and farmers. This presents certain challenges and opportunities:
âą Farmer field school approaches are well developed in many parts of Africa and have been successfully used in Asia to develop capacity for agroecological pest management. The experience in Africa has been that only a limited number of farmers invest in building agroecological reasoning into their management, but FFS have been effective in promoting farmer to farmer technology transfer.
âą Agroecological knowledge based pest management has been more successful in higher value crops, with complex pest problems, and where use of pesticides may be limited by regulation or have limited effectiveness.
âą Research and validation is required is develop discovery-based learning approaches that will enable farmers to take informed decisions needed for agroecological pest management
Responses to colour and host odour cues in three cereal pest species, in the context of ecology and control
Many insects show a greater attraction to multimodal cues, e.g. odour and colour combined, than to either cue alone. Despite the potential to apply the knowledge to improve control strategies, studies of multiple stimuli have not been undertaken for stored product pest insects. We tested orientation towards a food odour (crushed white maize) in combination with a colour cue (coloured paper with different surface spectral reflectance properties) in three storage pest beetle species, using motion tracking to monitor their behaviour. While the maize weevil, Sitophilus zeamais (Motsch.), showed attraction to both odour and colour stimuli, particularly to both cues in combination, this was not observed in the bostrichid pests Rhyzopertha dominica (F.) (lesser grain borer) or Prostephanus truncatus (Horn) (larger grain borer). The yellow stimulus was particularly attractive to S. zeamais, and control experiments showed that this was neither a result of the insects moving towards darker-coloured areas of the arena, nor their being repelled by optical brighteners in white paper. Visual stimuli may play a role in location of host material by S. zeamais, and can be used to inform trap design for the control or monitoring of maize weevils. The lack of visual responses by the two grain borers is likely to relate to their different host-seeking behaviours and ecological background, which should be taken into account when devising control methods
Spectra of Coherent Smith-Purcell Radiation Observed from Short Electron Bunches: Numerical and Experimental Studies
MOPWA056 - ISBN978-3-95450-122-9International audienceThere is a significant interest in the development of compact particle accelerators within research areas including X-ray and THz (T-ray) sources of radiation, particle physics and medical sciences. To support the progress in these areas, non-invasive, electron beam diagnostics that are capable of measuring a single femtosecond electron bunch are required. At the current stage such beam diagnostics for femtosecond-long electron bunches are still not available. The goal of the work presented is to understand the spectral characteristics of coherent Smith-Purcell radiation to enable its quick and reliable interpretation including the longitudinal profile reconstruction of electron bunches. The research presented comprises results from numerical modelling and experimental studies. Using the numerical data, we discuss the radiated spectra dependence on the electron bunch profile and analyse the results. We also discuss the experimental data and compare it with theoretical predictions
Electronic Structure of Transition-Metal Dicyanamides Me[N(CN)] (Me = Mn, Fe, Co, Ni, Cu)
The electronic structure of Me[N(CN)] (Me=Mn, Fe, Co, Ni, Cu)
molecular magnets has been investigated using x-ray emission spectroscopy (XES)
and x-ray photoelectron spectroscopy (XPS) as well as theoretical
density-functional-based methods. Both theory and experiments show that the top
of the valence band is dominated by Me 3d bands, while a strong hybridization
between C 2p and N 2p states determines the valence band electronic structure
away from the top. The 2p contributions from non-equivalent nitrogen sites have
been identified using resonant inelastic x-ray scattering spectroscopy with the
excitation energy tuned near the N 1s threshold. The binding energy of the Me
3d bands and the hybridization between N 2p and Me 3d states both increase in
going across the row from Me = Mn to Me = Cu. Localization of the Cu 3d states
also leads to weak screening of Cu 2p and 3s states, which accounts for shifts
in the core 2p and 3s spectra of the transition metal atoms. Calculations
indicate that the ground-state magnetic ordering, which varies across the
series is largely dependent on the occupation of the metal 3d shell and that
structural differences in the superexchange pathways for different compounds
play a secondary role.Comment: 20 pages, 11 figures, 2 table
Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy
Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the host cell microenvironment to support its own survival and growth. Recent advances in label-free spectroscopic imaging techniques have made it possible to study biological systems at a high spatial resolution. In this study, we used conventional Fourier-transform infrared (FTIR) microspectroscopy and synchrotron-based FTIR microspectroscopy to analyze the chemical changes that are associated with infection of human brain microvascular endothelial cells (hBMECs) by T. gondii (RH) tachyzoites. Both FTIR microspectroscopic methods showed utility in revealing the chemical alterations in the infected hBMECs. Using a ZnS hemisphere device, to increase the numerical aperture, and the synchrotron source to increase the brightness, we obtained spatially resolved spectra from within a single cell. The spectra extracted from the nucleus and cytosol containing the tachyzoites were clearly distinguished. RNA sequencing analysis of T. gondii-infected and uninfected hBMECs revealed significant changes in the expression of host cell genes and pathways in response to T. gondii infection. These FTIR spectroscopic and transcriptomic findings provide significant insight into the molecular changes that occur in hBMECs during T. gondii infection
