Sens of burden of the families taking care of patient with Alzheimer’s disease

Wstęp. Chorzy z demencją w przebiegu choroby Alzheimera wymagają stałej, niejednokrotnie całodobowej opieki. Jak wykazują badania, 92% osób dotkniętych chorobą Alzheimera przebywa w domu w trakcie trwania choroby, w związku z czym ciężar opieki spoczywa na rodzinie. Cel pracy. Celem pracy jest ukazanie czynników wpływających na poczucie obciążenia opiekuna osoby chorej na chorobę Alzheimera oraz form pomocy niesionej przez pielęgniarkę rodzinną. Materiał i metody. Badanie przeprowadzono wśród 100 opiekunów osób z chorobą Alzheimera. Narzędziem badawczym był Kwestionariusz Poczucia Obciążenia wraz z kwestionariuszem ankiety. Wyniki. Wykazano zależność między wiekiem, płcią, statusem zawodowym, stanem zdrowia oraz stopniem pokrewieństwa opiekuna a wysokim poczuciem obciążenia opieką nad chorym z chorobą Alzheimera. Istnienie wsparcia niesionego opiekunowi wpływa na niższe poczucie obciążenia opieką. Potrzebę stworzenia domu pobytu czasowego dla chorych wykazano w grupie osób z wysokim poczuciem obciążenia. Wnioski. Badania wykazały znaczne obciążenie opiekuna i rodziny osoby z chorobą Alzheimera. W pracy pielęgniarki sprawującej opiekę nad rodziną istotne jest określenie obszarów, w których występują deficyty w celu prawidłowego ukierunkowania niesionego wsparcia zarówno instytucjonalnego, jak i emocjonalnego.Introduction. Patients with dementia in Alzheimer’s disease often require regular night care. Research shows 92% of people with Alzheimer’s disease living at home during the course of the disease and therefore the burden of care rests with the family. Aim of the study. Aim of the study is to show the factors affecting the sense of caregiver burden a person suffering from Alzheimer’s disease and forms of aid carried by a family nurse. Material and methods. The study was performed among 100 caregivers of people with Alzheimer’s disease. Research tool was a questionnaire with a Sense of Burden Questionnaire. Results. The dependence between age, gender, occupational status, health status and the degree of kinship caregiver burden and a high sense of care for patients with Alzheimer’s disease. Existence of carer support being carried affects the lower sense of burden on care. The need for a temporary stay home for the sick has been demonstrated in patients with a high sense of burden. Conclusions. Studies have shown a significant burden guardian and family of the person with Alzheimer’s disease. The study nurse who has the care of the family is important to identify areas where there are deficits in the correct direction being carried both institutional support and emotional

Fatty Acid Profile of Postmenopausal Women Receiving, and Not Receiving, Hormone Replacement Therapy

Menopause, the permanent cessation of the menstrual cycle, marks the end of a woman’s reproductive lifespan. Menopausal hormonal therapy (MHT) can potentially skew the fatty acid profile increasing the risk for developing metabolic diseases and disorders of skeletal, gastrointestinal, and nervous systems. The aim of this study was to investigate the fatty acid profile of postmenopausal women receiving, and not receiving, hormone replacement therapy. A total of 156 healthy women with a mean age of 60 participated in this cross-sectional study. Gas chromatography with an Agilent Technologies 7890A GC system was used to determine fatty acid content. Statistical analysis was conducted using R software, version 3.4.1. Women receiving MHT had significantly higher (p < 0.05) concentrations of C14:0 and C16:0. MHT was found to be associated with a tendency (p = 0.053) to diminish concentrations of C18:1n-9, C20:4, and all unsaturated fatty acids (p < 0.05). The longer MHT was used, the higher the concentration of C24:1 (p = 0.04) and the lower the concentration of C18:2n-6 (p = 0.03)

Correlations between Fatty Acid Profile and Body Fat Distribution in Postmenopausal Women—A Cross Sectional Study

The aim of the study was to assess the fatty acid profile of the whole blood of postmenopausal women, taking into account anthropometric parameters. The study involved 156 healthy women with an average age of 60 (SD = 6.3 years) years who were living in the West Pomerania Province (Poland). An original questionnaire was presented to all patients, conducting anthropometric measurements of them: weight, height, waist and hip circumference, body mass index (BMI), waist–hip ratio (WHR) and body adipose index (BAI), as well as an assessment of the fatty acid profile by employing gas chromatography. It has been observed that in menopausal women, the concentration of C16:1 increases with respect to their BMI (r = 0.205 p = 0.01). Similar correlations were noted with regard to body weight (C16:1 r = 0.177 p = 0.029). It was also shown that the concentration of C18trans11 (r = −0.166 p = 0.039), 18:2n6 (r = −0.165 p = 0.04) and n6/n9 (r = −0.194 p = 0.015) were negatively correlated with respect to their WHR, while the levels C16:1 (r = 0.22 p = 0.006), C18:1n9 (r = 0.22 p = 0.007), C24:1 (r = 0.251 p = 0.002), MUFA (r = 0.227 p = 0.046) and n9 (r = 0.224 p = 0.005) were correlated positively with respect to their BAI. The fatty acid profile of the whole blood of postmenopausal women is modulated to a poor extent by anthropometric variables. Therefore, more prospective research is warranted

The Relationship between Eicosanoid Levels and Serum Levels of Metabolic and Hormonal Parameters Depending on the Presence of Metabolic Syndrome in Patients with Benign Prostatic Hyperplasia

Background: The purpose of our investigation was to analyze the relationship between the serum levels of inflammatory mediators (HETE, HODE) and the levels of selected metabolic and hormonal parameters in patients with benign prostatic hyperplasia (BPH) with regard to concomitant metabolic syndrome (MetS). Methods: The study involved 151 men with BPH. Blood samples were taken for laboratory analysis of the serum levels of metabolic and hormonal parameters. Gas chromatography was performed using an Agilent Technologies 7890A GC System. Results: We found that waist circumference was the only parameter related to the levels of fatty acids, namely: 13(S)-HODE, 9(S)-HODE, 15(S)-HETE, 12(S)-HETE, and 5-HETE. In the patients with BPH and MetS, triglycerides correlated with 9(S)-HODE, 15(S)-HETE, 12(S)-HETE, and 5-HETE, which was not observed in the patients without MetS. Similarly, total cholesterol correlated with 9(S)-HODE, and 15(S)-HETE in the patients with BPH and MetS, but not in those without MetS. In the group of BPH patients with MetS, total testosterone positively correlated with 13(S)-HODE, and free testosterone with 9(S)-HODE. Conclusions: Based on this study, it can be concluded that lipid mediators of inflammation can influence the levels of biochemical and hormonal parameters, depending on the presence of MetS in BPH patients

The Biodiversity and Distribution of Abyssal Benthic Foraminifera and Their Possible Ecological Roles: A Synthesis Across the Clarion-Clipperton Zone

10.3389/fmars.2021.634726Frontiers in Marine Science863472