Volume-weighted unipolar voltage predicts heart failure mortality in patients with dilated cardiomyopathy and ventricular arrhythmias
BACKGROUND Patients with dilated cardiomyopathy (DCM) who are undergoing catheter ablation of ventricular arrhythmias (VAs) are at risk of rapidly progressive heart failure (HF). Endocardial voltages decrease with loss of viable myocardium. Global left ventricular (LV) voltage as a surrogate for the amount of remaining viable myocardium may predict prognosis.OBJECTIVES This study evaluated whether the newly proposed parameter volume-weighted (vw) unipolar voltage (UV) can predict HF-related adverse outcomes (HFOs), including death, heart transplantation, or ventricular assist device implantation, in DCM. METHODS In consecutive patients with DCM referred for VA ablation, vwUV was calculated by mathematically integrating UV over the left ventricle, divided by the endocardial LV surface area and wall thickness. Patients were followed for HFOs.RESULTS A total of 103 patients (57 +/- 14 years of age; left ventricular ejection fraction [LVEF], 39% +/- 13%) were included. Median vwUV was 9.75 (IQR: 7.27-12.29). During a median follow-up of 24 months (IQR: 8-47 months), 25 patients (24%) died, and 16 had HFOs 7 months (IQR: 1-18 months) after ablation. Patients with HFOs had significantly lower LVEF (29% +/- 10% vs 41% +/- 12%), vw bipolar voltage (BV) (3.00 [IQR: 2.47-3.53] vs 5.00 [IQR: 4.12-5.73]), and vwUV (5.94 [IQR: 5.28-6.55] vs 10.37 [IQR: 8.82-12.81]; all P < 0.001), than patients without HFOs. In Cox regression analysis and goodness-of-fit tests, vwUV was the strongest and independent predictor for HFOs (HR: 3.68; CI: 2.09-6.45; likelihood ratio chi-square, 33.05; P < 0.001).CONCLUSIONS The novel parameter vwUV, as a surrogate for the amount of viable myocardium, identifies patients with DCM with VA who are at high risk for HF progression and mortality.Metabolic health: pathophysiological trajectories and therap
Camellia sinensis solvent extract, epigallocatechin gallate and caffeine confer trophocidal and cysticidal effects against Acanthamoeba castellanii
We examined the anti-acanthamoebic efficacy of green tea Camellia sinensis solvent extract (SE) or its chemical constituents against Acanthamoeba castellanii by using anti-trophozoite, anti-encystation, and anti-excystation assays. C. sinensis SE (625â5000 ”g/mL) inhibited trophozoite replication within 24â72 h. C. sinensis SE exhibited a dose-dependent inhibition of encystation, with a marked cysticidal activity at 2500â5000 ”g/mL. Two constituents of C. sinensis, namely epigallocatechin-3-gallate and caffeine, at 100 ÎŒM and 200 ÎŒM respectively, significantly inhibited both trophozoite replication and encystation. Cytotoxicity analysis showed that 156.25â2500 ”g/mL of SE was not toxic to human corneal epithelial cells, while up to 625 ”g/mL was not toxic to Madin-Darby canine kidney cells. This study shows the anti-acanthamoebic potential of C. sinensis SE against A. castellanii trophozoites and cysts. Pre-clinical studies are required to elucidate the in vivo efficacy and safety of C. sinensis SE
Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV
We report the results of a study of color coherence effects in ppbar
collisions based on data collected by the D0 detector during the 1994-1995 run
of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8
TeV. Initial-to-final state color interference effects are studied by examining
particle distribution patterns in events with a W boson and at least one jet.
The data are compared to Monte Carlo simulations with different color coherence
implementations and to an analytic modified-leading-logarithm perturbative
calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters
Measurement of the p-pbar -> Wgamma + X cross section at sqrt(s) = 1.96 TeV and WWgamma anomalous coupling limits
The WWgamma triple gauge boson coupling parameters are studied using p-pbar
-> l nu gamma + X (l = e,mu) events at sqrt(s) = 1.96 TeV. The data were
collected with the DO detector from an integrated luminosity of 162 pb^{-1}
delivered by the Fermilab Tevatron Collider. The cross section times branching
fraction for p-pbar -> W(gamma) + X -> l nu gamma + X with E_T^{gamma} > 8 GeV
and Delta R_{l gamma} > 0.7 is 14.8 +/- 1.6 (stat) +/- 1.0 (syst) +/- 1.0 (lum)
pb. The one-dimensional 95% confidence level limits on anomalous couplings are
-0.88 < Delta kappa_{gamma} < 0.96 and -0.20 < lambda_{gamma} < 0.20.Comment: Submitted to Phys. Rev. D Rapid Communication
Measurement of the ttbar Production Cross Section in ppbar Collisions at sqrt{s} = 1.96 TeV using Kinematic Characteristics of Lepton + Jets Events
We present a measurement of the top quark pair ttbar production cross section
in ppbar collisions at a center-of-mass energy of 1.96 TeV using 230 pb**{-1}
of data collected by the DO detector at the Fermilab Tevatron Collider. We
select events with one charged lepton (electron or muon), large missing
transverse energy, and at least four jets, and extract the ttbar content of the
sample based on the kinematic characteristics of the events. For a top quark
mass of 175 GeV, we measure sigma(ttbar) = 6.7 {+1.4-1.3} (stat) {+1.6- 1.1}
(syst) +/-0.4 (lumi) pb, in good agreement with the standard model prediction.Comment: submitted to Phys.Rev.Let
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